General information for g11722.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Phosphatidylinositol 3-kinase catalytic subunit type 3.
Parent gene
- The parent gene g11722 is located on chr_1: 18076751..18077285 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11722 | g11722.t2 | isoform | g11722.t2 | 18074050 | 18075100 |
| chr_1 | g11722 | g11722.t2 | exon | g11722.t2.exon1 | 18074050 | 18074123 |
| chr_1 | g11722 | g11722.t2 | exon | g11722.t2.exon2 | 18074200 | 18074495 |
| chr_1 | g11722 | g11722.t2 | cds | g11722.t2.CDS1 | 18074460 | 18074495 |
| chr_1 | g11722 | g11722.t2 | exon | g11722.t2.exon3 | 18074554 | 18075100 |
| chr_1 | g11722 | g11722.t2 | cds | g11722.t2.CDS2 | 18074554 | 18075093 |
| chr_1 | g11722 | g11722.t2 | TSS | g11722.t2 | NA | NA |
| chr_1 | g11722 | g11722.t2 | TTS | g11722.t2 | NA | NA |
Sequences
>g11722.t2 Gene=g11722 Length=917
TAATTTGATGAAACAAAAATGCTTTATTGAAAATTTGGTCAAACTAGTGAAATTAGTTGC
AAAAGACTCTGGCAATAGAAAGAAGAAGACAGAAAAATTTCAACAATTGTTGTGTGATTC
AGATGAATTTAAAATTAATTTCACAAGCTTTGAACCATTACCGCTTCCACTTAATCCAGA
AATATTTATAAAAGGCATCGTAACATCAAAAGTCTCACTTTTCAAATCAGCCTTAATGCC
AGCAAAATTAACATTCCTTACGACTAATGATACAGAATATGTTGCAATTTTTAAAAATGG
CGATGATTTACGTCAGGATCAACTCATTTTACAAATGATTACTCTCATGGATAAGTTACT
AAGAAAAGAAAATTTAGATTTAAAGCTTACTCCATATCGGGTATTAGCATTATCATCTAA
ACATGGCTTTATGCAATATATTGAATCTATAACAGTTGCGGAGGCACTCAAAACAGAAGG
AACAATATTGAATTTTTTTAAAAAGCATAATCCTTGTGATACATCCTTGTATGGCATTCA
ATCTGAAGTGTCGGTGATAGACATTTGGATAATTTACTTTTAACTAAAAATGGAAATCTA
TTTCATATAGATTTTGGATATATTTTAGGACGAGATCCGAAACCTCTTCCTCCACCTATG
AAATTAAGCAAGGAGATGGTCGATGCTATGGGAGGAATAAATTCTGATCATTATCATGAG
TTTAGGAAACAATGTTATACAGCTTTTCTTCATCTTCGACGACATGCAAATGTCATGTTA
AATTTATTTTCACTTATGACAGATGCTTCAGTTCCCGATATTGCATTAGAACCTGATAAA
GCAATGTTTCTCTTTCTGCTGTTATGCCTGCATTAGTTGAACAAATACATAAATTAGCTC
AATATTGGAGAACATAA
>g11722.t2 Gene=g11722 Length=191
MKQKCFIENLVKLVKLVAKDSGNRKKKTEKFQQLLCDSDEFKINFTSFEPLPLPLNPEIF
IKGIVTSKVSLFKSALMPAKLTFLTTNDTEYVAIFKNGDDLRQDQLILQMITLMDKLLRK
ENLDLKLTPYRVLALSSKHGFMQYIESITVAEALKTEGTILNFFKKHNPCDTSLYGIQSE
VSVIDIWIIYF
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g11722.t2 | Gene3D | G3DSA:3.30.1010.10 | - | 1 | 146 | 5.0E-55 |
| 2 | g11722.t2 | PANTHER | PTHR10048 | PHOSPHATIDYLINOSITOL KINASE | 2 | 172 | 3.3E-49 |
| 3 | g11722.t2 | PANTHER | PTHR10048:SF7 | PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3 | 2 | 172 | 3.3E-49 |
| 1 | g11722.t2 | Pfam | PF00454 | Phosphatidylinositol 3- and 4-kinase | 91 | 155 | 2.3E-14 |
| 5 | g11722.t2 | ProSitePatterns | PS00915 | Phosphatidylinositol 3- and 4-kinases signature 1. | 95 | 109 | - |
| 7 | g11722.t2 | ProSiteProfiles | PS50290 | Phosphatidylinositol 3- and 4-kinases family profile. | 91 | 191 | 25.453 |
| 4 | g11722.t2 | SUPERFAMILY | SSF56112 | Protein kinase-like (PK-like) | 2 | 173 | 2.45E-31 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0016301 | kinase activity | MF |
| GO:0048015 | phosphatidylinositol-mediated signaling | BP |
| GO:0046854 | phosphatidylinositol phosphate biosynthetic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
