General information for g11637.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Fructose-bisphosphate aldolase.
Parent gene
- The parent gene g11637 is located on chr_1: 17536036..17544729 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11637 | g11637.t2 | TSS | g11637.t2 | 17529534 | 17529534 |
| chr_1 | g11637 | g11637.t2 | isoform | g11637.t2 | 17529563 | 17536099 |
| chr_1 | g11637 | g11637.t2 | exon | g11637.t2.exon1 | 17529563 | 17529697 |
| chr_1 | g11637 | g11637.t2 | cds | g11637.t2.CDS1 | 17529563 | 17529697 |
| chr_1 | g11637 | g11637.t2 | exon | g11637.t2.exon2 | 17529758 | 17530001 |
| chr_1 | g11637 | g11637.t2 | cds | g11637.t2.CDS2 | 17529758 | 17530001 |
| chr_1 | g11637 | g11637.t2 | exon | g11637.t2.exon3 | 17530300 | 17530722 |
| chr_1 | g11637 | g11637.t2 | cds | g11637.t2.CDS3 | 17530300 | 17530722 |
| chr_1 | g11637 | g11637.t2 | exon | g11637.t2.exon4 | 17530788 | 17530984 |
| chr_1 | g11637 | g11637.t2 | cds | g11637.t2.CDS4 | 17530788 | 17530984 |
| chr_1 | g11637 | g11637.t2 | exon | g11637.t2.exon5 | 17536004 | 17536099 |
| chr_1 | g11637 | g11637.t2 | cds | g11637.t2.CDS5 | 17536004 | 17536099 |
| chr_1 | g11637 | g11637.t2 | TTS | g11637.t2 | 17536972 | 17536972 |
Sequences
>g11637.t2 Gene=g11637 Length=1095
ATGACTACCTACTATAACAACTATCCAAAAGAATTGCAAGAAGAATTGAAGCGCATTGCA
AATGCAATTGTTGCTCCAGGAAAAGGTATCTTGGCTGCTGATGAATCAACTGCTACATGC
GGCAAGCGTTTTGCTGATATTGGATTAGAGAATAACGAAGAAAATCGTCGTGCATATCGT
GAATTACTTTTCACCACTGATGACGCTATTGCCACCAACATTTCAGGTGTCATTTTGTTC
CATGAGACCGTTTACCAAAAAGCTGCCTGTGGAACCTCATTCATTGATATCTTGAAGAAG
AAAGGTATCATTCCTGGTATCAAAGTCGACAGCGGTGTTGTTGATTTAATGGCAAGCGAA
GGAGAATGCACAACTCAAGGTCTCGATAACTTGGCACAACGTTGTGCTCAGTACAAGAAG
GATGGCTGTGACTTCGCCAAGTGGCGTTGTGTTTTGAAGATTGGCAAAAACACACCCAGC
TACCAAGCTATTTTGGAAAATGCCAATGTCTTGGCTCGCTATGCTTCAATCTGTCAATCA
CAAGGTATTGTTCCCATTGTTGAGCCTGAAATCTTGCCCGATGGTGACCACGATCTTGAG
CGTTGCCAGAAAGTCACTGAAGTTGTCTTGGCTGCTGTTTACAAAGCACTCAGCGATCAT
CATGTCTTCTTGGAAGGTACATTATTGAAACCAAACATGGTCACAGCTGGTATGCAATTT
AAGGGAACTAAACCAACACCTGAACAAATTGCTGAAGCTACTGTCACAGCTTTGCGCCGT
ACCGTTCCAGCTGCTGTTCCTGGTGTTACATTCTTGTCTGGTGGTCAATCAGAAGAAGAA
GCCTCAGTCAATTTGAACGCTATCAACAACCAACCAAAGAGACCATGGGCTTTGACATTC
TCATATGGTCGTGCTTTGCAAGCTTCAGTTTTGAGAGCATGGGGAGGTAAGAAGGAGAAT
GTAAAGGCTGGACAAGAGGAACTTCTTAAGCGTGCAAGGGCAAATGGCTTAGCTTCAGTT
GGCAAGTACACTGCTGGAAGCGTTGTAGGTGCAGGTGCTGATGCAACACTTTTCGTCGCT
AACCACGCTTATTAA
>g11637.t2 Gene=g11637 Length=364
MTTYYNNYPKELQEELKRIANAIVAPGKGILAADESTATCGKRFADIGLENNEENRRAYR
ELLFTTDDAIATNISGVILFHETVYQKAACGTSFIDILKKKGIIPGIKVDSGVVDLMASE
GECTTQGLDNLAQRCAQYKKDGCDFAKWRCVLKIGKNTPSYQAILENANVLARYASICQS
QGIVPIVEPEILPDGDHDLERCQKVTEVVLAAVYKALSDHHVFLEGTLLKPNMVTAGMQF
KGTKPTPEQIAEATVTALRRTVPAAVPGVTFLSGGQSEEEASVNLNAINNQPKRPWALTF
SYGRALQASVLRAWGGKKENVKAGQEELLKRARANGLASVGKYTAGSVVGAGADATLFVA
NHAY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g11637.t2 | CDD | cd00948 | FBP_aldolase_I_a | 14 | 343 | 0.0 |
| 6 | g11637.t2 | Gene3D | G3DSA:3.20.20.70 | Aldolase class I | 1 | 364 | 5.3E-181 |
| 2 | g11637.t2 | PANTHER | PTHR11627:SF1 | FRUCTOSE-BISPHOSPHATE ALDOLASE A | 2 | 364 | 5.7E-171 |
| 3 | g11637.t2 | PANTHER | PTHR11627 | FRUCTOSE-BISPHOSPHATE ALDOLASE | 2 | 364 | 5.7E-171 |
| 1 | g11637.t2 | Pfam | PF00274 | Fructose-bisphosphate aldolase class-I | 15 | 364 | 2.1E-180 |
| 5 | g11637.t2 | ProSitePatterns | PS00158 | Fructose-bisphosphate aldolase class-I active site. | 222 | 232 | - |
| 4 | g11637.t2 | SUPERFAMILY | SSF51569 | Aldolase | 4 | 364 | 4.61E-150 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004332 | fructose-bisphosphate aldolase activity | MF |
| GO:0006096 | glycolytic process | BP |
| GO:0003824 | catalytic activity | MF |
KEGG
Orthology
- This transcript has been annotated with K01623 (fructose-bisphosphate aldolase, class I)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
