Gene loci information

Transcript annotation

  • This transcript has been annotated as Pantothenate kinase 1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g10929 g10929.t1 isoform g10929.t1 12824525 12829576
chr_1 g10929 g10929.t1 exon g10929.t1.exon1 12824525 12824915
chr_1 g10929 g10929.t1 cds g10929.t1.CDS1 12824525 12824915
chr_1 g10929 g10929.t1 exon g10929.t1.exon2 12827081 12827256
chr_1 g10929 g10929.t1 cds g10929.t1.CDS2 12827081 12827256
chr_1 g10929 g10929.t1 exon g10929.t1.exon3 12827833 12827935
chr_1 g10929 g10929.t1 cds g10929.t1.CDS3 12827833 12827935
chr_1 g10929 g10929.t1 exon g10929.t1.exon4 12828013 12828083
chr_1 g10929 g10929.t1 cds g10929.t1.CDS4 12828013 12828083
chr_1 g10929 g10929.t1 exon g10929.t1.exon5 12828146 12828264
chr_1 g10929 g10929.t1 cds g10929.t1.CDS5 12828146 12828264
chr_1 g10929 g10929.t1 exon g10929.t1.exon6 12828415 12828605
chr_1 g10929 g10929.t1 cds g10929.t1.CDS6 12828415 12828605
chr_1 g10929 g10929.t1 exon g10929.t1.exon7 12828691 12828807
chr_1 g10929 g10929.t1 cds g10929.t1.CDS7 12828691 12828807
chr_1 g10929 g10929.t1 exon g10929.t1.exon8 12828973 12829023
chr_1 g10929 g10929.t1 cds g10929.t1.CDS8 12828973 12829023
chr_1 g10929 g10929.t1 exon g10929.t1.exon9 12829174 12829253
chr_1 g10929 g10929.t1 cds g10929.t1.CDS9 12829174 12829253
chr_1 g10929 g10929.t1 exon g10929.t1.exon10 12829367 12829481
chr_1 g10929 g10929.t1 cds g10929.t1.CDS10 12829367 12829481
chr_1 g10929 g10929.t1 exon g10929.t1.exon11 12829539 12829576
chr_1 g10929 g10929.t1 cds g10929.t1.CDS11 12829539 12829576
chr_1 g10929 g10929.t1 TTS g10929.t1 12829988 12829988
chr_1 g10929 g10929.t1 TSS g10929.t1 NA NA

Sequences

>g10929.t1 Gene=g10929 Length=1452
ATGGCTTCATTGTATGTAAAATATCCAAAAACCTGCCGCAATAAAAAGTCTAGTGTCTAT
CTGACACCACCTGTCTCATCGATCTCATCATCTTCATCAGGCTCATTGTCGAGCGCTGAT
GGTATTAAGCCAGCTTCATTAATCAATTCTCAAAAATCATCAAAACGTAAACAACATTAT
TATCCTCACCATCATCATATGAGAAGTCACAAGGTCTCGACAATGCCAAAACGTCGAAAA
TTAAAGCTTAAAAAATCATCAGCTTCATCGTCTGCTGCAGCGACAAGCAGTGACAGCGAC
ACAAACAAACTCAATGAATGCCGGTCGTTCATCAACAATAATGCTCAAGAAGAAATCAAC
CGAAATAATTGTGACTGTGACTTTCAAACATTACCAGCAATTGGAGTCGATGTAGGTGGG
ACGTTAACCAAATTAGTTTATTTTGAACCAAATGACGAAGAAGAATATGGTGGAGAATTG
GAAGCAAAAGTACTCAAAAACATTCGTAGATATTTGACGAAAAATTCAGCTTATGGAAAT
ACAGGTCATCGCGATATACATTTACAGATGAACAATGTGGAGATTCATAATAAGAAGGGT
ACACTGCACTTTATTAGATTTCCCACAGCGGAGATGAGTTCATTTCTGCAATTGGCAAAG
TCAAAAGGAATGGCGATGCTTCTGACAACTGTTTGTGCAACTGGCGGTGGTGCTTTCAAA
TTTGAGGAAGAATTTAGAAGGGAAGTGAATATTCGACTGAAGAAATTCGATGAACTAGAT
GCACTTATTAAAGGAATATTGTATGCAGATATTCACAATAGAAGCGAATGTTATTACTAT
GAGAATGCAAGTGATATTAGTATAAGTCAAAAGGCACGATTTGATTTCTCTCAACCGTAT
CCATTTATACTTGTTAACATTGGCAGTGGTGTGAGTATTTTGGCAGTAAGGGGTGCAAAC
GATTACAAGCGAATATCTGGTACATCGTTAGGTGGCGGAACATTCCTTGGACTTTGTAGT
CTACTCACTGGATGTACGACATTTGAAGAAGCAATCCAACTAGCGACAAAAGGTGATCAC
ACGAAAGTGGATAAATTAGTTAGAGATATTTATGGAGGTGATTATGAGAGATTTGGCCTT
CCTGGTAGTCTCGTTGCATCAAGTTTTGGTCAAATGAATTCGAGAGAACGTAGGGCGAGT
GTTTCAAAGGAAGACTTAGCAAATGCCACTTTAGTAACAATCACGAACAATATTGGTTTG
ATTGCTAGAATGTGCGCAGTGAATGAAAAAATTGATAAGGTCGTCTTTGTTGGAAATTTT
TTGCGTGTGAATCCAATCAGTATGAAATTACTTGCATATGCTATGGACTATTGGAGTAAT
CATACATTAAAAGCTCTTTTTCTTGAGCATGAAGGTTATTTTGGTGCAATCGGAACTTTA
CTTCTAGCATAA

>g10929.t1 Gene=g10929 Length=483
MASLYVKYPKTCRNKKSSVYLTPPVSSISSSSSGSLSSADGIKPASLINSQKSSKRKQHY
YPHHHHMRSHKVSTMPKRRKLKLKKSSASSSAAATSSDSDTNKLNECRSFINNNAQEEIN
RNNCDCDFQTLPAIGVDVGGTLTKLVYFEPNDEEEYGGELEAKVLKNIRRYLTKNSAYGN
TGHRDIHLQMNNVEIHNKKGTLHFIRFPTAEMSSFLQLAKSKGMAMLLTTVCATGGGAFK
FEEEFRREVNIRLKKFDELDALIKGILYADIHNRSECYYYENASDISISQKARFDFSQPY
PFILVNIGSGVSILAVRGANDYKRISGTSLGGGTFLGLCSLLTGCTTFEEAIQLATKGDH
TKVDKLVRDIYGGDYERFGLPGSLVASSFGQMNSRERRASVSKEDLANATLVTITNNIGL
IARMCAVNEKIDKVVFVGNFLRVNPISMKLLAYAMDYWSNHTLKALFLEHEGYFGAIGTL
LLA

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g10929.t1 Gene3D G3DSA:3.30.420.510 - 134 481 1.2E-153
10 g10929.t1 Gene3D G3DSA:3.30.420.40 - 276 473 1.2E-153
9 g10929.t1 Gene3D G3DSA:1.10.8.780 - 360 402 1.2E-153
6 g10929.t1 MobiDBLite mobidb-lite consensus disorder prediction 46 99 -
7 g10929.t1 MobiDBLite mobidb-lite consensus disorder prediction 56 85 -
2 g10929.t1 PANTHER PTHR12280:SF30 FUMBLE 99 481 3.3E-180
3 g10929.t1 PANTHER PTHR12280 PANTOTHENATE KINASE 99 481 3.3E-180
1 g10929.t1 Pfam PF03630 Fumble 134 481 3.9E-115
4 g10929.t1 SUPERFAMILY SSF53067 Actin-like ATPase domain 132 268 2.14E-39
5 g10929.t1 SUPERFAMILY SSF53067 Actin-like ATPase domain 249 482 2.05E-72
11 g10929.t1 TIGRFAM TIGR00555 panK_eukar: pantothenate kinase 133 481 1.4E-112

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005524 ATP binding MF
GO:0004594 pantothenate kinase activity MF
GO:0015937 coenzyme A biosynthetic process BP

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values