General information for g11032.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Dopamine D2-like receptor.
Parent gene
- The parent gene g11032 is located on chr_1: 13556548..13569732 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11032 | g11032.t1 | isoform | g11032.t1 | 13524655 | 13569732 |
| chr_1 | g11032 | g11032.t1 | exon | g11032.t1.exon1 | 13524655 | 13525246 |
| chr_1 | g11032 | g11032.t1 | cds | g11032.t1.CDS1 | 13524655 | 13525246 |
| chr_1 | g11032 | g11032.t1 | exon | g11032.t1.exon2 | 13526087 | 13526277 |
| chr_1 | g11032 | g11032.t1 | cds | g11032.t1.CDS2 | 13526087 | 13526277 |
| chr_1 | g11032 | g11032.t1 | exon | g11032.t1.exon3 | 13543810 | 13543919 |
| chr_1 | g11032 | g11032.t1 | cds | g11032.t1.CDS3 | 13543810 | 13543919 |
| chr_1 | g11032 | g11032.t1 | exon | g11032.t1.exon4 | 13547139 | 13547391 |
| chr_1 | g11032 | g11032.t1 | cds | g11032.t1.CDS4 | 13547139 | 13547391 |
| chr_1 | g11032 | g11032.t1 | exon | g11032.t1.exon5 | 13556333 | 13556550 |
| chr_1 | g11032 | g11032.t1 | cds | g11032.t1.CDS5 | 13556333 | 13556550 |
| chr_1 | g11032 | g11032.t1 | exon | g11032.t1.exon6 | 13558435 | 13558527 |
| chr_1 | g11032 | g11032.t1 | cds | g11032.t1.CDS6 | 13558435 | 13558527 |
| chr_1 | g11032 | g11032.t1 | exon | g11032.t1.exon7 | 13558718 | 13558978 |
| chr_1 | g11032 | g11032.t1 | cds | g11032.t1.CDS7 | 13558718 | 13558978 |
| chr_1 | g11032 | g11032.t1 | exon | g11032.t1.exon8 | 13559057 | 13559191 |
| chr_1 | g11032 | g11032.t1 | cds | g11032.t1.CDS8 | 13559057 | 13559191 |
| chr_1 | g11032 | g11032.t1 | exon | g11032.t1.exon9 | 13564957 | 13565057 |
| chr_1 | g11032 | g11032.t1 | cds | g11032.t1.CDS9 | 13564957 | 13565057 |
| chr_1 | g11032 | g11032.t1 | exon | g11032.t1.exon10 | 13567405 | 13567525 |
| chr_1 | g11032 | g11032.t1 | cds | g11032.t1.CDS10 | 13567405 | 13567525 |
| chr_1 | g11032 | g11032.t1 | exon | g11032.t1.exon11 | 13567597 | 13567612 |
| chr_1 | g11032 | g11032.t1 | cds | g11032.t1.CDS11 | 13567597 | 13567612 |
| chr_1 | g11032 | g11032.t1 | exon | g11032.t1.exon12 | 13569394 | 13569732 |
| chr_1 | g11032 | g11032.t1 | cds | g11032.t1.CDS12 | 13569394 | 13569732 |
| chr_1 | g11032 | g11032.t1 | TSS | g11032.t1 | NA | NA |
| chr_1 | g11032 | g11032.t1 | TTS | g11032.t1 | NA | NA |
Sequences
>g11032.t1 Gene=g11032 Length=2430
ATGGCTATAAACAATACAAATAACAGTCTTAACTCGAGCGCATTTCACTATTATAAACTG
TACAATGAAAATGCTACAAATTTATCAACCCCTGTCGTCACAACTTCATCTTCATCTTTT
ACACGCGTCACCGCAAATCTCTCACCACCATTGACGCCTTCAACGCCAGTCACGACGACT
ACTCTGCCGCAACTGGCCGCCGCCACTACAATTCACACGATTACATCCACGATAACTAAT
AATTCATTATATAGTCAAAATTATTATAGCAATTACACAAATGATAATAATAATAGCAGC
AGCAGCAGCAGCAGTAGTAGTATAAGCAACTACACATCATCAACATTGAATAGTTTTAAT
CAATCAACGTTATATCAATATAGAAATCTAAGTAGCAACAATAGCGATGAAAATTCTTAC
AATGATAGTGCCAAAATATCATATGAAAGTGGCAGCAACTTTATGTTGTTACTTGAAGAC
TTTGGCGAGTATTTTTACAACTATAATGGAAGCGATTACAATTCATCTATAAGCATCTAT
CAGACTAATTGCTCGCTGACCAATTCTACTTCATGTGGTGATGTTACTGCACCGAATTCC
AATTATTGGGCATTAATATTAGTAATATTTCCATTTCTCACGCTGTTCGGCAATGTGCTC
GTCATATTGTCAGTCTTGCGTGAGAGAACTCTTCAAACTGTTACAAATTATTTCATTGTA
TCATTGGCAATTGCTGATTTACTCGTGGCAGTTGTCGTTATGCCCTTCGGTGTATATTAT
TTGGTAAATGGTGCTTGGTCTTTACCAAATGTAGTATGTGATTTTTATATAGCAATGGAT
GTGATTTGTTCAACATCATCAATATTTAATTTAGTCGCGATATCTATTGACAGATATATA
GCAGTAACGCAACCTATTAAATATGCGAAACATAAAAACAGCCGGAGAGTATGTCTCACG
ATACTTCTAGTATGGGCGATATCAGCGGCAATTGGCTCGCCCATCGTGCTCGGACTCAAC
AACACACCAGATCGAGTACCCGATTTGTGCTTATTTTATAACAGTGATTTTATAGTGTAC
TCATCGTTAAGTAGTTTTTATATACCTTGCATCATAATGGTATTTTTGTACTGGAATATT
TTTAAGGCACTTCGCACGAGAGCAAAAAAGCAGCGAGCGGCGAGGAAACACAATATATCA
GATTTAACAGCTGGTGGTAGTATAATTGAAAATATAGCACAAACAAAGAGATTAGCAGAG
ACGACGATGGATGGTAGTAGCAAAAGCTCGAAAATTATTCCTGAAGAAGAGCGTCCCACG
AATACTGGATCGGGATCAAATGATGAAGATGAAGAAAATGCGGGGTCACCCGAAGCAGAC
GCTGACGACTGTCATGTTATAGTTAACGATAAATCAACCGAATTTATGCTAGCCACAGTG
GTAGAAGAGACGAGCAAAAATACGCTAGCACAAATAACGACCAATCAAACGGATCCAAAT
GGCAATCAAGACTCGGGCTATGCACCGTCCAATGTTGAAGATTTGCTCGCTGTAAATCCA
TCATCGCCACCTGGTAGTCCTCATCATCATCAGGCCACTATTTTTGTTAACCGTAGTGTT
CATTATAATAAAGCTACAAAAAATGGCTCGACATCTTCAAATAACAATAACAAGCATCAA
ATACCAAATGCATCACCGAAAAAGGAGCCAACATTTAGTGTCGCACTGAAGCAATTATCA
ATGGTACGTTCAGGCGTACAGCAAGCACTTTCATTATCACGCAATGATTCCACAATGTCA
GCAAATTCACGCGAAAGCTCACGAAAAGATAATAAAAATACGCAAGCATCGAGGTTCACA
ATTTACAAAGTAAATAAGGCATCAAAGAAGAAAAGAGAAAAATCGTCAGCGAAAAAGGAG
CGGAAAGCAACAAAAACTCTCGCTATTGTGTTAGGTGTCTTCCTGATATGCTGGGTGCCC
TTCTTCACATGTAACATTATGGATGCCATGTGTACAAAGCTTAACTACGATTGTCAGCCT
GGCGTGACTGCATTTATTCTAACAACATGGCTTGGGTATATGAACAGTTTTTGGCTTCAA
ATTGGAAAATCGATTAACAATAATCCATCATCGAGTCTCGATTTACTAAAGGAAACACTT
TTGGAAGTAAAGGATTATAACGACGAGAGTGAAAATATTCTGATTCTTGGCGATTTTAAT
CACGAATTGAAATTGGGCAGTCCACTAGAGTTGTTCATGCTTCAATCTTTTGGCACAAGA
CTGTTCTCACCACGCGAACTGACAACAAACGCTCGAACAGTTATCGATGGAGTGTTTGGA
CGAATCGAAGATTATAATATCGAAGTTTTTATCTATGAATCGTATGCATCTCATCACAAA
CCATTAGTCATCCGAGTACATGAATTATAA
>g11032.t1 Gene=g11032 Length=809
MAINNTNNSLNSSAFHYYKLYNENATNLSTPVVTTSSSSFTRVTANLSPPLTPSTPVTTT
TLPQLAAATTIHTITSTITNNSLYSQNYYSNYTNDNNNSSSSSSSSSISNYTSSTLNSFN
QSTLYQYRNLSSNNSDENSYNDSAKISYESGSNFMLLLEDFGEYFYNYNGSDYNSSISIY
QTNCSLTNSTSCGDVTAPNSNYWALILVIFPFLTLFGNVLVILSVLRERTLQTVTNYFIV
SLAIADLLVAVVVMPFGVYYLVNGAWSLPNVVCDFYIAMDVICSTSSIFNLVAISIDRYI
AVTQPIKYAKHKNSRRVCLTILLVWAISAAIGSPIVLGLNNTPDRVPDLCLFYNSDFIVY
SSLSSFYIPCIIMVFLYWNIFKALRTRAKKQRAARKHNISDLTAGGSIIENIAQTKRLAE
TTMDGSSKSSKIIPEEERPTNTGSGSNDEDEENAGSPEADADDCHVIVNDKSTEFMLATV
VEETSKNTLAQITTNQTDPNGNQDSGYAPSNVEDLLAVNPSSPPGSPHHHQATIFVNRSV
HYNKATKNGSTSSNNNNKHQIPNASPKKEPTFSVALKQLSMVRSGVQQALSLSRNDSTMS
ANSRESSRKDNKNTQASRFTIYKVNKASKKKREKSSAKKERKATKTLAIVLGVFLICWVP
FFTCNIMDAMCTKLNYDCQPGVTAFILTTWLGYMNSFWLQIGKSINNNPSSSLDLLKETL
LEVKDYNDESENILILGDFNHELKLGSPLELFMLQSFGTRLFSPRELTTNARTVIDGVFG
RIEDYNIEVFIYESYASHHKPLVIRVHEL
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 26 | g11032.t1 | CDD | cd15053 | 7tmA_D2-like_dopamine_R | 201 | 390 | 2.25482E-113 |
| 12 | g11032.t1 | Gene3D | G3DSA:1.20.1070.10 | - | 203 | 406 | 6.2E-62 |
| 11 | g11032.t1 | Gene3D | G3DSA:1.20.1070.10 | - | 571 | 698 | 3.2E-20 |
| 41 | g11032.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 419 | 463 | - |
| 38 | g11032.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 436 | 450 | - |
| 36 | g11032.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 547 | 567 | - |
| 37 | g11032.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 547 | 569 | - |
| 39 | g11032.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 587 | 615 | - |
| 40 | g11032.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 587 | 602 | - |
| 2 | g11032.t1 | PANTHER | PTHR24248 | ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR | 199 | 698 | 2.0E-130 |
