Gene loci information

Transcript annotation

  • This transcript has been annotated as Heparan-alpha-glucosaminide N-acetyltransferase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g10496 g10496.t5 TTS g10496.t5 10204496 10204496
chr_1 g10496 g10496.t5 isoform g10496.t5 10204623 10206717
chr_1 g10496 g10496.t5 exon g10496.t5.exon1 10204623 10205564
chr_1 g10496 g10496.t5 cds g10496.t5.CDS1 10204623 10205564
chr_1 g10496 g10496.t5 exon g10496.t5.exon2 10205623 10206017
chr_1 g10496 g10496.t5 cds g10496.t5.CDS2 10205623 10206017
chr_1 g10496 g10496.t5 exon g10496.t5.exon3 10206091 10206272
chr_1 g10496 g10496.t5 cds g10496.t5.CDS3 10206091 10206193
chr_1 g10496 g10496.t5 exon g10496.t5.exon4 10206645 10206717
chr_1 g10496 g10496.t5 TSS g10496.t5 10206717 10206717

Sequences

>g10496.t5 Gene=g10496 Length=1592
AGTGAGAGCGAATGAGTGAGAGTAGAAGTAATGAACAAAAATAACAAAACGCAAAATTTA
TTAACATTCGTCTAATTGAATTGCGTCTTTTCACTAAAGATCATGGCCCATTTGTGCATC
CAAATGTAGTTGTTGATAATGTCTTTTGGAGTATGCAAGAGCAGCTTGGTGAATTTGGTG
TTTATGATCTTACAATCAAACCTTCTGGTGCAACAGCATTCGAAATTGCAAAGGAGCCAG
TCAGCACATTTTCATCACTCATTATCGTGTTATTCATCGTCCTATGTATTTATTGGATAT
TCAAATATATCAACAAATTCTACATAAAAAGACTAGCAAGTCAAGTGACTGAAATTAATA
TACCACCTGATTCACCTGAAAATGTGAATGAACCAAGTGAACCAAAAACAAAGAAAAGAC
TTAAAAGTTTGGATATTTTTCGCGGAATTGCAATCGTTTTGATGATTTTTGTCAATAGTG
GTGGTGGTCATTATTGGTGGATTGAACATGCAATTTGGAATGGTTTGCACTTTGCTGATT
TAGTTTTTCCCTGGTTTTTATTTATAATGGGAGTTTGCATACCTTTAAGTATCAAATCGC
AAATTAATCGACAAGTCGCTATGTCTAGTATTGTAAAGAAAGTTATCAAGCGGTCAATCA
CATTATTTCTCCTTGGTTTATGTCTCAATACGCTATATGGTGCGTCTTTTCAAAGCATTC
GTATAATGGGAGTTTTGCAACGATTTGGAATCGCTTATTTGGTTATTTCACTTATTCATC
TTGCTTTTGTCAGCAATTCAATCAATGCAGAAACAAGAATCCAACAGTTATTTTATGATG
TTCGAATGATATGGAAACAATGGTTGATTGTTCTTAGTTTTGTAATCTTCCACTTGATTA
TGATTTTTGGAATAAAAGCATCAAATTGTGAGCGAGGATATTTTGGTCCAGGTGGTATTC
ATGAATACATGGCACATGAAAATTGCACGGGTGGCATCGCTGGATTTGTTGATCGAAATG
TTTTGGGTGAGAGTCACATGTATCAACGTGCGAAAATTCGATCAGTTTATGATGCTCAAG
TATTTGATCCTGAAGGAGTTTTTGGATGCTTGCTGACATGTTTGCAAGTATTTTTGGGTC
TCCAGTGTGGAGTTACTTTATTGGTTTACCCAACAGCAAAAGAAAGATTAAGACGATGGA
TAATTTGGGGAATTGGATTGCTGATTCTTACATGTTTTTTAACTTTTTTCTCAGTTGAAA
ATGGTCTCATACCAATTAATAAGAATTTATGGTCATTATCATTTGTTACCATCACTGCAG
GCTTAGCATTTCTTCTTCTTAGTTTAATTTATTTTTTGGTTGATGTTAAAAACATTGGTG
ACGATTTTTGGACAATTTTCTTATATCCTGGAATGAATGCGATTGTTCTTTATGTAGGTC
ACTCTGTCTTTCACAGCATGTGGCCTTTTCATTGGTCAGTTGATAATATGAACACTCATT
TTCTTTTGCTACTAGAAAATTTATATACTGTCATGATTTGGGTACTCATTTCCCACTATT
TGTATCACAAAGAACTGTTTTATAATATTTAA

