Gene loci information

Transcript annotation

  • This transcript has been annotated as Aspartate–tRNA ligase, cytoplasmic.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_3 g1122 g1122.t6 TTS g1122.t6 8320377 8320377
chr_3 g1122 g1122.t6 isoform g1122.t6 8321201 8323150
chr_3 g1122 g1122.t6 exon g1122.t6.exon1 8321201 8321830
chr_3 g1122 g1122.t6 cds g1122.t6.CDS1 8321203 8321830
chr_3 g1122 g1122.t6 exon g1122.t6.exon2 8321892 8322198
chr_3 g1122 g1122.t6 cds g1122.t6.CDS2 8321892 8321911
chr_3 g1122 g1122.t6 exon g1122.t6.exon3 8322282 8322376
chr_3 g1122 g1122.t6 exon g1122.t6.exon4 8322686 8323150
chr_3 g1122 g1122.t6 TSS g1122.t6 NA NA

Sequences

>g1122.t6 Gene=g1122 Length=1497
ATGCAGCTAATTAAATGCAAATATTTACTAAGATTTTCAATGAAATTATTATTTTCTGAT
GCAAAAGCTGAGTTGTCATTTAATCTTTGTAAAAAAATTGTTAGACTTCTACATGTTAAA
CTGATTCTTCAAGTGCAAACTCTTTATATTTTTAAAATTGGAGTTTTTTTGAATAATTAA
ATATCTTTGATGTACGGGATTATTATAAATAACATGTAATATTAAGTTGTTTTATATTGA
ATACATTAATTAATAATGTCATTTAAGATTTAAGTTATAATTTTTGAAAAACAAAATTAC
TCATAGACATTAATAGTTTCTTTTCGAAAACAACGATAACTCATTTTATTCGGCAATTTT
GCCAACTCGTGAGGAAATTTAGTTTATATAAAAATAGCAGAAAAATAAAACAAATAAGTT
AGTTACACACAATATTATTAAAGACAAAAGTCTATAATAGTGCAACTATGGTAACAGAAG
AATCAACAATAAACAACAATGAAGGCCAGTCAAAAAATGCAGCAAAAAAGCTAGCCGCAA
AAGCAGAAAAGGCAGCAAAGCAGAAAAGAAACAAAAAGAGAATGTTGAAGAAGCAGTTGG
TGAAGATTATTCAAAAGATAAATATGGACAGTCTAAATTGATTCAATCAGGAGAAAAGCA
TCTGGAACGAAATTTCGTACCTGTAGATCAATTAAGTAAAGCAGCAGAAAAAGGCTCAAA
AACTGTGTGGGTTCGCGGACGTATACATACATCTCGATGTAAAGGAAAACAATGTTTTAT
CGTATTACGTCAGCAATCAAGTACTGTGCAAGTGCTTATTTCTGTTAATGACGTCATTTC
GAAGCAAATGGTTAAATTCTCTGGATCAATTGCCCGTGAGAGTATCGTTGATATTCATGC
GAATATCGTCAAAGTTGAACAAAAAATAGAATCATGTACAGAACAAAATTTGGAACTGCA
TGGTTTAGAAATTTACGTTGTTTCACCAGCAAAACCGCAACTGCCACTTCAAATTGAAGA
TGCTTCGCGTCCAGAAAAGAATGATGACCCAGACAGTCTTAAAATTCGTGTTAATCAAGA
TACTCGCTTAGATAATCGTGTATTAGATTTACGTACTCCAGCGAATCAGGCTATTTTCAG
ATTAGAAGCTGGCGTTTGTAAACTCTTTCGCGACATTCTGAGTAAAAAAGGTTTTGTTGA
GATCCACACACCTAAAATCATTTCAGCTGCGAGTGAAGGAGGAGCAAATGTTTTTACAGT
TAGCTATTTTAAAGAATCAGCATACCTTGCACAATCACCACAATTGTACAAGCAAATGGC
TATTGCAGCTGACTTTGATCGAGTTTTTACGGTTGGAGCAGTTTTTCGAGCAGAAGACTC
CAACACACATCGACATTTGACTGAATTCGTTGGCTTAGATTTAGAAATGGCCTTCAAATA
TCATTACCATGAAGTGCTGGACACAATTGCAAATACATTTACTGAAATGTTTAAAGG

>g1122.t6 Gene=g1122 Length=216
MVKFSGSIARESIVDIHANIVKVEQKIESCTEQNLELHGLEIYVVSPAKPQLPLQIEDAS
RPEKNDDPDSLKIRVNQDTRLDNRVLDLRTPANQAIFRLEAGVCKLFRDILSKKGFVEIH
TPKIISAASEGGANVFTVSYFKESAYLAQSPQLYKQMAIAADFDRVFTVGAVFRAEDSNT
HRHLTEFVGLDLEMAFKYHYHEVLDTIANTFTEMFK

Protein features from InterProScan

Transcript Database ID Name Start End E.value
8 g1122.t6 Gene3D G3DSA:2.40.50.140 - 1 52 0.0000000
7 g1122.t6 Gene3D G3DSA:3.30.930.10 Bira Bifunctional Protein; Domain 2 53 216 0.0000000
2 g1122.t6 PANTHER PTHR43450 ASPARTYL-TRNA SYNTHETASE 1 216 0.0000000
3 g1122.t6 PRINTS PR01042 Aspartyl-tRNA synthetase signature 147 159 0.0000002
4 g1122.t6 PRINTS PR01042 Aspartyl-tRNA synthetase signature 164 177 0.0000002
1 g1122.t6 Pfam PF00152 tRNA synthetases class II (D, K and N) 77 216 0.0000000
9 g1122.t6 ProSiteProfiles PS50862 Aminoacyl-transfer RNA synthetases class-II family profile. 97 216 12.7260000
6 g1122.t6 SUPERFAMILY SSF50249 Nucleic acid-binding proteins 1 52 0.0000022
5 g1122.t6 SUPERFAMILY SSF55681 Class II aaRS and biotin synthetases 72 215 0.0000000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006422 aspartyl-tRNA aminoacylation BP
GO:0005524 ATP binding MF
GO:0006418 tRNA aminoacylation for protein translation BP
GO:0000166 nucleotide binding MF
GO:0004815 aspartate-tRNA ligase activity MF
GO:0004812 aminoacyl-tRNA ligase activity MF
GO:0005737 cytoplasm CC

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values