General information for g10185.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Ubiquitin-like modifier-activating enzyme ATG7.
Parent gene
- The parent gene g10185 is located on chr_1: 8152071..8153248 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10185 | g10185.t1 | TSS | g10185.t1 | 8150192 | 8150192 |
| chr_1 | g10185 | g10185.t1 | isoform | g10185.t1 | 8150246 | 8152085 |
| chr_1 | g10185 | g10185.t1 | exon | g10185.t1.exon1 | 8150246 | 8150632 |
| chr_1 | g10185 | g10185.t1 | cds | g10185.t1.CDS1 | 8150246 | 8150632 |
| chr_1 | g10185 | g10185.t1 | exon | g10185.t1.exon2 | 8150689 | 8151738 |
| chr_1 | g10185 | g10185.t1 | cds | g10185.t1.CDS2 | 8150689 | 8151738 |
| chr_1 | g10185 | g10185.t1 | exon | g10185.t1.exon3 | 8151832 | 8152008 |
| chr_1 | g10185 | g10185.t1 | cds | g10185.t1.CDS3 | 8151832 | 8152008 |
| chr_1 | g10185 | g10185.t1 | exon | g10185.t1.exon4 | 8152071 | 8152085 |
| chr_1 | g10185 | g10185.t1 | cds | g10185.t1.CDS4 | 8152071 | 8152085 |
| chr_1 | g10185 | g10185.t1 | TTS | g10185.t1 | NA | NA |
Sequences
>g10185.t1 Gene=g10185 Length=1629
ATGTCAGAGAAAAAGGTGTTTCAATATGTACAATTCAAATCTCTTGTTCATCATGATTTT
TGGCATAAATTAAGCGATATTAAGCTTGATATAGAGAAATTAAATGAAAGTGATAAAACA
ATATTTGGAACTTTTACCAATTTAAATGCGAAAAATTGCCTTCTTGAACTTGATTGTACT
TCATTTAACTCTAATTTTAAAACTGCAAAAAATAATTTTTATTGTAAAGGAACTCTTAAA
AATCTCAATACAATAGAATCTTTTAAAAACTTTAACAGAAATGAATTGCTTAAAAAAGAA
GGTGAAAATTTATTAAGAATAATTGAAAATGGAAGTGCATGTAAAAATCCGAGCGAACTT
ATAAGTTTTATTGTTTTGACTTATGCGGATTTGAAAAAGTACAACTTTCATTACAGTTTT
GCTTTTACTGCCAGCATCGAACCACTAATTTATGAAGTATCTCCTTCTCAAAATATAACG
GATGAATTTTCTGAGAATGATATTGAAAACTTTAGTAGCAGCTATCATTTACTTGATCAG
CAACAAGCAGCATTTTTCATAGCTACAAAACACTTAGATATTATTTTGTTACAAAATGCA
CTTGATGTTAATCAACGAGATATGAATTTAAAAGATCATAATCTTGATTCTACTTATTTT
TGTTTTTCTGACCCGAGTGAGTTTCCTTACGCAGCTTGGATTTTAAGAAATTTTATTCTA
CTTCTTGTTAAACTATGTCCAATTTTACATGGAAAATCAATTAAAATATTATCTGTTCGT
CGTGATGAAAAGAGCTCACTTTTATTGAGCAAACTTTTTTTCATACAGCTACCAAATAAA
ATAGATTTAGATCCAATCAATATGAAATGGACAGGATGGGAAAGAAATGATCAGGGAAAA
CTTTTACCAAAATTAGCAAACATGAGCAATTCAATGGATCCTATTAAAATTGCAGAACAT
TTCTCAATGCTAAATTTGAAACTAATGAAATGGCGGCTTTTACCTAATTTAAATTTGGAT
GTTATTAAAAAACAAAAATGTTTGCTTTTTGGAGCAGGAACTTTAGGTTGTGCAATTGCA
