Gene loci information

Transcript annotation

  • This transcript has been annotated as Proteasome subunit alpha type-3.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g11495 g11495.t3 TSS g11495.t3 16626322 16626322
chr_1 g11495 g11495.t3 isoform g11495.t3 16626368 16627254
chr_1 g11495 g11495.t3 exon g11495.t3.exon1 16626368 16626380
chr_1 g11495 g11495.t3 exon g11495.t3.exon2 16626447 16626653
chr_1 g11495 g11495.t3 cds g11495.t3.CDS1 16626507 16626653
chr_1 g11495 g11495.t3 exon g11495.t3.exon3 16626718 16627254
chr_1 g11495 g11495.t3 cds g11495.t3.CDS2 16626718 16627254
chr_1 g11495 g11495.t3 TTS g11495.t3 16627359 16627359

Sequences

>g11495.t3 Gene=g11495 Length=757
ATGAGTTCAATTGTATGATTTGAGTGCAAGTCAATTTTCGCCGGATGGTCGAGTTTTTCA
AGTCGAATATGCAATGAAAGCTGCTGAAATTTCCGGCACTGCTATTGGTTTAAGAGGGAA
AGATGGTTGTATTTTAGCAGTAGAAAAAGTCATAACTAGCAAATTGCACGAACCTGATTC
GGGCAGAAGAATCTTTACGATTGAAAACTCAATAGGAATGGTAATTTGCGGTCTCATTAC
AGACGGACGCGCAATTGTAAATTATGCATTGAAAGAAGCTCAAAATTATCGCAGAGAGTA
TGGACAAACTATTCCATTGAAGATTTTGAATGAGAGACTCTCTAGCTTATTTCATGCATA
TACACTATACAGTGCAGTTCGACCTTATGGCATTTGCATTATTCTCACAACATGGACTGA
GCAAAATGGTGCTGAAATGTATTGTATTGAACCATCAGGCGTTTCTTTTGGATATTATGG
ATGCGCCACAGGAAAAGCAAAACAAGCCGCTAAAACTGAAATCGAAAAGCTTAAACTGAA
TACACTTACAGCTCGTGAGTTATTAAATGAAGGAGCGAAAATTATTTATCGTGTGAACGA
AGATTCAAGCGATAGTGATACAAAATTCAAGCTAGAATTATCATGGGTTGGAAAAGACAC
AAATGGAATTCATCAAATCTGTCCGGTCAATTTATATGAAGAAGCGAAAGCAGCTGCAAC
TGCTGCAATGGAACAAGGTGACAGTGATGTTGAATAA

>g11495.t3 Gene=g11495 Length=227
MKAAEISGTAIGLRGKDGCILAVEKVITSKLHEPDSGRRIFTIENSIGMVICGLITDGRA
IVNYALKEAQNYRREYGQTIPLKILNERLSSLFHAYTLYSAVRPYGICIILTTWTEQNGA
EMYCIEPSGVSFGYYGCATGKAKQAAKTEIEKLKLNTLTARELLNEGAKIIYRVNEDSSD
SDTKFKLELSWVGKDTNGIHQICPVNLYEEAKAAATAAMEQGDSDVE

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g11495.t3 Gene3D G3DSA:3.60.20.10 Glutamine Phosphoribosylpyrophosphate 1 227 0.000
2 g11495.t3 PANTHER PTHR11599:SF10 PROTEASOME SUBUNIT ALPHA TYPE-3 1 223 0.000
3 g11495.t3 PANTHER PTHR11599 PROTEASOME SUBUNIT ALPHA/BETA 1 223 0.000
1 g11495.t3 Pfam PF00227 Proteasome subunit 8 185 0.000
6 g11495.t3 ProSiteProfiles PS51475 Proteasome alpha-type subunit profile. 1 212 54.054
4 g11495.t3 SUPERFAMILY SSF56235 N-terminal nucleophile aminohydrolases (Ntn hydrolases) 1 202 0.000

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0051603 proteolysis involved in cellular protein catabolic process BP
GO:0005839 proteasome core complex CC

KEGG

Orthology

This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values