General information for g11566.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Interference hedgehog.
Parent gene
- The parent gene g11566 is located on chr_1: 17171551..17174532 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11566 | g11566.t2 | isoform | g11566.t2 | 17170939 | 17174532 |
| chr_1 | g11566 | g11566.t2 | exon | g11566.t2.exon1 | 17170939 | 17171211 |
| chr_1 | g11566 | g11566.t2 | cds | g11566.t2.CDS1 | 17170939 | 17171211 |
| chr_1 | g11566 | g11566.t2 | exon | g11566.t2.exon2 | 17171283 | 17171551 |
| chr_1 | g11566 | g11566.t2 | cds | g11566.t2.CDS2 | 17171283 | 17171551 |
| chr_1 | g11566 | g11566.t2 | exon | g11566.t2.exon3 | 17171614 | 17172449 |
| chr_1 | g11566 | g11566.t2 | cds | g11566.t2.CDS3 | 17171614 | 17172449 |
| chr_1 | g11566 | g11566.t2 | exon | g11566.t2.exon4 | 17172583 | 17173227 |
| chr_1 | g11566 | g11566.t2 | cds | g11566.t2.CDS4 | 17172583 | 17173227 |
| chr_1 | g11566 | g11566.t2 | exon | g11566.t2.exon5 | 17173286 | 17173474 |
| chr_1 | g11566 | g11566.t2 | cds | g11566.t2.CDS5 | 17173286 | 17173474 |
| chr_1 | g11566 | g11566.t2 | exon | g11566.t2.exon6 | 17173543 | 17173685 |
| chr_1 | g11566 | g11566.t2 | cds | g11566.t2.CDS6 | 17173543 | 17173685 |
| chr_1 | g11566 | g11566.t2 | exon | g11566.t2.exon7 | 17174074 | 17174236 |
| chr_1 | g11566 | g11566.t2 | cds | g11566.t2.CDS7 | 17174074 | 17174236 |
| chr_1 | g11566 | g11566.t2 | exon | g11566.t2.exon8 | 17174318 | 17174532 |
| chr_1 | g11566 | g11566.t2 | cds | g11566.t2.CDS8 | 17174318 | 17174532 |
| chr_1 | g11566 | g11566.t2 | TTS | g11566.t2 | 17175488 | 17175488 |
| chr_1 | g11566 | g11566.t2 | TSS | g11566.t2 | NA | NA |
Sequences
>g11566.t2 Gene=g11566 Length=2733
ATGCAACATATTTATTTCAACCAAAAGTCATTTATGCTATTAATGCTGATATATTATTTA
ATATTATCGCAATGCCACGCATATAAACATGATTCAGAGACAAGCTTAGGAACATATATG
ACTGTTGCACCTGAATCAACGGACGCACCAGCGGGAGATGAGGTTCAACTACAATGTGAA
CTGAATCTTCCACCTGAGAAAGTTGAATTCCACTTTCGACCTCAAAATAGCACCATAAAT
GACCGTGATAGAATCATTGATATACAAAAAATGACATCCTACAATATTACAACAAAAGAT
AGACTTTCAAAACTCCATGTATATGTTAATCAGAAGACTGTGGGTGATTATCGATGTGTT
GCGTGGTTTGGCGCCTCCGCACATGCATCAACTTCTGCAAAACTAAGATTAGCTTCAATT
TCATTAGAAGACAGAGACACACGAAAGCCATTAATTTCACTAAAAATTGCACCGCGCAAC
AGCATCATTTTACGTTGTGGCAATGTAACTTCCTCTCCCGATCCTGTTTGGAGTTATTAT
AAAGATGATATTCTCTTGCCAACTTCCAATCAGGTGCAGAGTAAATATGGTGGTTATATT
CTTAAAAATCTCACAGACAAAGATTCGGGTATTTATAGTTGTTCAGCTATGAATACTGTA
GCCGGTACAGAAATTAAATTGCCGCAACGCTACTCAATCACTGTCACACCAACGTCAAGA
AGTGCACCTTCGTTTTTACTCGAACCATTGTCATCATTTGCCGTAAAGCCAGGAGAAAAC
GTGTTACTAGAATGCTCGGCTGTCTCGAATCCGGTTTTTAAAGCGACATGGAGTAGGCCT
GATAAAAATTTAAATTTAAATGATGATCGAATTAGTATAATGGGTTATGGACTGCAAATA
AATAATGTAAAGATGGAAGACGAAGGCACATATATTTGTAGGCTTGATAATGGCGAGAAT
TCAGTAAAAATACACACAATCAAACTCAACATTCTTCAGATGCCAGAAATTCAAGAGGGA
CCAAAGACATCGTTGACAAATGAGAGTGAATCACTCGAACTTCAATGCCACGCGACTGGC
TCGCCAACTCCCGATATCTATTGGATGATAAATGGCGAGAATGTTCAGTTTGATCCACTC
ATTAAACAAGAAGGAGCAAAACTGATAATCTCGTCGGTTGAAAAGCGCCATGCTGGAATC
GTTCAATGTTTTGCGCGAAATGAAGTTGGAGAAGTTAATGAAGGTGCACTTTTGCAAGTG
AATCCAAAACAAATCGACGGTGAAGGTAAACCCATACCGCTTGGAAGAATGCCTCATAAA
TCAAAATCAAGAAACAACAACAATCGTATGCACAATGGAAAACGCAAGAATAAAGGACCA
AATCTACCAAATATTGCTAAGCCAAATATCACACGATTAAATGATGAAGCAGTGATGGTA
AAATGGTCGGTCATGCAACAGACATCGATGGAAGGATCGTTGCCAATACAATTCTTCAAA
GTGCAATATATTCTCATACCTCAAGAAGTTCAGCAGCGTAAAAATGAAGATTGGATTACA
TTGTCTGAAGATATTCCACCGCACTTGCGTTCATATGAAATTCACAATCTTAAACCGGAT
AATCATTACAAATTTCGCATTTCGGCGGTTTATTCAAATAACGATAATAAGCAAAGTCCA
ATAAGACGATTTCATCTTAAGCGTATTAAACAGAATAGCAAGAACAATTTGCCCATTCCA
ACTGAAATACACATCGAATCAATTTCTGAGACAGAGGTTAAAGTCAAGTGGTCAATACCC
GAAGCAATACATCATCAGCATTATAGTTTTGGTGGATTTTATATTAGTTATCGACCTACA
ACATCGGCTGATGATTATTTAGTTGTTTCTTGCGAAGGCTCACACAAACGACATCACAAT
ATTAAATTTTTAGAACCAGGCACAAATTATGAATTTAAAATACAAAGTTTCTCCGCAATG
GCCGCTTCTGAGTTTAGTTCGATTGTTACAGGCAGAACTCTTAGAACTACTGTGCCACCA
TATACCACTCCACCAACAATTAAGTCCGTCAAGACTGATATAAAGAGTCAGAATCCAACA
TCATTCTTACCTTTAATAATTATTGGCGGATGTGCTCTTCTCGTCTTAATCTTGATATTA
GTTTTTATTGCCTTGAAAAAGCGTCGAGATATAGTCAATAATCAACACGAAGAACAAGAG
AGCAAATCAAATCCGAATCATATACAAGTTGATTCAGTCACTAATGGCAGACGATCACCA
ATTTTGCGCAACAATAGGCATCTGAATGGCATTTTACGCATCAATATTACACCGAATCCA
CTGACAGATGAAAAAAATGATGTCAATGCACTAGGAATTCCTATTATTCCACCGACAACA
CATCAACAGCTGCCGCCACTTGGCCCACATCGCAAAACACTTGAGAGAAACATCCGAAAT
AATCATCACAATCAAATGCCAAATGGCATTATTGAATCCACTAAGACAATGATTGATGGT
GACCTTGGAGTTTCCGCACGATCAGCATCCATAAGACGACAACCTTTTATTAATGGATCA
AATAATTCAATTAACAATAGCAGTCCTCGAATTATAAGAAGTCATCAGCGTGTTCAAAGA
TCACCTATGCTCACACGAACGGCATCAAAACGACGCGGCGATATTGAGCAATCCACAGCA
AGTCTAAATAGTGTCAATAGTATTGAAGTGTGA
>g11566.t2 Gene=g11566 Length=910
MQHIYFNQKSFMLLMLIYYLILSQCHAYKHDSETSLGTYMTVAPESTDAPAGDEVQLQCE
LNLPPEKVEFHFRPQNSTINDRDRIIDIQKMTSYNITTKDRLSKLHVYVNQKTVGDYRCV
AWFGASAHASTSAKLRLASISLEDRDTRKPLISLKIAPRNSIILRCGNVTSSPDPVWSYY
KDDILLPTSNQVQSKYGGYILKNLTDKDSGIYSCSAMNTVAGTEIKLPQRYSITVTPTSR
SAPSFLLEPLSSFAVKPGENVLLECSAVSNPVFKATWSRPDKNLNLNDDRISIMGYGLQI
NNVKMEDEGTYICRLDNGENSVKIHTIKLNILQMPEIQEGPKTSLTNESESLELQCHATG
