General information for g10244.t6
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as UDP-glucuronosyltransferase 2C1 .
Parent gene
- The parent gene g10244 is located on chr_1: 8514299..8515578 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10244 | g10244.t6 | isoform | g10244.t6 | 8513780 | 8515578 |
| chr_1 | g10244 | g10244.t6 | exon | g10244.t6.exon1 | 8513780 | 8514230 |
| chr_1 | g10244 | g10244.t6 | cds | g10244.t6.CDS1 | 8513780 | 8514230 |
| chr_1 | g10244 | g10244.t6 | exon | g10244.t6.exon2 | 8514287 | 8514874 |
| chr_1 | g10244 | g10244.t6 | cds | g10244.t6.CDS2 | 8514287 | 8514874 |
| chr_1 | g10244 | g10244.t6 | exon | g10244.t6.exon3 | 8514935 | 8515578 |
| chr_1 | g10244 | g10244.t6 | cds | g10244.t6.CDS3 | 8514935 | 8515155 |
| chr_1 | g10244 | g10244.t6 | TSS | g10244.t6 | NA | NA |
| chr_1 | g10244 | g10244.t6 | TTS | g10244.t6 | NA | NA |
Sequences
>g10244.t6 Gene=g10244 Length=1683
ATGAAGGTTTCTAGTGGAATTTTCATTTTATTTTTGAATTTATTAATAATTAATTATGGT
AGCAGTTTAAAAGTTTTAGGAATACTACCATTTTTTAGTAAATCGCATTTCGCTATCGGT
AGTTCAATTATCAATAGTTTACATTCAGCTGGACATAATATTACAGTAAAAGTTAAAAAA
AATACTTAGGGGCTATTAATATTAGTTATTTAAATACTTTAGGTCATATCACCTTTTCCT
CAGAGTAATTACTTCAAAGAGAGATATCGTGATGTTGACATTTCTGATTTATTGACGGAA
TATGAAAAAGGTTCATAAAATTTCATAATCGTTACAATCGATTGATATTTGATAAGAAAA
TTTTTCTTTAAAGATAATAAAGCTGTAAACCCGTTTGAATTGGTAAACATACCAAAACCT
CTTATGATGTTAATGCTTTATCAATTTGGTGCAATGGCAGTTGATTTTGTGATGACACAT
AAAAGTGTAAAAGAGTTGATGGACAGTAATGAAATGTTTGATGTGTGCATATTAGAAACA
TTTAATGCTGATGCATTTGTTGGATTTTCTGATTATTTTAATTGCACTTTAATTTCATAC
ACAACATTTGGAGCAGTCAAATGGATAGATGCAATGACAGGAAATGAATCACCTTCATCA
TATGTTCCTCATCCATTTTTGGATTATACTGATAAAATGACATTTACAGAACGATTATGG
AATAAGTTTTATAATATTTTGGAAAATTTATTATTTAATCTCTATCATTTATCTAAGCAG
AGATCATTATATAATAAGTATTTTCCTAATGCAAAAAAGTCATTCGATGAAATGTTTAAA
GGTTCTGCGATAATTTTTCAAAATTCTCATGTGACTTCATCCTTTCCTCGTCCTTATTTA
CCGAATATGATAGATATTTGTGGCATTCATGTGAAACCAGCAAAACTTTTACCCAATGAT
CTTCAAGAATTTATTGATTCAGCTGAAGATGGTGTGATCATTTTCACTATGGGTTCTTTT
ATCAATAGTAAAGATTTTCCAATAGAAAAACGTGAAGCTATAGTAAAGACTTTTGGTAAA
TTGAAACAGAAAATAATTTGGAAATATGAAAATGACACATTGCCAGACAATCCGGGTAAC
ATAAAAATCAGCTCATGGCTTCCACAGCGAGATTTGATTGCTCATAAAAATGTAAAGTTA
TTCATAACACATGGCGGACTCTTGGGCACAACTGAAGCTTTAACTGAAGGTTTGCCTGTT
CTAGGAATCCCTATATTCGGAGATCAAAAAATGAACATGGTAAAAGCAGAAGCTCGAGGA
TATGGTTTGCATGTGGCTTACGATGAACTTAATGAAGAAACTTTTAGTAAAGCTCTTAAC
GAAATCCTATCTAATCCAAAATATAAGAAAAATGCAGAAATCATTTCAAAAAGATTCATT
GATCGTCCGATGACACCGCAAGAAACAGTTGTTTATTGGACAGAATATGCTGTTAGACAT
GATGGCGCTAAACATTTAAGAGCATCTGGTAATGATTTAAATTTCATTCAATTTCATTCA
ATTGATGTATACTTAGTTCTTTTTGTTATTTTTGTTTTTATGTTATCCATAACATTTACT
ATTACAAAATTGCTATTGAAAAAGCTATTTTGTAAATCTGATGCAAAACAAAAGAAAAAT
TGA
>g10244.t6 Gene=g10244 Length=419
MMLMLYQFGAMAVDFVMTHKSVKELMDSNEMFDVCILETFNADAFVGFSDYFNCTLISYT
TFGAVKWIDAMTGNESPSSYVPHPFLDYTDKMTFTERLWNKFYNILENLLFNLYHLSKQR
SLYNKYFPNAKKSFDEMFKGSAIIFQNSHVTSSFPRPYLPNMIDICGIHVKPAKLLPNDL
QEFIDSAEDGVIIFTMGSFINSKDFPIEKREAIVKTFGKLKQKIIWKYENDTLPDNPGNI
KISSWLPQRDLIAHKNVKLFITHGGLLGTTEALTEGLPVLGIPIFGDQKMNMVKAEARGY
GLHVAYDELNEETFSKALNEILSNPKYKKNAEIISKRFIDRPMTPQETVVYWTEYAVRHD
GAKHLRASGNDLNFIQFHSIDVYLVLFVIFVFMLSITFTITKLLLKKLFCKSDAKQKKN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g10244.t6 | CDD | cd03784 | GT1_Gtf-like | 1 | 352 | 6.32488E-53 |
| 5 | g10244.t6 | Gene3D | G3DSA:3.40.50.2000 | Glycogen Phosphorylase B; | 171 | 339 | 1.6E-43 |
| 2 | g10244.t6 | PANTHER | PTHR48043 | EG:EG0003.4 PROTEIN-RELATED | 6 | 405 | 6.9E-118 |
| 3 | g10244.t6 | PANTHER | PTHR48043:SF59 | UDP-GLUCURONOSYLTRANSFERASE | 6 | 405 | 6.9E-118 |
| 1 | g10244.t6 | Pfam | PF00201 | UDP-glucoronosyl and UDP-glucosyl transferase | 21 | 408 | 1.9E-85 |
| 8 | g10244.t6 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 18 | - |
| 9 | g10244.t6 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 2 | - |
| 10 | g10244.t6 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 3 | 13 | - |
| 12 | g10244.t6 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 14 | 18 | - |
| 7 | g10244.t6 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 19 | 381 | - |
| 11 | g10244.t6 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 382 | 405 | - |
| 6 | g10244.t6 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 406 | 419 | - |
| 15 | g10244.t6 | ProSitePatterns | PS00375 | UDP-glycosyltransferases signature. | 245 | 288 | - |
| 4 | g10244.t6 | SUPERFAMILY | SSF53756 | UDP-Glycosyltransferase/glycogen phosphorylase | 8 | 365 | 2.79E-88 |
| 14 | g10244.t6 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 383 | 405 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008194 | UDP-glycosyltransferase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K00699 (glucuronosyltransferase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
