General information for g10334.t41
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Protein disulfide-isomerase A3.
Parent gene
- The parent gene g10334 is located on chr_1: 8934649..8935590 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10334 | g10334.t41 | TTS | g10334.t41 | 8933125 | 8933125 |
| chr_1 | g10334 | g10334.t41 | isoform | g10334.t41 | 8934068 | 8935590 |
| chr_1 | g10334 | g10334.t41 | exon | g10334.t41.exon1 | 8934068 | 8934407 |
| chr_1 | g10334 | g10334.t41 | cds | g10334.t41.CDS1 | 8934068 | 8934407 |
| chr_1 | g10334 | g10334.t41 | exon | g10334.t41.exon2 | 8934468 | 8934696 |
| chr_1 | g10334 | g10334.t41 | cds | g10334.t41.CDS2 | 8934468 | 8934696 |
| chr_1 | g10334 | g10334.t41 | exon | g10334.t41.exon3 | 8934759 | 8934836 |
| chr_1 | g10334 | g10334.t41 | cds | g10334.t41.CDS3 | 8934759 | 8934836 |
| chr_1 | g10334 | g10334.t41 | exon | g10334.t41.exon4 | 8934917 | 8934967 |
| chr_1 | g10334 | g10334.t41 | cds | g10334.t41.CDS4 | 8934917 | 8934967 |
| chr_1 | g10334 | g10334.t41 | exon | g10334.t41.exon5 | 8935028 | 8935088 |
| chr_1 | g10334 | g10334.t41 | cds | g10334.t41.CDS5 | 8935028 | 8935088 |
| chr_1 | g10334 | g10334.t41 | exon | g10334.t41.exon6 | 8935459 | 8935590 |
| chr_1 | g10334 | g10334.t41 | cds | g10334.t41.CDS6 | 8935459 | 8935590 |
| chr_1 | g10334 | g10334.t41 | TSS | g10334.t41 | 8935652 | 8935652 |
Sequences
>g10334.t41 Gene=g10334 Length=891
ATGAAATTACTTGTTTTTCTGTCATTTTTGTTTGTTGCTGAGTTGGCTCTCTCGGCTGAG
AGTGATGTTCTTGAATTGACTGATTCTGATTTTGAAACTACAATCAAAGAATATCCAACA
GTGTTGGCAATGCTTAAACCAGAATATGCCAAAGCAGCAGAATTGATGAGAACTGATGAT
CCTCCAATTACTCTTGTCAAAGTTGATTGTACAGAAGGCGGCAAGGATACTTGCAGCAAA
TTCGGTGTTTCTGGATATCCCACTCTCAAAATTTTCAGAAACGGTGAAAATCCTCAGGAT
TATAATGGTCCACGTGAAGCAAGTGGTATTGTGAAATATATGAGAGCACAAGTTGGTCCA
TCATCAAAGGATCTTCTAACAGTTGAAGCATATGAAAAGTTCTTGGGTGTTCAAGAGGGT
GCCGTAGTTGGATTCTTTGAAAAAGAAACGGATTTGAAGACTGTTTTCTTAAAATATGCC
GATTTGCAACGTGAGAAACTTCGCTTTGCACATTCAAGTGATCCAGAAATTCTCAAGAAA
GTTGGCGAAACAAACGCTATTCTTCTTTATCGTGCACCACAATTGAGTAATAAGTTTGAA
CCATCTTTTGTTAAATTCACTGGAAAAGATTCAAGTGATCTTAAAGAATTTGTTAAGAAG
AACTTCCACGGTTTAGTTGGTGTACGTAGTCGTGATACTATTACTGATTTCAACAATCCA
TTGGTAACTGCATATTATGCTGTTGATTATATTAAAAATGCAAAAGGCACAAACTACTGG
CGCAATCGTGTACTTAAAGTTGCCAAAGAATGGGAAGGTAAAATCAATTTTGCTATTGCT
GCTAAAGATGAATTCCAACATGAATTGAATGAATATGGTTACGATTATGTC
>g10334.t41 Gene=g10334 Length=297
MKLLVFLSFLFVAELALSAESDVLELTDSDFETTIKEYPTVLAMLKPEYAKAAELMRTDD
PPITLVKVDCTEGGKDTCSKFGVSGYPTLKIFRNGENPQDYNGPREASGIVKYMRAQVGP
SSKDLLTVEAYEKFLGVQEGAVVGFFEKETDLKTVFLKYADLQREKLRFAHSSDPEILKK
VGETNAILLYRAPQLSNKFEPSFVKFTGKDSSDLKEFVKKNFHGLVGVRSRDTITDFNNP
LVTAYYAVDYIKNAKGTNYWRNRVLKVAKEWEGKINFAIAAKDEFQHELNEYGYDYV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 17 | g10334.t41 | CDD | cd02961 | PDI_a_family | 24 | 114 | 2.63068E-25 |
| 9 | g10334.t41 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 14 | 118 | 7.7E-22 |
| 11 | g10334.t41 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 119 | 228 | 1.1E-30 |
| 10 | g10334.t41 | Gene3D | G3DSA:3.40.30.10 | Glutaredoxin | 230 | 297 | 1.3E-22 |
| 3 | g10334.t41 | PANTHER | PTHR18929:SF45 | PROTEIN DISULFIDE-ISOMERASE | 11 | 291 | 3.3E-67 |
| 4 | g10334.t41 | PANTHER | PTHR18929 | PROTEIN DISULFIDE ISOMERASE | 11 | 291 | 3.3E-67 |
| 2 | g10334.t41 | Pfam | PF00085 | Thioredoxin | 44 | 115 | 7.5E-14 |
| 1 | g10334.t41 | Pfam | PF13848 | Thioredoxin-like domain | 147 | 295 | 7.3E-25 |
| 13 | g10334.t41 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 18 | - |
| 14 | g10334.t41 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 2 | - |
| 15 | g10334.t41 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 3 | 13 | - |
| 16 | g10334.t41 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 14 | 18 | - |
| 12 | g10334.t41 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 19 | 297 | - |
| 6 | g10334.t41 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 17 | 119 | 7.24E-22 |
| 5 | g10334.t41 | SUPERFAMILY | SSF52833 | Thioredoxin-like | 123 | 222 | 2.4E-12 |
| 8 | g10334.t41 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 18 | - |
| 18 | g10334.t41 | SignalP_GRAM_NEGATIVE | SignalP-noTM | SignalP-noTM | 1 | 18 | - |
| 7 | g10334.t41 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 18 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed