Gene loci information

Transcript annotation

  • This transcript has been annotated as Cullin-1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g11288 g11288.t6 isoform g11288.t6 15426223 15429885
chr_1 g11288 g11288.t6 exon g11288.t6.exon1 15426223 15426743
chr_1 g11288 g11288.t6 cds g11288.t6.CDS1 15426308 15426743
chr_1 g11288 g11288.t6 exon g11288.t6.exon2 15429077 15429494
chr_1 g11288 g11288.t6 cds g11288.t6.CDS2 15429077 15429150
chr_1 g11288 g11288.t6 exon g11288.t6.exon3 15429555 15429646
chr_1 g11288 g11288.t6 exon g11288.t6.exon4 15429873 15429885
chr_1 g11288 g11288.t6 TSS g11288.t6 NA NA
chr_1 g11288 g11288.t6 TTS g11288.t6 NA NA

Sequences

>g11288.t6 Gene=g11288 Length=1044
AGTCCTCATTCATAAACACTTAGACGCTTTTCGTGTTGAATTTCAAAATTTGTTAAATGC
TGACAAGAATGAAGATTTAGCGAGAATGTATATGCTTGTGTCTCGTACAGCTGATGGGCT
TGCAGATCTGAAAATTGCTCTTGAGAATCACATAAATAATCAAGGCCAACAAGCAATTGA
TAAATGCGGAGAAGCAGCTGCTAATGATCCTAAAATATACGTTCAGACTATTCTTGAAGT
ACACATGAAATTCAATAGTCTTGTAATGACTGCTTTCAACAATGATAGTGGTTTTGTTGC
CGCATTAGATAAAGCATGCAACAAATTCATCAATTCAAATTGCGTTACGCAAGCCAGTAA
GAACGAAAGTCGTTCACCTGAGTTGCTGGCCAAATATTGTGATATTTTATTGAAAAAGAG
CAGCAAAAATCCAGAAGAAGCAGAGCTTGAAGATACTCTAAATCATGTTATGATTGTTTT
CAAATATATAACCGATAAAGATGTATTTCAGAAATTTTACAAATATTCATGTTTTATGAT
AGATGTTTTATTTTTATCATTTCAGAACAATTTGAGATGTTTGATTGTTCATTGAAACGG
AATAAATCGCTTAGGCTATTGAGCCAGCATTTGATGCAATACGGGGCCATAAATCTGCAC
ACTCTTTTGCAACTGGACCTGTAATAGCTGATCCTTTCATTTCACCTTTATTGTTGACAA
TTACACCGGCGTTATCTTCAAAATAGATAAAGATTCCATCTCGTCGTCTGAACGGTTTTC
GCTGCCGAATGACAACTGCTGGCATTACTTTCTTTCTCAATTCTGGTTTACCCTTCTTTA
CAGTTGCGACAAACATGTCACCAACACCAGCTGAAGGTAAACGATTCAAACGACCGCGAA
TGCCATGAACAGCAATAACATACAAGTTTTTACCACCTATGTATTATCTGCACAATTAAT
TACTGCGCCAACAGGCATACCGAGTGAAATACGGAATTTTCCTCCCGCGGAACCTCCACG
ACCTAAAAAAACTCTCTTCGACAT

>g11288.t6 Gene=g11288 Length=169
MYMLVSRTADGLADLKIALENHINNQGQQAIDKCGEAAANDPKIYVQTILEVHMKFNSLV
MTAFNNDSGFVAALDKACNKFINSNCVTQASKNESRSPELLAKYCDILLKKSSKNPEEAE
LEDTLNHVMIVFKYITDKDVFQKFYKYSCFMIDVLFLSFQNNLRCLIVH

Protein features from InterProScan

Transcript Database ID Name Start End E.value
6 g11288.t6 Gene3D G3DSA:1.20.1310.10 Cullin Repeats 1 93 0.000
7 g11288.t6 Gene3D G3DSA:1.20.1310.10 Cullin Repeats 94 149 0.000
2 g11288.t6 PANTHER PTHR11932 CULLIN 1 146 0.000
3 g11288.t6 PANTHER PTHR11932:SF81 CULLIN-1 1 146 0.000
1 g11288.t6 Pfam PF00888 Cullin family 1 146 0.000
8 g11288.t6 ProSiteProfiles PS50069 Cullin family profile. 96 146 17.359
4 g11288.t6 SUPERFAMILY SSF74788 Cullin repeat-like 1 87 0.000
5 g11288.t6 SUPERFAMILY SSF75632 Cullin homology domain 93 146 0.000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006511 ubiquitin-dependent protein catabolic process BP
GO:0031625 ubiquitin protein ligase binding MF

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values