Gene loci information

Transcript annotation

  • This transcript has been annotated as Putative Heparan-alpha-glucosaminide N-acetyltransferase.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g10496 g10496.t7 isoform g10496.t7 10205638 10206484
chr_1 g10496 g10496.t7 exon g10496.t7.exon1 10205638 10206017
chr_1 g10496 g10496.t7 cds g10496.t7.CDS1 10205638 10206017
chr_1 g10496 g10496.t7 exon g10496.t7.exon2 10206091 10206484
chr_1 g10496 g10496.t7 cds g10496.t7.CDS2 10206091 10206484
chr_1 g10496 g10496.t7 TSS g10496.t7 10206717 10206717
chr_1 g10496 g10496.t7 TTS g10496.t7 NA NA

Sequences

>g10496.t7 Gene=g10496 Length=774
ATGTCTTGGCTAGAATGGACAGACAGCAGCTTTCGTGGTCTTGATTTGACAAAATTAAAA
GTCGATCAGGCTTATTTTAATATTAGTAATGGAATGAATCAACATTTTTATCTCTATACA
CTCTCACAAGAGTGTATATCATGTCCATTCAGAAAAATCAAAAAAGCTGCAGCATTAAAT
GATACAATTTTGAAACTTGATACAACTCGTAGAATTGAATTGCGTCTTTTCACTAAAGAT
CATGGCCCATTTGTGCATCCAAATGTAGTTGTTGATAATGTCTTTTGGAGTATGCAAGAG
CAGCTTGGTGAATTTGGTGTTTATGATCTTACAATCAAACCTTCTGGTGCAACAGCATTC
GAAATTGCAAAGGAGCCAGTCAGCACATTTTCATCACTCATTATCGTGTTATTCATCGTC
CTATGTATTTATTGGATATTCAAATATATCAACAAATTCTACATAAAAAGACTAGCAAGT
CAAGTGACTGAAATTAATATACCACCTGATTCACCTGAAAATGTGAATGAACCAAGTGAA
CCAAAAACAAAGAAAAGACTTAAAAGTTTGGATATTTTTCGCGGAATTGCAATCGTTTTG
ATGATTTTTGTCAATAGTGGTGGTGGTCATTATTGGTGGATTGAACATGCAATTTGGAAT
GGTTTGCACTTTGCTGATTTAGTTTTTCCCTGGTTTTTATTTATAATGGGAGTTTGCATA
CCTTTAAGTATCAAATCGCAAATTAATCGACAAGTCGCTATGTCTAGTATTGTA

>g10496.t7 Gene=g10496 Length=258
MSWLEWTDSSFRGLDLTKLKVDQAYFNISNGMNQHFYLYTLSQECISCPFRKIKKAAALN
DTILKLDTTRRIELRLFTKDHGPFVHPNVVVDNVFWSMQEQLGEFGVYDLTIKPSGATAF
EIAKEPVSTFSSLIIVLFIVLCIYWIFKYINKFYIKRLASQVTEINIPPDSPENVNEPSE
PKTKKRLKSLDIFRGIAIVLMIFVNSGGGHYWWIEHAIWNGLHFADLVFPWFLFIMGVCI
PLSIKSQINRQVAMSSIV

Protein features from InterProScan

Transcript Database ID Name Start End E.value
2 g10496.t7 PANTHER PTHR31061 LD22376P 154 253 1.3E-27
3 g10496.t7 PANTHER PTHR31061:SF19 HEPARAN-ALPHA-GLUCOSAMINIDE N-ACETYLTRANSFERASE 154 253 1.3E-27
1 g10496.t7 Pfam PF16401 Domain of unknown function (DUF5009) 186 252 1.0E-6
9 g10496.t7 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 1 126 -
13 g10496.t7 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 127 147 -
8 g10496.t7 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 148 191 -
11 g10496.t7 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 192 212 -
10 g10496.t7 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 213 223 -
12 g10496.t7 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 224 244 -
7 g10496.t7 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 245 258 -
5 g10496.t7 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 128 147 -
6 g10496.t7 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 192 214 -
4 g10496.t7 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 227 244 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005765 lysosomal membrane CC
GO:0015019 heparan-alpha-glucosaminide N-acetyltransferase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values