General information for g12081.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Myotubularin-related protein 14.
Parent gene
- The parent gene g12081 is located on chr_1: 20836411..20837991 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12081 | g12081.t1 | TTS | g12081.t1 | 20832589 | 20832589 |
| chr_1 | g12081 | g12081.t1 | isoform | g12081.t1 | 20833025 | 20836411 |
| chr_1 | g12081 | g12081.t1 | exon | g12081.t1.exon1 | 20833025 | 20833553 |
| chr_1 | g12081 | g12081.t1 | cds | g12081.t1.CDS1 | 20833025 | 20833553 |
| chr_1 | g12081 | g12081.t1 | exon | g12081.t1.exon2 | 20833617 | 20833931 |
| chr_1 | g12081 | g12081.t1 | cds | g12081.t1.CDS2 | 20833617 | 20833931 |
| chr_1 | g12081 | g12081.t1 | exon | g12081.t1.exon3 | 20834004 | 20834130 |
| chr_1 | g12081 | g12081.t1 | cds | g12081.t1.CDS3 | 20834004 | 20834130 |
| chr_1 | g12081 | g12081.t1 | exon | g12081.t1.exon4 | 20834184 | 20834281 |
| chr_1 | g12081 | g12081.t1 | cds | g12081.t1.CDS4 | 20834184 | 20834281 |
| chr_1 | g12081 | g12081.t1 | exon | g12081.t1.exon5 | 20834347 | 20834355 |
| chr_1 | g12081 | g12081.t1 | cds | g12081.t1.CDS5 | 20834347 | 20834355 |
| chr_1 | g12081 | g12081.t1 | exon | g12081.t1.exon6 | 20834547 | 20834769 |
| chr_1 | g12081 | g12081.t1 | cds | g12081.t1.CDS6 | 20834547 | 20834769 |
| chr_1 | g12081 | g12081.t1 | exon | g12081.t1.exon7 | 20834840 | 20835285 |
| chr_1 | g12081 | g12081.t1 | cds | g12081.t1.CDS7 | 20834840 | 20835285 |
| chr_1 | g12081 | g12081.t1 | exon | g12081.t1.exon8 | 20835436 | 20835677 |
| chr_1 | g12081 | g12081.t1 | cds | g12081.t1.CDS8 | 20835436 | 20835677 |
| chr_1 | g12081 | g12081.t1 | exon | g12081.t1.exon9 | 20836310 | 20836411 |
| chr_1 | g12081 | g12081.t1 | cds | g12081.t1.CDS9 | 20836310 | 20836411 |
| chr_1 | g12081 | g12081.t1 | TSS | g12081.t1 | 20836534 | 20836534 |
Sequences
>g12081.t1 Gene=g12081 Length=2091
ATGAATTCAGAAATTTTGATGCAAGATATTCAGACTTTGCTTGAGTTTTTTAGCAAAAAT
TGCTATCGAGCAAGCGACAGCAAAAACCTCGACTCATTTTTCGGAAATGATGTGTTGAAT
AAGTGCCACGTTTTAATGAAAAATGATTACAATGTTATAGAAATATCAAATTCTGTTGGT
GAACTTTCTTCACATTATCCATCAACTATTCTCATTCCCGAGTATGAACATCATAATCAA
TATAATCCCATTACCAATTCTCTCAATCTGCAACAGACCATATATGAGAGCACATACGAT
GCTAACAAACTTCGTGATCTTATCAATAAGGCTCGATTTGCGCGCTGTCGTGCACGATTC
CCTCTACCAATAATTTTATACAAAGGAAAATACATATGCAGAAGCGCTACGCTATCAGGT
GGAGCAGAAATTTATACTCGAAGCGGTTTAGATTATTTTTTCGCCAATGATAATTCGACT
GCAGTAAAAACGCCAAATTTAGATGAAGATGCATATGAAGCGCAAGAAACATCGATCAAT
GATGAAGAGGCACAAAGAAGAGGAACCGAAGATCGATGGCAATTATTTAATGTTGTTCGC
AGTTCAGACATTAAACTTCTCAAGACTTTCAACGTAGGAACAATTGTAGATTTCATGGTT
GAAAAAAAGAAAGTGAAATTTTTAGTTAATGTGACATCTTCAGAGAAGGTCGATAAAGAA
AAAAGATATTCAGATTTCCAAATCATCTCGTTGCCCTATCCAGGTTGCGAGTTTTTCAAA
GAATTTCGTGATAATAATTATTCTGGAGAGGGACTGGTATTTGACTGGTCACATAAGTCT
