General information for g11263.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Type II inositol 1,4,5-trisphosphate 5-phosphatase.
Parent gene
- The parent gene g11263 is located on chr_1: 15158026..15159937 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11263 | g11263.t5 | isoform | g11263.t5 | 15156456 | 15158406 |
| chr_1 | g11263 | g11263.t5 | exon | g11263.t5.exon1 | 15156456 | 15156457 |
| chr_1 | g11263 | g11263.t5 | exon | g11263.t5.exon2 | 15156522 | 15157850 |
| chr_1 | g11263 | g11263.t5 | cds | g11263.t5.CDS1 | 15156824 | 15157850 |
| chr_1 | g11263 | g11263.t5 | exon | g11263.t5.exon3 | 15157905 | 15158406 |
| chr_1 | g11263 | g11263.t5 | cds | g11263.t5.CDS2 | 15157905 | 15158026 |
| chr_1 | g11263 | g11263.t5 | TSS | g11263.t5 | NA | NA |
| chr_1 | g11263 | g11263.t5 | TTS | g11263.t5 | NA | NA |
Sequences
>g11263.t5 Gene=g11263 Length=1833
TGATCAAATATTTTGGATAGGCGATCTCAATTATCGTATTGCAACAGCAATTGATGATGG
GCAAATAAAAAATTTTTGCGAATATGAAAAACTTTTTTATCTTGATCAATTGTATATTGA
ACACGTAAAGAAAAAGAGAGTATTTCGTGATTTTCAAGAAGGTAAAATTACATTTAAACC
AACTTATAAATATGATCCTGGAACAGATGAATGGGATTCGAGTGAAAAAAATAGAGCACC
AGCATGGTGTGATAGAATCTTTTGGAAAGGTCAAAAAGTAGAACAATTATGTTATAAAAG
TGTAATGCAATTGAGAATAAGTGATCATAAACCGGTCTATAGTGTTTTTATCACATATAT
AATGACGCGTGATGAGAAAAAGTTTAAGAGAGTGCATGAAGAAGTGCTAAAAACTGTTGA
TAAATATGAAAATGATAATCAACCACAAATGACTGTTGCAGAAACTGACCTCGATTTTGG
CATATTAAGATATCATGAAATGTATAGTCGAGAATTGTTAGTTGCAAATAATTGTCATTT
ACCTGTTCATTTTAAATTTTTATCTAAGGACATTGTCAGTTCAAGTGTTTGTGAAGATTG
GATAAGAATATCTCATAAAAGTGGTGAATTATTGACAGGAAACTCAATGAGCATTCGCAT
AGACATTTTTATAGATGAGAGTTCAGCATCAAAAATAATGCGAAGATTAAAAGATGCACA
AATTAATGTCAAAGTACCACTCGATATTCTTGTTCTTCATGTAGAAAATGGAAGAGATAT
TTTTATAACAGTTTTTGGTGAATATCAACCAAGTATTTTCGGTTTACGATTAGATACATT
GATGAAATTAAATAAATCTGTTCTTGAATATTCTTTGAAAGAATTGATGGATATTGATGA
TGATGCCAATAATTTAATTCCATTTTATAACAATGCAAAAGCACCCCGTGAAATTTATTT
AATGATTGACTATTTATATCGAAACGGTCTAAATATCCCACATCTATTTACAATACAAAG
ACGACATAAATTGAGTCCGCGTATTTGTGCAATAAGAGACTGGCTTGATTCATGGTCAGT
TGAAAATTTTCCTGGAACACCACAAACTGCTGCCGAAATTCTTTTAAAAATATTTGAAGC
CTCACCTGAGCCACTTGTTACAATCACAGAACGTGAATTACAAATTTATGTTCAATATTT
TGACAGATGCAAAGAGTTAGTTCAGAATAAGATGCCACTGCTCAACCGTAAAATATTTCT
CTATGTTATCATGTTTCTTAAAGAAATTCAAAAGAATTATACCATTAATGGGATGGATGA
TAGAACTATTGCAAAAATCTTTGCACCTGCTTTATGTCGACATCAAAATGATCAATTTAG
TCAGAAATTTCTACTTCTGTTTTTATCAAATGACATTAAAGATTTTGCACGAGTTGAACT
CGAAAAAAATTGAGCATCATCATAACAACAATTCTGGTTACGGCATGAAAGAATGTTTAG
CCACTAGAAATGAATTTTATTTCTGTACGTACTTATACTTAATTTCTGTTCTTTCTGTTA
ATCTTTTAAACATTCCTCTTCTAAATATACATGAATAGTGCATGTATGAATCAATTATTT
AATTTTTCTTTCTGTATATCAACTATTTAGTTTTAACATCAACTACGGTAATTCTCAAAA
ATGTAAAAAAAACATGAAAGCAATTTTATTCAGTCATGAAATCTTCTTTTAAGTAAAAGA
ATTTAATAAAATTATTACTCTTTACAATTTCAACATAAAATGAGTGAATTTTCATTTTTT
AAATCTTACAAAATTACAAGCAAATGTGTATTC
>g11263.t5 Gene=g11263 Length=382
MQLRISDHKPVYSVFITYIMTRDEKKFKRVHEEVLKTVDKYENDNQPQMTVAETDLDFGI
LRYHEMYSRELLVANNCHLPVHFKFLSKDIVSSSVCEDWIRISHKSGELLTGNSMSIRID
IFIDESSASKIMRRLKDAQINVKVPLDILVLHVENGRDIFITVFGEYQPSIFGLRLDTLM
KLNKSVLEYSLKELMDIDDDANNLIPFYNNAKAPREIYLMIDYLYRNGLNIPHLFTIQRR
HKLSPRICAIRDWLDSWSVENFPGTPQTAAEILLKIFEASPEPLVTITERELQIYVQYFD
RCKELVQNKMPLLNRKIFLYVIMFLKEIQKNYTINGMDDRTIAKIFAPALCRHQNDQFSQ
KFLLLFLSNDIKDFARVELEKN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g11263.t5 | Gene3D | G3DSA:3.60.10.10 | - | 1 | 47 | 0.000007 |
| 6 | g11263.t5 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 48 | 181 | 0.000000 |
| 8 | g11263.t5 | Gene3D | G3DSA:1.10.555.10 | - | 213 | 373 | 0.000000 |
| 2 | g11263.t5 | PANTHER | PTHR11200 | INOSITOL 5-PHOSPHATASE | 1 | 260 | 0.000000 |
| 3 | g11263.t5 | PANTHER | PTHR11200:SF163 | TYPE II INOSITOL 1,4,5-TRISPHOSPHATE 5-PHOSPHATASE | 1 | 260 | 0.000000 |
| 1 | g11263.t5 | Pfam | PF00620 | RhoGAP domain | 214 | 356 | 0.000000 |
| 9 | g11263.t5 | ProSiteProfiles | PS50238 | Rho GTPase-activating proteins domain profile. | 195 | 382 | 15.116000 |
| 5 | g11263.t5 | SMART | SM00324 | RhoGAP_3 | 211 | 379 | 0.000027 |
| 4 | g11263.t5 | SUPERFAMILY | SSF48350 | GTPase activation domain, GAP | 168 | 359 | 0.000000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0007165 | signal transduction | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