CGATCACTTCTTAGCTGGGGTGTTGAAAATATAACGTTTATTGATTATGGAAATGTTAGT
CATTCCAATCCAGTAAGGCAATCATTATTCACACATTCAGATGCGATGCAAAATAAATTT
AAAGCAACAGCTGCATCAGAGAGATTAATTGAGATTTTACCAAGCGTTAAAACTAGTGGA
CATGTCTTGCAAATACCAATGCCTGGTCATCAAGTTGGTGAATCGATGAGAGATAAAACA
ATAGAAAACATTGAGAATATTATAAAATTGATACAAGAACATGATGTTCTGTTTTTGCTC
ACAGACTCTCGTGAAAGTCGATGGCTTCCAACAATGTTGGGTGTGTATTATGAAAAAACT
GTGATAACATCTGCTTTGGGTTTTGACAGTTATTTAGTAATGCGACATGGAGCTAAAGAA
AAAGAAACTTTTCAAATGACAGGTGAAAAAATTGAAGAAATTCCTGGACTGAAATGTATT
CCAGGAAATAAATTAGGATGTTACTTCTGCAACGATGTAACTGCACCAGGAAATTATTAC
CCATATTAA
>g10185.t1 Gene=g10185 Length=542
MSEKKVFQYVQFKSLVHHDFWHKLSDIKLDIEKLNESDKTIFGTFTNLNAKNCLLELDCT
SFNSNFKTAKNNFYCKGTLKNLNTIESFKNFNRNELLKKEGENLLRIIENGSACKNPSEL
ISFIVLTYADLKKYNFHYSFAFTASIEPLIYEVSPSQNITDEFSENDIENFSSSYHLLDQ
QQAAFFIATKHLDIILLQNALDVNQRDMNLKDHNLDSTYFCFSDPSEFPYAAWILRNFIL
LLVKLCPILHGKSIKILSVRRDEKSSLLLSKLFFIQLPNKIDLDPINMKWTGWERNDQGK
LLPKLANMSNSMDPIKIAEHFSMLNLKLMKWRLLPNLNLDVIKKQKCLLFGAGTLGCAIA
RSLLSWGVENITFIDYGNVSHSNPVRQSLFTHSDAMQNKFKATAASERLIEILPSVKTSG
HVLQIPMPGHQVGESMRDKTIENIENIIKLIQEHDVLFLLTDSRESRWLPTMLGVYYEKT
VITSALGFDSYLVMRHGAKEKETFQMTGEKIEEIPGLKCIPGNKLGCYFCNDVTAPGNYY
PY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g10185.t1 | Gene3D | G3DSA:3.40.140.100 | - | 8 | 283 | 0 |
| 6 | g10185.t1 | Gene3D | G3DSA:3.40.140.70 | - | 12 | 308 | 0 |
| 7 | g10185.t1 | Gene3D | G3DSA:3.40.50.720 | - | 311 | 540 | 0 |
| 3 | g10185.t1 | PANTHER | PTHR10953 | UBIQUITIN-ACTIVATING ENZYME E1 | 8 | 538 | 0 |
| 4 | g10185.t1 | PANTHER | PTHR10953:SF3 | UBIQUITIN-LIKE MODIFIER-ACTIVATING ENZYME ATG7 | 8 | 538 | 0 |
| 2 | g10185.t1 | Pfam | PF16420 | Ubiquitin-like modifier-activating enzyme ATG7 N-terminus | 8 | 312 | 0 |
| 1 | g10185.t1 | Pfam | PF00899 | ThiF family | 337 | 533 | 0 |
| 5 | g10185.t1 | SUPERFAMILY | SSF69572 | Activating enzymes of the ubiquitin-like proteins | 333 | 537 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008641 | ubiquitin-like modifier activating enzyme activity | MF |
KEGG
Orthology
- This transcript has been annotated with K08337 (ubiquitin-like modifier-activating enzyme ATG7)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