GTTGATGCTGAAATTTTGGTGCCTAAAGATGGTGTAACGCAGCAAATTAATATTGACTTT
GGTTCATATAAAAATTGGGATCTGGTTCAACTAACTCAAAACTACATGAAACTTTTATTA
AAAAATCTGCAAGATAATAGCTCTAGCATGTTGATTCATTGCATAAGTGGTGATTGGGAT
AGAACACCGCTTTTTGTCTCTCTTCTGCGTTTATCGCTTTGGGCTGATGGTTTAATTCAT
CAGTCATTGAGTGCTATCCAAATGCTTTATTTTACCATAGCCTACGATTGGATGCTATTT
GGTCATGATTTACAAGACCGACTTCAGAAGGGCGAAGAGATTTTCTTTTTCTGCTTCTAC
GTGCTAAAATATTTGATGGATGACGAATTCAGTATTGCTGGACAAAGATTTAGAAGCAGC
AAACAAAGTAGCAGTGGAAGTAGTTCAATTGGTGTGATACGAACAGATAGCGATGTTTTC
GATGGAATTCTTTTTGACGGTGATAGCAGAGGCTCGAGTAATTCTTTAAACTCAACATGT
AGCGCAAGAAGTCAGCAAGATCATAATTTAACGACATCGTCCAATGGCATGAGTATGCAT
TATGATGATAATAACGCTAATGGATGGGTGCAGAGTCAAGAAGGAAATAGCTTTAATTGC
TTAAATGCATCGACTGAAAACGCAACAAATATTCTAAATTTTTCACCACAACTACAGAGG
AGGACAAGTCCAATGTCAGTTCCAAAGATATCAAATCAAGAGAACAAGAGTAATCGTCAA
CGCAATGAATCATCATCAAGTGTTTCTGTGGGTAGTTGGCAACTCATAAGTGGAACAGGA
AGTCTTAGATCGCAAGATTCAAATATAGTTGTAATTAATGAATATCATCAGAATAATCAG
TGCAATAATAACAATAACAGCTCATATTCAAATCATGCACAATCTTCCACAACTCAGTCT
AATATGTGTTCAAACCAGCAAAATTTAAGCGGTAATGGCAGTGGAAGCAATAGTGCGACA
GTTAACAATTCAATACATGAATCTAGTACAATTGTTGATGATGATTGCTTTACTGCCAAT
GATTACTTTATGCGACGAGAGCGATTAAATTCAGTGCGAACGCTTTTTTATAATTGCTAT
AGTTCGACCATTGGATATAATTTTAGAAATGGTTCGAATGATGGGTCTTTTGGAACCCTT
TTAGGTAATTTTGCAGAGAGAGTTGGTCTCACACAAAGAACAACAGTGTAA
>g12081.t1 Gene=g12081 Length=696
MNSEILMQDIQTLLEFFSKNCYRASDSKNLDSFFGNDVLNKCHVLMKNDYNVIEISNSVG
ELSSHYPSTILIPEYEHHNQYNPITNSLNLQQTIYESTYDANKLRDLINKARFARCRARF
PLPIILYKGKYICRSATLSGGAEIYTRSGLDYFFANDNSTAVKTPNLDEDAYEAQETSIN
DEEAQRRGTEDRWQLFNVVRSSDIKLLKTFNVGTIVDFMVEKKKVKFLVNVTSSEKVDKE
KRYSDFQIISLPYPGCEFFKEFRDNNYSGEGLVFDWSHKSVDAEILVPKDGVTQQINIDF
GSYKNWDLVQLTQNYMKLLLKNLQDNSSSMLIHCISGDWDRTPLFVSLLRLSLWADGLIH
QSLSAIQMLYFTIAYDWMLFGHDLQDRLQKGEEIFFFCFYVLKYLMDDEFSIAGQRFRSS
KQSSSGSSSIGVIRTDSDVFDGILFDGDSRGSSNSLNSTCSARSQQDHNLTTSSNGMSMH
YDDNNANGWVQSQEGNSFNCLNASTENATNILNFSPQLQRRTSPMSVPKISNQENKSNRQ
RNESSSSVSVGSWQLISGTGSLRSQDSNIVVINEYHQNNQCNNNNNSSYSNHAQSSTTQS
NMCSNQQNLSGNGSGSNSATVNNSIHESSTIVDDDCFTANDYFMRRERLNSVRTLFYNCY
SSTIGYNFRNGSNDGSFGTLLGNFAERVGLTQRTTV
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 5 | g12081.t1 | Coils | Coil | Coil | 172 | 192 | - |
| 4 | g12081.t1 | MobiDBLite | mobidb-lite | consensus disorder prediction | 519 | 550 | - |
| 1 | g12081.t1 | PANTHER | PTHR13524 | MYOTUBULARIN-RELATED | 4 | 692 | 6.6E-199 |
| 2 | g12081.t1 | PANTHER | PTHR13524:SF2 | MYOTUBULARIN-RELATED PROTEIN 14 | 4 | 692 | 6.6E-199 |
| 3 | g12081.t1 | SUPERFAMILY | SSF52799 | (Phosphotyrosine protein) phosphatases II | 39 | 450 | 5.89E-48 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0004438 | phosphatidylinositol-3-phosphatase activity | MF |
KEGG
Orthology
- This transcript has been annotated with K18086 (myotubularin-related protein 14)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
