General information for g11247.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Probable cytochrome P450 313a4.
Parent gene
- The parent gene g11247 is located on chr_1: 14901911..14903568 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11247 | g11247.t1 | isoform | g11247.t1 | 14901911 | 14903568 |
| chr_1 | g11247 | g11247.t1 | exon | g11247.t1.exon1 | 14901911 | 14902101 |
| chr_1 | g11247 | g11247.t1 | cds | g11247.t1.CDS1 | 14901911 | 14902101 |
| chr_1 | g11247 | g11247.t1 | exon | g11247.t1.exon2 | 14902171 | 14902570 |
| chr_1 | g11247 | g11247.t1 | cds | g11247.t1.CDS2 | 14902171 | 14902570 |
| chr_1 | g11247 | g11247.t1 | exon | g11247.t1.exon3 | 14902633 | 14902894 |
| chr_1 | g11247 | g11247.t1 | cds | g11247.t1.CDS3 | 14902633 | 14902894 |
| chr_1 | g11247 | g11247.t1 | exon | g11247.t1.exon4 | 14902952 | 14903568 |
| chr_1 | g11247 | g11247.t1 | cds | g11247.t1.CDS4 | 14902952 | 14903568 |
| chr_1 | g11247 | g11247.t1 | TSS | g11247.t1 | NA | NA |
| chr_1 | g11247 | g11247.t1 | TTS | g11247.t1 | NA | NA |
Sequences
>g11247.t1 Gene=g11247 Length=1470
ATGAATTTGACAGAAATATTATTGGTATTTCTCATATCAACTCTAATTGCGTATAGTTTG
AAATATTTGTGGAGTTGGTGGAAATTTCTTGTGTTGGCAAGCAAAATACCAAGTGTTAAA
TTTGAAATTCCTCTAATTGGAATATTAATTGATTTTCTTTTTATTAAATTTGAAGATTAT
TTGCCATTGATAGTTAATTTTTTTGAAGAAAGCCCAAGTATAAGTAGAAAATGGATGGGA
TCAAAATTGATTGTGCTTGTGAATTCACCTGAAAATGTTCAGGTTGTATTAAATTCACCT
CATTGCAATAAACGCCCACCAATATTTTATGAAGCTTATCTTGCAACAGAAGGTTTAGTT
TTAATCAACGGTCAGAAATGGGAGCATCATAGAAAAATTCTGAAAAATTCTTTTTCTTCA
CAAATGTTGCAAAATATTATTCCAATTTTCGATGAAAGATCAAGTCATTATATTAAAAGA
TTAAATGAAAAAGTCGATTGTGACGATTTTGACATTTACCAAATTGTTGCTGGATGTACA
CTCGAGTCATTGCTTCAAGGCAATCTTAACATGACACGAGATTTCTATGAAAACGAATAT
TTTGATGATGTTGAAAAACTCAAGCACTGCACAATGGAGCGAATGTTCCAACCATGGCTT
GGATATGAAAAGTTATATAAAATGACAAAACTTTATAAAAAGTGTCATCAAGCATACGCT
AGCACAGTGGCTTTAGCAGATGAAGTTGTAAATGCAAATCATCACTTGCGAATCGCTGAC
GAGTTGAAGAATCGAAACGTGATAAGTCAACTATTAAATGTGAGAAACAACTTTACAGAC
AACGAAATTAAGGATGAACTAATCACATTCATCATTGTCGCTCATGAGACAACAGCACTT
ACTTTATCAGGTGTCATATTAATGCTCGCAATTCACAAAGATGTGCAGGAAAAAGTTTTT
AGTGAAATTAGAGAAGTAGTTAATTCAAATGAGGGAATGATTGACATTGAAACACTTCAC
AAGCTCACATATTTAGAAATGGTGATCAAAGAAACTATGCGAATATTTCCCGTCGTTCCT
GCATTTGGTAGAGAAGCAACAGATGAATTTAAGCTAGAAGATTTCGTAATACCAAAAGGA
ACTTTGCTGATTTCATCAATTTTCTCTCTACATCGAAATACAAAATATTGGGGTGAGGAT
GCGCATCTGTTTAAGCCAGAGAGATTTAGAACTGAAAATTTAAAGAAAATCCATCCCTAT
GCTTTTATTCCATTCACTGGTGGTAGAAGGATCTGTCTGGGATGGAAATACACGATGCTG
TTTAAGAAAGCATTTCTAATACATTTCCTAAGAGCATTTGAGGTGAATACAAAATTAAAG
