General information for g10402.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Guanine nucleotide-binding protein subunit beta-1.
Parent gene
- The parent gene g10402 is located on chr_1: 9567301..9568734 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10402 | g10402.t1 | TTS | g10402.t1 | 9561301 | 9561301 |
| chr_1 | g10402 | g10402.t1 | isoform | g10402.t1 | 9561446 | 9568734 |
| chr_1 | g10402 | g10402.t1 | exon | g10402.t1.exon1 | 9561446 | 9561552 |
| chr_1 | g10402 | g10402.t1 | cds | g10402.t1.CDS1 | 9561446 | 9561552 |
| chr_1 | g10402 | g10402.t1 | exon | g10402.t1.exon2 | 9561621 | 9561837 |
| chr_1 | g10402 | g10402.t1 | cds | g10402.t1.CDS2 | 9561621 | 9561837 |
| chr_1 | g10402 | g10402.t1 | exon | g10402.t1.exon3 | 9561900 | 9562130 |
| chr_1 | g10402 | g10402.t1 | cds | g10402.t1.CDS3 | 9561900 | 9562130 |
| chr_1 | g10402 | g10402.t1 | exon | g10402.t1.exon4 | 9562205 | 9562405 |
| chr_1 | g10402 | g10402.t1 | cds | g10402.t1.CDS4 | 9562205 | 9562405 |
| chr_1 | g10402 | g10402.t1 | exon | g10402.t1.exon5 | 9562753 | 9562962 |
| chr_1 | g10402 | g10402.t1 | cds | g10402.t1.CDS5 | 9562753 | 9562962 |
| chr_1 | g10402 | g10402.t1 | exon | g10402.t1.exon6 | 9563098 | 9563160 |
| chr_1 | g10402 | g10402.t1 | cds | g10402.t1.CDS6 | 9563098 | 9563160 |
| chr_1 | g10402 | g10402.t1 | exon | g10402.t1.exon7 | 9566649 | 9566672 |
| chr_1 | g10402 | g10402.t1 | cds | g10402.t1.CDS7 | 9566649 | 9566672 |
| chr_1 | g10402 | g10402.t1 | exon | g10402.t1.exon8 | 9567301 | 9568600 |
| chr_1 | g10402 | g10402.t1 | cds | g10402.t1.CDS8 | 9567301 | 9568600 |
| chr_1 | g10402 | g10402.t1 | exon | g10402.t1.exon9 | 9568664 | 9568734 |
| chr_1 | g10402 | g10402.t1 | cds | g10402.t1.CDS9 | 9568664 | 9568734 |
| chr_1 | g10402 | g10402.t1 | TSS | g10402.t1 | NA | NA |
Sequences
>g10402.t1 Gene=g10402 Length=2424
ATGGCAGAAGAAAGATTAACATTTTTGAAAAAGATGGATATAAGATGCAAATCTAGTAAT
ATAATATTTAGAAATAACTCGTATGGACTTTGGTTGAGTTCGCTTTTATTTTTATCTTAT
CTACAGACAATTTTGCGAAATCCGTATACAATTCAACTGGAATATGAACTTATTACCGTA
CTAATTGCTGGAATGATGCTTCAATCAATTGAAATATTTATTAGTTTCGTTTATATTGAT
CAACTAAACATATTAAAATTTCTAATGAAAATTTTTCCGACAATCGTCATTACAACTATT
TTCAACTTGATACTCAACCAAGATATGATATTCAGCTTATTTACAAGCTCAACCGTTATG
TTGATCTATTATTTATTGCTAATGTATACACTGAAATCAATGCCACGCTGTTTTACGTTT
GGAGAGGCAACTATAGTGGCTCAAGGACTTGTTATATTTCTTTACAACTGCTTCCTTCAA
CTGCCTTATATTAATCAAGTGACAACAATATCAAATCAACTCAACATAATTTTACAAATG
GGACTTTTAGATGTGCTCTTTCTTATAATTACAACTCATTTCATTCCTGTATTTCGGAAA
TGGTACCTATTCTATCCACTCTTATTATTTTTAATAATAACACTCTGCTTGACGTTAGTG
AATGGTGAGAGTGCAGCTGTCATTTTATGGAATTTTGTATTTAGCGATATCGAAAGAAGT
GCCATAGTTGTGGGATATACAATTTTTCTTATATTAGCTGCGTATACAATATGGATTCAA
ATCAAAAAGAATCAAAGAGGTTCAACAGCAACACGAAAAATATTTCATGTGCTCATCGTT
CTTGTTTACTTGCCAGGATTAATGCGTCAATGCTATTTTCTTTATGTAGCATCAGTTGTA
ATCCTAGCAATTTTAATAATAATTGAATTAGCTCGAGTGATTAAATTATATCCTATCGCT
GAAATATTAGATGCAGCTGTTGTTGCCTTCATTGATGAACAAGATTCTGGAAATATTGCA
TTGACACCGATTTATCTCCTCATTGGATGCTCTATACCTTTATGGATTCATAATTCACCT
TGTGACATGACTAATTCAAGTGGTTCTGAACTTCTACCATTGCTTGCGGGAATTTTATCG
ATTGGAATTGGCGATACATTTGCTAGTGCAATAGGATCGAAAATCGGAAGACATAAATGG
AGTAAAAATTCACAAAAATCTGTTGAAGGAACACTTGCAAGTATTTTTGCTCAAGGAATA
TTTATTTATGGTTTATGTACACTGCAGTTTTTAAATTTAAGTACAAGACTGATGATCATA
TGTGGAGTAGCTGTGATTTCAAATGCTCTCATTGAGGCATTTACTCTTCAAGAATACCAA
TTCATTTTTGGTCAGGTGAAAATGAATGAATTGGACGCCTTAAGACAAGAAGCTGAAACA
TTAAAAAATGCTATTCGTGATGCACGGAAAGCAGCATGCGACACCAGCCTCGTGCAGGCA
ACGAATAATCTGGAACCAATTGGTCGCATTCAAATGCGTACCAGACGCACATTGCGTGGT
CATTTAGCAAAAATTTATGCTATGCACTGGGGAAGTGATTCGAGAAATTTAGTGTCAGCA
TCTCAAGATGGAAAATTGATTGTCTGGGATTCACATACAACAAACAAGGTACACGCAATA
CCTCTACGTAGTTCTTGGGTTATGACATGCGCGTATGCACCATCCGGCAGTTTTGTTGCA
TGTGGCGGTTTGGATAATATCTGTTCAATATATAGCTTAAAGACTAGAGAAGGAAATGTG
CGTGTATCACGTGAACTGCCTGGCCATACTGGCTACTTATCTTGTTGTCGATTCTTGGAT
GATAATCAGATAGTAACAAGTTCAGGAGATATGTCATGCGGATTATGGGATATAGAGACG
GGCCAGCAATGTACATCGTTTTTGGGACATACTGGTGATGTAATGGCGCTGTCATTGTCA
CCGCATTGTAGAGCGTTCGTTTCAGGAGCTTGCGATGCTTCAGCTAAATTATGGGACATT
CGAGAAGGTCAATGCAAGCAAACCTTCCCTGGTCATGAAAGTGATATTAACGCCGTAACA
TTCTTTCCCAATGGCTATGCATTTGCAACTGGTTCAGATGATGCCACTTGCCGTCTTTTT
GATATCCGTGCCGATCAGGAATTGGCAATGTATTCACATGATAACATCATTTGTGGTATA
ACATCTGTTGCATTTTCAAAATCTGGACGTCTTTTATTGGCCGGCTATGATGATTTCAAT
TGCAATGTATGGGATACTATGAAAGCTGAACGAGCTGGTATCTTGGCCGGCCACGATAAC
CGCGTATCATGTCTAGGAGTTACAGAAAACGGCATGGCTGTAGCAACAGGGTCGTGGGAT
TCATTTTTACGTGTATGGAACTAA
>g10402.t1 Gene=g10402 Length=807
MAEERLTFLKKMDIRCKSSNIIFRNNSYGLWLSSLLFLSYLQTILRNPYTIQLEYELITV
LIAGMMLQSIEIFISFVYIDQLNILKFLMKIFPTIVITTIFNLILNQDMIFSLFTSSTVM
LIYYLLLMYTLKSMPRCFTFGEATIVAQGLVIFLYNCFLQLPYINQVTTISNQLNIILQM
GLLDVLFLIITTHFIPVFRKWYLFYPLLLFLIITLCLTLVNGESAAVILWNFVFSDIERS
AIVVGYTIFLILAAYTIWIQIKKNQRGSTATRKIFHVLIVLVYLPGLMRQCYFLYVASVV
ILAILIIIELARVIKLYPIAEILDAAVVAFIDEQDSGNIALTPIYLLIGCSIPLWIHNSP
CDMTNSSGSELLPLLAGILSIGIGDTFASAIGSKIGRHKWSKNSQKSVEGTLASIFAQGI
FIYGLCTLQFLNLSTRLMIICGVAVISNALIEAFTLQEYQFIFGQVKMNELDALRQEAET
LKNAIRDARKAACDTSLVQATNNLEPIGRIQMRTRRTLRGHLAKIYAMHWGSDSRNLVSA
SQDGKLIVWDSHTTNKVHAIPLRSSWVMTCAYAPSGSFVACGGLDNICSIYSLKTREGNV
RVSRELPGHTGYLSCCRFLDDNQIVTSSGDMSCGLWDIETGQQCTSFLGHTGDVMALSLS
PHCRAFVSGACDASAKLWDIREGQCKQTFPGHESDINAVTFFPNGYAFATGSDDATCRLF
DIRADQELAMYSHDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTMKAERAGILAGHDN
RVSCLGVTENGMAVATGSWDSFLRVWN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 48 | g10402.t1 | CDD | cd00200 | WD40 | 515 | 807 | 2.79899E-90 |
| 18 | g10402.t1 | Coils | Coil | Coil | 464 | 491 | - |
| 17 | g10402.t1 | Gene3D | G3DSA:2.130.10.10 | - | 468 | 807 | 9.5E-142 |
| 7 | g10402.t1 | PANTHER | PTHR19850:SF28 | GUANINE NUCLEOTIDE-BINDING PROTEIN SUBUNIT BETA-4 | 468 | 807 | 1.4E-207 |
| 8 | g10402.t1 | PANTHER | PTHR19850 | GUANINE NUCLEOTIDE-BINDING PROTEIN BETA G PROTEIN BETA | 468 | 807 | 1.4E-207 |
| 12 | g10402.t1 | PRINTS | PR00319 | Beta G protein (transducin) signature | 518 | 534 | 3.1E-31 |
| 10 | g10402.t1 | PRINTS | PR00320 | G protein beta WD-40 repeat signature | 537 | 551 | 7.7E-6 |
| 13 | g10402.t1 | PRINTS | PR00319 | Beta G protein (transducin) signature | 537 | 551 | 3.1E-31 |
| 15 | g10402.t1 | PRINTS | PR00319 | Beta G protein (transducin) signature | 556 | 571 | 3.1E-31 |
| 14 | g10402.t1 | PRINTS | PR00319 | Beta G protein (transducin) signature | 574 | 591 | 3.1E-31 |
| 9 | g10402.t1 | PRINTS | PR00320 | G protein beta WD-40 repeat signature | 624 | 638 | 7.7E-6 |
| 11 | g10402.t1 | PRINTS | PR00320 | G protein beta WD-40 repeat signature | 666 | 680 | 7.7E-6 |
| 6 | g10402.t1 | Pfam | PF00400 | WD domain, G-beta repeat | 515 | 550 | 5.2E-4 |
| 3 | g10402.t1 | Pfam | PF00400 | WD domain, G-beta repeat | 604 | 637 | 0.03 |
| 2 | g10402.t1 | Pfam | PF00400 | WD domain, G-beta repeat | 643 | 679 | 0.076 |
| 4 | g10402.t1 | Pfam | PF00400 | WD domain, G-beta repeat | 683 | 721 | 5.5E-7 |
| 1 | g10402.t1 | Pfam | PF00400 | WD domain, G-beta repeat | 733 | 765 | 2.6E-4 |
| 5 | g10402.t1 | Pfam | PF00400 | WD domain, G-beta repeat | 774 | 807 | 0.0061 |
| 19 | g10402.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1 | 20 | - |
| 46 | g10402.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 21 | 45 | - |
| 29 | g10402.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 46 | 56 | - |
| 34 | g10402.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 57 | 80 | - |
| 24 | g10402.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 81 | 86 | - |
| 36 | g10402.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 87 | 105 | - |
| 30 | g10402.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 106 | 110 | - |
| 43 | g10402.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 111 | 131 | - |
| 23 | g10402.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 132 | 142 | - |
| 41 | g10402.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 143 | 164 | - |
| 31 | g10402.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 165 | 175 | - |
| 45 | g10402.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 176 | 195 | - |
| 26 | g10402.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 196 | 201 | - |
| 40 | g10402.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 202 | 220 | - |
| 33 | g10402.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 221 | 239 | - |
| 39 | g10402.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 240 | 258 | - |
| 21 | g10402.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 259 | 269 | - |
| 35 | g10402.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 270 | 286 | - |
| 32 | g10402.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 287 | 291 | - |
| 37 | g10402.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 292 | 311 | - |
| 20 | g10402.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 312 | 338 | - |
| 47 | g10402.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 339 | 356 | - |
| 27 | g10402.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 357 | 370 | - |
| 44 | g10402.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 371 | 391 | - |
| 22 | g10402.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 392 | 411 | - |
| 42 | g10402.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 412 | 431 | - |
| 28 | g10402.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 432 | 436 | - |
| 38 | g10402.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 437 | 456 | - |
| 25 | g10402.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 457 | 807 | - |
| 71 | g10402.t1 | ProSitePatterns | PS00678 | Trp-Asp (WD) repeats signature. | 537 | 551 | - |
| 70 | g10402.t1 | ProSitePatterns | PS00678 | Trp-Asp (WD) repeats signature. | 624 | 638 | - |
| 69 | g10402.t1 | ProSitePatterns | PS00678 | Trp-Asp (WD) repeats signature. | 752 | 766 | - |
| 72 | g10402.t1 | ProSiteProfiles | PS50294 | Trp-Asp (WD) repeats circular profile. | 518 | 807 | 56.052 |
| 73 | g10402.t1 | ProSiteProfiles | PS50082 | Trp-Asp (WD) repeats profile. | 518 | 559 | 13.783 |
| 78 | g10402.t1 | ProSiteProfiles | PS50082 | Trp-Asp (WD) repeats profile. | 606 | 646 | 9.706 |
| 75 | g10402.t1 | ProSiteProfiles | PS50082 | Trp-Asp (WD) repeats profile. | 647 | 688 | 14.184 |
| 76 | g10402.t1 | ProSiteProfiles | PS50082 | Trp-Asp (WD) repeats profile. | 689 | 730 | 12.848 |
| 77 | g10402.t1 | ProSiteProfiles | PS50082 | Trp-Asp (WD) repeats profile. | 740 | 774 | 8.771 |
| 74 | g10402.t1 | ProSiteProfiles | PS50082 | Trp-Asp (WD) repeats profile. | 775 | 807 | 14.452 |
| 67 | g10402.t1 | SMART | SM00320 | WD40_4 | 511 | 550 | 5.5E-7 |
| 68 | g10402.t1 | SMART | SM00320 | WD40_4 | 553 | 592 | 0.012 |
| 64 | g10402.t1 | SMART | SM00320 | WD40_4 | 599 | 637 | 8.2E-6 |
| 65 | g10402.t1 | SMART | SM00320 | WD40_4 | 640 | 679 | 3.5E-6 |
| 66 | g10402.t1 | SMART | SM00320 | WD40_4 | 682 | 721 | 1.7E-9 |
| 63 | g10402.t1 | SMART | SM00320 | WD40_4 | 724 | 765 | 9.7E-4 |
| 62 | g10402.t1 | SMART | SM00320 | WD40_4 | 768 | 807 | 1.1E-4 |
| 16 | g10402.t1 | SUPERFAMILY | SSF50978 | WD40 repeat-like | 474 | 807 | 9.46E-78 |
| 55 | g10402.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 20 | 42 | - |
| 54 | g10402.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 57 | 79 | - |
| 58 | g10402.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 86 | 105 | - |
| 59 | g10402.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 109 | 131 | - |
| 61 | g10402.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 144 | 166 | - |
| 60 | g10402.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 176 | 198 | - |
| 57 | g10402.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 205 | 227 | - |
| 49 | g10402.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 242 | 261 | - |
| 51 | g10402.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 274 | 288 | - |
| 53 | g10402.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 292 | 314 | - |
| 50 | g10402.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 337 | 356 | - |
| 52 | g10402.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 371 | 393 | - |
| 56 | g10402.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 412 | 431 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0007165 | signal transduction | BP |
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K04536 (guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