>g10496.t5 Gene=g10496 Length=479
MQEQLGEFGVYDLTIKPSGATAFEIAKEPVSTFSSLIIVLFIVLCIYWIFKYINKFYIKR
LASQVTEINIPPDSPENVNEPSEPKTKKRLKSLDIFRGIAIVLMIFVNSGGGHYWWIEHA
IWNGLHFADLVFPWFLFIMGVCIPLSIKSQINRQVAMSSIVKKVIKRSITLFLLGLCLNT
LYGASFQSIRIMGVLQRFGIAYLVISLIHLAFVSNSINAETRIQQLFYDVRMIWKQWLIV
LSFVIFHLIMIFGIKASNCERGYFGPGGIHEYMAHENCTGGIAGFVDRNVLGESHMYQRA
KIRSVYDAQVFDPEGVFGCLLTCLQVFLGLQCGVTLLVYPTAKERLRRWIIWGIGLLILT
CFLTFFSVENGLIPINKNLWSLSFVTITAGLAFLLLSLIYFLVDVKNIGDDFWTIFLYPG
MNAIVLYVGHSVFHSMWPFHWSVDNMNTHFLLLLENLYTVMIWVLISHYLYHKELFYNI

Protein features from InterProScan

Transcript Database ID Name Start End E.value
2 g10496.t5 PANTHER PTHR31061 LD22376P 72 476 2.3E-112
3 g10496.t5 PANTHER PTHR31061:SF19 HEPARAN-ALPHA-GLUCOSAMINIDE N-ACETYLTRANSFERASE 72 476 2.3E-112
1 g10496.t5 Pfam PF16401 Domain of unknown function (DUF5009) 89 179 9.9E-9
26 g10496.t5 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 1 32 -
34 g10496.t5 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 33 50 -
20 g10496.t5 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 51 94 -
31 g10496.t5 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 95 115 -
25 g10496.t5 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 116 126 -
35 g10496.t5 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 127 147 -
15 g10496.t5 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 148 167 -
27 g10496.t5 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 168 186 -
22 g10496.t5 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 187 197 -
33 g10496.t5 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 198 217 -
18 g10496.t5 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 218 236 -
30 g10496.t5 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 237 254 -
21 g10496.t5 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 255 314 -
28 g10496.t5 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 315 337 -
17 g10496.t5 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 338 348 -
32 g10496.t5 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 349 368 -
23 g10496.t5 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 369 379 -
36 g10496.t5 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 380 403 -
16 g10496.t5 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 404 414 -
37 g10496.t5 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 415 437 -
24 g10496.t5 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 438 448 -
29 g10496.t5 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 449 471 -
19 g10496.t5 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 472 479 -
8 g10496.t5 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 31 50 -
4 g10496.t5 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 95 117 -
10 g10496.t5 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 130 147 -
12 g10496.t5 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 168 190 -
14 g10496.t5 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 194 216 -
9 g10496.t5 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 237 254 -
6 g10496.t5 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 315 337 -
11 g10496.t5 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 349 368 -
5 g10496.t5 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 383 405 -
13 g10496.t5 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 412 434 -
7 g10496.t5 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 449 471 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005765 lysosomal membrane CC
GO:0015019 heparan-alpha-glucosaminide N-acetyltransferase activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values