General information for g11495.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Proteasome subunit alpha type-3.
Parent gene
- The parent gene g11495 is located on chr_1: 16626368..16627254 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11495 | g11495.t1 | TSS | g11495.t1 | 16626322 | 16626322 |
| chr_1 | g11495 | g11495.t1 | isoform | g11495.t1 | 16626368 | 16627254 |
| chr_1 | g11495 | g11495.t1 | exon | g11495.t1.exon1 | 16626368 | 16626388 |
| chr_1 | g11495 | g11495.t1 | cds | g11495.t1.CDS1 | 16626368 | 16626388 |
| chr_1 | g11495 | g11495.t1 | exon | g11495.t1.exon2 | 16626447 | 16626653 |
| chr_1 | g11495 | g11495.t1 | cds | g11495.t1.CDS2 | 16626447 | 16626653 |
| chr_1 | g11495 | g11495.t1 | exon | g11495.t1.exon3 | 16626718 | 16627254 |
| chr_1 | g11495 | g11495.t1 | cds | g11495.t1.CDS3 | 16626718 | 16627254 |
| chr_1 | g11495 | g11495.t1 | TTS | g11495.t1 | 16627359 | 16627359 |
Sequences
>g11495.t1 Gene=g11495 Length=765
ATGAGTTCAATTGGTACAGGATATGATTTGAGTGCAAGTCAATTTTCGCCGGATGGTCGA
GTTTTTCAAGTCGAATATGCAATGAAAGCTGCTGAAATTTCCGGCACTGCTATTGGTTTA
AGAGGGAAAGATGGTTGTATTTTAGCAGTAGAAAAAGTCATAACTAGCAAATTGCACGAA
CCTGATTCGGGCAGAAGAATCTTTACGATTGAAAACTCAATAGGAATGGTAATTTGCGGT
CTCATTACAGACGGACGCGCAATTGTAAATTATGCATTGAAAGAAGCTCAAAATTATCGC
AGAGAGTATGGACAAACTATTCCATTGAAGATTTTGAATGAGAGACTCTCTAGCTTATTT
CATGCATATACACTATACAGTGCAGTTCGACCTTATGGCATTTGCATTATTCTCACAACA
TGGACTGAGCAAAATGGTGCTGAAATGTATTGTATTGAACCATCAGGCGTTTCTTTTGGA
TATTATGGATGCGCCACAGGAAAAGCAAAACAAGCCGCTAAAACTGAAATCGAAAAGCTT
AAACTGAATACACTTACAGCTCGTGAGTTATTAAATGAAGGAGCGAAAATTATTTATCGT
GTGAACGAAGATTCAAGCGATAGTGATACAAAATTCAAGCTAGAATTATCATGGGTTGGA
AAAGACACAAATGGAATTCATCAAATCTGTCCGGTCAATTTATATGAAGAAGCGAAAGCA
GCTGCAACTGCTGCAATGGAACAAGGTGACAGTGATGTTGAATAA
>g11495.t1 Gene=g11495 Length=254
MSSIGTGYDLSASQFSPDGRVFQVEYAMKAAEISGTAIGLRGKDGCILAVEKVITSKLHE
PDSGRRIFTIENSIGMVICGLITDGRAIVNYALKEAQNYRREYGQTIPLKILNERLSSLF
HAYTLYSAVRPYGICIILTTWTEQNGAEMYCIEPSGVSFGYYGCATGKAKQAAKTEIEKL
KLNTLTARELLNEGAKIIYRVNEDSSDSDTKFKLELSWVGKDTNGIHQICPVNLYEEAKA
AATAAMEQGDSDVE
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g11495.t1 | CDD | cd03751 | proteasome_alpha_type_3 | 5 | 219 | 1.45616E-116 |
| 6 | g11495.t1 | Gene3D | G3DSA:3.60.20.10 | Glutamine Phosphoribosylpyrophosphate | 1 | 250 | 1.2E-73 |
| 3 | g11495.t1 | PANTHER | PTHR11599:SF10 | PROTEASOME SUBUNIT ALPHA TYPE-3 | 1 | 250 | 8.0E-94 |
| 4 | g11495.t1 | PANTHER | PTHR11599 | PROTEASOME SUBUNIT ALPHA/BETA | 1 | 250 | 8.0E-94 |
| 2 | g11495.t1 | Pfam | PF10584 | Proteasome subunit A N-terminal signature | 8 | 30 | 2.9E-13 |
| 1 | g11495.t1 | Pfam | PF00227 | Proteasome subunit | 35 | 212 | 3.7E-41 |
| 8 | g11495.t1 | ProSitePatterns | PS00388 | Proteasome alpha-type subunits signature. | 8 | 30 | - |
| 10 | g11495.t1 | ProSiteProfiles | PS51475 | Proteasome alpha-type subunit profile. | 23 | 239 | 58.274 |
| 9 | g11495.t1 | SMART | SM00948 | Proteasome_A_N_2 | 8 | 30 | 2.3E-9 |
| 5 | g11495.t1 | SUPERFAMILY | SSF56235 | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 6 | 229 | 3.87E-63 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0019773 | proteasome core complex, alpha-subunit complex | CC |
| GO:0051603 | proteolysis involved in cellular protein catabolic process | BP |
| GO:0006511 | ubiquitin-dependent protein catabolic process | BP |
| GO:0005839 | proteasome core complex | CC |
KEGG
Orthology
- This transcript has been annotated with K02727 (20S proteasome subunit alpha 7)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