| 3 | g11032.t1 | PANTHER | PTHR24248:SF125 | DOPAMINE D2-LIKE RECEPTOR | 199 | 698 | 2.0E-130 |
| 9 | g11032.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 202 | 226 | 8.5E-41 |
| 4 | g11032.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 235 | 256 | 8.5E-41 |
| 8 | g11032.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 280 | 302 | 8.5E-41 |
| 6 | g11032.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 316 | 337 | 8.5E-41 |
| 7 | g11032.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 358 | 381 | 8.5E-41 |
| 5 | g11032.t1 | PRINTS | PR00237 | Rhodopsin-like GPCR superfamily signature | 643 | 667 | 8.5E-41 |
| 1 | g11032.t1 | Pfam | PF00001 | 7 transmembrane receptor (rhodopsin family) | 217 | 697 | 1.3E-74 |
| 18 | g11032.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 201 | - |
| 24 | g11032.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 202 | 226 | - |
| 14 | g11032.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 227 | 237 | - |
| 20 | g11032.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 238 | 262 | - |
| 16 | g11032.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 263 | 273 | - |
| 23 | g11032.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 274 | 296 | - |
| 15 | g11032.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 297 | 316 | - |
| 22 | g11032.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 317 | 337 | - |
| 17 | g11032.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 338 | 356 | - |
| 25 | g11032.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 357 | 380 | - |
| 13 | g11032.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 381 | 645 | - |
| 21 | g11032.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 646 | 663 | - |
| 19 | g11032.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 664 | 809 | - |
| 35 | g11032.t1 | ProSitePatterns | PS00237 | G-protein coupled receptors family 1 signature. | 286 | 302 | - |
| 42 | g11032.t1 | ProSiteProfiles | PS50262 | G-protein coupled receptors family 1 profile. | 217 | 703 | 40.873 |
| 34 | g11032.t1 | SMART | SM01381 | 7TM_GPCR_Srsx_2 | 211 | 698 | 4.4E-5 |
| 10 | g11032.t1 | SUPERFAMILY | SSF81321 | Family A G protein-coupled receptor-like | 182 | 697 | 5.58E-66 |
| 33 | g11032.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 203 | 225 | - |
| 32 | g11032.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 237 | 259 | - |
| 29 | g11032.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 274 | 296 | - |
| 31 | g11032.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 317 | 339 | - |
| 27 | g11032.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 359 | 381 | - |
| 28 | g11032.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 648 | 670 | - |
| 30 | g11032.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 680 | 699 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0007186 | G protein-coupled receptor signaling pathway | BP |
| GO:0016021 | integral component of membrane | CC |
| GO:0004930 | G protein-coupled receptor activity | MF |
KEGG
Orthology
- This transcript has been annotated with K04145 (dopamine receptor D2)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
