General information for g11158.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Deoxynucleoside kinase.
Parent gene
- The parent gene g11158 is located on chr_1: 14368586..14369294 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11158 | g11158.t1 | TTS | g11158.t1 | 14368486 | 14368486 |
| chr_1 | g11158 | g11158.t1 | isoform | g11158.t1 | 14368586 | 14369294 |
| chr_1 | g11158 | g11158.t1 | exon | g11158.t1.exon1 | 14368586 | 14369098 |
| chr_1 | g11158 | g11158.t1 | cds | g11158.t1.CDS1 | 14368586 | 14369098 |
| chr_1 | g11158 | g11158.t1 | exon | g11158.t1.exon2 | 14369160 | 14369294 |
| chr_1 | g11158 | g11158.t1 | cds | g11158.t1.CDS2 | 14369160 | 14369294 |
| chr_1 | g11158 | g11158.t1 | TSS | g11158.t1 | 14369357 | 14369357 |
Sequences
>g11158.t1 Gene=g11158 Length=648
ATGTCAAGTTTGAAGAAGACAGTATTTATAGAAGGTAATACTGCGTCCGGCAAGTCAACA
TTGCTTAAATACTTTCAAAAATTTGATGAAATTCTCGTTTTACAAGAAGATATCGAAAAA
TGGACAAATTTTCATGGTTACAACTTGTTGGAACTAAAATATAAAAATCCAGATTTCTTT
CAGTTTCCATTTCAAAGTTATGCCACTTTAACTCGATTGAGACAACATCTTCAAAATTCG
AATAAAGCAATAAAAATGATGGAAAGATCTCTTTTCTCTGCAAGGCATATTTTTGTTGAA
GCTCAAAAAAATTTGAATCTTATGCATGAAGGAAATTATCATGTGTTGCAAGAATGGTAC
GATTATATCGATGAATATCATAAAATTCAAACTGATCTCTTTATTTACATTCAAACTGAT
CCGTACGTTGCATTTAAACGAATACAAGAACGTGCAAGGAAGGAAGAAAAGGATATTACG
TTTGAGTATTTAAAGAAAATACATCAGCTTCATGAAGAGCTATTTATTGAGAGAGCCAAT
ATATTACCTGGAAAAGTGTTGGTAATTGATGGAAATTTGAATCAAACAGAGATGATGGAA
GAATTCAAGAAATGTGAATATGAAATATTCAGTTTTATTGAATCTTAA
>g11158.t1 Gene=g11158 Length=215
MSSLKKTVFIEGNTASGKSTLLKYFQKFDEILVLQEDIEKWTNFHGYNLLELKYKNPDFF
QFPFQSYATLTRLRQHLQNSNKAIKMMERSLFSARHIFVEAQKNLNLMHEGNYHVLQEWY
DYIDEYHKIQTDLFIYIQTDPYVAFKRIQERARKEEKDITFEYLKKIHQLHEELFIERAN
ILPGKVLVIDGNLNQTEMMEEFKKCEYEIFSFIES
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g11158.t1 | CDD | cd01673 | dNK | 10 | 192 | 3.87115E-42 |
| 6 | g11158.t1 | Coils | Coil | Coil | 70 | 90 | - |
| 5 | g11158.t1 | Gene3D | G3DSA:3.40.50.300 | - | 2 | 194 | 8.4E-57 |
| 2 | g11158.t1 | PANTHER | PTHR10513:SF24 | THYMIDINE KINASE 2, MITOCHONDRIAL | 5 | 204 | 2.8E-57 |
| 3 | g11158.t1 | PANTHER | PTHR10513 | DEOXYNUCLEOSIDE KINASE | 5 | 204 | 2.8E-57 |
| 7 | g11158.t1 | PIRSF | PIRSF000705 | DNK | 1 | 215 | 1.1E-53 |
| 1 | g11158.t1 | Pfam | PF01712 | Deoxynucleoside kinase | 9 | 201 | 7.0E-43 |
| 4 | g11158.t1 | SUPERFAMILY | SSF52540 | P-loop containing nucleoside triphosphate hydrolases | 6 | 209 | 1.72E-35 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0019136 | deoxynucleoside kinase activity | MF |
| GO:0005524 | ATP binding | MF |
| GO:0006139 | nucleobase-containing compound metabolic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
