General information for g1030.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as E3 ubiquitin-protein ligase TRIP12.
Parent gene
- The parent gene g1030 is located on chr_3: 7670824..7675410 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_3 | g1030 | g1030.t1 | isoform | g1030.t1 | 7670824 | 7675410 |
| chr_3 | g1030 | g1030.t1 | exon | g1030.t1.exon1 | 7670824 | 7673745 |
| chr_3 | g1030 | g1030.t1 | cds | g1030.t1.CDS1 | 7670824 | 7673745 |
| chr_3 | g1030 | g1030.t1 | exon | g1030.t1.exon2 | 7673812 | 7675410 |
| chr_3 | g1030 | g1030.t1 | cds | g1030.t1.CDS2 | 7673812 | 7675410 |
| chr_3 | g1030 | g1030.t1 | TSS | g1030.t1 | NA | NA |
| chr_3 | g1030 | g1030.t1 | TTS | g1030.t1 | NA | NA |
Sequences
>g1030.t1 Gene=g1030 Length=4521
ATGAATCCAATCGGTTCATCAACTACTCAACAATTACTTCAAGGACTAAAAAGCAATGAA
GAAAGCCAGCAACTGCAAGCATTAATTGAAATTTGCACGATCCTTGTAATGGGCAATGAA
GAAACACTTGTTGGATTTCCCATCATTCAAACGATTCCTTCACTCATCAATTTGCTCCAA
AAGGAAGAAAATTTTGATTTGATGAATCATGCATGTCGTGCACTGACTTACATGCTTGAA
GCACTTCCGCGTTCATCAATTTTGATCATTGACGCAATTCCTGCTTTGCTTTGGAAACTT
CAAGAAATTCAATGCATTGATGTAGCTGAACAAAGTTTAATAGCATTGGAAATTTTATCA
AGGCGCCATTTTAAGGCAATTTTATATGGAAACGGAATTTCAATTTGTCTTTCATTTTTG
GATTTCTTTTCGGTGACTTCACAAAATGCAGCACTGACAATAGTTTCAAATTGCTGTCTA
AATTTAAAAGTTCAAGAATTCAATTTTTTCAGAGGCTCAATTTCACTTTTAACTCAAATT
TTATCTAAAAATGATAACAAAAATTTGGAACAAGTTTGCAATATTTTTTGTCGTTTGACT
GAAGGATTTAAAGATAATTCTGTGATTTTACAAGAAATTGGTAGCACCGAATTGATGAAA
AATTGTCAAAAATTGCTTGTTGCTAGTCCATCAGTTTTGAATAATGGAACTTTTACAAAT
GTTATAAAAATGATGAGCAATTTATGTGCAAGCTGTCCAGATTTGGTTAAGTTTTTGCTT
GAAAATGACATTGTTTCGAATTTGCTATTTTTATTGACGAATCCAACAAATATTTCTTCA
AAAATTGAGCTTGTTCAACGAAATTCTACAGAGTTAAATGAAATAATGCGTTTAATTGTT
GAATTATTACCGAAGCTACCAAATGAAGGAATTTTAGAAGCTGAAAAAGATGATTTTATT
GCAACAACATCTGATGAAAACAGAAGTTCCATAGAAAATTTCATAAAACTTTTGATCTCT
GTTCTTTTTGAAGTCTACAGTTTTTCGTCGACTCCATTTGTACGTTACAAATGTCTACAA
GCACTTTTACGAATGATTCATTTCGCCAATGCTGATTTATTAAAAGAAGTTCTGAATAGA
CAATTTGTTTCTTCTAATATTGCTGGAATGATTGCTTCAAATGACAACAAAATTATTATT
GAAGCTTTGAAGATGGCTGAGATTTTAATGCAGAAGCTTCCAGATGTTTTTGGTAATTAT
TTCCAACGAGAAGGTGTTATGCATTATATTCAAAAACTTGTTGATTCTATTGAATTGAAA
TCACAAAAAGATAATTCAACTACAGAGGAAAATTTTGAGTCTGGTAATTTGAAATTGGAA
AATTCAAGTCGTAAGCTAAATTCCCAAACTTCTATTGAGTCAAAGGATAAAGAAATAGTA
AATATTGATTCTAAGGAAAAAGAAAAAATGGTTAGTGAATCAAAGAAAGAAGAAGTAACA
TTAATTGAGCCAAAAAATCTAGAAAACTCATCAATTGAGTTAAAAGTAACAAAACTTGAA
ACAGAAGATCAAAAAGTTTCTATTTCTGAATCAAAAAATAATGAAGTAACATCAATTGAG
CCAACAAATCAATCAGAATCTGCAATTGAAGATTTAAATTCTGATGATGATTTTGAAGAT
GATTCAATGAGTGAAAACACCATTTATGATTCATTTAACTCATCTTCATCAAGTTCTTCA
TCATATGAAAGTGTTAAAAATGCTGATGAAATTCCTATGCTAAATACTTCAAGAATCAAT
CAAAATGCATCGAAAATCAGTCAAATTGAAATTGAAAATGAAAATTCAAGACAATGGATC
AAAAATAAAGCAATTTCTTTCATCAATCGTTACTCAAATGACTGCATAAACTCAAATCTT
ACAATTATGTCAAGTTTGGCAGCTGCAATTAAGAAACTTGATGGATCGCATGATGATTGC
ATAAATGGCATGGAGGAATTGAAAAATATTTTACTAGAAAGCGACATTTCATCATTTGAA
TTCAATCAAAGTGGATTGATCAACGCAATGTTGAATTTCATGACAAAAGAAGAAGGAAAA
ATTTTTCGTGATGATCGATTAAGATTGTTTTTGAATATTTTTACAAATTTACCAATTGAT
ACAAATTACAATCATGAAATTTCAATTAATCCAACTGCATTTAGCTCACTTGTCTCAAAA
TTAAATTTATGTTTGACCCGATTGGAAGAATTTACCATAAAAGTTTATGATTATCGTTCA
AATGTGAATCCAATTAAATTTTTTACAACTCATCAATTAAATGTCAATATTCAAAAACAT
CCAGAATGCACAAATGTTGGTAAATTCAAAGATGGAGTAGTGAAAATTGCGCCATTAGCT
CAAATTGAATTATTTGAAAAATATCTTGAATCTGAAAATGAAGAAAATTTAGAACCAAGA
ATAATTGCAGATGGAAGAAAAAGAAAATTTCAATTTTTCATTAATAATCAACTTGTGGAA
AATTCGATGACAATTTATCAAGCAATTAAGGAAAATTCACCTGCAGTAAATGGTGAATCA
AGGACAGAAAATTGCATAGGAAGTGTAAACATTTGGCTACAACAGCATACAATCCTTTAT
AAAGTAATTGAAGAGAAATTTGAAGCTCAATCAACAAGTTGTTCAGAAGCTAAGCCTGAT
CTAACCTCAGCAGAATTAAGCACTAGAAATTTAGTTCCAACGATTATTTCACCTTTAAAC
AAATATTTAGACACAAAATTTCTTGAAACTATTAAAGATTCATCAGTTGGAGTTTTAACT
TTACTAAGAGTTCTTAATGGTCTTAATAGATATTGGTCTTCTCTTTATTCTTCTCTAAAA
CAAACTCAAATCATTGATCAAGCTGAATTTATTAATTCAAAGATTTCGACAAAAGTCATC
CGACAACTTCAAGATCCATTAATAATCATGACTGGAAGTTTACCAAATTGGTTAAAAGAC
CTTGCAATCTCATGTCCATTTTTATTCCCATTTGAAACTCGACATCTTCTATTTTATGTC
ACTTCATTTGATCGAGATCGTGCACTGCAACGTGTGATTGACACAACACCAGATTTGATT
TCTAAACGTGAAATTCTTCCAAGATTAAATCGACAGAAGTGCGAAATTTCTCGTAAAAAC
ATTTTGAAACACGCTGAATTTATTATGAAAAAATTCGGAAATTCAAAATCTTTGCTTGAA
ATTCAATATGAAAACGAAGTTGGAACAGGATTGGGTCCGACATTGGAATTTTATGCTTTA
GTTTCAAATGAACTACAGAGAAGTGATTTAAATTTATGGAATGATGCTGAAAATAGTTAT
AGAAATCAAGAAATTAAGGAAAATTTTGCAATAATTCCTGCAATTTTGGTTTATGATGAA
AATTCACATTTAATTTTTGAAGATTTGATGATAAAAATTGACGGAATTGACAGAGATGAA
AAACTTGAAATTAAAAAGATTGATAAAATTAATCCAGAAGACTCGAGACTCAAACAGCAT
AGAAATATTCAATATGTAAATTCACCTAATGGATTATTCCCAGTTGCTTTAAACAAGGCT
ACAAGATTATCAAAAATCAAATCAAGATTCAATTTCCTAGGCAAATTTATGGCTAAGTCA
GTTCTAGACAGTCGAATGATTGATCTACCACTTTCAATGCCATTCTATCGCTGGATTTTA
AATGAACAAATTTCATTTGACTTATTTGATTTAGAAAAAGTCGCTCCAGAAGTTCACAAT
GTTTTGTTGCGTTTAAATGAAATTGTAAAGCAACGAGAAATCATTCAAGAAAATTCTTCA
TTAAATAACCAAGAAAAAGCAGCAAAAATTGAAGCTCTAAATCTTGATGGATGTCAAATT
TCTGACCTCTCATTAAATTTTGTGCTTCCTGGTCATCCAAACATTGAATTGCTTGAAAAT
GGTCAAAATATTCCTGTGACAATTTACAATCTTCATGAATACATTTCATTAGTTTCTCAT
TGGTTTCTTGTTAAAGGTGTGACTGAACAATTCGAATCATTCAAAGAAGGTTTCAATTCA
ATTTTTTCAATTGAAACTTTAAAACTTTTCTATCCTGAAGAATTAGAAAATGTCTTTTGT
GGTTCAGGAAATTTTCAAAAATGGAATACGAAAATGTTGGCTGAATGTTGCAGAACTGAT
CATGGATTTACACAAGAATCGATTGTGATTCAAAATTTTTATGATATTTTAAGTCAATTC
AATCGTGAAGAGCAAAGGTCATTTTTGCAATTCATCACTGGAACACCAAAATTGCCAGTT
GGTGGCTTTAAATCTTTGATACCGCCATTGACGATTGTTGCGAAGAAAATTGATGAAAAT
CAAAATCCTGATGATTTTCTACCTTCTGTTATGACTTGTGTCAATTATTTGAAACTTCCA
GAATATTCAAATCGTGAAATTATGAAGGAAAAATTAAAAATTGCTGCAAATGAAGGAAGT
TTGAGTTTTCATCTTTCTTAA
>g1030.t1 Gene=g1030 Length=1506
MNPIGSSTTQQLLQGLKSNEESQQLQALIEICTILVMGNEETLVGFPIIQTIPSLINLLQ
KEENFDLMNHACRALTYMLEALPRSSILIIDAIPALLWKLQEIQCIDVAEQSLIALEILS
RRHFKAILYGNGISICLSFLDFFSVTSQNAALTIVSNCCLNLKVQEFNFFRGSISLLTQI
LSKNDNKNLEQVCNIFCRLTEGFKDNSVILQEIGSTELMKNCQKLLVASPSVLNNGTFTN
VIKMMSNLCASCPDLVKFLLENDIVSNLLFLLTNPTNISSKIELVQRNSTELNEIMRLIV
ELLPKLPNEGILEAEKDDFIATTSDENRSSIENFIKLLISVLFEVYSFSSTPFVRYKCLQ
ALLRMIHFANADLLKEVLNRQFVSSNIAGMIASNDNKIIIEALKMAEILMQKLPDVFGNY
FQREGVMHYIQKLVDSIELKSQKDNSTTEENFESGNLKLENSSRKLNSQTSIESKDKEIV
NIDSKEKEKMVSESKKEEVTLIEPKNLENSSIELKVTKLETEDQKVSISESKNNEVTSIE
PTNQSESAIEDLNSDDDFEDDSMSENTIYDSFNSSSSSSSSYESVKNADEIPMLNTSRIN
QNASKISQIEIENENSRQWIKNKAISFINRYSNDCINSNLTIMSSLAAAIKKLDGSHDDC
INGMEELKNILLESDISSFEFNQSGLINAMLNFMTKEEGKIFRDDRLRLFLNIFTNLPID
TNYNHEISINPTAFSSLVSKLNLCLTRLEEFTIKVYDYRSNVNPIKFFTTHQLNVNIQKH
PECTNVGKFKDGVVKIAPLAQIELFEKYLESENEENLEPRIIADGRKRKFQFFINNQLVE
NSMTIYQAIKENSPAVNGESRTENCIGSVNIWLQQHTILYKVIEEKFEAQSTSCSEAKPD
LTSAELSTRNLVPTIISPLNKYLDTKFLETIKDSSVGVLTLLRVLNGLNRYWSSLYSSLK
QTQIIDQAEFINSKISTKVIRQLQDPLIIMTGSLPNWLKDLAISCPFLFPFETRHLLFYV
TSFDRDRALQRVIDTTPDLISKREILPRLNRQKCEISRKNILKHAEFIMKKFGNSKSLLE
IQYENEVGTGLGPTLEFYALVSNELQRSDLNLWNDAENSYRNQEIKENFAIIPAILVYDE
NSHLIFEDLMIKIDGIDRDEKLEIKKIDKINPEDSRLKQHRNIQYVNSPNGLFPVALNKA
TRLSKIKSRFNFLGKFMAKSVLDSRMIDLPLSMPFYRWILNEQISFDLFDLEKVAPEVHN
VLLRLNEIVKQREIIQENSSLNNQEKAAKIEALNLDGCQISDLSLNFVLPGHPNIELLEN
GQNIPVTIYNLHEYISLVSHWFLVKGVTEQFESFKEGFNSIFSIETLKLFYPEELENVFC
GSGNFQKWNTKMLAECCRTDHGFTQESIVIQNFYDILSQFNREEQRSFLQFITGTPKLPV
GGFKSLIPPLTIVAKKIDENQNPDDFLPSVMTCVNYLKLPEYSNREIMKEKLKIAANEGS
LSFHLS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g1030.t1 | Gene3D | G3DSA:1.25.10.10 | - | 7 | 306 | 4.6E-24 |
| 11 | g1030.t1 | Gene3D | G3DSA:3.90.1750.10 | Hect | 1027 | 1144 | 3.6E-5 |
| 10 | g1030.t1 | Gene3D | G3DSA:3.90.1750.10 | Hect | 1175 | 1273 | 4.3E-7 |
| 12 | g1030.t1 | Gene3D | G3DSA:3.30.2410.10 | Hect | 1385 | 1505 | 5.9E-30 |
| 7 | g1030.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 521 | 549 | - |
| 8 | g1030.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 530 | 549 | - |
| 2 | g1030.t1 | PANTHER | PTHR45670 | E3 UBIQUITIN-PROTEIN LIGASE TRIP12 | 8 | 1506 | 0.0 |
| 3 | g1030.t1 | PANTHER | PTHR45670:SF1 | E3 UBIQUITIN-PROTEIN LIGASE TRIP12 | 8 | 1506 | 0.0 |
| 1 | g1030.t1 | Pfam | PF00632 | HECT-domain (ubiquitin-transferase) | 1141 | 1506 | 1.3E-79 |
| 13 | g1030.t1 | ProSiteProfiles | PS50237 | HECT domain profile. | 1210 | 1506 | 65.248 |
| 6 | g1030.t1 | SMART | SM00119 | hect_3 | 1063 | 1506 | 2.9E-88 |
| 4 | g1030.t1 | SUPERFAMILY | SSF48371 | ARM repeat | 8 | 436 | 8.64E-37 |
| 5 | g1030.t1 | SUPERFAMILY | SSF56204 | Hect, E3 ligase catalytic domain | 1044 | 1499 | 4.19E-94 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004842 | ubiquitin-protein transferase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K10590 (E3 ubiquitin-protein ligase TRIP12)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed