Gene loci information

Transcript annotation

  • This transcript has been annotated as Protein lev-9.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g10549 g10549.t1 TSS g10549.t1 10439345 10439345
chr_1 g10549 g10549.t1 isoform g10549.t1 10439529 10444729
chr_1 g10549 g10549.t1 exon g10549.t1.exon1 10439529 10439586
chr_1 g10549 g10549.t1 cds g10549.t1.CDS1 10439529 10439586
chr_1 g10549 g10549.t1 exon g10549.t1.exon2 10439812 10439931
chr_1 g10549 g10549.t1 cds g10549.t1.CDS2 10439812 10439931
chr_1 g10549 g10549.t1 exon g10549.t1.exon3 10439992 10440183
chr_1 g10549 g10549.t1 cds g10549.t1.CDS3 10439992 10440183
chr_1 g10549 g10549.t1 exon g10549.t1.exon4 10440243 10440577
chr_1 g10549 g10549.t1 cds g10549.t1.CDS4 10440243 10440577
chr_1 g10549 g10549.t1 exon g10549.t1.exon5 10440644 10440677
chr_1 g10549 g10549.t1 cds g10549.t1.CDS5 10440644 10440677
chr_1 g10549 g10549.t1 exon g10549.t1.exon6 10440740 10440868
chr_1 g10549 g10549.t1 cds g10549.t1.CDS6 10440740 10440868
chr_1 g10549 g10549.t1 exon g10549.t1.exon7 10441317 10441708
chr_1 g10549 g10549.t1 cds g10549.t1.CDS7 10441317 10441708
chr_1 g10549 g10549.t1 exon g10549.t1.exon8 10441784 10442195
chr_1 g10549 g10549.t1 cds g10549.t1.CDS8 10441784 10442195
chr_1 g10549 g10549.t1 exon g10549.t1.exon9 10442264 10442418
chr_1 g10549 g10549.t1 cds g10549.t1.CDS9 10442264 10442418
chr_1 g10549 g10549.t1 exon g10549.t1.exon10 10442486 10443832
chr_1 g10549 g10549.t1 cds g10549.t1.CDS10 10442486 10443832
chr_1 g10549 g10549.t1 exon g10549.t1.exon11 10443909 10443966
chr_1 g10549 g10549.t1 cds g10549.t1.CDS11 10443909 10443966
chr_1 g10549 g10549.t1 exon g10549.t1.exon12 10444026 10444379
chr_1 g10549 g10549.t1 cds g10549.t1.CDS12 10444026 10444379
chr_1 g10549 g10549.t1 exon g10549.t1.exon13 10444463 10444501
chr_1 g10549 g10549.t1 cds g10549.t1.CDS13 10444463 10444501
chr_1 g10549 g10549.t1 exon g10549.t1.exon14 10444569 10444729
chr_1 g10549 g10549.t1 cds g10549.t1.CDS14 10444569 10444729
chr_1 g10549 g10549.t1 TTS g10549.t1 NA NA

Sequences

>g10549.t1 Gene=g10549 Length=3786
ATGAAAAATTTTCAACTTTTCTGGATCATCTTAGTTTCAGCCATTTTTTTTCAACGAGGC
TATTCAGGACCAACGACAGTAACAGAGGATCCAGATGATTGGGAAGAAGAAGATGATTCT
TCTGAAGCTGATGATGATGGTCGTGTTTATAAAAATCCTAGAAATTTTCCATCACCTGAC
TGTCCTAGAGACGAAGAACAAGCAACCCTCTTAGGGCAAAAGTGTCTAAGAAAATGTTCA
TCAGATGAAGATTGTAAAAGTAAGAAAAAGAAATGCTTATGTGACGGTGCTTGTGGAATG
TCATGTATCAAACCAGATAGAGAATGTCCTGAACTTGAACATCCAGCATTAGGCACTGTA
GTAATGTCAGGACGAACTTTTGGTTCGAGAGCGAGCTATACTTGTAATCACGGTTATCAT
GTCGTGGGATTGCAAACAAGAGTTTGTCAAGCTTATGGCTCCTGGTCTGGCAGTGAGCCA
GCATGCAAGCAAAATATTTATTGCTTAGCACCACCAACAATCGAGCATGCACGACATTCC
GCACTACCAGAACAAGCAACATTTGATTTAGATTCAACGGTTCAGTATCATTGCCATTTG
GGCTATGCAACCGCGGGTTTCCCTCGAGCTAAATGCTTAGCAATCGATGGACAAGCAAGC
TGGTATGGTCCTGATATTTCCTGTGAACCACGTTCATGTGGACAACCAGTCGATCCAGCG
AACTCAGGATGGCATGCGGGCGAATGCTATACATATGGATGTCGGATAACATATCATTGT
GGAGAAGGCTATGAATTAGTTGGAAAACAAGCTGCAGATTGTCAAGCAGATGGAGTTTGG
GCACCAAAAGAAGTTCCAACTTGTGTTTTGGTAACAGCAGTTCAATGTCCTCAACCGGAT
AATCCACGAAATGGAAAAGCTATTTATACGAGTGTTTCATATAACTCTGTTGTTAGTTAT
GAATGTCGTTATGGTTATACATTGATTGGAGAAAGTTCGAGGCGTTGTGGTGCTGATAAA
AAATGGTCTGGTAGCTTGCCACAATGCAAAGAAATTAATTGCGGTCATCCAGGAACTTTA
TATAATGGTTGGCTAGAGAATGTTGAAGCAGGTTTCGGTTTAGGCTCAAGTATAATTTTC
CGATGTCAGCCAGAGATGTTACTTGTCGGCAATGCATCAACTGTTTGTCAAATAGATGGA
AGATGGAGATATCCATTACCTCAATGTCTTGCACCATGTGTTGTACCAAGTATTTCTCAA
GGAATTGTTGTTCCAATTGAAGTTGATATTCCTGATACAAATGCAACTCAAGCAACACCG
ATAGGAATGGGCATTGGAAGCAGCAAAGTTAGGCATGGAACAATTTTAGAAGTAATTTGC
GATGAACATTATGAATTTCCATTAACATCACTTTCACCTCCAACATGTAATAATGGTACA
TGGTCAACTATACCACGATGTGTGCCTGCAAGATGCAAAACACTCCCAAAAGCACCAAAA
TTTGCTATGGTGATTTCACCAAAGACAGAACATGGCATGAAAGCACGATTTAAATGCAAA
GATGGTTGGCAACTTGCAACTGCAGATGGTAAACCAATAAACGATTCAAATGAACATGTA
TTAACATGCTTATTTGGCAATTGGAGTGGAGAATATCCAATTTGTCAAGAGGTTTATTGT
CAGTTTCTTGGTATCATTCCAAATGGGAAAGTATTATTAGTTGGAAACATGGGTCTTTAT
GATTATCGTCCTTATGTCAAAAAAGTCATAAATAATAAACAAATAATGTATGATTGTGAT
AAGGGCTATGTTCTTGAGAATGGTGCTTCAGGTGCAACTTGTATTGGTGGAAAATGGCAG
CCATCACAACTTCCTGATTGTCTTTTAGGACAACATCCTCGATTGAGATGGACAAGAAAG
AAGAGATCGGTTGATTTAAAATTTACACGTGCCAAATTTATGCTCAATCATTATCGAAAT
ATCAAACGAAAGCACTTTGACCATCATAAAATTGATGAATTTATTAAAAAAGCTGCCGCA
AGAGAGAAAAGAAGTATCATAAATGAAAGTCAAAAACATTTTCTCGAATATCTCAATAAT
ATTGTTCAAAATGAATCAAGAGAGAAGAAAAAACGAGAAAATCGCGATTTTTCTGAGATT
GATAGAGCATATTCAAAATATTATGAGAAAATTAAAGCAAGATATAGAAATTATGTAAAG
AATCTCTTTCCTAATCAAAAGCAAAAAAATTCATTAATCAACAATAGCTATCCAATGCAA
CCTGTTGCAGAAGAGGAAGTGAAAAATACAAGAAAAATTCAAGATGGTCGATGGTTCAAT
GCACCAGAATTTCGATATCGTGCAATACAAAAAGCAAGATCATCTTACACAAAAGATTTA
CAAAATGAAGAAATAGATGCTGATTTAGATGATCAACCAGTTGCAATTCCAACAATTAAT
GATTCAACACGATCAAACAAATATGAGACATCTATAATAAATACAAATGCAAGCATATCA
AATTATTATCCTTCTTATAATGAAAAACAACAACAAATAGAAGAAAATAATGAGAATGGT
GCAAAAAAGCACAGCAGCTCAGTTGATATTGCTGCCAATATTTATGCACAATTACAATCG
CAAATAGTGAGGCGAAAACGTGATACAGATGATGATGGAAAAGATGATGATATTGGTGTA
GTTGGAAAGAAAAAACGTGGACCATGTGAGCCGATAACTGAGCTTGATCATATGCAAATG
GAAATTGTTAAACCTCCAAAAAATCCTAATGATAGTTTTGGTCATGGAATGGTATTGAAA
ATAACGTGCAATAGTGGCTATCATTCAAATATCCAAACAGTCAATTCGACTGTTCGATGT
AATAAAGGTGTTTGGAAGCCAGTTAAACCAGTATGCACAGTAACAAAAGGTCCTTGCTTT
GTACCGTCTGTTGAACATGGAAGTTATTATGAAATGCCATCATCAGATCCGCTAATTGAA
CAAATTAAACCAACAACTAGTCCACTTACACCACTTGCTAGAGTCGATAATGGTATAACA
ATTGCATTTCAATGTGACACTGGCTACAATATTCAAGGATCAAATAGTATCAAATGTATT
GATGGAAATTGGTCAAGTCAAGCATCTCCTGAATGTCTTCCTGCTCCTTGTGTGTTGCCT
GAAATCTTACATGCTGTATATCAAGGCGGTTATCGATTGGGTTTAACTATAGCTCATGGA
TCTCATGTTATGGTAGTTTGTGAAAATGGAGCAGCTAATACGATTCCACCAGTTCAAATG
GATTGTGCACTAGGATTATTGACTCCAACAACAGTCAGTTGTAGTTTCACGGCTTCGCGT
AAATCAAGGGATGATGAAATGAATAGTTTTATTGTTGATGACGGTAATGTAACGACATCT
TCTGAGGAAGGTGGCGATTTTTGTGGACCACCATCAAAAGATCAGGCAATGTTAATTTAT
AAAAATGAAGATACTGAAATAGATGATACTTATCCTGCTGGTACTGAAATTTCCTTCAGT
TGCATTCCAAGTATTACTGGAGAGCGAACAACTTGGAAAATTGTGTGTGAGAATGGTCAT
TGGATCGGAAGAGCACACGATTGTGAGGATGACGAAAGACTTTATAATACACCATTAGCA
AATGGATCTTGTGTCTTTAAAAATACAGATCCACATGTGGCAAATTTCTATAATGACTTA
GAAATAAGAGAAAGTTATGTCGAATTTCCTGCTGGAACAACGCTAATCTCAAGGTACCAT
ATCTGA

>g10549.t1 Gene=g10549 Length=1261
MKNFQLFWIILVSAIFFQRGYSGPTTVTEDPDDWEEEDDSSEADDDGRVYKNPRNFPSPD
CPRDEEQATLLGQKCLRKCSSDEDCKSKKKKCLCDGACGMSCIKPDRECPELEHPALGTV
VMSGRTFGSRASYTCNHGYHVVGLQTRVCQAYGSWSGSEPACKQNIYCLAPPTIEHARHS
ALPEQATFDLDSTVQYHCHLGYATAGFPRAKCLAIDGQASWYGPDISCEPRSCGQPVDPA
NSGWHAGECYTYGCRITYHCGEGYELVGKQAADCQADGVWAPKEVPTCVLVTAVQCPQPD
NPRNGKAIYTSVSYNSVVSYECRYGYTLIGESSRRCGADKKWSGSLPQCKEINCGHPGTL
YNGWLENVEAGFGLGSSIIFRCQPEMLLVGNASTVCQIDGRWRYPLPQCLAPCVVPSISQ
GIVVPIEVDIPDTNATQATPIGMGIGSSKVRHGTILEVICDEHYEFPLTSLSPPTCNNGT
WSTIPRCVPARCKTLPKAPKFAMVISPKTEHGMKARFKCKDGWQLATADGKPINDSNEHV
LTCLFGNWSGEYPICQEVYCQFLGIIPNGKVLLVGNMGLYDYRPYVKKVINNKQIMYDCD
KGYVLENGASGATCIGGKWQPSQLPDCLLGQHPRLRWTRKKRSVDLKFTRAKFMLNHYRN
IKRKHFDHHKIDEFIKKAAAREKRSIINESQKHFLEYLNNIVQNESREKKKRENRDFSEI
DRAYSKYYEKIKARYRNYVKNLFPNQKQKNSLINNSYPMQPVAEEEVKNTRKIQDGRWFN
APEFRYRAIQKARSSYTKDLQNEEIDADLDDQPVAIPTINDSTRSNKYETSIINTNASIS
NYYPSYNEKQQQIEENNENGAKKHSSSVDIAANIYAQLQSQIVRRKRDTDDDGKDDDIGV
VGKKKRGPCEPITELDHMQMEIVKPPKNPNDSFGHGMVLKITCNSGYHSNIQTVNSTVRC
NKGVWKPVKPVCTVTKGPCFVPSVEHGSYYEMPSSDPLIEQIKPTTSPLTPLARVDNGIT
IAFQCDTGYNIQGSNSIKCIDGNWSSQASPECLPAPCVLPEILHAVYQGGYRLGLTIAHG
SHVMVVCENGAANTIPPVQMDCALGLLTPTTVSCSFTASRKSRDDEMNSFIVDDGNVTTS
SEEGGDFCGPPSKDQAMLIYKNEDTEIDDTYPAGTEISFSCIPSITGERTTWKIVCENGH
WIGRAHDCEDDERLYNTPLANGSCVFKNTDPHVANFYNDLEIRESYVEFPAGTTLISRYH
I

Protein features from InterProScan

Transcript Database ID Name Start End E.value
46 g10549.t1 CDD cd00033 CCP 109 163 1.12805E-11
52 g10549.t1 CDD cd00033 CCP 168 229 6.77166E-6
51 g10549.t1 CDD cd00033 CCP 233 289 1.30948E-7
49 g10549.t1 CDD cd00033 CCP 296 350 1.57703E-13
48 g10549.t1 CDD cd00033 CCP 354 409 4.58683E-9
50 g10549.t1 CDD cd00033 CCP 909 972 0.00853269
47 g10549.t1 CDD cd00033 CCP 1018 1052 5.39335E-4
38 g10549.t1 Gene3D G3DSA:2.10.70.10 Complement Module 104 166 3.7E-14
34 g10549.t1 Gene3D G3DSA:2.10.70.10 Complement Module 167 227 1.3E-10
39 g10549.t1 Gene3D G3DSA:2.10.70.10 Complement Module 228 290 1.8E-12
37 g10549.t1 Gene3D G3DSA:2.10.70.10 Complement Module 291 350 9.3E-18
32 g10549.t1 Gene3D G3DSA:2.10.70.10 Complement Module 351 414 4.8E-12
33 g10549.t1 Gene3D G3DSA:2.10.70.10 Complement Module 429 488 6.2E-5
36 g10549.t1 Gene3D G3DSA:2.10.70.10 Complement Module 490 560 5.8E-7
40 g10549.t1 Gene3D G3DSA:2.10.70.10 Complement Module 561 628 1.6E-8
35 g10549.t1 Gene3D G3DSA:2.10.70.10 Complement Module 907 972 2.5E-7
31 g10549.t1 Gene3D G3DSA:2.10.70.10 Complement Module 977 1053 1.1E-10
66 g10549.t1 MobiDBLite mobidb-lite consensus disorder prediction 27 62 -
65 g10549.t1 MobiDBLite mobidb-lite consensus disorder prediction 29 43 -
10 g10549.t1 PANTHER PTHR19325 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING 25 338 0.0
15 g10549.t1 PANTHER PTHR19325:SF531 HIG-ANCHORING SCAFFOLD PROTEIN, ISOFORM G 25 338 0.0
12 g10549.t1 PANTHER PTHR19325 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING 336 416 0.0
17 g10549.t1 PANTHER PTHR19325:SF531 HIG-ANCHORING SCAFFOLD PROTEIN, ISOFORM G 336 416 0.0
14 g10549.t1 PANTHER PTHR19325 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING 412 1013 0.0
19 g10549.t1 PANTHER PTHR19325:SF531 HIG-ANCHORING SCAFFOLD PROTEIN, ISOFORM G 412 1013 0.0
11 g10549.t1 PANTHER PTHR19325 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING 1017 1068 0.0
16 g10549.t1 PANTHER PTHR19325:SF531 HIG-ANCHORING SCAFFOLD PROTEIN, ISOFORM G 1017 1068 0.0
13 g10549.t1 PANTHER PTHR19325 COMPLEMENT COMPONENT-RELATED SUSHI DOMAIN-CONTAINING 1125 1217 0.0
18 g10549.t1 PANTHER PTHR19325:SF531 HIG-ANCHORING SCAFFOLD PROTEIN, ISOFORM G 1125 1217 0.0
1 g10549.t1 Pfam PF00095 WAP-type (Whey Acidic Protein) ‘four-disulfide core’ 60 105 9.5E-5
5 g10549.t1 Pfam PF00084 Sushi repeat (SCR repeat) 109 162 4.6E-9
6 g10549.t1 Pfam PF00084 Sushi repeat (SCR repeat) 168 225 4.1E-4
2 g10549.t1 Pfam PF00084 Sushi repeat (SCR repeat) 233 288 1.7E-8
9 g10549.t1 Pfam PF00084 Sushi repeat (SCR repeat) 296 349 1.4E-9
3 g10549.t1 Pfam PF00084 Sushi repeat (SCR repeat) 354 409 8.9E-7
7 g10549.t1 Pfam PF00084 Sushi repeat (SCR repeat) 592 627 4.9E-4
4 g10549.t1 Pfam PF00084 Sushi repeat (SCR repeat) 909 972 8.8E-4
8 g10549.t1 Pfam PF00084 Sushi repeat (SCR repeat) 1020 1052 7.5E-6
42 g10549.t1 Phobius SIGNAL_PEPTIDE Signal peptide region 1 22 -
43 g10549.t1 Phobius SIGNAL_PEPTIDE_N_REGION N-terminal region of a signal peptide. 1 5 -
44 g10549.t1 Phobius SIGNAL_PEPTIDE_H_REGION Hydrophobic region of a signal peptide. 6 17 -
45 g10549.t1 Phobius SIGNAL_PEPTIDE_C_REGION C-terminal region of a signal peptide. 18 22 -
41 g10549.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 23 1261 -
67 g10549.t1 ProSiteProfiles PS51390 WAP-type ‘four-disulfide core’ domain profile. 53 106 12.712
72 g10549.t1 ProSiteProfiles PS50923 Sushi/CCP/SCR domain profile. 100 164 11.358
68 g10549.t1 ProSiteProfiles PS50923 Sushi/CCP/SCR domain profile. 166 230 8.779
78 g10549.t1 ProSiteProfiles PS50923 Sushi/CCP/SCR domain profile. 231 290 10.737
71 g10549.t1 ProSiteProfiles PS50923 Sushi/CCP/SCR domain profile. 294 351 11.503
75 g10549.t1 ProSiteProfiles PS50923 Sushi/CCP/SCR domain profile. 352 411 10.095
73 g10549.t1 ProSiteProfiles PS50923 Sushi/CCP/SCR domain profile. 426 489 6.034
77 g10549.t1 ProSiteProfiles PS50923 Sushi/CCP/SCR domain profile. 490 557 8.282
70 g10549.t1 ProSiteProfiles PS50923 Sushi/CCP/SCR domain profile. 558 629 7.443
74 g10549.t1 ProSiteProfiles PS50923 Sushi/CCP/SCR domain profile. 907 974 8.044
76 g10549.t1 ProSiteProfiles PS50923 Sushi/CCP/SCR domain profile. 977 1054 8.707
69 g10549.t1 ProSiteProfiles PS50923 Sushi/CCP/SCR domain profile. 1146 1210 7.795
60 g10549.t1 SMART SM00032 CCP_2 109 162 3.5E-11
54 g10549.t1 SMART SM00032 CCP_2 168 228 8.2E-7
53 g10549.t1 SMART SM00032 CCP_2 233 288 1.5E-6
63 g10549.t1 SMART SM00032 CCP_2 296 349 4.5E-16
55 g10549.t1 SMART SM00032 CCP_2 354 409 4.1E-9
57 g10549.t1 SMART SM00032 CCP_2 430 487 9.4
64 g10549.t1 SMART SM00032 CCP_2 492 555 5.6E-5
59 g10549.t1 SMART SM00032 CCP_2 560 627 0.5
56 g10549.t1 SMART SM00032 CCP_2 909 972 1.2E-4
61 g10549.t1 SMART SM00032 CCP_2 992 1052 7.4E-5
58 g10549.t1 SMART SM00032 CCP_2 1057 1114 5.0
62 g10549.t1 SMART SM00032 CCP_2 1148 1208 1.0
21 g10549.t1 SUPERFAMILY SSF57535 Complement control module/SCR domain 109 163 2.97E-13
25 g10549.t1 SUPERFAMILY SSF57535 Complement control module/SCR domain 166 241 2.29E-10
23 g10549.t1 SUPERFAMILY SSF57535 Complement control module/SCR domain 228 291 1.75E-11
22 g10549.t1 SUPERFAMILY SSF57535 Complement control module/SCR domain 294 363 1.39E-18
20 g10549.t1 SUPERFAMILY SSF57535 Complement control module/SCR domain 346 410 5.26E-13
29 g10549.t1 SUPERFAMILY SSF57535 Complement control module/SCR domain 448 495 6.34E-6
27 g10549.t1 SUPERFAMILY SSF57535 Complement control module/SCR domain 495 569 6.21E-8
24 g10549.t1 SUPERFAMILY SSF57535 Complement control module/SCR domain 552 627 2.83E-8
26 g10549.t1 SUPERFAMILY SSF57535 Complement control module/SCR domain 909 974 2.16E-5
28 g10549.t1 SUPERFAMILY SSF57535 Complement control module/SCR domain 1017 1061 3.67E-7
30 g10549.t1 SignalP_EUK SignalP-noTM SignalP-noTM 1 22 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005576 extracellular region CC
GO:0030414 peptidase inhibitor activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values