General information for g11989.t13
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Putative 6-phosphogluconolactonase.
Parent gene
- The parent gene g11989 is located on chr_1: 20152301..20153547 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g11989 | g11989.t13 | TTS | g11989.t13 | 20151800 | 20151800 |
| chr_1 | g11989 | g11989.t13 | isoform | g11989.t13 | 20151867 | 20153547 |
| chr_1 | g11989 | g11989.t13 | exon | g11989.t13.exon1 | 20151867 | 20152347 |
| chr_1 | g11989 | g11989.t13 | cds | g11989.t13.CDS1 | 20151867 | 20152347 |
| chr_1 | g11989 | g11989.t13 | exon | g11989.t13.exon2 | 20152413 | 20152536 |
| chr_1 | g11989 | g11989.t13 | cds | g11989.t13.CDS2 | 20152413 | 20152536 |
| chr_1 | g11989 | g11989.t13 | exon | g11989.t13.exon3 | 20152607 | 20152783 |
| chr_1 | g11989 | g11989.t13 | cds | g11989.t13.CDS3 | 20152607 | 20152783 |
| chr_1 | g11989 | g11989.t13 | exon | g11989.t13.exon4 | 20153532 | 20153547 |
| chr_1 | g11989 | g11989.t13 | cds | g11989.t13.CDS4 | 20153532 | 20153547 |
| chr_1 | g11989 | g11989.t13 | TSS | g11989.t13 | NA | NA |
Sequences
>g11989.t13 Gene=g11989 Length=798
ATGTGTATAAGAGAAGTTTCCAACTTTGTGCATCTCATCATTAAATTTAATTTTTCTGTG
ATTATAAAAATGCCTGTGACACCTATAGTTTTGCACAATGAGGCATCTGTTCTTAATAAA
TTTCAAGAATTAATTGAAGAAATTGCCAATGAATCAATTAATGATCACGATCATTTTTAC
GTTGGTTTTTCAGGCGGTTCTTTAGGAAAATATTTGTGTCAAATATTACCTAAAATCAAA
ACTGATTGGAGCAAGTGGACAATTTTTTTCTGCGATGAGCGTTATGTTGATGAAAGTGAT
AACGAGTCAACATTTGGATTTTATAAAAACAATTTGATACCACTAGTTGCATTGACTGAG
CAGCAATTTATTTCAATCAATATTAACGATCCGATTGAAAAAGTTGCTGATGATTATGAG
AAAATAATAAGACAAAAATTTAATATGATTAAAGATGTTCCCTCATTTGATTGTTTACTT
CTTGGTGTTGGTCCAGATGGCCATACAGCTTCTTTATTTCCTGATCATCATATTTTGAAT
GAAAATGAACGTTTAATTACTTGGATCATTGATTCTCCTAAACCACCACCAAAAAGGATC
ACAATGACTTTTCCACTCATCAATAATGCAAAATATTCAATTTTTACTGTTCCCGGTAAA
GGCAAGGCTGAAATCATTAAAAAAATATTTGAAGATAAAATTGATTTCCCAGCTGCAAAA
GTTAATTCTAAAAAAGTCATTTGGCTGCTCGATCAAGATTCTGCATCCGAATGTTCAATT
AAATTTGATACAGTCTAA
>g11989.t13 Gene=g11989 Length=265
MCIREVSNFVHLIIKFNFSVIIKMPVTPIVLHNEASVLNKFQELIEEIANESINDHDHFY
VGFSGGSLGKYLCQILPKIKTDWSKWTIFFCDERYVDESDNESTFGFYKNNLIPLVALTE
QQFISININDPIEKVADDYEKIIRQKFNMIKDVPSFDCLLLGVGPDGHTASLFPDHHILN
ENERLITWIIDSPKPPPKRITMTFPLINNAKYSIFTVPGKGKAEIIKKIFEDKIDFPAAK
VNSKKVIWLLDQDSASECSIKFDTV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 6 | g11989.t13 | CDD | cd01400 | 6PGL | 43 | 250 | 0 |
| 4 | g11989.t13 | Gene3D | G3DSA:3.40.50.1360 | - | 19 | 258 | 0 |
| 2 | g11989.t13 | PANTHER | PTHR11054 | 6-PHOSPHOGLUCONOLACTONASE | 32 | 258 | 0 |
| 1 | g11989.t13 | Pfam | PF01182 | Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase | 34 | 248 | 0 |
| 3 | g11989.t13 | SUPERFAMILY | SSF100950 | NagB/RpiA/CoA transferase-like | 29 | 259 | 0 |
| 5 | g11989.t13 | TIGRFAM | TIGR01198 | pgl: 6-phosphogluconolactonase | 30 | 255 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0006098 | pentose-phosphate shunt | BP |
| GO:0017057 | 6-phosphogluconolactonase activity | MF |
| GO:0005975 | carbohydrate metabolic process | BP |
KEGG
Orthology
- This transcript has been annotated with K01057 (6-phosphogluconolactonase)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
