General information for g10362.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Neuroligin-4, Y-linked.
Parent gene
- The parent gene g10362 is located on chr_1: 9112395..9160197 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10362 | g10362.t1 | isoform | g10362.t1 | 9112395 | 9160197 |
| chr_1 | g10362 | g10362.t1 | exon | g10362.t1.exon1 | 9112395 | 9112543 |
| chr_1 | g10362 | g10362.t1 | cds | g10362.t1.CDS1 | 9112395 | 9112543 |
| chr_1 | g10362 | g10362.t1 | exon | g10362.t1.exon2 | 9114061 | 9114765 |
| chr_1 | g10362 | g10362.t1 | cds | g10362.t1.CDS2 | 9114061 | 9114765 |
| chr_1 | g10362 | g10362.t1 | exon | g10362.t1.exon3 | 9115380 | 9115622 |
| chr_1 | g10362 | g10362.t1 | cds | g10362.t1.CDS3 | 9115380 | 9115622 |
| chr_1 | g10362 | g10362.t1 | exon | g10362.t1.exon4 | 9116280 | 9116398 |
| chr_1 | g10362 | g10362.t1 | cds | g10362.t1.CDS4 | 9116280 | 9116398 |
| chr_1 | g10362 | g10362.t1 | exon | g10362.t1.exon5 | 9116535 | 9116901 |
| chr_1 | g10362 | g10362.t1 | cds | g10362.t1.CDS5 | 9116535 | 9116901 |
| chr_1 | g10362 | g10362.t1 | exon | g10362.t1.exon6 | 9116969 | 9117460 |
| chr_1 | g10362 | g10362.t1 | cds | g10362.t1.CDS6 | 9116969 | 9117460 |
| chr_1 | g10362 | g10362.t1 | exon | g10362.t1.exon7 | 9117516 | 9117710 |
| chr_1 | g10362 | g10362.t1 | cds | g10362.t1.CDS7 | 9117516 | 9117710 |
| chr_1 | g10362 | g10362.t1 | exon | g10362.t1.exon8 | 9117767 | 9117916 |
| chr_1 | g10362 | g10362.t1 | cds | g10362.t1.CDS8 | 9117767 | 9117916 |
| chr_1 | g10362 | g10362.t1 | exon | g10362.t1.exon9 | 9118014 | 9118231 |
| chr_1 | g10362 | g10362.t1 | cds | g10362.t1.CDS9 | 9118014 | 9118231 |
| chr_1 | g10362 | g10362.t1 | exon | g10362.t1.exon10 | 9159977 | 9160197 |
| chr_1 | g10362 | g10362.t1 | cds | g10362.t1.CDS10 | 9159977 | 9160197 |
| chr_1 | g10362 | g10362.t1 | TSS | g10362.t1 | NA | NA |
| chr_1 | g10362 | g10362.t1 | TTS | g10362.t1 | NA | NA |
Sequences
>g10362.t1 Gene=g10362 Length=2859
ATGCTTGCTGTCTGTCAACTACTTATAGTGCTCATACTTGATGTCACGTTAGCGGCTCAT
GTCGATATCTATAAAAATGCACGTCTCGGGACACGCATTGTGCAGACTCGTTTTGGTCGA
TTGCAAGGATTAGTTTTACCATTAGATAACTACAAATTTTTGAAGCCCGTTGAAGCGTTT
CTTGCAGTTCCATATGCAACACCGCCAACAAAAAGTAATCGTTTTGGTCCAACGAGAACG
CCCTCACCCTGGGATGGTGTACGAAAAACCAACAATTTTAGTGCCGTTTGCCCGCAACGA
TTGCCCGAAATACAAAACGAGGAAGAGGCACTAAAAAAGATGCCAAAGGGTCGTTTAGAA
TATTTAAAACGTTTACTGCCTTTTTTACAAAACCAATCTGAAGATTGTTTATATTTAAAC
GTCTTTTCGCCACTTCATGCGGCTGTTCAAGAGAAGAAACTTCCTGTGCTTGTGTTCATT
CATGGTGAATCATTCGAATGGAACTCGGGAAATCCTTATGACGGTTCCATTTTGGCGAGT
TATGCTGAAATCATTGTAGTTACACTGAATTACCGTTTAGGCATTTTAGGATTTTTAAAT
GCTAATCCGGCGCCACATATACGTGCTAGAGTGGCCAACTATGGTTTAATGGATCAGATG
GCAGCATTGCATTGGATTCAGCAGAATATTGAAAAGTTCGGTGGTAATCCATCGATGGTG
ACTCTTGCAGGACATGGAACTGGCGCTGCATGTATAGATTTTTTAATGTCATCACCATCA
ATGGTTCCAGGATTATTTCATCGAGCCATTCTTATGTCAGGTTCAGCCTATTCATCATGG
GCATTAGTAGAAGATCCAGTAATTTATGCAGTAAAATTAGCTAAAGAATTAAATTGCTCA
ATACCTGAAGATCTTATAAAAGATCACGAGTCAATTGTCGACTGTTTACGTGAGGTGCCT
TTAGAGGATCTCTATGCAGTTGACATTCAACCACCGAATTTTTTAAGTGCATTTGGTCCA
TCAGTTGATGGTGTAGTTATACGACCAGGTCGATCTAATCAAGACCTTGATGAAAGTACA
CGAGCATCAAAAAGAAATCAAGCTACAATGGGTCAATATGATTTATTGATAAGTGCTGTG
ACAGGTGAAGCATTATGGCGTTTTAGTGCAAGTGACATTCAAAGTGGTTTTGAAGGTGAC
CGAAGGGATAAAATTATTCGAACATATGTTAGAAATGCCTACAACTATCATCTTAGTGAA
ATTTTCTATACAATCATAACCGAATATACCGATTGGGAGCGAACGAATCAGCATCCAATT
ATCACACGTGATTCCGCCGTGTCAGCATTGTCAGACGCACAATATGTGGCGCCATTAGTC
CATACAGCTGACCTTTTAACATCGATGAATAGCGCACAAGAGGGTGAAAGTGGCCCGAAA
TGCTTCTTTTCTGTCTTTGATTATCAGACAAAAGATGGTGACTACCCACAACGAATGGGT
ACAGTACATGGTGAAGATTTGCCATATGTATTTGGCGCACCACTCATCGATGGCTTCAGT
CACTTTCCGAGAAATTACACCAAATCGGAAATCGCTCTCTCGGAGGCAATTATGATTTAT
TGGAGCAATTTTGTACGAACCGGAAATCCCAATGAGCATCATCGGCAGGACACAATTTTA
GCCGCATCCAAAGAGAGGAATCGGTTTCGTAGTATCACATGGGAACAATATGATCCTATT
CATCAAAAATATCTTGAAATCGGTATGAAGCCAAAGATGAAAAACCATTTTCGTGCCCAT
CAATTGTCAATATGGCTGCGACTCATACCCGAAATGCATAAACTTGGTGCTGGTATGGAA
GATGTACTAACTCGCCACAACCTATTCAAAAATCACGATGATATGTCCCTGTACGATGGT
CACGTGCGACCAGATTTATTTTCGCGTTTGCCCATTTTTGATGAGAACTATAAACGCCGC
AACAATTTTAGCTTGGAATTAAATGGAATGACTACAATGGAGCCACTCGCACTCACCACA
TGTCTCCCGATTAGTAATTTGAGTGGTAACGGTCCAACGGTCACCACAAATTCAAGTGAT
TCATCGGCATTTGAAGGCTACACAGCATACTCGACAGCACTTAGTGTGACTATCGCAATA
GGCTGTAGTTTACTAATTTTAAATGTCCTAATATTTGCTGGTGTATATTATCAAAGAGAC
AAAACAAGACTCGAAGTAAAAACATTGCAAAAACAATATCAGCAGCGAAGTGGTCATCAG
CAATCTTTTGATTCGATAAAACATGCACACTATCATCTTGGTCAGACTGTGGTTGATGTG
GAAAATGTGGATACTGGTGCTCTGATGGAAAAATCCCCGCATATTTGTTCCAATTCTATG
CAAATCAATGTAATGAAAAACAATTCGCCAGCACAGTCGACTACACAAAATAAAGTGCCA
ATGGCAAACAATACAGCTTACAAACCAAGAGCAGAACACGTTACAATTCCCATCAAGAAT
CAGCCCCAACAAACTGCTCCACAACAGCAACAACCACAACAAACGTTCGGAAGAACGGAA
ACATCATTCAATAATTCAGGAATGATGACGCTGCCAAAGCAAAATGTACATATTCCAATG
AGCTATGCACGCAATGAGTGTATGACAATGGCAACTTTACCTAGAAATAGTAACTTAAAT
AATTCAGCAGTGGAACAGACGAGCAAGCAGCAAGTTGTAGGAAATCATGTACGAGCGCAG
ACAGTGAATCGTGCTCAAAATAACAACAGTCCAATGGGACATAGTCATCAGAAAAGCTGC
CATTCACATCTACCAACAGCGGCAATGAGTGATCTCTAG
>g10362.t1 Gene=g10362 Length=952
MLAVCQLLIVLILDVTLAAHVDIYKNARLGTRIVQTRFGRLQGLVLPLDNYKFLKPVEAF
LAVPYATPPTKSNRFGPTRTPSPWDGVRKTNNFSAVCPQRLPEIQNEEEALKKMPKGRLE
YLKRLLPFLQNQSEDCLYLNVFSPLHAAVQEKKLPVLVFIHGESFEWNSGNPYDGSILAS
YAEIIVVTLNYRLGILGFLNANPAPHIRARVANYGLMDQMAALHWIQQNIEKFGGNPSMV
TLAGHGTGAACIDFLMSSPSMVPGLFHRAILMSGSAYSSWALVEDPVIYAVKLAKELNCS
IPEDLIKDHESIVDCLREVPLEDLYAVDIQPPNFLSAFGPSVDGVVIRPGRSNQDLDEST
RASKRNQATMGQYDLLISAVTGEALWRFSASDIQSGFEGDRRDKIIRTYVRNAYNYHLSE
IFYTIITEYTDWERTNQHPIITRDSAVSALSDAQYVAPLVHTADLLTSMNSAQEGESGPK
CFFSVFDYQTKDGDYPQRMGTVHGEDLPYVFGAPLIDGFSHFPRNYTKSEIALSEAIMIY
WSNFVRTGNPNEHHRQDTILAASKERNRFRSITWEQYDPIHQKYLEIGMKPKMKNHFRAH
QLSIWLRLIPEMHKLGAGMEDVLTRHNLFKNHDDMSLYDGHVRPDLFSRLPIFDENYKRR
NNFSLELNGMTTMEPLALTTCLPISNLSGNGPTVTTNSSDSSAFEGYTAYSTALSVTIAI
GCSLLILNVLIFAGVYYQRDKTRLEVKTLQKQYQQRSGHQQSFDSIKHAHYHLGQTVVDV
ENVDTGALMEKSPHICSNSMQINVMKNNSPAQSTTQNKVPMANNTAYKPRAEHVTIPIKN
QPQQTAPQQQQPQQTFGRTETSFNNSGMMTLPKQNVHIPMSYARNECMTMATLPRNSNLN
NSAVEQTSKQQVVGNHVRAQTVNRAQNNNSPMGHSHQKSCHSHLPTAAMSDL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g10362.t1 | Gene3D | G3DSA:3.40.50.1820 | - | 31 | 620 | 1.6E-171 |
| 16 | g10362.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 926 | 952 | - |
| 17 | g10362.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 926 | 944 | - |
| 2 | g10362.t1 | PANTHER | PTHR43903 | NEUROLIGIN | 7 | 905 | 0.0 |
| 3 | g10362.t1 | PANTHER | PTHR43903:SF16 | GH07829P | 7 | 905 | 0.0 |
| 1 | g10362.t1 | Pfam | PF00135 | Carboxylesterase family | 32 | 605 | 2.2E-138 |
| 9 | g10362.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 18 | - |
| 10 | g10362.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 1 | - |
| 11 | g10362.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 2 | 13 | - |
| 13 | g10362.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 14 | 18 | - |
| 8 | g10362.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 19 | 712 | - |
| 12 | g10362.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 713 | 737 | - |
| 7 | g10362.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 738 | 952 | - |
| 15 | g10362.t1 | ProSitePatterns | PS00941 | Carboxylesterases type-B signature 2. | 134 | 144 | - |
| 4 | g10362.t1 | SUPERFAMILY | SSF53474 | alpha/beta-Hydrolases | 32 | 611 | 5.42E-117 |
| 5 | g10362.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 18 | - |
| 14 | g10362.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 715 | 737 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K01044 (carboxylesterase 1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