TTCAATGAACTTAAAGTAAACATGACGCCAACTGTAGCAATAGAACAAAATTACATGATA
AGTATAAAGAAGAGGCAGCTTGTTAAATAA
>g11247.t1 Gene=g11247 Length=489
MNLTEILLVFLISTLIAYSLKYLWSWWKFLVLASKIPSVKFEIPLIGILIDFLFIKFEDY
LPLIVNFFEESPSISRKWMGSKLIVLVNSPENVQVVLNSPHCNKRPPIFYEAYLATEGLV
LINGQKWEHHRKILKNSFSSQMLQNIIPIFDERSSHYIKRLNEKVDCDDFDIYQIVAGCT
LESLLQGNLNMTRDFYENEYFDDVEKLKHCTMERMFQPWLGYEKLYKMTKLYKKCHQAYA
STVALADEVVNANHHLRIADELKNRNVISQLLNVRNNFTDNEIKDELITFIIVAHETTAL
TLSGVILMLAIHKDVQEKVFSEIREVVNSNEGMIDIETLHKLTYLEMVIKETMRIFPVVP
AFGREATDEFKLEDFVIPKGTLLISSIFSLHRNTKYWGEDAHLFKPERFRTENLKKIHPY
AFIPFTGGRRICLGWKYTMLFKKAFLIHFLRAFEVNTKLKFNELKVNMTPTVAIEQNYMI
SIKKRQLVK
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 13 | g11247.t1 | Gene3D | G3DSA:1.10.630.10 | Cytochrome p450 | 21 | 489 | 2.7E-92 |
| 2 | g11247.t1 | PANTHER | PTHR24291:SF145 | CYTOCHROME P450 4AA1-RELATED | 21 | 469 | 5.4E-78 |
| 3 | g11247.t1 | PANTHER | PTHR24291 | CYTOCHROME P450 FAMILY 4 | 21 | 469 | 5.4E-78 |
| 8 | g11247.t1 | PRINTS | PR00385 | P450 superfamily signature | 293 | 310 | 4.3E-7 |
| 6 | g11247.t1 | PRINTS | PR00463 | E-class P450 group I signature | 302 | 328 | 1.3E-8 |
| 4 | g11247.t1 | PRINTS | PR00463 | E-class P450 group I signature | 346 | 364 | 1.3E-8 |
| 9 | g11247.t1 | PRINTS | PR00385 | P450 superfamily signature | 347 | 358 | 4.3E-7 |
| 7 | g11247.t1 | PRINTS | PR00463 | E-class P450 group I signature | 422 | 432 | 1.3E-8 |
| 10 | g11247.t1 | PRINTS | PR00385 | P450 superfamily signature | 423 | 432 | 4.3E-7 |
| 5 | g11247.t1 | PRINTS | PR00463 | E-class P450 group I signature | 432 | 455 | 1.3E-8 |
| 1 | g11247.t1 | Pfam | PF00067 | Cytochrome P450 | 43 | 460 | 1.8E-78 |
| 16 | g11247.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 5 | - |
| 18 | g11247.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 6 | 27 | - |
| 14 | g11247.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 28 | 38 | - |
| 17 | g11247.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 39 | 57 | - |
| 15 | g11247.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 58 | 489 | - |
| 12 | g11247.t1 | SUPERFAMILY | SSF48264 | Cytochrome P450 | 41 | 485 | 2.62E-93 |
| 11 | g11247.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 7 | 26 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0020037 | heme binding | MF |
| GO:0016705 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | MF |
| GO:0005506 | iron ion binding | MF |
| GO:0055114 | NA | NA |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed