General information for g11965.t2
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative Tether containing UBX domain for GLUT4.
Parent gene
- The parent gene g11965 is located on chr_1: 19953238..19954069 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11965 | g11965.t2 | TTS | g11965.t2 | 19952450 | 19952450 |
| chr_1 | g11965 | g11965.t2 | isoform | g11965.t2 | 19952489 | 19954069 |
| chr_1 | g11965 | g11965.t2 | exon | g11965.t2.exon1 | 19952489 | 19952799 |
| chr_1 | g11965 | g11965.t2 | cds | g11965.t2.CDS1 | 19952489 | 19952799 |
| chr_1 | g11965 | g11965.t2 | exon | g11965.t2.exon2 | 19952852 | 19954069 |
| chr_1 | g11965 | g11965.t2 | cds | g11965.t2.CDS2 | 19952852 | 19953794 |
| chr_1 | g11965 | g11965.t2 | TSS | g11965.t2 | 19954162 | 19954162 |
Sequences
>g11965.t2 Gene=g11965 Length=1529
ATGTCAAGTGTCACTGTTCTAACGCCGCATGGACGTCGACAGGTTGTGAAGATTGATCCA
AACAAAACTATTTTATGGGTAATTTTTTGAATATTTATTTTTTGCAAAGTGCCGAGTCAT
TACAAAATTGATGTTTATTGCAGATTCTTGAAGAAGTTTGTAGAAAATATAATGAATTTA
AACCTGAAAATTATGATTTGAAACATCATAATAAAACAGTAGATTTGAGTCAGTTCTTCA
GATTTTCTGGATTACCAAATAATTGTACATTAGAAATGGTTGAGGCAGATAAGAAGAGAA
TTGAACAAGATGTTGTGATTTGCCTTCAATTAGAAGACAATTCTCGTTTGAATGGAAGTT
TTCAGCCTTCAAGTAATCTTTATGATATAATCAATCAAATGGTACCCGAAATACTTCAAA
GTGATCAGACCAAAATTGTTGTTATATACATGAGAAATGAAATTTATGGTGAAAAATTAA
ATACAACTACATTAAAATCCTTAGGATTGTGCTCTGGTGGCCGTGCATTGTTTAGATTAA
TTAAATCTGATCCTGAAAGTTTAAAAAAGCAGGCAAATGTTAGTGCACCATTGCCTCAGA
AGCCTAAAGAGGAAGTACCAGAAAAACCAAGACCAAAAGGTGTCACAGCTGATTCACCAT
CTTTTCAGTTTCAAAGCACTAAACAAATAAAAGAACCTGAAAAAGAAGAAACTATTAAAC
AAAAAGAAGAGGAAAAAATGGAAATTGAAGAAGTTCCAATAAATAAAACAGAAGATCAAC
CATTTGTAGTAGTTGATGATACAAAGTTTGAATTGATTGAAGAAAAACTCAAAGCTGTAG
AACCAGAACCAGTGATTAATATTCTCGATGAACGCGGTACAATAATTTTTAACTTGGATT
CTATAAACACTTCATCATTAGATTTACCAGACAGCTTCTTTGAACTAACAGAAAGTGACG
TTCGAATGCTTTACAAAGATTTACGAAAGCAAGTTGAAGAGATTGAAAATCAACCACTCA
TGACAGAAGAGTTGAGAAAGCTTGAGGAGAATAAGAAGATATTAAATCAATTATCAACAT
ACAAAAATTGTGCTATTCGTATTCAATTTCCAGATAGGCATGTGATTCAGACGAAATTTT
CTACTGTAGATAATATTAACAATGTAATTCAATTCATAAGAGAATATCTTATTAATCCTA
ATATGGATTTTTATTTATATATAACACCTCCAAAAAATATTCTTGATAAAAATTTGACTC
TGGTTGAGTCTCATTGCGTTCCTTCAGCATTGTTACATTTTGGATGTGATGAGAATGTAA
AAGAATTTTTGAAACCAGAGTTTCTCAACAAATTATCTTCAGGATTTAGTGCATCGAGAG
TTCTTTTGAGTTCAAACAAGGATAATAATCAACCCAGTAGCAGTACTCCTACTTCTGTTT
CTTCATCTTCAGTTCCTAAAAATTTTATGGATTCAAAAGTCAGTTCAAAACCTTCAGGTG
CACCAAAATGGTTTAAATTAGGCAACTGA
>g11965.t2 Gene=g11965 Length=417
MVEADKKRIEQDVVICLQLEDNSRLNGSFQPSSNLYDIINQMVPEILQSDQTKIVVIYMR
NEIYGEKLNTTTLKSLGLCSGGRALFRLIKSDPESLKKQANVSAPLPQKPKEEVPEKPRP
KGVTADSPSFQFQSTKQIKEPEKEETIKQKEEEKMEIEEVPINKTEDQPFVVVDDTKFEL
IEEKLKAVEPEPVINILDERGTIIFNLDSINTSSLDLPDSFFELTESDVRMLYKDLRKQV
EEIENQPLMTEELRKLEENKKILNQLSTYKNCAIRIQFPDRHVIQTKFSTVDNINNVIQF
IREYLINPNMDFYLYITPPKNILDKNLTLVESHCVPSALLHFGCDENVKEFLKPEFLNKL
SSGFSASRVLLSSNKDNNQPSSSTPTSVSSSSVPKNFMDSKVSSKPSGAPKWFKLGN
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 7 | g11965.t2 | CDD | cd17075 | UBX1_UBXN9 | 12 | 88 | 1.29264E-18 |
| 6 | g11965.t2 | CDD | cd16118 | UBX2_UBXN9 | 272 | 344 | 1.99762E-26 |
| 5 | g11965.t2 | Coils | Coil | Coil | 226 | 246 | - |
| 4 | g11965.t2 | Gene3D | G3DSA:3.10.20.90 | - | 262 | 342 | 1.4E-9 |
| 9 | g11965.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 97 | 148 | - |
| 8 | g11965.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 375 | 403 | - |
| 10 | g11965.t2 | MobiDBLite | mobidb-lite | consensus disorder prediction | 375 | 417 | - |
| 2 | g11965.t2 | PANTHER | PTHR46467 | TETHER CONTAINING UBX DOMAIN FOR GLUT4 | 1 | 416 | 2.6E-74 |
| 1 | g11965.t2 | Pfam | PF00789 | UBX domain | 269 | 338 | 8.1E-6 |
| 11 | g11965.t2 | ProSiteProfiles | PS50033 | UBX domain profile. | 267 | 342 | 10.929 |
| 3 | g11965.t2 | SUPERFAMILY | SSF54236 | Ubiquitin-like | 244 | 342 | 2.33E-13 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005515 | protein binding | MF |
KEGG
Orthology
- This transcript has been annotated with K15627 (tether containing UBX domain for GLUT4)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
