General information for g10230.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Arylsulfatase B.
Parent gene
- The parent gene g10230 is located on chr_1: 8389604..8391315 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10230 | g10230.t1 | TTS | g10230.t1 | 8389574 | 8389574 |
| chr_1 | g10230 | g10230.t1 | isoform | g10230.t1 | 8389604 | 8391315 |
| chr_1 | g10230 | g10230.t1 | exon | g10230.t1.exon1 | 8389604 | 8390349 |
| chr_1 | g10230 | g10230.t1 | cds | g10230.t1.CDS1 | 8389604 | 8390349 |
| chr_1 | g10230 | g10230.t1 | exon | g10230.t1.exon2 | 8390403 | 8390843 |
| chr_1 | g10230 | g10230.t1 | cds | g10230.t1.CDS2 | 8390403 | 8390843 |
| chr_1 | g10230 | g10230.t1 | exon | g10230.t1.exon3 | 8390901 | 8391041 |
| chr_1 | g10230 | g10230.t1 | cds | g10230.t1.CDS3 | 8390901 | 8391041 |
| chr_1 | g10230 | g10230.t1 | exon | g10230.t1.exon4 | 8391123 | 8391315 |
| chr_1 | g10230 | g10230.t1 | cds | g10230.t1.CDS4 | 8391123 | 8391315 |
| chr_1 | g10230 | g10230.t1 | TSS | g10230.t1 | 8391437 | 8391437 |
Sequences
>g10230.t1 Gene=g10230 Length=1521
ATGGCTGATGATCTTGGATTTAATGATGTGAGCTACCGTGGATCAAATGAAATGGGAACG
TATAATATAGATTCTTTAGCATATAACGGAATAATTCTAGACAACTTTCATGCACCACCC
TTATGTACTCCATCACGTTCTGCATTTATGACTGGAAAACATCCATATCGTCTTGGAATG
CAACACTTTGTTGTACCAAGTGACGAGCCATGGGGTCTAGGTACTAAAGAAAAAATTATG
CCACAATATTTTAAAGAGGCAGGATACATTACGCGTTTGATAGGAAAGTGGCATTTAGGA
TTTTATCAGAAGCAATATACTCCTACACAAAGAGGATTTGATTCATTCTTTGGATATTTA
GGGCCTTATATTGATTACTTTGACTTTACTTTGAAAATGTTTGATAGAAACTTCTCACGT
GGGTATGATATGAGAAATAATCTTGACGTTTTTAATACTACATTACCTCAATATGCGACT
GAATTGTTTACAAAAGAGGCTGTAAAAGTAATAACAAATCATGATAAGAAAAACCCTCTC
TTTTTAATGGTGAATCATTTAGCACCACATGCTGGCAATGAGGATTTTCCAATGCAAGCA
AAGAAAGAAGACATTGCAAGATTTAATTATATCAAAGATGAAACTAGAAGAATACTTGGT
GGTATGATTTACCAGCTTGATCAAAGTGTTGGTGATATTGTAAAAGCTTTAAGCGATGCA
AATATGCTAAAAGATACTATTATCGTATTTTATTCAGATAATGGAGGTCCAACAGTGGGA
TTACATTCTACAGCAGCTTCAAATTTCCCATTAAGATCACAGAAACAAACAGCGTTTGAA
GGTGGAATTCGAACAAATGCTTTTATTTATTCATCATCATTACCAAAATCAACCATAAGG
AGAGGATTGTTTGATGTTTCTGATTTACTGCCAACATTAAATACATTATCAGGAGCTAAT
TTCAAAATTCAGGGAAAAATTGATGGTTTAGATCAAAGTCTGACTTTAAAATATAATTTC
AAATCGCCACGTAATGAACTTTTGACAGTTGACGATGTTTTAGGATATAGTTCTTATATT
TTTTATGGTTTGAAAATTGTTAACGGATCAAGCACTAATGGAAAATCAGATGGATTTTTA
GGCTCAAATAATAACAGTGATTATGATATTAAGAACTATATTAAAAATGTAAGAAATTCT
CGTGTGTCTACATATTTGAAAAACTCCATGAGTGATTATGGGATTGAAAGACTACGTGAG
TCTATTAAAGTGCAATGCTCAAATTCTGTTCATAAAAATCCTTGCGATTTATTGAAAGCA
CCTTGTCTTTTCGACTTAAATAATGATCCATGCGAGGAGAATAATATTGCTGAAAAATAT
CCAATCATTTTTAAACCTTTATTTTCAAGATATAAAAATGCTTTAACATCCATTGTGCAA
ACACGTCGAAAACCATCTGATCCACAATGTGATCCTGCTAATTTCAATTTTACATGGAAT
TGGTGGCAGCAAGATTCATAA
>g10230.t1 Gene=g10230 Length=506
MADDLGFNDVSYRGSNEMGTYNIDSLAYNGIILDNFHAPPLCTPSRSAFMTGKHPYRLGM
QHFVVPSDEPWGLGTKEKIMPQYFKEAGYITRLIGKWHLGFYQKQYTPTQRGFDSFFGYL
GPYIDYFDFTLKMFDRNFSRGYDMRNNLDVFNTTLPQYATELFTKEAVKVITNHDKKNPL
FLMVNHLAPHAGNEDFPMQAKKEDIARFNYIKDETRRILGGMIYQLDQSVGDIVKALSDA
NMLKDTIIVFYSDNGGPTVGLHSTAASNFPLRSQKQTAFEGGIRTNAFIYSSSLPKSTIR
RGLFDVSDLLPTLNTLSGANFKIQGKIDGLDQSLTLKYNFKSPRNELLTVDDVLGYSSYI
FYGLKIVNGSSTNGKSDGFLGSNNNSDYDIKNYIKNVRNSRVSTYLKNSMSDYGIERLRE
SIKVQCSNSVHKNPCDLLKAPCLFDLNNDPCEENNIAEKYPIIFKPLFSRYKNALTSIVQ
TRRKPSDPQCDPANFNFTWNWWQQDS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g10230.t1 | CDD | cd16029 | 4-S | 1 | 369 | 1.60714E-158 |
| 7 | g10230.t1 | Gene3D | G3DSA:3.40.720.10 | Alkaline Phosphatase | 1 | 344 | 7.0E-122 |
| 8 | g10230.t1 | Gene3D | G3DSA:3.30.1120.10 | - | 345 | 472 | 7.0E-122 |
| 2 | g10230.t1 | PANTHER | PTHR10342 | ARYLSULFATASE | 1 | 505 | 1.9E-193 |
| 3 | g10230.t1 | PANTHER | PTHR10342:SF264 | MIP05773P | 1 | 505 | 1.9E-193 |
| 1 | g10230.t1 | Pfam | PF00884 | Sulfatase | 1 | 318 | 8.9E-58 |
| 5 | g10230.t1 | ProSitePatterns | PS00523 | Sulfatases signature 1. | 40 | 52 | - |
| 6 | g10230.t1 | ProSitePatterns | PS00149 | Sulfatases signature 2. | 88 | 98 | - |
| 4 | g10230.t1 | SUPERFAMILY | SSF53649 | Alkaline phosphatase-like | 1 | 502 | 4.51E-96 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008484 | sulfuric ester hydrolase activity | MF |
| GO:0003824 | catalytic activity | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
