General information for g10168.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Ribosomal protein S6 kinase alpha-2.
Parent gene
- The parent gene g10168 is located on chr_1: 8030638..8031567 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10168 | g10168.t5 | isoform | g10168.t5 | 8029375 | 8031092 |
| chr_1 | g10168 | g10168.t5 | exon | g10168.t5.exon1 | 8029375 | 8029378 |
| chr_1 | g10168 | g10168.t5 | exon | g10168.t5.exon2 | 8029437 | 8029542 |
| chr_1 | g10168 | g10168.t5 | cds | g10168.t5.CDS1 | 8029527 | 8029542 |
| chr_1 | g10168 | g10168.t5 | exon | g10168.t5.exon3 | 8029598 | 8029715 |
| chr_1 | g10168 | g10168.t5 | cds | g10168.t5.CDS2 | 8029598 | 8029715 |
| chr_1 | g10168 | g10168.t5 | exon | g10168.t5.exon4 | 8029771 | 8029943 |
| chr_1 | g10168 | g10168.t5 | cds | g10168.t5.CDS3 | 8029771 | 8029943 |
| chr_1 | g10168 | g10168.t5 | exon | g10168.t5.exon5 | 8030009 | 8030151 |
| chr_1 | g10168 | g10168.t5 | cds | g10168.t5.CDS4 | 8030009 | 8030151 |
| chr_1 | g10168 | g10168.t5 | exon | g10168.t5.exon6 | 8030208 | 8030475 |
| chr_1 | g10168 | g10168.t5 | cds | g10168.t5.CDS5 | 8030208 | 8030475 |
| chr_1 | g10168 | g10168.t5 | exon | g10168.t5.exon7 | 8030568 | 8031092 |
| chr_1 | g10168 | g10168.t5 | cds | g10168.t5.CDS6 | 8030568 | 8030638 |
| chr_1 | g10168 | g10168.t5 | TTS | g10168.t5 | 8031602 | 8031602 |
| chr_1 | g10168 | g10168.t5 | TSS | g10168.t5 | NA | NA |
Sequences
>g10168.t5 Gene=g10168 Length=1337
AGAGGTTGATATTCTCTTAAGATATGGCAACCATCCGAATATTGTAACACTTTATCGCGT
ATTTGAAGATACATCTCGTTGTGTGTACTTAGTTATGGAATATTTAAAGGGTGGTGAATT
ACTCGATCGAATTTTGTCAATACAATTTAGTGAACAAGAGTCGGCTGCTGTTTTGAAAAC
GGTAGTATCAGCTGTTTCATATCTACATGATCACGGTGTTGTACACAGGGATCTTAAACC
TTCTAATTTACTGTATGCTTCCATTAATCATACGCCTGATTCATTGAGACTATGCGACCT
GGGTTTTGCAAAACAGCTAAGAGCTGACAATGGCTTATTAATGACTCCTTGTTATACAGC
AAACTTTGTTGCACCAGAAGTATTGAAACGTCAAGGATATGATCAATTGTGTGACATTTG
GTCATTGGGAGTGTTACTTTATATTACTCTTAGTGGAAGAACGCCTTTTGCCAGCACGCC
TAATGATGAACCTGAGACAATTTTAAAAAGAATTGGAAGTGGTCAAATTGATTTAGATAA
TGGCCGATGGGCCACAATTTCTGTAGAAGCGAAAGAATTGATTAGTCATATGATGCATAT
TGTACCATCAAAACGTCCAACAGCAGCGCAAATTTTAAGACATCCATGGACCGTGAGACA
GTCACATGCATTTGATTTGAGATCTCAACAAACGGTTTCACATTCACTTCACCATGTCGT
ACAGAAACCAACAACAAAAGATATAAGTGAAATTAAGGGTACTGTTAATAATGTTTTCCG
TGCTATAAATTCGCCTCAAGCACTCGGAATTGGTGTTGGACCGGTAACTATGAGTGAATT
AGCACGCCGAAGAAGAAGAGGAGCTGAAAAAGGGCATAACTGAGATTCAATGAACATTTT
TGTAATGAATTTCTAGTTAGGTATACTTGGAAGCAAAAAAAAACTTTTTCTACCTTAAAC
TTTTTTGAATCAATCGTAAAGGATTTGATGAAAGAAAAGCAGCCTCAAAAAAAATTGTGA
GAGCTAAATTAAATGATAATAGCGAGAAAATTAAACAATGCAAAAAATCGATAAAGATTT
ATTTCCATATTAAATATATGAATAATTGAATATTGATCAATCGAATCTGAATGATCTCTA
TTTTAACTTTTTACTAAAACAAAAGAAAATTATTATATATAAAAAGAATAATCTTAAAGT
GGAAGCATTTTTTCAAATTTACAATTGTCTTATTATGGAATGGAATTTAAAAAATGTATT
CTTGACACATTGAATGCTTTCTTTTAACACAAACTATAAAATTTTAACATTTAATCATTT
ATTGACAATTTACTAAA
>g10168.t5 Gene=g10168 Length=262
MEYLKGGELLDRILSIQFSEQESAAVLKTVVSAVSYLHDHGVVHRDLKPSNLLYASINHT
PDSLRLCDLGFAKQLRADNGLLMTPCYTANFVAPEVLKRQGYDQLCDIWSLGVLLYITLS
GRTPFASTPNDEPETILKRIGSGQIDLDNGRWATISVEAKELISHMMHIVPSKRPTAAQI
LRHPWTVRQSHAFDLRSQQTVSHSLHHVVQKPTTKDISEIKGTVNNVFRAINSPQALGIG
VGPVTMSELARRRRRGAEKGHN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g10168.t5 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 4 | 186 | 4.7E-67 |
| 2 | g10168.t5 | PANTHER | PTHR24349:SF402 | NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE | 1 | 255 | 4.2E-85 |
| 3 | g10168.t5 | PANTHER | PTHR24349 | SERINE/THREONINE-PROTEIN KINASE | 1 | 255 | 4.2E-85 |
| 1 | g10168.t5 | Pfam | PF00069 | Protein kinase domain | 1 | 185 | 3.1E-48 |
| 6 | g10168.t5 | ProSitePatterns | PS00108 | Serine/Threonine protein kinases active-site signature. | 42 | 54 | - |
| 8 | g10168.t5 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 1 | 186 | 35.863 |
| 5 | g10168.t5 | SMART | SM00220 | serkin_6 | 1 | 186 | 5.0E-33 |
| 4 | g10168.t5 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 1 | 210 | 6.74E-54 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
