General information for g11283.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Cathepsin L-like.
Parent gene
- The parent gene g11283 is located on chr_1: 15356489..15357600 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11283 | g11283.t1 | isoform | g11283.t1 | 15356489 | 15357600 |
| chr_1 | g11283 | g11283.t1 | exon | g11283.t1.exon1 | 15356489 | 15357448 |
| chr_1 | g11283 | g11283.t1 | cds | g11283.t1.CDS1 | 15356489 | 15357448 |
| chr_1 | g11283 | g11283.t1 | exon | g11283.t1.exon2 | 15357502 | 15357600 |
| chr_1 | g11283 | g11283.t1 | cds | g11283.t1.CDS2 | 15357502 | 15357600 |
| chr_1 | g11283 | g11283.t1 | TSS | g11283.t1 | NA | NA |
| chr_1 | g11283 | g11283.t1 | TTS | g11283.t1 | NA | NA |
Sequences
>g11283.t1 Gene=g11283 Length=1059
ATGGTCAAATTAGTTTTTGTGATTTTTATTGCAATTTGTGCAGTTGCTGTAGCAAAGTTG
TCGGCAGATGAAGAAAATGAGCTATTTGAAAACTATTTGAAAAAATTCAACATCACTGAT
AATCAATTGAATGTCCATATGTACTCAAGCTCAAGTCAACCTTCGAAGAAGAAAAAAAGC
TCTAAAGAAATTTTCTTAGAAAAATATTACGCAATTGAGGAACACAATGAACGCTATAGA
AATGGTGATGAGACTTATCAGCAAGTAATTCATCCGTATTCACATTTATCGCATGATGAT
TTCCTAAGATATCGGACGGGTCTGACTTCTTTTTTAAGAATATCTGAGAAAAAGTCGAAC
AACTTTACAATTGATTTGAAATTCACGCTGCCGGACAATTTTAACTGGGTTCAAAGTGGC
GTTGTTAGGCCCGTGCAAAATCAAGGACTTTGTCAATGTTCTTATGCTTTTGCGACTGTT
GGAGCAATCGAAGGTCAATTGTCGCTTTTAGGCAATAATTCGAAACTTTCAGAGCAAGAA
GTGGTCGATTGTGCTCGATATTATCTATTCTTTGTCATTCCAATTGTTCTCGGTTGTGAT
GGTGGCAATGATGTCGCAGTCTATGACTATGCGAAAAAATACAATGGTTTGACAACTGCT
GAAATTTATCCATATCAGGGCAAGGTCAATCGATGCCAAACGAATCGACCTAAAGTACAG
GGATCGAAAGTGAGGAGTTTTGTTGATGTTCCAGCCGATGAGGAAGCTATGAAACAAATT
CTCTATACACGTGGGCCTTTATATGTGACAATCTATGCATCACCTACTTTTGCATCATAC
ACAAGTGGAATTTACACAGATTCACTAGGCGAATGCGATAACATGAAGAGCAACCATGCA
CTTTTGTTAGTTGGCTATGGTGAGGAAGCTGATCAAGATTATTGGATATTAAAAAACAGT
TGGGGAGAATCATATGGTGAAAATGGTTATGTCAGAATCTCTCGTGGTGTTAATCTTTGT
AATATTGCTAAAGATGCGTCATATCCGAATCTTTATTGA
>g11283.t1 Gene=g11283 Length=352
MVKLVFVIFIAICAVAVAKLSADEENELFENYLKKFNITDNQLNVHMYSSSSQPSKKKKS
SKEIFLEKYYAIEEHNERYRNGDETYQQVIHPYSHLSHDDFLRYRTGLTSFLRISEKKSN
NFTIDLKFTLPDNFNWVQSGVVRPVQNQGLCQCSYAFATVGAIEGQLSLLGNNSKLSEQE
VVDCARYYLFFVIPIVLGCDGGNDVAVYDYAKKYNGLTTAEIYPYQGKVNRCQTNRPKVQ
GSKVRSFVDVPADEEAMKQILYTRGPLYVTIYASPTFASYTSGIYTDSLGECDNMKSNHA
LLLVGYGEEADQDYWILKNSWGESYGENGYVRISRGVNLCNIAKDASYPNLY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 16 | g11283.t1 | CDD | cd02248 | Peptidase_C1A | 131 | 349 | 3.08019E-88 |
| 10 | g11283.t1 | Gene3D | G3DSA:3.90.70.10 | Cysteine proteinases | 21 | 351 | 8.0E-84 |
| 2 | g11283.t1 | PANTHER | PTHR12411 | CYSTEINE PROTEASE FAMILY C1-RELATED | 41 | 347 | 1.3E-56 |
| 3 | g11283.t1 | PANTHER | PTHR12411:SF57 | CATHEPSIN L1 | 41 | 347 | 1.3E-56 |
| 6 | g11283.t1 | PRINTS | PR00705 | Papain cysteine protease (C1) family signature | 148 | 163 | 9.0E-6 |
| 4 | g11283.t1 | PRINTS | PR00705 | Papain cysteine protease (C1) family signature | 299 | 309 | 9.0E-6 |
| 5 | g11283.t1 | PRINTS | PR00705 | Papain cysteine protease (C1) family signature | 314 | 320 | 9.0E-6 |
| 1 | g11283.t1 | Pfam | PF00112 | Papain family cysteine protease | 130 | 349 | 3.7E-62 |
| 12 | g11283.t1 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 22 | - |
| 13 | g11283.t1 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 3 | - |
| 14 | g11283.t1 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 4 | 15 | - |
| 15 | g11283.t1 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 16 | 22 | - |
| 11 | g11283.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 23 | 352 | - |
| 19 | g11283.t1 | ProSitePatterns | PS00639 | Eukaryotic thiol (cysteine) proteases histidine active site. | 297 | 307 | - |
| 18 | g11283.t1 | ProSitePatterns | PS00640 | Eukaryotic thiol (cysteine) proteases asparagine active site. | 314 | 333 | - |
| 20 | g11283.t1 | SMART | SM00645 | pept_c1 | 130 | 350 | 6.5E-70 |
| 7 | g11283.t1 | SUPERFAMILY | SSF54001 | Cysteine proteinases | 54 | 349 | 2.85E-79 |
| 9 | g11283.t1 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 18 | - |
| 17 | g11283.t1 | SignalP_GRAM_NEGATIVE | SignalP-noTM | SignalP-noTM | 1 | 18 | - |
| 8 | g11283.t1 | SignalP_GRAM_POSITIVE | SignalP-TM | SignalP-TM | 1 | 22 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0008234 | cysteine-type peptidase activity | MF |
| GO:0006508 | proteolysis | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed