Gene loci information

Transcript annotation

  • This transcript has been annotated as E3 ubiquitin-protein ligase TRIP12.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g1031 g1031.t1 isoform g1031.t1 7683212 7684485
chr_3 g1031 g1031.t1 exon g1031.t1.exon1 7683212 7683373
chr_3 g1031 g1031.t1 cds g1031.t1.CDS1 7683212 7683373
chr_3 g1031 g1031.t1 exon g1031.t1.exon2 7683820 7684187
chr_3 g1031 g1031.t1 cds g1031.t1.CDS2 7683820 7684187
chr_3 g1031 g1031.t1 exon g1031.t1.exon3 7684242 7684485
chr_3 g1031 g1031.t1 cds g1031.t1.CDS3 7684242 7684485
chr_3 g1031 g1031.t1 TSS g1031.t1 NA NA
chr_3 g1031 g1031.t1 TTS g1031.t1 NA NA

Sequences

>g1031.t1 Gene=g1031 Length=774
ATGAAAACGAAGTTGGAAACAGGATTGGGTCCGACATTGGAATTTTATGCTTTAGTTTCA
AATGAACTACAGAGAAGTGATTTAAATTTATGGAATGATGCTGAAAATAGTTATAGAAAT
CAAGAAATTAAGGAAACTTTTGCAATAGTTCCTGCAATTTTGAAAAGCAGCAAAAATGAA
GCTCTAAATCTTGATGGATGTCAAATTTCTGACCTCTCATTAAATTTTGTGCTTCCTGGT
CATCCAAACATTGAATTGCTTGAAAATGGTCAAAATATTCCTGTGACAATTTACAATCTT
CATGAATACATTTCATTAGTTTCTCATTGGTTTCTTGTCAAAGGCGTGACTGAACAATTC
GAATCATTCAAAGAAGGTTTCAATTCAATTTTTTCAATTGAAACTTTAAAACTTTTCTAT
CCTGAAGAATTAGAAAATGTCTTTTTGGTTCAGGAAATTTTCAAAAATGGAATACGAAAA
TGTTGGCTGAATGTTGCAGAACTGATCATGGATTTACACAAGAATCGATTGTCATTTTTG
CAATTCATCACTGGAACACCAAAATTGCCAGTTGGTGGCTTTAAATCTTTGACACCGCCA
TTTACGATTGTTGCGAAGAAAATTGATGAAAATCAAAATCCTGATGATTTTCTACCTTCT
GTTATGACTTGTGTCAATTATTTGAAACTTCCAGAATATTCAAATCGTGAAATTATGAAG
GAAAAATTAAAAATTGCTGCAAATGAAGGAAGTTTGAGTTTTCATCTTTCTTAA

>g1031.t1 Gene=g1031 Length=257
MKTKLETGLGPTLEFYALVSNELQRSDLNLWNDAENSYRNQEIKETFAIVPAILKSSKNE
ALNLDGCQISDLSLNFVLPGHPNIELLENGQNIPVTIYNLHEYISLVSHWFLVKGVTEQF
ESFKEGFNSIFSIETLKLFYPEELENVFLVQEIFKNGIRKCWLNVAELIMDLHKNRLSFL
QFITGTPKLPVGGFKSLTPPFTIVAKKIDENQNPDDFLPSVMTCVNYLKLPEYSNREIMK
EKLKIAANEGSLSFHLS

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g1031.t1 Gene3D G3DSA:3.30.2160.10 Hect 79 115 0.0000027
9 g1031.t1 Gene3D G3DSA:3.30.2410.10 Hect 152 257 0.0000000
2 g1031.t1 PANTHER PTHR45670 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 7 38 0.0000000
4 g1031.t1 PANTHER PTHR45670:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 7 38 0.0000000
3 g1031.t1 PANTHER PTHR45670 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 58 257 0.0000000
5 g1031.t1 PANTHER PTHR45670:SF1 E3 UBIQUITIN-PROTEIN LIGASE TRIP12 58 257 0.0000000
1 g1031.t1 Pfam PF00632 HECT-domain (ubiquitin-transferase) 59 257 0.0000000
10 g1031.t1 ProSiteProfiles PS50237 HECT domain profile. 85 257 35.7040000
7 g1031.t1 SMART SM00119 hect_3 1 257 0.0000000
6 g1031.t1 SUPERFAMILY SSF56204 Hect, E3 ligase catalytic domain 8 250 0.0000000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0004842 ubiquitin-protein transferase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed