General information for g10980.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Dihydropyrimidinase-related protein 2.
Parent gene
- The parent gene g10980 is located on chr_1: 13116202..13117650 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g10980 | g10980.t1 | TTS | g10980.t1 | 13114933 | 13114933 |
| chr_1 | g10980 | g10980.t1 | isoform | g10980.t1 | 13115184 | 13117650 |
| chr_1 | g10980 | g10980.t1 | exon | g10980.t1.exon1 | 13115184 | 13115260 |
| chr_1 | g10980 | g10980.t1 | cds | g10980.t1.CDS1 | 13115184 | 13115260 |
| chr_1 | g10980 | g10980.t1 | exon | g10980.t1.exon2 | 13115318 | 13115994 |
| chr_1 | g10980 | g10980.t1 | cds | g10980.t1.CDS2 | 13115318 | 13115994 |
| chr_1 | g10980 | g10980.t1 | exon | g10980.t1.exon3 | 13116058 | 13116582 |
| chr_1 | g10980 | g10980.t1 | cds | g10980.t1.CDS3 | 13116058 | 13116582 |
| chr_1 | g10980 | g10980.t1 | exon | g10980.t1.exon4 | 13116655 | 13117058 |
| chr_1 | g10980 | g10980.t1 | cds | g10980.t1.CDS4 | 13116655 | 13117058 |
| chr_1 | g10980 | g10980.t1 | exon | g10980.t1.exon5 | 13117606 | 13117650 |
| chr_1 | g10980 | g10980.t1 | cds | g10980.t1.CDS5 | 13117606 | 13117650 |
| chr_1 | g10980 | g10980.t1 | TSS | g10980.t1 | NA | NA |
Sequences
>g10980.t1 Gene=g10980 Length=1728
ATGGACGCCCCAAAGCCAGTTAAGAAAATTCCAATTCACGTTCAGAGCTCGCAAAATAGG
CTCTACATAAAGCGGGCACGAGTAGTAAATCATGATTCGATATTGACAAACGTTGACATT
TACATTGAAGACGGAACGATCAAGTTCATCGGCAGCCCAGCAGACTTTGTAGTTCCTGGC
GGTGTGCGAGTAATTGATGTTGCAGGAAAATATGTTTTCCCAGGTGGCATTGATCCTAAT
ACTCAATTTGAAAGCGAATCGAATGGATTTGTATCCGCAGACACTTTTTATAGTGGAACA
AAAGCTGCAGTTGCAGGTGGTACCACTTGCATCATTGATTTGATTTTACCAAATCCTGGT
GAATCATTGATTGAAGCATGCAATACATGGCGTACAAAAGCTGATGGAAAAGTTGTTGCT
GATTATGCTCTTCGCTGTGCAATTACAAGCTGGAATAAATCCGTTAGCGATGAAATGAAA
ACGCTATGTGAAGAGTTTGGAATAAATTGCTTCGTTGTGTTTATGGCATTCAAAGATCAA
TATCAGTTGAGTGATTCCGATTTATATGAGATTTTTGAAAGATGCAATGAGCTTGGTGCA
TTATGTCAAGTGCATGCTGAGAATGGTGATATCATTGCGAAAAATGTTGAGAAACTTGTT
GCAAAAGGTCAAACAAGTGCAGAAGCACATGATCTCTCAAGAAGTGCAGAAGTTGAAGCG
GAAGCAGTTAATCGTGCATGTGTAATCGCTCATCAAACTGATTCACCAATTTATATCACC
AAAGTTTCTTCCAAATTGGCTGCCGATCAAATTCAACTTGCAAAACGCAGAGGAACAAAA
GTTTATGGTGAGATTTTAGCTGCCTCTATTGGGTGCAACACTCCAGCTGCTCCATCCATT
TACACTCTTACATCTCCACCATTGAGATTGAAAGATCCAGAAAATTCTAAATTACTTCTT
AAACATGTTGCACTTGATGATATTCAAGTTGTAGCAAGTGGAAATTGTTCATTTACAAGA
GCTCAAAAGGAAGAAAACAAAAGTGACTTTACAAAAGTACCAAATGGTGTGAACGGAGCA
GAAGATCGTTTGAAAATTGTTTGGGAAAAATGTGTCGTTCCAAGCTTGATTGATCTTCAA
AAATTTGTTGCAATCACATCTACAAATGCGGCAAAAATTTTCAATCTTTATCCTAAGAAA
GGAAGTTTGACAGTTGGTTCTGATGCTGACATTTTGATTTGGAATCATCAAGCAAATAAG
ACAATTTCATCTAAAACTCATAGTCATGCAAGTGATTACAATATTTTCGAAGGTGTCAAA
GTCAGTGGTGCACCAGAATTTGTAATTGTGAAAGGAAAAGTATGCTATGAAGATGATAAT
CCACGTGTAGCAGAAGGATTTGGAAACTATATTGAATTGAGTCCATATTCACAATTGCTT
TATGGCACAAAGAATGGAGATGATTTGTCAGATAAATTTGAGGATTGCATTCAACTTGAT
CAATTTCAAGAAGAGTTTGAAGACAGAGATTATGTCCCAGAAAAAGCAGAATCAATTGTT
AGTACATCAACTCAGGTTACACACACTGCCCGTGCAATGCGACAAGAAGGTCAACGTGAT
CTTCAAGCATCTTCATTCTCCATATCTAAAGAAATATGCAATGAACCCAATAAAGCGTGC
ATTAGAGTTAGAGCGCCTCCAGGAGGCAAATCATCAGGCTTGTGGTAA
>g10980.t1 Gene=g10980 Length=575
MDAPKPVKKIPIHVQSSQNRLYIKRARVVNHDSILTNVDIYIEDGTIKFIGSPADFVVPG
GVRVIDVAGKYVFPGGIDPNTQFESESNGFVSADTFYSGTKAAVAGGTTCIIDLILPNPG
ESLIEACNTWRTKADGKVVADYALRCAITSWNKSVSDEMKTLCEEFGINCFVVFMAFKDQ
YQLSDSDLYEIFERCNELGALCQVHAENGDIIAKNVEKLVAKGQTSAEAHDLSRSAEVEA
EAVNRACVIAHQTDSPIYITKVSSKLAADQIQLAKRRGTKVYGEILAASIGCNTPAAPSI
YTLTSPPLRLKDPENSKLLLKHVALDDIQVVASGNCSFTRAQKEENKSDFTKVPNGVNGA
EDRLKIVWEKCVVPSLIDLQKFVAITSTNAAKIFNLYPKKGSLTVGSDADILIWNHQANK
TISSKTHSHASDYNIFEGVKVSGAPEFVIVKGKVCYEDDNPRVAEGFGNYIELSPYSQLL
YGTKNGDDLSDKFEDCIQLDQFQEEFEDRDYVPEKAESIVSTSTQVTHTARAMRQEGQRD
LQASSFSISKEICNEPNKACIRVRAPPGGKSSGLW
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g10980.t1 | CDD | cd01314 | D-HYD | 21 | 468 | 0 |
| 7 | g10980.t1 | Gene3D | G3DSA:2.30.40.10 | Urease | 21 | 482 | 0 |
| 8 | g10980.t1 | Gene3D | G3DSA:3.20.20.140 | - | 75 | 442 | 0 |
| 3 | g10980.t1 | PANTHER | PTHR11647 | HYDRANTOINASE/DIHYDROPYRIMIDINASE FAMILY MEMBER | 9 | 484 | 0 |
| 1 | g10980.t1 | Pfam | PF01979 | Amidohydrolase family | 71 | 253 | 0 |
| 2 | g10980.t1 | Pfam | PF01979 | Amidohydrolase family | 377 | 454 | 0 |
| 6 | g10980.t1 | SUPERFAMILY | SSF51338 | Composite domain of metallo-dependent hydrolases | 20 | 83 | 0 |
| 4 | g10980.t1 | SUPERFAMILY | SSF51556 | Metallo-dependent hydrolases | 75 | 401 | 0 |
| 5 | g10980.t1 | SUPERFAMILY | SSF51338 | Composite domain of metallo-dependent hydrolases | 378 | 477 | 0 |
| 9 | g10980.t1 | TIGRFAM | TIGR02033 | D-hydantoinase: dihydropyrimidinase | 22 | 472 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016787 | hydrolase activity | MF |
| GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | MF |
| GO:0005737 | cytoplasm | CC |
KEGG
Orthology
- This transcript has been annotated with K01464 (dihydropyrimidinase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
