General information for g11548.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Open rectifier potassium channel protein 1.
Parent gene
- The parent gene g11548 is located on chr_1: 16971892..16978753 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11548 | g11548.t1 | isoform | g11548.t1 | 16971892 | 16978753 |
| chr_1 | g11548 | g11548.t1 | exon | g11548.t1.exon1 | 16971892 | 16972917 |
| chr_1 | g11548 | g11548.t1 | cds | g11548.t1.CDS1 | 16971892 | 16972917 |
| chr_1 | g11548 | g11548.t1 | exon | g11548.t1.exon2 | 16973150 | 16973668 |
| chr_1 | g11548 | g11548.t1 | cds | g11548.t1.CDS2 | 16973150 | 16973668 |
| chr_1 | g11548 | g11548.t1 | exon | g11548.t1.exon3 | 16973870 | 16974017 |
| chr_1 | g11548 | g11548.t1 | cds | g11548.t1.CDS3 | 16973870 | 16974017 |
| chr_1 | g11548 | g11548.t1 | exon | g11548.t1.exon4 | 16974125 | 16974164 |
| chr_1 | g11548 | g11548.t1 | cds | g11548.t1.CDS4 | 16974125 | 16974164 |
| chr_1 | g11548 | g11548.t1 | exon | g11548.t1.exon5 | 16974236 | 16974337 |
| chr_1 | g11548 | g11548.t1 | cds | g11548.t1.CDS5 | 16974236 | 16974337 |
| chr_1 | g11548 | g11548.t1 | exon | g11548.t1.exon6 | 16974419 | 16974632 |
| chr_1 | g11548 | g11548.t1 | cds | g11548.t1.CDS6 | 16974419 | 16974632 |
| chr_1 | g11548 | g11548.t1 | exon | g11548.t1.exon7 | 16974720 | 16974775 |
| chr_1 | g11548 | g11548.t1 | cds | g11548.t1.CDS7 | 16974720 | 16974775 |
| chr_1 | g11548 | g11548.t1 | exon | g11548.t1.exon8 | 16974876 | 16974941 |
| chr_1 | g11548 | g11548.t1 | cds | g11548.t1.CDS8 | 16974876 | 16974941 |
| chr_1 | g11548 | g11548.t1 | exon | g11548.t1.exon9 | 16975039 | 16975155 |
| chr_1 | g11548 | g11548.t1 | cds | g11548.t1.CDS9 | 16975039 | 16975155 |
| chr_1 | g11548 | g11548.t1 | exon | g11548.t1.exon10 | 16975220 | 16975279 |
| chr_1 | g11548 | g11548.t1 | cds | g11548.t1.CDS10 | 16975220 | 16975279 |
| chr_1 | g11548 | g11548.t1 | exon | g11548.t1.exon11 | 16978612 | 16978753 |
| chr_1 | g11548 | g11548.t1 | cds | g11548.t1.CDS11 | 16978612 | 16978753 |
| chr_1 | g11548 | g11548.t1 | TSS | g11548.t1 | NA | NA |
| chr_1 | g11548 | g11548.t1 | TTS | g11548.t1 | NA | NA |
Sequences
>g11548.t1 Gene=g11548 Length=2490
ATGAGTCCAAAACAATGGCTCTCGCTATTGACATTTTACATTTTATATCTGATTTTTGGT
GCCAGTGTTTTTTACCACATGGAACATAAATTGGAAACCCAACGACGGATTGCAGCAAAT
AGTGAACGCATTGAAATTAATGCTCTCTTGAAAAAATATCTGATAAATAACACCGAAATT
CAGGAAGAAATTTTGGACGAAGTGTCTGAGTATTGTGGAAAACCAGTTACACATCCATCT
AAAGATGAATATATTGCTCCTTACACTTGGAGCTTTTACCATGCGTTTTTCTTCTCATTC
ACCGTCTGCAGCACAGTTGGCTACGGAAACATTTACCCAACTAATTCAGCGGGCCGCTTG
TTTTTAATATTTTATGGACTCGTTGGATTACCGGTTCATGCAATTCTGTTCGCATATATG
GGTAATTTTTGGGGCAATACTTTTATCAACATGTATAAAAGATATAAAGAATATAAGATG
TCCATGGATAGTAATTGGGTACCAAGAAAACTGAATCTTATTGGTCGCATCTTTCTTTAC
CTTATACCCGGTATTGCTATGTTTATATTTGCACCAGCCATGATTTTCTCATATTTTGAA
GAATGGGACTACTTGGTGTCAGTATATTATGCTTTCGTCACCTTGACCACTATAGGACTT
GGAGATTTTGTAGCAACATTTCAACGTCATCAAGAAAAAACCTTTGGAACTTTATTCATC
TTTTATCAGCTCTTCATTCTTTGCTGGTTTATTGCAGGAGTAAGTTACATTGCAATGATT
ATAGGATTTCTTATCAAAGGCTTAAGGAGTAAAAGAATTAAGAGAATTGAACACAATCTA
GCTATAAATATCAAAGAAACTCAAAGAAAAATTTGGAATGGTGTACAAAAAGACGTAGGC
TATATAAGAAAAATTCTCAATGAAGTTTACTTTTCAAAATTCAAGCCAGTTTATAAAGAT
CCTGATGAGACAAAGAAAAATTTTCGTATCCCTCGCTCTCAGTCATGTCCACATTTATTT
ATGGATAACGACGATGAGAATGAGGAAGAAGAAGAGGAAAGAAACATAAAATACAGACGA
GAACGTGCCTTTTCTGAATGCCCAAAATTAAGACAAAAACGGCAACAAAGTTTTAGTGCA
ATGACACTACATCGACCACAATCCGATACCGATTTGAGCCAAATAGATCGTACAAAGACA
TTTGATGCACAGCGTGCTGCACTGGAGCCAGGCGAATTGCTTGCTAAAGTGACAATTGCA
TTGGGCGGATATCGTGTCGATGTAGCCGATGAGAATGATGACGAGAGTGAACTGGGCGTA
CATGGTTTTAGTGATTCAGAAATTTTAGCAAGCGAGCAAAATTACTCGGACTGGTCAATT
GAAACATCGGAAAAAAGTTGCTATATTGGACGTAATAGACGTGCCTTATCAGAAGTACGC
ATTCCAATTGAAGAATCAATAAAGACGTCGAACGAATGGACATGGTCCGGAGCAAATACA
CAAATAAGTGATATAGAAAAGATACGCGCACGAATGTCGAAACCGAAAAGAAATCTCTAC
CGAGCGTCCTTTCGAAAAAAATTACGATACGATTCTGATGTTGTTGATGATTTCCCTCGA
GAATCGCCTCACACGACAAATGGAACTGCGACAAATAAATCAATGCTACATAGATTAAAT
CCCTTCAAGAGGAAAATTCCTGAGATGATGAAGCGACATTCTTTGGCACCCGGGCAAGAG
CTGCATCCACAAAGGTACATTGATCGAAGGGAGTCAATTAATAGCTTGTCGAAGAAAAAT
TATCTGAGTCATGCAAGGGCGAGCATTTTCTCAATGCCATGTTATGAAGAAGAACAGGAT
TTGTTAGAAACGACAAGCGTAGCTGATTTAATTAGAGCCATTGAAATGTTTCACGTTGAT
AGCAATGCAGCAACCTCAACTGATTCTCTTACAAAGCGACGTAAAATGGGAACTGATCAC
TTATCCCATAAGTCTTCTTTATTAACACTTTTTTTGAATAAAAATCATGATTCTAGTCAC
ACAATACATAGCACACCTACTGCAGAAAATCCATCACAAATCATTAAAAAACAGAGAGGC
AGATTATATAGCTGCGTGTTAGAAAATCTTTCTTCATCCGAACATTATCACAATAGAGGC
AAAATTTCAAGCGATGCATTAGTTCGGAAGCAATCCATCTCTGCTTCACACCCGCCCCCA
CCACCGTATACTGTGAAGACTTCACAAAATGATTCATTAAAATCAACAATAAAACGTCGT
TTCAGCGTGAGACCTTCTAATCTTGATAAAGCACCTGGCCAGTTTCACAAAGCTCAAAAT
TTACCTGTCATTCCCGGATCTACTCTTGCACAGCAGCAGCAACATCAACAAAATCAAATT
TCAAATTCTAACCCATCTCCGTTGTCATTTGCAAGAAAATTGTCATTTCGAACAATTCCA
TCGTCACTGTCAAAAGCAAATGAACATTAG
>g11548.t1 Gene=g11548 Length=829
MSPKQWLSLLTFYILYLIFGASVFYHMEHKLETQRRIAANSERIEINALLKKYLINNTEI
QEEILDEVSEYCGKPVTHPSKDEYIAPYTWSFYHAFFFSFTVCSTVGYGNIYPTNSAGRL
FLIFYGLVGLPVHAILFAYMGNFWGNTFINMYKRYKEYKMSMDSNWVPRKLNLIGRIFLY
LIPGIAMFIFAPAMIFSYFEEWDYLVSVYYAFVTLTTIGLGDFVATFQRHQEKTFGTLFI
FYQLFILCWFIAGVSYIAMIIGFLIKGLRSKRIKRIEHNLAINIKETQRKIWNGVQKDVG
YIRKILNEVYFSKFKPVYKDPDETKKNFRIPRSQSCPHLFMDNDDENEEEEEERNIKYRR
ERAFSECPKLRQKRQQSFSAMTLHRPQSDTDLSQIDRTKTFDAQRAALEPGELLAKVTIA
LGGYRVDVADENDDESELGVHGFSDSEILASEQNYSDWSIETSEKSCYIGRNRRALSEVR
IPIEESIKTSNEWTWSGANTQISDIEKIRARMSKPKRNLYRASFRKKLRYDSDVVDDFPR
ESPHTTNGTATNKSMLHRLNPFKRKIPEMMKRHSLAPGQELHPQRYIDRRESINSLSKKN
YLSHARASIFSMPCYEEEQDLLETTSVADLIRAIEMFHVDSNAATSTDSLTKRRKMGTDH
LSHKSSLLTLFLNKNHDSSHTIHSTPTAENPSQIIKKQRGRLYSCVLENLSSSEHYHNRG
KISSDALVRKQSISASHPPPPPYTVKTSQNDSLKSTIKRRFSVRPSNLDKAPGQFHKAQN
LPVIPGSTLAQQQQHQQNQISNSNPSPLSFARKLSFRTIPSSLSKANEH
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g11548.t1 | Coils | Coil | Coil | 341 | 361 | - |
| 9 | g11548.t1 | Gene3D | G3DSA:1.10.287.70 | - | 4 | 282 | 2.8E-60 |
| 30 | g11548.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 733 | 753 | - |
| 3 | g11548.t1 | PANTHER | PTHR11003:SF304 | OPEN RECTIFIER POTASSIUM CHANNEL PROTEIN 1 | 5 | 293 | 6.0E-61 |
| 4 | g11548.t1 | PANTHER | PTHR11003 | POTASSIUM CHANNEL, SUBFAMILY K | 5 | 293 | 6.0E-61 |
| 6 | g11548.t1 | PRINTS | PR01333 | Two pore domain K+ channel signature | 101 | 129 | 3.5E-14 |
| 5 | g11548.t1 | PRINTS | PR01333 | Two pore domain K+ channel signature | 216 | 225 | 3.5E-14 |
| 1 | g11548.t1 | Pfam | PF07885 | Ion channel | 88 | 143 | 1.2E-15 |
| 2 | g11548.t1 | Pfam | PF07885 | Ion channel | 186 | 266 | 3.8E-10 |
| 15 | g11548.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1 | 5 | - |
| 21 | g11548.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 6 | 27 | - |
| 12 | g11548.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 28 | 89 | - |
| 20 | g11548.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 90 | 111 | - |
| 14 | g11548.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 112 | 122 | - |
| 22 | g11548.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 123 | 152 | - |
| 11 | g11548.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 153 | 172 | - |
| 19 | g11548.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 173 | 196 | - |
| 17 | g11548.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 197 | 207 | - |
| 18 | g11548.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 208 | 227 | - |
| 13 | g11548.t1 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 228 | 238 | - |
| 23 | g11548.t1 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 239 | 265 | - |
| 16 | g11548.t1 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 266 | 829 | - |
| 8 | g11548.t1 | SUPERFAMILY | SSF81324 | Voltage-gated potassium channels | 5 | 173 | 2.22E-26 |
| 7 | g11548.t1 | SUPERFAMILY | SSF81324 | Voltage-gated potassium channels | 169 | 282 | 7.06E-18 |
| 29 | g11548.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 5 | 27 | - |
| 27 | g11548.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 90 | 112 | - |
| 25 | g11548.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 122 | 144 | - |
| 24 | g11548.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 173 | 195 | - |
| 26 | g11548.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 205 | 227 | - |
| 28 | g11548.t1 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 239 | 261 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016020 | membrane | CC |
| GO:0005267 | potassium channel activity | MF |
| GO:0071805 | potassium ion transmembrane transport | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed