Gene loci information

Transcript annotation

  • This transcript has been annotated as Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g11211 g11211.t60 TTS g11211.t60 14598503 14598503
chr_1 g11211 g11211.t60 isoform g11211.t60 14598609 14601436
chr_1 g11211 g11211.t60 exon g11211.t60.exon1 14598609 14598730
chr_1 g11211 g11211.t60 exon g11211.t60.exon2 14598786 14599139
chr_1 g11211 g11211.t60 exon g11211.t60.exon3 14599200 14599314
chr_1 g11211 g11211.t60 cds g11211.t60.CDS1 14599304 14599314
chr_1 g11211 g11211.t60 exon g11211.t60.exon4 14599565 14599751
chr_1 g11211 g11211.t60 cds g11211.t60.CDS2 14599565 14599751
chr_1 g11211 g11211.t60 exon g11211.t60.exon5 14599808 14600000
chr_1 g11211 g11211.t60 cds g11211.t60.CDS3 14599808 14600000
chr_1 g11211 g11211.t60 exon g11211.t60.exon6 14600059 14600578
chr_1 g11211 g11211.t60 cds g11211.t60.CDS4 14600059 14600578
chr_1 g11211 g11211.t60 exon g11211.t60.exon7 14600645 14601436
chr_1 g11211 g11211.t60 cds g11211.t60.CDS5 14600645 14600984
chr_1 g11211 g11211.t60 TSS g11211.t60 14601549 14601549

Sequences

>g11211.t60 Gene=g11211 Length=2283
ATGTCAAAACGAAGAATAGAAGTACTGGACCCATTTATCAAGAAACGAAGGTAAAATATC
AAAAAAGTCAATTTTTATAATTTGTTTTCACAAAACGTTTTTTTTTGTTTTCTAGAGAAG
AAAAAGGAATTCCTGTTGATAGTGGCTCATCTTCATCATCAGTCGTAATTACAACAACAC
CAGTTATGTCTGGATCGATAAATCCACTCACAGGCGCACTTTATTCTGCAAATTATCATG
CTCTATATAAAAAGCGTGTTTTGTTGCCTGTATTTGAATATCGTGCTGATTTCATGCGAT
TACTAGCAGAACATCAATGCATTGTATTAGTCGGCGAAACTGGATCAGGTTAGTATTATT
TATATATGAATCAATATTGTTATCATGAATTTTCATATATTTAAGGAAAAACAACACAAA
TTCCACAATGGGCAGTAGATTACGCGCGAAGTATGAGTAGTAAAGGAGTTGCATGTACAC
AGCCAAGAAGAGTAGCAGCAATGTCAGTTGCTCAGCGTGTTTCTGAAGAAATGGACGTTC
TTTTGGGACAAGAAGTCGGATATTCAATTCGTTTTGAAGATTGCTCTTCACCAAAAACTG
TGTTAAAGTACTTGACCGATGGTATGTTACTGAGAGAAGCAATGTCTGATCCAATGCTTG
AAGCATATCAAGTTATTTTGCTCGACGAAGCGCATGAAAGGACATTAGCCACAGATTTGT
TGATGGGAGTTTTGAAAGAAGTGATTAAACAACGTTCTGATTTGAAATTAGTTATTATGT
CTGCCACATTAGATGCTGGAAAATTTCAAAATTATTTCGATAACGCACCATTGATGAATG
TTCCTGGTCGCACACATCCAGTAGAAATCTTTTATACTCCTGAGCCGGAACGCGACTATT
TGGAGGCTGCAATTAGAACTGTTATTCAAATTCACATGTGTGAAGAAGTCGAAGGTGATA
TCTTGATGTTCTTAACTGGTCAAGAGGAAATCGAAGAAGCATGTAAACGCGTAAAGCGTG
AAATTGATAATTTAGGACCCGATGTCGGTGAACTGAGATGTATTCCCTTGTATTCAACCT
TACCGCCAGCAGCTCAACAGAAAATTTTTGAGCCAGCACCACCAAAAAGAGCGAATGGTG
CTATTGGTCGAAAAGTTGTCATTAGTACAAATATTGCTGAAACATCTCTTACAATTGATG
GAGTTGTGTTTGTAATTGATCCTGGTTTTGCTAAGCAAAAGGTTTATAATCCACGTATTC
GTGTCGAGAGTTTATTAGTTTCGCCTATCAGTAAAGCATCCGCACAGCAACGTGCTGGTC
GTGCTGGACGTACACGTCCTGGAAAATGTTTCAGACTTTATACTGAAAAAGCTTACAAAA
ATGAAATGCAGGATAATACATATCCAGAAATTTTACGTTCAAATTTGGGAACTGTTGTTC
TTCAACTAAAGAAACTTGGCATTGATGATTTAGTTCATTTTGATTTTATGGATCCGCCTG
CACCAGAAACTCTTATGCGTGCTTTGGAGTTATTAAATTATTTGGCAGCACTTGATGACG
ATGGAAACTTGACTGATCTTGGATCTGTTTGTTCTGAATTTCCTCTTGATCCACAATTAG
CAAAAATGTTGATTGCTTCATGTTCACACAACTGCTCTAATGAGATTCTCTCAATTACTG
CAATGTTATCGGGCTTTTGTTAGACCTAATGAAATGAAGAAGCAAGCAGACGATGCCAAG
ATGAGATTTGCACACATCGATGGTGATCATTTGACACTTCTCAATGTATTTCATGCTTTC
AAGCAGAATAATGAAGATCCACAATGGTGTTATGAGAATTTCATCAATTATCGTTCGCTG
AAATCAGCTGATAATGTTCGTCAACAATTGGCTCGTATCATGGACAGATTTAATTTGAAG
CGCACGAGTACAGAGTTCACAAGCAAGGATTATTATGTTAATATTCGTAAAGCACTTGTT
GAAGGATTCTTCATGCAAGTCGCACATTTGGAACGCACTGGTCACTACTTAACAATCAAG
GATAATCAGATTGTTCAATTACATCCATCCACATGCTTAGATCATAAACCAGATTGGGTC
ATTTATAATGAGTTTGTATTAACAACAAAGAATTATATTAGGACAGTAACCGATATTAAA
CCCGAATGGTTATTGAAGCTTGCACCACAATATTACGATCTCAACAATTTCCCAGCATGT
GAGGCAAAGAGACAGTTAGAAAACTTACAAGCAAGGCTAGAGAGTCGTCAATATCAATAT
TAA

>g11211.t60 Gene=g11211 Length=416
MSSKGVACTQPRRVAAMSVAQRVSEEMDVLLGQEVGYSIRFEDCSSPKTVLKYLTDGMLL
REAMSDPMLEAYQVILLDEAHERTLATDLLMGVLKEVIKQRSDLKLVIMSATLDAGKFQN
YFDNAPLMNVPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMCEEVEGDILMFLTGQEEI
EEACKRVKREIDNLGPDVGELRCIPLYSTLPPAAQQKIFEPAPPKRANGAIGRKVVISTN
IAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVSPISKASAQQRAGRAGRTRPGKCF
RLYTEKAYKNEMQDNTYPEILRSNLGTVVLQLKKLGIDDLVHFDFMDPPAPETLMRALEL
LNYLAALDDDGNLTDLGSVCSEFPLDPQLAKMLIASCSHNCSNEILSITAMLSGFC

Protein features from InterProScan

Transcript Database ID Name Start End E.value
13 g11211.t60 CDD cd18791 SF2_C_RHA 135 303 0.000
9 g11211.t60 Gene3D G3DSA:3.40.50.300 - 1 133 0.000
8 g11211.t60 Gene3D G3DSA:3.40.50.300 - 134 316 0.000
10 g11211.t60 Gene3D G3DSA:1.20.120.1080 - 339 414 0.000
3 g11211.t60 PANTHER PTHR18934:SF95 PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX15 4 414 0.000
4 g11211.t60 PANTHER PTHR18934 ATP-DEPENDENT RNA HELICASE 4 414 0.000
1 g11211.t60 Pfam PF00271 Helicase conserved C-terminal domain 156 294 0.000
2 g11211.t60 Pfam PF04408 Helicase associated domain (HA2) 357 413 0.000
12 g11211.t60 ProSiteProfiles PS51192 Superfamilies 1 and 2 helicase ATP-binding type-1 domain profile. 1 131 15.602
11 g11211.t60 ProSiteProfiles PS51194 Superfamilies 1 and 2 helicase C-terminal domain profile. 156 336 16.519
6 g11211.t60 SMART SM00490 helicmild6 178 295 0.000
7 g11211.t60 SMART SM00847 ha2_5 356 416 0.000
5 g11211.t60 SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases 9 413 0.000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0004386 helicase activity MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values