General information for g11190.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Serine/threonine-protein kinase PAK 3.
Parent gene
- The parent gene g11190 is located on chr_1: 14497518..14504469 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11190 | g11190.t3 | TTS | g11190.t3 | 14491201 | 14491201 |
| chr_1 | g11190 | g11190.t3 | isoform | g11190.t3 | 14491774 | 14493383 |
| chr_1 | g11190 | g11190.t3 | exon | g11190.t3.exon1 | 14491774 | 14492275 |
| chr_1 | g11190 | g11190.t3 | cds | g11190.t3.CDS1 | 14492192 | 14492275 |
| chr_1 | g11190 | g11190.t3 | exon | g11190.t3.exon2 | 14492879 | 14493063 |
| chr_1 | g11190 | g11190.t3 | cds | g11190.t3.CDS2 | 14492879 | 14493063 |
| chr_1 | g11190 | g11190.t3 | exon | g11190.t3.exon3 | 14493125 | 14493198 |
| chr_1 | g11190 | g11190.t3 | cds | g11190.t3.CDS3 | 14493125 | 14493198 |
| chr_1 | g11190 | g11190.t3 | exon | g11190.t3.exon4 | 14493261 | 14493383 |
| chr_1 | g11190 | g11190.t3 | cds | g11190.t3.CDS4 | 14493261 | 14493358 |
| chr_1 | g11190 | g11190.t3 | TSS | g11190.t3 | NA | NA |
Sequences
>g11190.t3 Gene=g11190 Length=884
CAAAAGTGACAATATTTTACTTGGTATGGATGGTAGCGTTAAGCTAACTGATTTTGGTTT
TTGCGCACAAATTTCACCTGAGCAATCAAAAAGGACTACAATGGTCGGTACACCATATTG
GATGGCACCGGAAGTTGTGACAAGGAAACAGTATGGACCAAAAGTTGACTTATGGAGTCT
TGGAATTATGGCAATTGAAATGATTGAAGGGGAGCCACCGTATCTGAATGAAAATCCGCT
TAGAGCGCTTTATTTGATTGCGACACATGGTAAACCAGAAATCAAAGATAAGGATAAATT
GAGTCCAGTTTTTCAAGATTTTCTCGATAAATGCCTTGAGGTTGATGTTGATCAACGATC
AAGCGCTATGGAATTACTAAAACATCCTTTCTTAAAACTCGCACGTCCATTGGCTAGTCT
AACTCCATTAATAATAGCAGCAAAAGAGGCAACAAAAGGGCACTAATGCAAAAAACATTA
TTAATAATTAAATTGAGTGAGTGAGTGAAGAGAAAAAATTAAGTTTTCTATCTCTATCTC
TCTCTTAAAATGAAAAGCTCTATTTAGACGACGATGAGATGAGAGATGAGTAAAAGAATT
CATATAATAAAATTGCTATATATCTTCCTTCTACTAGAATAATATGAAGAAAAACAAAAG
AAAATAGATTAATGAAATGAGTATGACGAGAAAAGTTAATTAAGTTGTGAAAGTCAAAAA
AAATTTCTATTCTTCAATATCTTTTTCAAATGAGTCGCTTTAAATTTGTTATAAACTCAC
CTTCTTCTTATTTGTGCTAAAAGCATCTTCTCTTATCATCTTATCCCATTCATAAATACA
AACACTCATAAACACCTTTTTTTGCATTTCATAATTACAAACAA
>g11190.t3 Gene=g11190 Length=146
MDGSVKLTDFGFCAQISPEQSKRTTMVGTPYWMAPEVVTRKQYGPKVDLWSLGIMAIEMI
EGEPPYLNENPLRALYLIATHGKPEIKDKDKLSPVFQDFLDKCLEVDVDQRSSAMELLKH
PFLKLARPLASLTPLIIAAKEATKGH
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g11190.t3 | Gene3D | G3DSA:1.10.510.10 | Transferase(Phosphotransferase) domain 1 | 1 | 146 | 0.000 |
| 2 | g11190.t3 | PANTHER | PTHR48015:SF35 | NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE | 1 | 145 | 0.000 |
| 3 | g11190.t3 | PANTHER | PTHR48015 | SERINE/THREONINE-PROTEIN KINASE TAO | 1 | 145 | 0.000 |
| 1 | g11190.t3 | Pfam | PF00069 | Protein kinase domain | 2 | 123 | 0.000 |
| 7 | g11190.t3 | ProSiteProfiles | PS50011 | Protein kinase domain profile. | 1 | 123 | 25.404 |
| 5 | g11190.t3 | SMART | SM00220 | serkin_6 | 1 | 123 | 0.000 |
| 4 | g11190.t3 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 2 | 125 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005524 | ATP binding | MF |
| GO:0004672 | protein kinase activity | MF |
| GO:0006468 | protein phosphorylation | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
