Gene loci information

Transcript annotation

  • This transcript has been annotated as Pantothenate kinase 1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g10929 g10929.t3 isoform g10929.t3 12821085 12829980
chr_1 g10929 g10929.t3 exon g10929.t3.exon1 12821085 12821328
chr_1 g10929 g10929.t3 TSS g10929.t3 12821109 12821109
chr_1 g10929 g10929.t3 exon g10929.t3.exon2 12826604 12826702
chr_1 g10929 g10929.t3 exon g10929.t3.exon3 12827081 12827256
chr_1 g10929 g10929.t3 exon g10929.t3.exon4 12827833 12827935
chr_1 g10929 g10929.t3 exon g10929.t3.exon5 12827988 12828083
chr_1 g10929 g10929.t3 cds g10929.t3.CDS1 12828018 12828083
chr_1 g10929 g10929.t3 exon g10929.t3.exon6 12828146 12828264
chr_1 g10929 g10929.t3 cds g10929.t3.CDS2 12828146 12828264
chr_1 g10929 g10929.t3 exon g10929.t3.exon7 12828415 12828605
chr_1 g10929 g10929.t3 cds g10929.t3.CDS3 12828415 12828605
chr_1 g10929 g10929.t3 exon g10929.t3.exon8 12828691 12828807
chr_1 g10929 g10929.t3 cds g10929.t3.CDS4 12828691 12828807
chr_1 g10929 g10929.t3 exon g10929.t3.exon9 12828973 12829023
chr_1 g10929 g10929.t3 cds g10929.t3.CDS5 12828973 12829023
chr_1 g10929 g10929.t3 exon g10929.t3.exon10 12829174 12829253
chr_1 g10929 g10929.t3 cds g10929.t3.CDS6 12829174 12829253
chr_1 g10929 g10929.t3 exon g10929.t3.exon11 12829367 12829481
chr_1 g10929 g10929.t3 cds g10929.t3.CDS7 12829367 12829481
chr_1 g10929 g10929.t3 exon g10929.t3.exon12 12829539 12829980
chr_1 g10929 g10929.t3 cds g10929.t3.CDS8 12829539 12829576
chr_1 g10929 g10929.t3 TTS g10929.t3 12829988 12829988

