General information for g10786.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Dual specificity protein phosphatase CDC14A.
Parent gene
- The parent gene g10786 is located on chr_1: 11971869..11975898 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10786 | g10786.t2 | isoform | g10786.t2 | 11971869 | 11975898 |
| chr_1 | g10786 | g10786.t2 | exon | g10786.t2.exon1 | 11971869 | 11972574 |
| chr_1 | g10786 | g10786.t2 | cds | g10786.t2.CDS1 | 11971869 | 11972574 |
| chr_1 | g10786 | g10786.t2 | exon | g10786.t2.exon2 | 11974035 | 11974175 |
| chr_1 | g10786 | g10786.t2 | cds | g10786.t2.CDS2 | 11974035 | 11974175 |
| chr_1 | g10786 | g10786.t2 | exon | g10786.t2.exon3 | 11974265 | 11975795 |
| chr_1 | g10786 | g10786.t2 | cds | g10786.t2.CDS3 | 11974265 | 11975795 |
| chr_1 | g10786 | g10786.t2 | exon | g10786.t2.exon4 | 11975853 | 11975898 |
| chr_1 | g10786 | g10786.t2 | cds | g10786.t2.CDS4 | 11975853 | 11975898 |
| chr_1 | g10786 | g10786.t2 | TSS | g10786.t2 | 11976738 | 11976738 |
| chr_1 | g10786 | g10786.t2 | TTS | g10786.t2 | NA | NA |
Sequences
>g10786.t2 Gene=g10786 Length=2424
ATGGAGTCAAATAAACATATGTACAGTTACATCGAAATTATTCCAAATCTTTTAGTCTTT
GTAACATTTAAACGAGATTTGAAGCCACTATCGAACAAGCATCGCACGTATATTCGTGTT
GATAATTTTCTTCATTATGAGGGTTTTTATAATGATTTTGGCCCTTACAATATTTGCAAT
TTATATCACTACTGCAAGTATTTAAATATGGAGTTAGAAGCAGCTCGCAAAGCAAATCGT
CTTGTTATACAATACACATGGATGGACAAAGAGAAGCGTTTAAATTCAGCCTACGCTATT
GGCTCATATGCCATCATTTATCTCAACAAAACAGCCGATGATGTTTATAAATTGCTGACT
AACAATGAAACACAAACTTACACAAAATTCAATGATGCATCCGCTGTGTTGAGTGAATAC
AAGCTAACATTGCTTGATTGTTTACGAGCCATAGAAAAAGCTTACAAATTTGGCTTTTTC
AACTTTGATGACTTCAATTATTTAGAGTACGAGCATTATGAAATTGTAGAGAGTGGTGAT
TTAAACTGGATTGTGCCCAATAAGTTCATAGCATTTTGTGGACCACATTTATTATCAGGT
ACAGATAACAAAGGATATACACATCATGCACCTGACAAATATTTCGAGTACTTCCATAAG
AATAATGTGAAAACAATCATAAGGCTCAACTATAAATTTTATGAAGCATCAAGCTTCACA
GATGCGGGTTTTAAGCATTATGATTTAATTTTTCGCGATGGCTCAACCCCGAGTGATACA
ATTATGAATCAATTCCTTGATATTTGTGAGAAAACTGATGGTGCGATTGCGGTTCATTGT
AAAGCTGGTTTAGGCAGAACTGGTAGTTTGATTGGTACTTATATCATGAAACATTATCGA
TTTACTGCTATGGAAGCAATTGCTTGGATTCGACTGTGTCGGCCTGGTAGTGTAATAGGC
CATCAACAACAGTGGATAGAAGAAAAACAACTTCCCATGTGGATACAAGGTGAAGCCTAT
CGTCGTGATAATAAGATTAAATCTATGAAAATCCATGAATTGGGTATATACAGTTACAAA
AATAAAAGTTGTCTTGATGAAGATTTATTAGAGAGCAAAATGATACAAACAGTTGACGAT
ATTGATGGTGATGTTGATGAGACAGAAGATGATGACACAACTACCGAAAATGTTGACGAA
ATAATTGGTGAGATTCAAGAGAAAAATATTAAAAAACGTTCACGATCAGTTACAGGCATC
TCAGAGAAAGTAGATACAATGAAATTGCATGATGATGCTAATGGAAATGTGATGCAAGAA
TCAAAGACAAATGATAAGAACGGCAATATCATTACACCAAGTACTTCGGCAATTACTACG
TCAACTACAACAAAAGCGACAAGAAAAATTTCTACTTTAATAAGGAAAATTACACCTGGA
ACTACAAATACGCTTCCAGCGAAACTTCCTTCAGCTATTGATAGCAGCGAACAATTTACA
CAAGGCGATGAATTGAACCAAATCAAGTTTAGACGAGCTGCTAATCACCATCGATCATTG
ACAGCTTCCTCTACACAAACGGACTCGCTGCTAGTTAAGCCACGTTCATATCACAATCGT
GCTAAATCACAGTCTAGCACGCGAACCCTTGACCATGAAGGAGCAAACCCTACAAATATC
GCTAAGCCGATAACACGAGGTGGAAGTGGAAATGCAAGGACGACAATGGGAAACAATACG
ACGTCATCATCGACATCACCAGTTCGTACGGATCCTTTAAGTCATATTCCGACAATTACA
AGCAGCAATAAGCAGTTAATTAAAAGTAAGCAATCAAAAGACGATGTCACGAAGAGAGCA
TCCGTACGACGTGCCACCTTAGGCAGATCGAAGTTATCACGATCACCAGTGAAGCCACTT
ACATGCACTTTAAGCACAGTGTCATCAACAAATCAAACAATAACAACGACCATTGCGAAT
TCACAATCAATTGAAACACATCCAGTCATTTTGGTAAATGAAGATATCATTGGACCAGTG
ACCAGGAGTCGACTGTGTAAATTATGCCCATCATTAGATGATACAAGCCTTGAGACTTTG
CAAAAACGTGGAAAGAGATCACTCAGCAATTCACGATTCTATGAAAAGAAAAATTGTCGT
AACAAGAAACAAATTCTAACGCCAGTCATCACCGGAACATCACTTACAAGAAAGTTAAGA
AAAGAAGCATCATTAGATTCGGCATTAGCTGATGTGGCTACAAGTAACAAGGATGCCAAT
GACAACACTTCCCTCTCAGAGGCTCCTTCACCAATGAAGGAGGCGCCAAAATCAAGACTT
AAGAAGCCATCCATTCGGTCATCGTCGTCGTCACAAAAAATACTCGCGGTCACAAATACA
GTCACGACAACGAGTGCAAATTGA
>g10786.t2 Gene=g10786 Length=807
MESNKHMYSYIEIIPNLLVFVTFKRDLKPLSNKHRTYIRVDNFLHYEGFYNDFGPYNICN
LYHYCKYLNMELEAARKANRLVIQYTWMDKEKRLNSAYAIGSYAIIYLNKTADDVYKLLT
NNETQTYTKFNDASAVLSEYKLTLLDCLRAIEKAYKFGFFNFDDFNYLEYEHYEIVESGD
LNWIVPNKFIAFCGPHLLSGTDNKGYTHHAPDKYFEYFHKNNVKTIIRLNYKFYEASSFT
DAGFKHYDLIFRDGSTPSDTIMNQFLDICEKTDGAIAVHCKAGLGRTGSLIGTYIMKHYR
FTAMEAIAWIRLCRPGSVIGHQQQWIEEKQLPMWIQGEAYRRDNKIKSMKIHELGIYSYK
NKSCLDEDLLESKMIQTVDDIDGDVDETEDDDTTTENVDEIIGEIQEKNIKKRSRSVTGI
SEKVDTMKLHDDANGNVMQESKTNDKNGNIITPSTSAITTSTTTKATRKISTLIRKITPG
TTNTLPAKLPSAIDSSEQFTQGDELNQIKFRRAANHHRSLTASSTQTDSLLVKPRSYHNR
AKSQSSTRTLDHEGANPTNIAKPITRGGSGNARTTMGNNTTSSSTSPVRTDPLSHIPTIT
SSNKQLIKSKQSKDDVTKRASVRRATLGRSKLSRSPVKPLTCTLSTVSSTNQTITTTIAN
SQSIETHPVILVNEDIIGPVTRSRLCKLCPSLDDTSLETLQKRGKRSLSNSRFYEKKNCR
NKKQILTPVITGTSLTRKLRKEASLDSALADVATSNKDANDNTSLSEAPSPMKEAPKSRL
KKPSIRSSSSSQKILAVTNTVTTTSAN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 9 | g10786.t2 | CDD | cd17657 | CDC14_N | 9 | 154 | 4.48578E-47 |
| 10 | g10786.t2 | CDD | cd14499 | CDC14_C | 169 | 338 | 6.7334E-115 |
| 7 | g10786.t2 | Gene3D | G3DSA:3.90.190.10 | Protein tyrosine phosphatase superfamily | 3 | 155 | 1.1E-40 |
| 8 | g10786.t2 | Gene3D | G3DSA:3.90.190.10 | Protein tyrosine phosphatase superfamily | 176 | 345 | 3.5E-57 |
| 17 | g10786.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 516 | 635 | - |
| 14 | g10786.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 517 | 554 | - |
| 18 | g10786.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 562 | 607 | - |
| 16 | g10786.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 608 | 622 | - |
| 15 | g10786.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 756 | 793 | - |
| 3 | g10786.t2 | PANTHER | PTHR23339:SF27 | CELL DIVISION CYCLE 14, ISOFORM A | 10 | 621 | 6.7E-154 |
| 4 | g10786.t2 | PANTHER | PTHR23339 | TYROSINE SPECIFIC PROTEIN PHOSPHATASE AND DUAL SPECIFICITY PROTEIN PHOSPHATASE | 10 | 621 | 6.7E-154 |
| 2 | g10786.t2 | Pfam | PF14671 | Dual specificity protein phosphatase, N-terminal half | 12 | 154 | 5.7E-40 |
| 1 | g10786.t2 | Pfam | PF00782 | Dual specificity phosphatase, catalytic domain | 260 | 319 | 5.2E-12 |
| 11 | g10786.t2 | ProSitePatterns | PS00383 | Tyrosine specific protein phosphatases active site. | 278 | 288 | - |
| 19 | g10786.t2 | ProSiteProfiles | PS50056 | Tyrosine specific protein phosphatases family profile. | 263 | 325 | 15.859 |
| 13 | g10786.t2 | SMART | SM00195 | dsp_5 | 180 | 332 | 0.0051 |
| 12 | g10786.t2 | SMART | SM00404 | ptp_7 | 240 | 333 | 0.0034 |
| 5 | g10786.t2 | SUPERFAMILY | SSF52799 | (Phosphotyrosine protein) phosphatases II | 6 | 163 | 4.59E-31 |
| 6 | g10786.t2 | SUPERFAMILY | SSF52799 | (Phosphotyrosine protein) phosphatases II | 170 | 327 | 9.66E-39 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008138 | protein tyrosine/serine/threonine phosphatase activity | MF |
| GO:0004721 | phosphoprotein phosphatase activity | MF |
| GO:0007096 | regulation of exit from mitosis | BP |
| GO:0006470 | protein dephosphorylation | BP |
| GO:0016311 | dephosphorylation | BP |
| GO:0004725 | protein tyrosine phosphatase activity | MF |
| GO:0016791 | phosphatase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K06639 (cell division cycle 14)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
