General information for g11722.t6
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Phosphatidylinositol 3-kinase catalytic subunit type 3.
Parent gene
- The parent gene g11722 is located on chr_1: 18076751..18077285 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11722 | g11722.t6 | isoform | g11722.t6 | 18075100 | 18076484 |
| chr_1 | g11722 | g11722.t6 | exon | g11722.t6.exon1 | 18075100 | 18075512 |
| chr_1 | g11722 | g11722.t6 | cds | g11722.t6.CDS1 | 18075100 | 18075512 |
| chr_1 | g11722 | g11722.t6 | exon | g11722.t6.exon2 | 18075572 | 18076124 |
| chr_1 | g11722 | g11722.t6 | cds | g11722.t6.CDS2 | 18075572 | 18076124 |
| chr_1 | g11722 | g11722.t6 | exon | g11722.t6.exon3 | 18076201 | 18076484 |
| chr_1 | g11722 | g11722.t6 | cds | g11722.t6.CDS3 | 18076201 | 18076326 |
| chr_1 | g11722 | g11722.t6 | TSS | g11722.t6 | 18077359 | 18077359 |
| chr_1 | g11722 | g11722.t6 | TTS | g11722.t6 | NA | NA |
Sequences
>g11722.t6 Gene=g11722 Length=1250
ATCAATTGCAATTTGCTTCTTATCAATTAAAAAATTTACTCTACTTTTGTTTATATAAAA
AAAAGAGATAATTTGTTTTTAAGTAAAAATGTAATTTTTAAATCAGTTGTGTTTCATACA
TATTTCATGTTTGTTTATAACAACATAATATCTCTGATATGTCTTTAAATAATTTTTTAA
AAAAAATTATTAAGTTATTAATTAAATATTTAAAAAAAATTTTACCACCTCAATATTTTT
ATACATCCTGCAAATCATCAAATTATCAAATTTATTTTATTGATGAAAACCTAGTTGAAA
AAAAACATCATCGATTGGCACGTTCAGCTCGTTCAGGTTTATCTGATCGCGATGCAAAGC
CAACCGCTCAAATTAGAGATCAACTACACTCACTTGTGCATAGATCACCAACATTTCAAT
TAAACAGTGAAGAACAGGATTTGATATGGAAATATAGATTTTATTTAAGCACTCAAAAGA
AGGCGCTTACAAAATTTCTTAAATGTATTAATTGGCAAACATCTGCAGAAGTAAGACAAG
CTCTTAATCTTCTGGACTTATGGGCACCAATGGATGTTGAAGATGCTCTTGAATTATTGA
GTCCGAATTTTCAACATCCAGCTGTTAGGCGATATGCGATAACACGTCTAAAGCAGTCAC
AGGATGATGATTTACTTCTCTATTTACTTCAGCTTGTACAAGCATTAAAATATGAAAATT
TTGATGATATTTTTGAATGGCGTCGACGTGTTATGAATGAAAAAGACATTTTAAAATCGA
TTGATGATAACAATTCCACTACTAACGATCAAAGTTCAATTTCTGATTCCATAATGGCTC
AATCTATGACATCTCAACAATTTTTAAATGAATCAGAAGAAATAATTGTACCACCTTTAA
ATCAACAATCTATCATGTCAAGTTCAATATTTTATGATCAACAAAATGATAATATAAGTG
ATCAACCGAGAATTGATGATTCTAATAATGATGTAACATCAGATATTTCAAATACTTTGA
TGAATTCAAAAAGTTCATATATTTGTGATTTAGCAACATTTTTAATTCAAAGAGCATGTA
AAAATCCAACACTCGCTAATTTTTTCTATTGGTATTTGTTGATAGAATGTGAAGATCATG
AAACTGTTAGAAAAAAAGACGAAAGAGTGCGAGAGATGTATGAAAATGTGCAAAAAATTT
TCCTTAAAACTCTGGAAATGGGTAATACAGATTTGAAAATCATTCATTCT
>g11722.t6 Gene=g11722 Length=364
MSLNNFLKKIIKLLIKYLKKILPPQYFYTSCKSSNYQIYFIDENLVEKKHHRLARSARSG
LSDRDAKPTAQIRDQLHSLVHRSPTFQLNSEEQDLIWKYRFYLSTQKKALTKFLKCINWQ
TSAEVRQALNLLDLWAPMDVEDALELLSPNFQHPAVRRYAITRLKQSQDDDLLLYLLQLV
QALKYENFDDIFEWRRRVMNEKDILKSIDDNNSTTNDQSSISDSIMAQSMTSQQFLNESE
EIIVPPLNQQSIMSSSIFYDQQNDNISDQPRIDDSNNDVTSDISNTLMNSKSSYICDLAT
FLIQRACKNPTLANFFYWYLLIECEDHETVRKKDERVREMYENVQKIFLKTLEMGNTDLK
IIHS
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g11722.t6 | Gene3D | G3DSA:1.25.40.70 | - | 68 | 258 | 0.000 |
| 7 | g11722.t6 | Gene3D | G3DSA:1.25.40.70 | - | 279 | 356 | 0.000 |
| 2 | g11722.t6 | PANTHER | PTHR10048 | PHOSPHATIDYLINOSITOL KINASE | 35 | 346 | 0.000 |
| 3 | g11722.t6 | PANTHER | PTHR10048:SF7 | PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3 | 35 | 346 | 0.000 |
| 1 | g11722.t6 | Pfam | PF00613 | Phosphoinositide 3-kinase family, accessory domain (PIK domain) | 65 | 342 | 0.000 |
| 8 | g11722.t6 | ProSiteProfiles | PS51545 | PIK helical domain profile. | 62 | 344 | 31.216 |
| 5 | g11722.t6 | SMART | SM00145 | pi3k_hr2_4 | 63 | 361 | 0.000 |
| 4 | g11722.t6 | SUPERFAMILY | SSF48371 | ARM repeat | 47 | 343 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0048015 | phosphatidylinositol-mediated signaling | BP |
| GO:0046854 | phosphatidylinositol phosphate biosynthetic process | BP |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed