General information for g10842.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Kynurenine–oxoglutarate transaminase 3.
Parent gene
- The parent gene g10842 is located on chr_1: 12219351..12220534 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10842 | g10842.t1 | TTS | g10842.t1 | 12218402 | 12218402 |
| chr_1 | g10842 | g10842.t1 | isoform | g10842.t1 | 12218757 | 12220177 |
| chr_1 | g10842 | g10842.t1 | exon | g10842.t1.exon1 | 12218757 | 12219960 |
| chr_1 | g10842 | g10842.t1 | cds | g10842.t1.CDS1 | 12218757 | 12219960 |
| chr_1 | g10842 | g10842.t1 | exon | g10842.t1.exon2 | 12220023 | 12220177 |
| chr_1 | g10842 | g10842.t1 | cds | g10842.t1.CDS2 | 12220023 | 12220177 |
| chr_1 | g10842 | g10842.t1 | TSS | g10842.t1 | 12220463 | 12220463 |
Sequences
>g10842.t1 Gene=g10842 Length=1359
ATGTTGATTAAATCTGCTTTTAATCAATTAAGAATTTGTCAACATATTTCTAGATCGTGC
TTTATTAGTCCTCATCGATTCATGGCATCCACTACTGCTGGCAGTGAAAAATTTGGTCTT
CCTAAAAGATATCAGGAAGCATCAGAAAGTGTTTGGGTCGAATATGTAGCACTTGCGCTC
AAATATAAACCACTAAACTTAGGTCAGGGTTTTCCAGATTATCCACCACCATCTTATGTC
ACAAAGGCATTATCAGATGTGGCGAATGGAGATCATTTGCTTAATCAATATACTAGGGGC
TTTGGTCATCCTCGACTAGTTAATGCTCTTGCAAAAGTTTATGGTCAATTGATTAATCGA
GAAATTGATCCATTCAATGAAATACTTGTAACCGTTGGTGCTTATCAATCACTTTACAAT
GCAATTTACGGTCATGTTGATCATGGCGATGAAGTCATTATTATCGAACCATTTTACGAC
TGTTATTATGATATGATTAAATCAGCAGGAGGTATTGTAAAAGCAATCGCATTGAAACCG
ACAAAGACTGGTGTAATCAGCTCAGCTGATTGGAAACTTGATCCCAAAGAATTAGAGTCA
CTCTTCAATGAGAAAACTAAAATGATCATTTTAAACACACCGCACAATCCTCTTGGAAAA
GTTTTTAATATAGAAGAACTGACATTGATTGCTGATTTATGCAAAAAATGGAATGTAATG
GTTGTAGCAGATGAAGTTTATGAGCATATGGTGTTTGAGCCAAATAAGCACATTCGTATT
TGCACACTTCCTGGAATGTGGGAACGTACAATTACAATTGGCAGTGCGGGTAAAACGTTT
TCTGCGACAGGATGGAAATTAGGATGGAGTTATGGGCCAAATAATTTGATTCGAAATATG
CAACTTGTTCATCAAAACTCTGTTTATACTTGTGCAACACCACTTCAAGAAGCAGCCGCT
ATTGGATTTGAATATGAATTAAGCAGATTTAATTCAAGCGAATCATTTTTCAAATCTCTG
GCTGTTGAATTGAAAGGAAAACGAGACTTTATGGCAAATTTTCTTGTTCAAAATGGATTT
GAGCCGACTATTCCAGAGGCTGGATATTTTATGATTGCTGATTGGACTCATCTTGCAAAT
AAGGTTGATTTATCATCTGAGACTGATGAATATAAAGACTATCGCTTCACTAAATGGATG
ACTAAGAACATCTCTTTGCAAGGAATACCTCCCTCAGCTTTCTATACTAAACCGCATAAG
CATTTGGGGGAAAATTTTGTCAGATATTGTTATATAAAGAAAGATGAGACATTACAAAAA
GCTGCTGATATCTTGAAACAATGGTACAACAAAAATTAA
>g10842.t1 Gene=g10842 Length=452
MLIKSAFNQLRICQHISRSCFISPHRFMASTTAGSEKFGLPKRYQEASESVWVEYVALAL
KYKPLNLGQGFPDYPPPSYVTKALSDVANGDHLLNQYTRGFGHPRLVNALAKVYGQLINR
EIDPFNEILVTVGAYQSLYNAIYGHVDHGDEVIIIEPFYDCYYDMIKSAGGIVKAIALKP
TKTGVISSADWKLDPKELESLFNEKTKMIILNTPHNPLGKVFNIEELTLIADLCKKWNVM
VVADEVYEHMVFEPNKHIRICTLPGMWERTITIGSAGKTFSATGWKLGWSYGPNNLIRNM
QLVHQNSVYTCATPLQEAAAIGFEYELSRFNSSESFFKSLAVELKGKRDFMANFLVQNGF
EPTIPEAGYFMIADWTHLANKVDLSSETDEYKDYRFTKWMTKNISLQGIPPSAFYTKPHK
HLGENFVRYCYIKKDETLQKAADILKQWYNKN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g10842.t1 | CDD | cd00609 | AAT_like | 65 | 447 | 0 |
| 5 | g10842.t1 | Gene3D | G3DSA:3.90.1150.10 | Aspartate Aminotransferase | 50 | 445 | 0 |
| 6 | g10842.t1 | Gene3D | G3DSA:3.40.640.10 | - | 78 | 332 | 0 |
| 2 | g10842.t1 | PANTHER | PTHR43807:SF6 | KYNURENINE–OXOGLUTARATE TRANSAMINASE 3 | 28 | 450 | 0 |
| 3 | g10842.t1 | PANTHER | PTHR43807 | FI04487P | 28 | 450 | 0 |
| 1 | g10842.t1 | Pfam | PF00155 | Aminotransferase class I and II | 64 | 443 | 0 |
| 4 | g10842.t1 | SUPERFAMILY | SSF53383 | PLP-dependent transferases | 40 | 450 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0009058 | biosynthetic process | BP |
| GO:0036137 | kynurenine aminotransferase activity | MF |
| GO:0006520 | cellular amino acid metabolic process | BP |
| GO:0070189 | kynurenine metabolic process | BP |
| GO:0003824 | catalytic activity | MF |
| GO:0030170 | pyridoxal phosphate binding | MF |
KEGG
Orthology
- This transcript has been annotated with K00816 (kynurenine—oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine—phenylpyruvate transaminase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
