General information for g11039.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Cytochrome P450 4g15.
Parent gene
- The parent gene g11039 is located on chr_1: 13633583..13640216 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11039 | g11039.t1 | TTS | g11039.t1 | 13632039 | 13632039 |
| chr_1 | g11039 | g11039.t1 | isoform | g11039.t1 | 13632355 | 13640216 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon1 | 13632355 | 13632515 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS1 | 13632355 | 13632515 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon2 | 13632582 | 13632764 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS2 | 13632582 | 13632764 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon3 | 13632836 | 13632874 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS3 | 13632836 | 13632874 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon4 | 13632927 | 13633091 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS4 | 13632927 | 13633091 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon5 | 13633238 | 13633586 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS5 | 13633238 | 13633586 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon6 | 13633665 | 13633791 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS6 | 13633665 | 13633791 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon7 | 13634550 | 13634616 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS7 | 13634550 | 13634616 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon8 | 13634837 | 13635025 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS8 | 13634837 | 13635025 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon9 | 13635227 | 13635530 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS9 | 13635227 | 13635530 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon10 | 13638793 | 13638929 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS10 | 13638793 | 13638929 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon11 | 13638996 | 13639178 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS11 | 13638996 | 13639178 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon12 | 13639246 | 13639281 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS12 | 13639246 | 13639281 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon13 | 13639373 | 13639537 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS13 | 13639373 | 13639537 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon14 | 13639822 | 13640086 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS14 | 13639822 | 13640086 |
| chr_1 | g11039 | g11039.t1 | exon | g11039.t1.exon15 | 13640154 | 13640216 |
| chr_1 | g11039 | g11039.t1 | cds | g11039.t1.CDS15 | 13640154 | 13640216 |
| chr_1 | g11039 | g11039.t1 | TSS | g11039.t1 | NA | NA |
Sequences
>g11039.t1 Gene=g11039 Length=2433
ATGACAAATTATTATCGTGACGAGATGCAAGTTCGTTCAGTTTGTTATTCTTCAGCTGAT
CGTCTTATTACAGCAAAGCGTGAAGCTTTAGCACCTGATTTTGACTACAATGCAAATAGT
AATTTCATAGAACAGCATGTTAAACACAATTATATCAACAGAAATGAACCAACATTGCCA
AAAGATGAAGATATTCCGGCTAGAAAGATTTTTATCGATCATGTCATTTGTAATGACACA
AAATTTACTGATTCGGAAATTCGTGATCATGTTTATACAGTTGTCGCCGCAGGAAGTGAA
ACAACAGCTCTTCAAACTGCACACACCATTATGTTACTTGCAACTCATCAAGAAATTCAG
GATCGTGTTGCTACTGAAATTAAAGAAGTTTTCTACTCAGAAGACGTTGAAATTAGTTAC
GACAACATTGTAAAGCTTGAATATCTTGAAAGAGTCATAAAAGAGTCGCTTCGTTTGTGT
CCAGTTGTGCCAATAATTGGAAGAGAAACACAAGCAACATTAAAACTTGACGATTATGAA
ATACCTGCAGGAATAACATTGTTAATAAATTTCTACACACTTCATCGAAGACCAGACATT
TGGGGAGATGATGCTGAAGAATTTAATCCTGATCATTTCTTGCCTGAATTTGTTGAAAAA
CGACATCCTTATAGTTTTCTGCCTTTCAATGGTGGACAAAGAAATTGTATTGGTTACCGT
TATGCAATGATAGCACTAAAAATTATTCTCGTTCATTTATTACGACGCTACAAATTCAAC
ACATCAATGACATACAAAGATCTTCGATTCCGCACCGACATCAACCTCAAATTGTGCACA
GAACATTTATGGCATTTTGAGCATAAAAAGTTTTATAAATTTGCTGATAAAATTCCAAGT
GCTAAAAATTATGGAATTTTGGGACATGGTCCACATTTCTTGGGTAAAAATGATGAGGGT
CGTTTTAAATTGCTACATGAACTGTGTTTAAAATTTGATCATTTGATAAAACTATGGCTC
GGGCCAGCAATTTTATGGGTGCTTGTGAATGATCCAAAGACTATTCAAAAAGTGCTACTG
TCACCTGTGTGTCTTGAAAAGCCTTTTTTCTATAAATTTCTTCGTTTAGATTCTGGATTA
ATTTCTGCTAGATATGATGTCTGGAAAATTCATCGAAAATCACTCAATTATTCTTTCAAC
CTCAAAATTCTTCAAACCTTTATTCCAATTTTTATCGAAAATTCACAAAAACTTGTCAAC
GATTTGGCTGTGAATATTGGAAAACGCAAGGAATTTGATATGCTAGCATACACATCAAAA
TCTGCTCTCAATATGATCTGCGGAACTTCATTTGGATTGGATATAAAAAATATTGCACTT
AGTGATGATGTTTTTCATGCTCTTGAAAAATTAAATCGAGCCATCTCAGCCCGAAGTCAA
TCATTCTTTCTTTATTCGGAGCCAATTTATCGCATGTCACGATATTATCGCGATGAAATG
GAATCGCGGTCAGTTTGCTATTCATCAGCTGATATGATTATAAAAGTAAAAAGAAAAGCG
CTAGAGGATGAAGAAAGTGTTAACAATAATCAGATTGATCGAGAAAATTATGAAGATGAA
TTATATCGTGAAACAATTGAAAGATTTCCAGAATTAAGAGCACTTAAAAAAGAAGACATA
ATTAATCAAATCAAAGCAACATTCAATAAAAATAAGAAAAAGTCAACAATCACAGAAGAG
GATGAAAATATGCCAACAAGAAAAATTTTTATTGATCACGTAATATGTAATGACACAAAG
TTCAACGATTCCGAAGTGCGTGATCATGTTTACACGGTTGTTGCTGCTGGCAGTGAAACA
ACAGCTCTTCAAACTGCACACACGATTATGTTACTTGCAACTCATCAAGAAATTCAGAAT
CGTGTTGCTGCTGAAATCAAAGAAGTTTTCTATTCAGATGACATTGAAATCAGTTACGAC
AACATTGTAAAGCTTGAATATCTTGAAAGAGTCATAAAAGAGTCGCTTCGTTTATGTCCA
GTTGTGCCAGTAATTGGAAGAGAAACACAAGCGCCAATAAAGCTAGACGATGACATAGAA
ATACCAGCAGGAATAACATTGTTAATAAATTTCTACACACTTCATCGAAGACCAGACATT
TGGGGTGATGATGCTGAAGAATTTAATCCTGATCATTTCTTGCCTGAATTTGTTGAAAAA
CGACATCCTTATAGTTTTCTGCCTTTCAGTGGTGGACAAAGAAATTGTATTGGCTACCGT
TATGCAATGATAGCACTAAAAATTATTCTCGTTCATCTATTACGACGCTACAAATTCAAC
ACATCAATGACATACAAAGATCTTCGATTCCGAACCGATATCAACCTCAAATTGTGCACA
AAACATTTAGTCAGTATCGAATTAAGAGATTAG
>g11039.t1 Gene=g11039 Length=810
MTNYYRDEMQVRSVCYSSADRLITAKREALAPDFDYNANSNFIEQHVKHNYINRNEPTLP
KDEDIPARKIFIDHVICNDTKFTDSEIRDHVYTVVAAGSETTALQTAHTIMLLATHQEIQ
DRVATEIKEVFYSEDVEISYDNIVKLEYLERVIKESLRLCPVVPIIGRETQATLKLDDYE
IPAGITLLINFYTLHRRPDIWGDDAEEFNPDHFLPEFVEKRHPYSFLPFNGGQRNCIGYR
YAMIALKIILVHLLRRYKFNTSMTYKDLRFRTDINLKLCTEHLWHFEHKKFYKFADKIPS
AKNYGILGHGPHFLGKNDEGRFKLLHELCLKFDHLIKLWLGPAILWVLVNDPKTIQKVLL
SPVCLEKPFFYKFLRLDSGLISARYDVWKIHRKSLNYSFNLKILQTFIPIFIENSQKLVN
DLAVNIGKRKEFDMLAYTSKSALNMICGTSFGLDIKNIALSDDVFHALEKLNRAISARSQ
SFFLYSEPIYRMSRYYRDEMESRSVCYSSADMIIKVKRKALEDEESVNNNQIDRENYEDE
LYRETIERFPELRALKKEDIINQIKATFNKNKKKSTITEEDENMPTRKIFIDHVICNDTK
FNDSEVRDHVYTVVAAGSETTALQTAHTIMLLATHQEIQNRVAAEIKEVFYSDDIEISYD
NIVKLEYLERVIKESLRLCPVVPVIGRETQAPIKLDDDIEIPAGITLLINFYTLHRRPDI
WGDDAEEFNPDHFLPEFVEKRHPYSFLPFSGGQRNCIGYRYAMIALKIILVHLLRRYKFN
TSMTYKDLRFRTDINLKLCTKHLVSIELRD
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 22 | g11039.t1 | Gene3D | G3DSA:1.10.630.10 | Cytochrome p450 | 28 | 278 | 5.8E-70 |
| 23 | g11039.t1 | Gene3D | G3DSA:1.10.630.10 | Cytochrome p450 | 317 | 536 | 1.8E-21 |
| 21 | g11039.t1 | Gene3D | G3DSA:1.10.630.10 | Cytochrome p450 | 537 | 802 | 1.7E-67 |
| 4 | g11039.t1 | PANTHER | PTHR24291:SF106 | CYTOCHROME P450 4G1-RELATED | 75 | 278 | 3.4E-149 |
| 6 | g11039.t1 | PANTHER | PTHR24291 | CYTOCHROME P450 FAMILY 4 | 75 | 278 | 3.4E-149 |
| 3 | g11039.t1 | PANTHER | PTHR24291:SF106 | CYTOCHROME P450 4G1-RELATED | 283 | 803 | 3.4E-149 |
| 5 | g11039.t1 | PANTHER | PTHR24291 | CYTOCHROME P450 FAMILY 4 | 283 | 803 | 3.4E-149 |
| 11 | g11039.t1 | PRINTS | PR00463 | E-class P450 group I signature | 86 | 103 | 3.3E-14 |
| 13 | g11039.t1 | PRINTS | PR00385 | P450 superfamily signature | 97 | 114 | 1.1E-8 |
| 10 | g11039.t1 | PRINTS | PR00463 | E-class P450 group I signature | 106 | 132 | 3.3E-14 |
| 9 | g11039.t1 | PRINTS | PR00463 | E-class P450 group I signature | 669 | 687 | 3.3E-14 |
| 15 | g11039.t1 | PRINTS | PR00385 | P450 superfamily signature | 670 | 681 | 1.1E-8 |
| 12 | g11039.t1 | PRINTS | PR00463 | E-class P450 group I signature | 711 | 735 | 3.3E-14 |
| 8 | g11039.t1 | PRINTS | PR00463 | E-class P450 group I signature | 746 | 756 | 3.3E-14 |
| 14 | g11039.t1 | PRINTS | PR00385 | P450 superfamily signature | 747 | 756 | 1.1E-8 |
| 7 | g11039.t1 | PRINTS | PR00463 | E-class P450 group I signature | 756 | 779 | 3.3E-14 |
| 16 | g11039.t1 | PRINTS | PR00385 | P450 superfamily signature | 756 | 767 | 1.1E-8 |
| 2 | g11039.t1 | Pfam | PF00067 | Cytochrome P450 | 43 | 262 | 1.1E-59 |
| 1 | g11039.t1 | Pfam | PF00067 | Cytochrome P450 | 306 | 782 | 3.5E-76 |
| 25 | g11039.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 756 | - |
| 26 | g11039.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 757 | 774 | - |
| 24 | g11039.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 775 | 810 | - |
| 20 | g11039.t1 | ProSitePatterns | PS00086 | Cytochrome P450 cysteine heme-iron ligand signature. | 229 | 238 | - |
| 19 | g11039.t1 | ProSitePatterns | PS00086 | Cytochrome P450 cysteine heme-iron ligand signature. | 749 | 758 | - |
| 17 | g11039.t1 | SUPERFAMILY | SSF48264 | Cytochrome P450 | 49 | 277 | 1.44E-66 |
| 18 | g11039.t1 | SUPERFAMILY | SSF48264 | Cytochrome P450 | 298 | 809 | 2.62E-88 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0020037 | heme binding | MF |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | MF |
| GO:0005506 | iron ion binding | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
- This transcript has been annotated with K15007 (cytochrome P450 family 313 [EC:1.14.-.-])
Pathway
This gene does not belong to any pathways.
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
