General information for g10281.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Actin-related protein 2/3 complex subunit 3.
Parent gene
- The parent gene g10281 is located on chr_1: 8621630..8622328 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10281 | g10281.t1 | TTS | g10281.t1 | 8621541 | 8621541 |
| chr_1 | g10281 | g10281.t1 | isoform | g10281.t1 | 8621630 | 8622328 |
| chr_1 | g10281 | g10281.t1 | exon | g10281.t1.exon1 | 8621630 | 8621781 |
| chr_1 | g10281 | g10281.t1 | cds | g10281.t1.CDS1 | 8621630 | 8621781 |
| chr_1 | g10281 | g10281.t1 | exon | g10281.t1.exon2 | 8621847 | 8622219 |
| chr_1 | g10281 | g10281.t1 | cds | g10281.t1.CDS2 | 8621847 | 8622219 |
| chr_1 | g10281 | g10281.t1 | exon | g10281.t1.exon3 | 8622323 | 8622328 |
| chr_1 | g10281 | g10281.t1 | cds | g10281.t1.CDS3 | 8622323 | 8622328 |
| chr_1 | g10281 | g10281.t1 | TSS | g10281.t1 | 8622449 | 8622449 |
Sequences
>g10281.t1 Gene=g10281 Length=531
ATGCCGGCTTATCACTCGCAAATTAAGGACTATGACAGGTCTATAGCTAATATGGCATTA
CTTCCTTTGAGAACACAATTTAGAGGACCAGCACCAACTGGTGCAAATATTGAGCAAGAT
GTCATAGATGAAGCAATTTATTACTTTAAAGCCAACATTTTCTTCAGAACATACGAAGTG
AAATCAGAAATTGATAGAGTTCTTATCTATGTTACTCTTTACATACCAGAATGTCTCAAA
AAGCTGCAAAGATGCGCAAACAAAAATCAAGGAATGCAAGAAATGTATACATTGGCAATA
AGCAAATTTGACATTCCAGGGGAGGCTGGATTTCCTCTCAATTCAGTTTATGCAAAACCT
TCAACACCAGCAGAGGGTGATTTAATGCGTCAATATTTACAACAACTTCGACAAGAGACT
GGTAATAGAATTTGTGAAAAAGTGTTCAATACAGAAGATGGAAAGCCAAGTAAATGGTGG
ATGTGTTTTTCTAAGAAGAAGTTTATGGAAAAGAGTTTGGGTGTGTACTAA
>g10281.t1 Gene=g10281 Length=176
MPAYHSQIKDYDRSIANMALLPLRTQFRGPAPTGANIEQDVIDEAIYYFKANIFFRTYEV
KSEIDRVLIYVTLYIPECLKKLQRCANKNQGMQEMYTLAISKFDIPGEAGFPLNSVYAKP
STPAEGDLMRQYLQQLRQETGNRICEKVFNTEDGKPSKWWMCFSKKKFMEKSLGVY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g10281.t1 | Gene3D | G3DSA:1.10.1760.10 | Arp2/3 complex 21 kDa subunit ARPC3 | 1 | 175 | 0 |
| 2 | g10281.t1 | PANTHER | PTHR12391:SF1 | ACTIN-RELATED PROTEIN 2/3 COMPLEX SUBUNIT 3 | 1 | 173 | 0 |
| 3 | g10281.t1 | PANTHER | PTHR12391 | ARP2/3 COMPLEX 21 KD SUBUNIT | 1 | 173 | 0 |
| 6 | g10281.t1 | PIRSF | PIRSF016315 | p21-ARC | 1 | 173 | 0 |
| 1 | g10281.t1 | Pfam | PF04062 | ARP2/3 complex ARPC3 (21 kDa) subunit | 1 | 173 | 0 |
| 4 | g10281.t1 | SUPERFAMILY | SSF69060 | Arp2/3 complex 21 kDa subunit ARPC3 | 2 | 173 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0030833 | regulation of actin filament polymerization | BP |
| GO:0005856 | cytoskeleton | CC |
| GO:0005885 | Arp2/3 protein complex | CC |
| GO:0034314 | Arp2/3 complex-mediated actin nucleation | BP |
KEGG
Orthology
- This transcript has been annotated with K05756 (actin related protein 2/3 complex, subunit 3)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