SPTPDIYWMINGENVQFDPLIKQEGAKLIISSVEKRHAGIVQCFARNEVGEVNEGALLQV
NPKQIDGEGKPIPLGRMPHKSKSRNNNNRMHNGKRKNKGPNLPNIAKPNITRLNDEAVMV
KWSVMQQTSMEGSLPIQFFKVQYILIPQEVQQRKNEDWITLSEDIPPHLRSYEIHNLKPD
NHYKFRISAVYSNNDNKQSPIRRFHLKRIKQNSKNNLPIPTEIHIESISETEVKVKWSIP
EAIHHQHYSFGGFYISYRPTTSADDYLVVSCEGSHKRHHNIKFLEPGTNYEFKIQSFSAM
AASEFSSIVTGRTLRTTVPPYTTPPTIKSVKTDIKSQNPTSFLPLIIIGGCALLVLILIL
VFIALKKRRDIVNNQHEEQESKSNPNHIQVDSVTNGRRSPILRNNRHLNGILRINITPNP
LTDEKNDVNALGIPIIPPTTHQQLPPLGPHRKTLERNIRNNHHNQMPNGIIESTKTMIDG
DLGVSARSASIRRQPFINGSNNSINNSSPRIIRSHQRVQRSPMLTRTASKRRGDIEQSTA
SLNSVNSIEV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 29 | g11566.t2 | CDD | cd00096 | Ig | 162 | 224 | 1.28785E-6 |
| 28 | g11566.t2 | CDD | cd00096 | Ig | 261 | 322 | 4.90487E-10 |
| 27 | g11566.t2 | CDD | cd00096 | Ig | 352 | 413 | 6.96244E-13 |
| 31 | g11566.t2 | CDD | cd00063 | FN3 | 467 | 564 | 9.7018E-7 |
| 30 | g11566.t2 | CDD | cd00063 | FN3 | 580 | 673 | 8.16764E-12 |
| 16 | g11566.t2 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 39 | 138 | 8.8E-6 |
| 19 | g11566.t2 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 152 | 237 | 2.4E-9 |
| 15 | g11566.t2 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 244 | 335 | 1.7E-17 |
| 17 | g11566.t2 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 336 | 421 | 1.8E-16 |
| 18 | g11566.t2 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 465 | 571 | 1.8E-13 |
| 14 | g11566.t2 | Gene3D | G3DSA:2.60.40.10 | Immunoglobulins | 577 | 676 | 7.8E-18 |
| 44 | g11566.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 426 | 463 | - |
| 46 | g11566.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 442 | 456 | - |
| 47 | g11566.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 736 | 762 | - |
| 45 | g11566.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 745 | 762 | - |
| 43 | g11566.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 880 | 910 | - |
| 42 | g11566.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 894 | 910 | - |
| 6 | g11566.t2 | PANTHER | PTHR44170:SF23 | BROTHER OF IHOG, ISOFORM G-RELATED | 25 | 447 | 1.1E-192 |
| 8 | g11566.t2 | PANTHER | PTHR44170 | PROTEIN SIDEKICK | 25 | 447 | 1.1E-192 |
| 5 | g11566.t2 | PANTHER | PTHR44170:SF23 | BROTHER OF IHOG, ISOFORM G-RELATED | 461 | 890 | 1.1E-192 |
| 7 | g11566.t2 | PANTHER | PTHR44170 | PROTEIN SIDEKICK | 461 | 890 | 1.1E-192 |
| 1 | g11566.t2 | Pfam | PF00047 | Immunoglobulin domain | 252 | 325 | 2.3E-11 |
| 2 | g11566.t2 | Pfam | PF13927 | Immunoglobulin domain | 335 | 407 | 4.7E-12 |
| 4 | g11566.t2 | Pfam | PF00041 | Fibronectin type III domain | 467 | 553 | 1.1E-6 |
| 3 | g11566.t2 | Pfam | PF00041 | Fibronectin type III domain | 580 | 664 | 3.4E-9 |
| 22 | g11566.t2 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 27 | - |
| 23 | g11566.t2 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 10 | - |
| 24 | g11566.t2 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 11 | 22 | - |
| 26 | g11566.t2 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 23 | 27 | - |
| 21 | g11566.t2 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 28 | 701 | - |
| 25 | g11566.t2 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 702 | 725 | - |
| 20 | g11566.t2 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 726 | 910 | - |
| 50 | g11566.t2 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 243 | 330 | 11.733 |
| 51 | g11566.t2 | ProSiteProfiles | PS50835 | Ig-like domain profile. | 335 | 419 | 11.969 |
| 48 | g11566.t2 | ProSiteProfiles | PS50853 | Fibronectin type-III domain profile. | 464 | 569 | 13.247 |
| 49 | g11566.t2 | ProSiteProfiles | PS50853 | Fibronectin type-III domain profile. | 579 | 676 | 17.515 |
| 36 | g11566.t2 | SMART | SM00409 | IG_3c | 44 | 138 | 4.8 |
| 35 | g11566.t2 | SMART | SM00409 | IG_3c | 151 | 236 | 4.0 |
| 39 | g11566.t2 | SMART | SM00408 | igc2_5 | 157 | 221 | 0.04 |
| 33 | g11566.t2 | SMART | SM00409 | IG_3c | 250 | 332 | 3.1E-9 |
| 40 | g11566.t2 | SMART | SM00408 | igc2_5 | 256 | 320 | 3.2E-8 |
| 34 | g11566.t2 | SMART | SM00409 | IG_3c | 341 | 421 | 1.2E-8 |
| 41 | g11566.t2 | SMART | SM00408 | igc2_5 | 347 | 410 | 3.9E-11 |
| 38 | g11566.t2 | SMART | SM00060 | FN3_2 | 462 | 558 | 0.0094 |
| 37 | g11566.t2 | SMART | SM00060 | FN3_2 | 577 | 663 | 2.3E-6 |
| 11 | g11566.t2 | SUPERFAMILY | SSF48726 | Immunoglobulin | 39 | 220 | 3.42E-10 |
| 12 | g11566.t2 | SUPERFAMILY | SSF48726 | Immunoglobulin | 243 | 339 | 7.62E-18 |
| 10 | g11566.t2 | SUPERFAMILY | SSF48726 | Immunoglobulin | 328 | 421 | 1.55E-16 |
| 9 | g11566.t2 | SUPERFAMILY | SSF49265 | Fibronectin type III | 462 | 675 | 2.05E-20 |
| 13 | g11566.t2 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 27 | - |
| 32 | g11566.t2 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 703 | 725 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K20245 (brother of ihog)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
