General information for g10458.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as UDP-glucuronic acid decarboxylase 1.
Parent gene
- The parent gene g10458 is located on chr_1: 9909484..9910713 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10458 | g10458.t1 | TSS | g10458.t1 | 9909418 | 9909418 |
| chr_1 | g10458 | g10458.t1 | isoform | g10458.t1 | 9909484 | 9910713 |
| chr_1 | g10458 | g10458.t1 | exon | g10458.t1.exon1 | 9909484 | 9910713 |
| chr_1 | g10458 | g10458.t1 | cds | g10458.t1.CDS1 | 9909484 | 9910713 |
| chr_1 | g10458 | g10458.t1 | TTS | g10458.t1 | 9910887 | 9910887 |
Sequences
>g10458.t1 Gene=g10458 Length=1230
ATGTTTATAAGACGAAGGATGAAGCCAATTCTGTTAGTTTTAGTTATTTTAATAGTTTTG
ATTCTGTCAGCTTACAAGACTACATTATCAGCAGATGTCACACCCACAGATCTGCATTAT
AATGCAGAAATTAAGTCAACTTCGAATAGTAAAGAGAAATTAGAGCAAGCACATATGAAA
ATAAAGCAATTAGAGGCGAGAATAGAAGAACTTGAAAAGAAGATGTCTGTGAAGACATAT
GCAACTGTAAAATTTTTAAATTACCAGAGTAGAAAAAAAATATTGATAACTGGTGGCGCA
GGTTTTGTTGGTTCTCACTTAGTCGACTATTTAATGAAAGAAGGACATGAAGTAATTGTT
GCAGATAATTTCTTTACGGGCAGAAAACATAATGTACAACATTGGATAGGTCATCAAAAT
TTTGAACTCATCTCACATGATATTGTTAATCCATTATATATTGAAGTAGATGAAATTTAT
CATTTGGCATCTCCTGCGTCACCAATTCATTATATGCAAAATCCAGTTAAAACTATCAAA
GTTAATACACTTGGTACAATAAACATGCTCGGATTAGCACGGCGTGTAGGTGCCAAGATT
TTAATTGCTTCCACATCTGAAGTCTATGGCGATCCCGATTTACATCATCATCCTCAAACT
GAAACTTATTGGGGGCATGTAAACCCAATTGGACCGAGAGCATGCTATGATGAAGGTAAA
CGTGTTGCCGAAACTCTTAGTTATGCATATGCTAAGCAGGAGAAAGTTGACGTTCGAGTT
GCAAGAATTTTTAATACTTATGGACCAAGAATGCATTTTAATGATGGAAGAGTTGTCGGT
AATTTTATACTTCAAGCTCTCAAAAATGAATCTATTACGATTTATGGTGATGGAAAACAA
ACAAGAAGTTTTCAATATGTGAGTGATTTGGTAGACGGATTAGCAGCACTCATGAAATCA
AACTATACACAACCAGTGAATCTTGGTAATCCACAAGAGCACTCAATTCAGGAATTTGCT
GAAATAATTAGCGGGCTTGTTGGTGTCAAAACAAAAACTGAACATCTTAATTCTGTAGAA
GATGATCCGCAAAGAAGAAAACCTGATATCACAAGAGCAAAGAATTTGTTGAATTGGGAA
CCAAAAATCTCATTAAAAAAAGGCTTGCAAATGACGATAGAATATTTTCGAAATGAACTC
GAGTCAGAGAATATGGGTAGAGTCAAATAA
>g10458.t1 Gene=g10458 Length=409
MFIRRRMKPILLVLVILIVLILSAYKTTLSADVTPTDLHYNAEIKSTSNSKEKLEQAHMK
IKQLEARIEELEKKMSVKTYATVKFLNYQSRKKILITGGAGFVGSHLVDYLMKEGHEVIV
ADNFFTGRKHNVQHWIGHQNFELISHDIVNPLYIEVDEIYHLASPASPIHYMQNPVKTIK
VNTLGTINMLGLARRVGAKILIASTSEVYGDPDLHHHPQTETYWGHVNPIGPRACYDEGK
RVAETLSYAYAKQEKVDVRVARIFNTYGPRMHFNDGRVVGNFILQALKNESITIYGDGKQ
TRSFQYVSDLVDGLAALMKSNYTQPVNLGNPQEHSIQEFAEIISGLVGVKTKTEHLNSVE
DDPQRRKPDITRAKNLLNWEPKISLKKGLQMTIEYFRNELESENMGRVK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 15 | g10458.t1 | CDD | cd05230 | UGD_SDR_e | 92 | 397 | 0.0 |
| 9 | g10458.t1 | Coils | Coil | Coil | 47 | 81 | - |
| 7 | g10458.t1 | Gene3D | G3DSA:3.40.50.720 | - | 88 | 212 | 4.5E-48 |
| 8 | g10458.t1 | Gene3D | G3DSA:3.40.50.720 | - | 213 | 404 | 3.2E-65 |
| 2 | g10458.t1 | PANTHER | PTHR43078 | UDP-GLUCURONIC ACID DECARBOXYLASE-RELATED | 86 | 402 | 9.6E-164 |
| 3 | g10458.t1 | PANTHER | PTHR43078:SF6 | UDP-GLUCURONIC ACID DECARBOXYLASE 1 | 86 | 402 | 9.6E-164 |
| 1 | g10458.t1 | Pfam | PF16363 | GDP-mannose 4,6 dehydratase | 95 | 392 | 1.7E-60 |
| 11 | g10458.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 31 | - |
| 12 | g10458.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 9 | - |
| 13 | g10458.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 10 | 22 | - |
| 14 | g10458.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 23 | 31 | - |
| 10 | g10458.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 32 | 409 | - |
| 4 | g10458.t1 | SUPERFAMILY | SSF51735 | NAD(P)-binding Rossmann-fold domains | 86 | 400 | 4.61E-90 |
| 6 | g10458.t1 | SignalP_EUK | SignalP-TM | SignalP-TM | 1 | 30 | - |
| 5 | g10458.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 31 | - |
| 16 | g10458.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 9 | 31 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
- This transcript has been annotated with K08678 (UDP-glucuronate decarboxylase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
