General information for g10168.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Ribosomal protein S6 kinase alpha-3.
Parent gene
- The parent gene g10168 is located on chr_1: 8030638..8031567 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10168 | g10168.t4 | TSS | g10168.t4 | 8025813 | 8025813 |
| chr_1 | g10168 | g10168.t4 | isoform | g10168.t4 | 8025954 | 8028877 |
| chr_1 | g10168 | g10168.t4 | exon | g10168.t4.exon1 | 8025954 | 8026007 |
| chr_1 | g10168 | g10168.t4 | cds | g10168.t4.CDS1 | 8025954 | 8026007 |
| chr_1 | g10168 | g10168.t4 | exon | g10168.t4.exon2 | 8027701 | 8028322 |
| chr_1 | g10168 | g10168.t4 | cds | g10168.t4.CDS2 | 8027701 | 8028322 |
| chr_1 | g10168 | g10168.t4 | exon | g10168.t4.exon3 | 8028473 | 8028669 |
| chr_1 | g10168 | g10168.t4 | cds | g10168.t4.CDS3 | 8028473 | 8028669 |
| chr_1 | g10168 | g10168.t4 | exon | g10168.t4.exon4 | 8028737 | 8028877 |
| chr_1 | g10168 | g10168.t4 | cds | g10168.t4.CDS4 | 8028737 | 8028877 |
| chr_1 | g10168 | g10168.t4 | TTS | g10168.t4 | NA | NA |
Sequences
>g10168.t4 Gene=g10168 Length=1014
ATGCCATTAGCCGGAAAAACTTTGAATATATGGCCAATAAAGCAAGAAGTCGCGAGCTCA
TCTCAGCAATTACAAGGCTTAGAGATGGTTGTCGACGATGGATCGGTCATCAAATATCCA
CAAAATACGATCAATATTAACATTAATAACAATAATAATAATAACTCAATGGATAAGCTT
CAAATTTCTGGACATGACGATGATTCTGATGACGTTGAGATGAAATCTGACGATTTAGTT
GTAGAAGTAAAGGATCTCGTAAAAGATGGTCATGAAAAAGCGGATCCGTCACAATTTGAG
CTGCTTAAAGTCCTCGGTGAAGGCAGCTTTGGAAAAGTTTTTCTTGTGAGAAAAATTGTT
GGACTTGATGCTGGTACATTATATGCTATGAAAGTACTAAAGAAAGCAACATTGAAAGTC
AAGGACCGAATGAGATCGACAAATGAGAGAAATATTTTAGCCGATATTGCTGTGGGTCAT
TCCTTTATAGTTAAGCTACATTACGCATTTCAAACTCCTGGCAAACTCTATCTCATTCTC
GATTTCCTTCGCGGTGGTGATTTATTCACTCGATTAAGCAAGGAAGTCATGTTCACAGAA
GAGGATGTTAAATTTTACCTAGCAGAGCTAGCACTCGCTTTAAATCATCTTCATTCACTT
GGAATTATTTATCGAGACTTCAATAATAATAATCCTTTTTATATAGATGCTGATGGTCAT
ATTGCACTAACTGATTTTGGTCTATCAAAAATTCCACTTGGTGACTCGAAAACTTATAGT
TTTTGTGGAACTGTAGAATATATGGCGCCTGAAGTTGTAAATCGTAAAGGACATACTTTT
GCCGCTGACTGGTGGTCATTTGGTGTACTTATGTATGAAATGCTTACTGGGAATTTGCCT
TTTCATGGAACAAACAGACAAGACACGATGAATCAAATATTAAAGACAAAATTGGGTATG
CCAGAAAATCTATCTCCAGAAGCACAATCGCTTTTGCGAGCATTATTCAAAAGA
>g10168.t4 Gene=g10168 Length=338
MPLAGKTLNIWPIKQEVASSSQQLQGLEMVVDDGSVIKYPQNTINININNNNNNNSMDKL
QISGHDDDSDDVEMKSDDLVVEVKDLVKDGHEKADPSQFELLKVLGEGSFGKVFLVRKIV
GLDAGTLYAMKVLKKATLKVKDRMRSTNERNILADIAVGHSFIVKLHYAFQTPGKLYLIL
DFLRGGDLFTRLSKEVMFTEEDVKFYLAELALALNHLHSLGIIYRDFNNNNPFYIDADGH
IALTDFGLSKIPLGDSKTYSFCGTVEYMAPEVVNRKGHTFAADWWSFGVLMYEMLTGNLP
FHGTNRQDTMNQILKTKLGMPENLSPEAQSLLRALFKR
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g10168.t4 | Gene3D | G3DSA:3.30.200.20 | Phosphorylase Kinase; domain 1 | 99 | 186 | 8.1E-92 |
| 7 | g10168.t4 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 187 | 338 | 8.1E-92 |
| 2 | g10168.t4 | PANTHER | PTHR24351 | RIBOSOMAL PROTEIN S6 KINASE | 58 | 338 | 2.0E-166 |
| 3 | g10168.t4 | PANTHER | PTHR24351:SF110 | NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE | 58 | 338 | 2.0E-166 |
| 1 | g10168.t4 | Pfam | PF00069 | Protein kinase domain | 99 | 337 | 3.5E-58 |
| 5 | g10168.t4 | ProSitePatterns | PS00107 | Protein kinases ATP-binding region signature. | 105 | 131 | - |
| 8 | g10168.t4 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 99 | 338 | 45.644 |
| 4 | g10168.t4 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 93 | 336 | 5.74E-73 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
