Gene loci information

Transcript annotation

  • This transcript has been annotated as Adenosylhomocysteinase-like 1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g11186 g11186.t9 TTS g11186.t9 14472828 14472828
chr_1 g11186 g11186.t9 isoform g11186.t9 14473853 14475396
chr_1 g11186 g11186.t9 exon g11186.t9.exon1 14473853 14474127
chr_1 g11186 g11186.t9 cds g11186.t9.CDS1 14473853 14474127
chr_1 g11186 g11186.t9 exon g11186.t9.exon2 14474224 14474626
chr_1 g11186 g11186.t9 cds g11186.t9.CDS2 14474224 14474626
chr_1 g11186 g11186.t9 exon g11186.t9.exon3 14474893 14475029
chr_1 g11186 g11186.t9 cds g11186.t9.CDS3 14474893 14475029
chr_1 g11186 g11186.t9 exon g11186.t9.exon4 14475098 14475244
chr_1 g11186 g11186.t9 cds g11186.t9.CDS4 14475098 14475244
chr_1 g11186 g11186.t9 exon g11186.t9.exon5 14475344 14475396
chr_1 g11186 g11186.t9 cds g11186.t9.CDS5 14475344 14475374
chr_1 g11186 g11186.t9 TSS g11186.t9 14475396 14475396

Sequences

>g11186.t9 Gene=g11186 Length=1015
AGTTGGCTCTGAGAAACTGACGATGAAACATCGCAGACGCAGCAGTGCTTTTTCATCATA
TACAGGAAGTTCAAGCGAGGACGATGATGCATCACCTCGTGAAAAAATTCAAAGCAATTC
GAAAGGATTTGCGGACTTTTGTGTAAGAAATATTCAACAACATGCGTTTGGCCGGCGTGA
AATTGAAATTGCCGAGCAAGAGATGCCAGGAATTATGGCATTAAGGAAACGTGCTTCCGA
AGATAAGCCCCTTAAGAATGCTAAAATTGTTGGATGCACACATGTTAATGCGCAAACGGC
TGTTCTTATTGAAACTTTAGCAGCACTCGGAGCTTCTGTTCGTTGGGCAGCCTGCAACAT
TTATTCAACACAAAATGAAGTGGCCGCAGCTCTAGCCGAAAGTGGATTTAGTGTATTTGC
GTGGCGCGGCGAGACGGAAGAAGATTTCTGGTGGTGTATTGATAAATGTGTTAATGCAGA
AAATTGGCAACCAAACCTGATACTCGATGATGGTGGTGATGCAACGCATTTAATGTTGAA
AAAATATCCAGCCATGTTTAAAATGGTGAAGGGTATCGTTGAAGAGAGTGTCACAGGCGT
ACATCGACTTTATCAATTGTCTAAAAGTGGCAAACTGACAGTTCCTGCGATGAATGTCCA
TGATTCTGTTATCAAGACTAAATTTGATAATTTCTATAGTTGCAAAGAGAGCATAATTGA
TAGTTTAAAACGTTCGACTGACATTATGTTTTCGGGAAAACAAGTCGCACTATGTGGATA
TGGTGAAGTCGGTAAAGGTTGTTCGCAAGCTTTAAAAGCACTCGGATGCATCGTCTACGT
CACCGAAATCGATCCTATTTGTGCGCTACAAGCAAGCGTTGATGGCTTTCGTGTTGTTAA
GCTAAATGAGATAATTCGAAATGTTGATATCGTAATCACGACTACTGGCAATAAAAGCGT
AGTTACTCGAGAGCACATGGAGAAAATGAAGAATGGCTGCATTGTATGCAATATG

>g11186.t9 Gene=g11186 Length=331
MKHRRRSSAFSSYTGSSSEDDDASPREKIQSNSKGFADFCVRNIQQHAFGRREIEIAEQE
MPGIMALRKRASEDKPLKNAKIVGCTHVNAQTAVLIETLAALGASVRWAACNIYSTQNEV
AAALAESGFSVFAWRGETEEDFWWCIDKCVNAENWQPNLILDDGGDATHLMLKKYPAMFK
MVKGIVEESVTGVHRLYQLSKSGKLTVPAMNVHDSVIKTKFDNFYSCKESIIDSLKRSTD
IMFSGKQVALCGYGEVGKGCSQALKALGCIVYVTEIDPICALQASVDGFRVVKLNEIIRN
VDIVITTTGNKSVVTREHMEKMKNGCIVCNM

Protein features from InterProScan

Transcript Database ID Name Start End E.value
10 g11186.t9 CDD cd00401 SAHH 48 331 0.0
9 g11186.t9 Gene3D G3DSA:3.40.50.1480 - 21 173 1.3E-67
8 g11186.t9 Gene3D G3DSA:3.40.50.1480 - 174 229 8.3E-19
7 g11186.t9 Gene3D G3DSA:3.40.50.720 - 230 331 1.9E-46
15 g11186.t9 MobiDBLite mobidb-lite consensus disorder prediction 1 28 -
3 g11186.t9 PANTHER PTHR23420 ADENOSYLHOMOCYSTEINASE 24 331 2.0E-183
4 g11186.t9 PANTHER PTHR23420:SF2 ADENOSYLHOMOCYSTEINASE 3 24 331 2.0E-183
1 g11186.t9 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 38 173 3.1E-65
2 g11186.t9 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 223 331 3.1E-52
12 g11186.t9 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 110 124 -
11 g11186.t9 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 245 261 -
14 g11186.t9 SMART SM00996 AdoHcyase_2 38 331 3.5E-121
13 g11186.t9 SMART SM00997 AdoHcyase_NAD_2 223 331 2.1E-46
6 g11186.t9 SUPERFAMILY SSF52283 Formate/glycerate dehydrogenase catalytic domain-like 38 226 5.87E-79
5 g11186.t9 SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains 223 331 7.64E-43

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0004013 adenosylhomocysteinase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values