Sequences

>g10929.t3 Gene=g10929 Length=1833
TCTACAAAAATATGTAATAAATACAAAAGTCTACAAAAATCGTGTTGTCGAAGTAAAACA
AATTTAAAAACTTGAATTATAATGCTAAATAGAATAAGAATATTGTCGTAAATAAATTAA
AAGTGATTGAATAATAATACTAAATTGATTAAACCATAAGATATAATGGAAGCAAGGTGC
GATTTAGAAAAAGAAGCTGAAACTGATAAATTAAAAGAGGATTTCGATAGTGTAAATAAT
TCTGCTGCTTTGAATTTATGTAATGTACAAAGTCTTCAAAACGATATCGATCATTGCTCG
AATAATTTAGAAAATTCCGATCAGCCGCATCCGCATTTGCCAGTACCAGCAATTGGAGTC
GATGTAGGTGGGACGTTAACCAAATTAGTTTATTTTGAACCAAATGACGAAGAAGAATAT
GGTGGAGAATTGGAAGCAAAAGTACTCAAAAACATTCGTAGATATTTGACGAAAAATTCA
GCTTATGGAAATACAGGTCATCGCGATATACATTTACAGATGAACAATGTGGAGATTCAT
AATAAGAAGGGTACACTGCACTTTATTAGATTTCCCACAGCGGAGATGAGTTCATTTCTG
CAATTGGCAAAGTCAAAAGGAATCCCTCTTGTGTCTGTCTCAAACAGTGGCGATGCTTCT
GACAACTGTTTGTGCAACTGGCGGTGGTGCTTTCAAATTTGAGGAAGAATTTAGAAGGGA
AGTGAATATTCGACTGAAGAAATTCGATGAACTAGATGCACTTATTAAAGGAATATTGTA
TGCAGATATTCACAATAGAAGCGAATGTTATTACTATGAGAATGCAAGTGATATTAGTAT
AAGTCAAAAGGCACGATTTGATTTCTCTCAACCGTATCCATTTATACTTGTTAACATTGG
CAGTGGTGTGAGTATTTTGGCAGTAAGGGGTGCAAACGATTACAAGCGAATATCTGGTAC
ATCGTTAGGTGGCGGAACATTCCTTGGACTTTGTAGTCTACTCACTGGATGTACGACATT
TGAAGAAGCAATCCAACTAGCGACAAAAGGTGATCACACGAAAGTGGATAAATTAGTTAG
AGATATTTATGGAGGTGATTATGAGAGATTTGGCCTTCCTGGTAGTCTCGTTGCATCAAG
TTTTGGTCAAATGAATTCGAGAGAACGTAGGGCGAGTGTTTCAAAGGAAGACTTAGCAAA
TGCCACTTTAGTAACAATCACGAACAATATTGGTTTGATTGCTAGAATGTGCGCAGTGAA
TGAAAAAATTGATAAGGTCGTCTTTGTTGGAAATTTTTTGCGTGTGAATCCAATCAGTAT
GAAATTACTTGCATATGCTATGGACTATTGGAGTAATCATACATTAAAAGCTCTTTTTCT
TGAGCATGAAGGTTATTTTGGTGCAATCGGAACTTTACTTCTAGCATAAAAGGAGTAATG
AATTTAAACTTCATTTAATTCAACGCGTATGAAGCAGCAGCAGTAATATCTACCTATTTA
TAAAAAACCATTTAGAATATCGCTACATTTAAGGGCATTTTTTATACGATTTTTGGAAAA
TTTATTGCGAGAATGATGTTAACGATGCGCAAATTTGTGGGGGTCTTTCAGTAATCAATT
TGATTTTTTTCTTCGTTTTATTTTAGTTAGGTAGTTTAAAAAAGGACAAAAATGACTTTT
ATATGTTCACCAACTTTTTTTCTCAAATGATAAATTTCTGTTTTAAGTTACTTAATAGTT
AAGTGAATGATATTAGCTTCTACAGAGCTATAAATGACGATTATAGAAAAAACCTTTTTT
CATTATACGATTTGAATAAAATTTTAAACAAAA

>g10929.t3 Gene=g10929 Length=258
MLLTTVCATGGGAFKFEEEFRREVNIRLKKFDELDALIKGILYADIHNRSECYYYENASD
ISISQKARFDFSQPYPFILVNIGSGVSILAVRGANDYKRISGTSLGGGTFLGLCSLLTGC
TTFEEAIQLATKGDHTKVDKLVRDIYGGDYERFGLPGSLVASSFGQMNSRERRASVSKED
LANATLVTITNNIGLIARMCAVNEKIDKVVFVGNFLRVNPISMKLLAYAMDYWSNHTLKA
LFLEHEGYFGAIGTLLLA

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g10929.t3 Gene3D G3DSA:3.30.420.510 - 1 61 0.0
6 g10929.t3 Gene3D G3DSA:3.30.420.40 - 62 239 0.0
2 g10929.t3 PANTHER PTHR12280:SF30 FUMBLE 3 256 0.0
3 g10929.t3 PANTHER PTHR12280 PANTOTHENATE KINASE 3 256 0.0
8 g10929.t3 PIRSF PIRSF036940 PanK_bac_aCoA 2 59 7.2
9 g10929.t3 PIRSF PIRSF036940 PanK_bac_aCoA 61 258 0.0
1 g10929.t3 Pfam PF03630 Fumble 5 256 0.0
4 g10929.t3 SUPERFAMILY SSF53067 Actin-like ATPase domain 24 257 0.0
7 g10929.t3 TIGRFAM TIGR00555 panK_eukar: pantothenate kinase 3 256 0.0

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0005524 ATP binding MF
GO:0004594 pantothenate kinase activity MF
GO:0015937 coenzyme A biosynthetic process BP

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values