General information for g11061.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as U1 small nuclear ribonucleoprotein 70 kDa.
Parent gene
- The parent gene g11061 is located on chr_1: 13739132..13741509 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11061 | g11061.t1 | TSS | g11061.t1 | 13736261 | 13736261 |
| chr_1 | g11061 | g11061.t1 | isoform | g11061.t1 | 13736448 | 13739132 |
| chr_1 | g11061 | g11061.t1 | exon | g11061.t1.exon1 | 13736448 | 13736591 |
| chr_1 | g11061 | g11061.t1 | cds | g11061.t1.CDS1 | 13736448 | 13736591 |
| chr_1 | g11061 | g11061.t1 | exon | g11061.t1.exon2 | 13736654 | 13736836 |
| chr_1 | g11061 | g11061.t1 | cds | g11061.t1.CDS2 | 13736654 | 13736836 |
| chr_1 | g11061 | g11061.t1 | exon | g11061.t1.exon3 | 13736900 | 13737044 |
| chr_1 | g11061 | g11061.t1 | cds | g11061.t1.CDS3 | 13736900 | 13737044 |
| chr_1 | g11061 | g11061.t1 | exon | g11061.t1.exon4 | 13738147 | 13738386 |
| chr_1 | g11061 | g11061.t1 | cds | g11061.t1.CDS4 | 13738147 | 13738386 |
| chr_1 | g11061 | g11061.t1 | exon | g11061.t1.exon5 | 13738446 | 13738611 |
| chr_1 | g11061 | g11061.t1 | cds | g11061.t1.CDS5 | 13738446 | 13738611 |
| chr_1 | g11061 | g11061.t1 | exon | g11061.t1.exon6 | 13738673 | 13738797 |
| chr_1 | g11061 | g11061.t1 | cds | g11061.t1.CDS6 | 13738673 | 13738797 |
| chr_1 | g11061 | g11061.t1 | exon | g11061.t1.exon7 | 13739002 | 13739132 |
| chr_1 | g11061 | g11061.t1 | cds | g11061.t1.CDS7 | 13739002 | 13739132 |
| chr_1 | g11061 | g11061.t1 | TTS | g11061.t1 | 13739293 | 13739293 |
Sequences
>g11061.t1 Gene=g11061 Length=1134
ATGACTCAATATCTGCCAGCCAATTTATTGGCTTTATTCGCTGCTCGCGATCCTATTCCA
TTTTTGCCACCTCCTGATAAACTTCCACATGAGAAAAAGACGCGAGGATATTTAGGAGTT
GGTTCATTTTTAGATCAATTTGAGGATCCTAAAGATACACCACCACCCACAAGAGTCGAA
ACAAAAGAAGAACGAATGGAAAGACGTCGAAGAGAAAAAGCTGAGCAAGTAGCTTACAAG
CTTGAACGAGAAATAGCACTTTGGGATCCAACATCGATCGAAAATACAACAGAAGATCCT
TTCAAAACACTTTTTGTTGCTCGTATAAATTATGACACATCAGAATCGAAATTAAGAAGA
GAATTTGAAGTGTATGGACCAATAAGGAAAATTATAATGATCCACGATCAAGATTCAGGC
AAACCTCGTGGTTATGCGTTTATTGAGTACGAACATGAAAGAGACATGCATTCTGCATAC
AAACATGCTGATGGTAAAAAAATTGATGGTAGAAGGGTATTGGTTGACGTTGAACGTGCA
AGAACAGTTAAAGGATGGTTACCTCGAAGACTTGGAGGTGGTTTAGGTGGAACAAGACGT
GGTGGTGCTGAGGTAAATATTAAGCACAGTGGACGAGAAGATAATGTACGTGAAAAGGAG
AGATATCGTCTTGAAAGAGAAAGAGAAGATAATCGTCGTCTTGATGATAGAAGATTTGAT
AGAAGACGATCTCGATCACATGAAAAAAGTCGTGAAAGAAGACGATCTCGATCGAAAGAA
CGTAGAAGACATAGGTCGCGTGAAGAAGATTATGAAAGACATGATAGAAGAGAAAAATCG
CGTGAGAAGAAACGCCGAAGAACACGTTCTAGAGATCGAGATCGTTCTGAACGTAAACGC
GATAAACGTGATCGTTCTAGATCACGTGAAAGACGCCGTGATAAGGACAAGAAAGAGCGT
AAACCAGAGTTCGATATTAAAATTAAGGAAGAACCCATTGATGATTATCCGGACTACACG
CAACATGATTATGGTCAATATGCCAATCAAGTTAAGTATGAATCAGGTGATGAAGAAAAA
TATAGACCAAATGAGCAAGATGGAGCCGCTTATGGTTATCGACAAGATTATTAA
>g11061.t1 Gene=g11061 Length=377
MTQYLPANLLALFAARDPIPFLPPPDKLPHEKKTRGYLGVGSFLDQFEDPKDTPPPTRVE
TKEERMERRRREKAEQVAYKLEREIALWDPTSIENTTEDPFKTLFVARINYDTSESKLRR
EFEVYGPIRKIIMIHDQDSGKPRGYAFIEYEHERDMHSAYKHADGKKIDGRRVLVDVERA
RTVKGWLPRRLGGGLGGTRRGGAEVNIKHSGREDNVREKERYRLEREREDNRRLDDRRFD
RRRSRSHEKSRERRRSRSKERRRHRSREEDYERHDRREKSREKKRRRTRSRDRDRSERKR
DKRDRSRSRERRRDKDKKERKPEFDIKIKEEPIDDYPDYTQHDYGQYANQVKYESGDEEK
YRPNEQDGAAYGYRQDY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g11061.t1 | CDD | cd12236 | RRM_snRNP70 | 101 | 188 | 3.43458E-57 |
| 7 | g11061.t1 | Coils | Coil | Coil | 217 | 237 | - |
| 6 | g11061.t1 | Gene3D | G3DSA:3.30.70.330 | - | 89 | 214 | 3.1E-36 |
| 18 | g11061.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 47 | 71 | - |
| 10 | g11061.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 51 | 71 | - |
| 12 | g11061.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 197 | 218 | - |
| 15 | g11061.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 240 | 339 | - |
| 17 | g11061.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 247 | 262 | - |
| 13 | g11061.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 263 | 278 | - |
| 11 | g11061.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 279 | 293 | - |
| 16 | g11061.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 294 | 338 | - |
| 14 | g11061.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 353 | 377 | - |
| 3 | g11061.t1 | PANTHER | PTHR13952 | U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KD | 1 | 314 | 3.9E-98 |
| 4 | g11061.t1 | PANTHER | PTHR13952:SF5 | U1 SMALL NUCLEAR RIBONUCLEOPROTEIN 70 KDA | 1 | 314 | 3.9E-98 |
| 1 | g11061.t1 | Pfam | PF12220 | U1 small nuclear ribonucleoprotein of 70kDa MW N terminal | 4 | 91 | 1.8E-24 |
| 2 | g11061.t1 | Pfam | PF00076 | RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) | 104 | 173 | 3.2E-17 |
| 19 | g11061.t1 | ProSiteProfiles | PS50102 | Eukaryotic RNA Recognition Motif (RRM) profile. | 102 | 180 | 17.933 |
| 9 | g11061.t1 | SMART | SM00360 | rrm1_1 | 103 | 176 | 3.5E-23 |
| 5 | g11061.t1 | SUPERFAMILY | SSF54928 | RNA-binding domain, RBD | 85 | 202 | 1.09E-28 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0030619 | U1 snRNA binding | MF |
| GO:0003676 | nucleic acid binding | MF |
KEGG
Orthology
- This transcript has been annotated with K11093 (U1 small nuclear ribonucleoprotein 70kDa)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
