Gene loci information

Transcript annotation

  • This transcript has been annotated as Myotubularin-related protein 14.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g12081 g12081.t3 isoform g12081.t3 20832582 20836411
chr_1 g12081 g12081.t3 exon g12081.t3.exon1 20832582 20833553
chr_1 g12081 g12081.t3 TTS g12081.t3 20832589 20832589
chr_1 g12081 g12081.t3 cds g12081.t3.CDS1 20833025 20833553
chr_1 g12081 g12081.t3 exon g12081.t3.exon2 20833617 20833931
chr_1 g12081 g12081.t3 cds g12081.t3.CDS2 20833617 20833931
chr_1 g12081 g12081.t3 exon g12081.t3.exon3 20834004 20834130
chr_1 g12081 g12081.t3 cds g12081.t3.CDS3 20834004 20834130
chr_1 g12081 g12081.t3 exon g12081.t3.exon4 20834184 20834281
chr_1 g12081 g12081.t3 cds g12081.t3.CDS4 20834184 20834281
chr_1 g12081 g12081.t3 exon g12081.t3.exon5 20834547 20834769
chr_1 g12081 g12081.t3 cds g12081.t3.CDS5 20834547 20834769
chr_1 g12081 g12081.t3 exon g12081.t3.exon6 20834840 20835285
chr_1 g12081 g12081.t3 cds g12081.t3.CDS6 20834840 20835285
chr_1 g12081 g12081.t3 exon g12081.t3.exon7 20835436 20835677
chr_1 g12081 g12081.t3 cds g12081.t3.CDS7 20835436 20835677
chr_1 g12081 g12081.t3 exon g12081.t3.exon8 20836310 20836411
chr_1 g12081 g12081.t3 cds g12081.t3.CDS8 20836310 20836411
chr_1 g12081 g12081.t3 TSS g12081.t3 20836534 20836534

Sequences

>g12081.t3 Gene=g12081 Length=2525
ATGAATTCAGAAATTTTGATGCAAGATATTCAGACTTTGCTTGAGTTTTTTAGCAAAAAT
TGCTATCGAGCAAGCGACAGCAAAAACCTCGACTCATTTTTCGGAAATGATGTGTTGAAT
AAGTGCCACGTTTTAATGAAAAATGATTACAATGTTATAGAAATATCAAATTCTGTTGGT
GAACTTTCTTCACATTATCCATCAACTATTCTCATTCCCGAGTATGAACATCATAATCAA
TATAATCCCATTACCAATTCTCTCAATCTGCAACAGACCATATATGAGAGCACATACGAT
GCTAACAAACTTCGTGATCTTATCAATAAGGCTCGATTTGCGCGCTGTCGTGCACGATTC
CCTCTACCAATAATTTTATACAAAGGAAAATACATATGCAGAAGCGCTACGCTATCAGGT
GGAGCAGAAATTTATACTCGAAGCGGTTTAGATTATTTTTTCGCCAATGATAATTCGACT
GCAGTAAAAACGCCAAATTTAGATGAAGATGCATATGAAGCGCAAGAAACATCGATCAAT
GATGAAGAGGCACAAAGAAGAGGAACCGAAGATCGATGGCAATTATTTAATGTTGTTCGC
AGTTCAGACATTAAACTTCTCAAGACTTTCAACGTAGGAACAATTGTAGATTTCATGGTT
GAAAAAAAGAAAGTGAAATTTTTAGTTAATGTGACATCTTCAGAGAAGGTCGATAAAGAA
AAAAGATATTCAGATTTCCAAATCATCTCGTTGCCCTATCCAGGTTGCGAGTTTTTCAAA
GAATTTCGTGATAATAATTATTCTGGAGAGGGACTGGTATTTGACTGGTCACATAAGTCT
GTTGATGCTGAAATTTTGGTGCCTAAAGATGGTGTAACGCAGCAAATTAATATTGACTTT
GGTTCATATAAAAATTGGGATCTGGTTCAACTAACTCAAAACTACATGAAACTTTTATTA
AAAAATCTGCAAGATAATAGCTCTAGCATGTTGATTCATTGCATAAGTGGTGAAACACCG
CTTTTTGTCTCTCTTCTGCGTTTATCGCTTTGGGCTGATGGTTTAATTCATCAGTCATTG
AGTGCTATCCAAATGCTTTATTTTACCATAGCCTACGATTGGATGCTATTTGGTCATGAT
TTACAAGACCGACTTCAGAAGGGCGAAGAGATTTTCTTTTTCTGCTTCTACGTGCTAAAA
TATTTGATGGATGACGAATTCAGTATTGCTGGACAAAGATTTAGAAGCAGCAAACAAAGT
AGCAGTGGAAGTAGTTCAATTGGTGTGATACGAACAGATAGCGATGTTTTCGATGGAATT
CTTTTTGACGGTGATAGCAGAGGCTCGAGTAATTCTTTAAACTCAACATGTAGCGCAAGA
AGTCAGCAAGATCATAATTTAACGACATCGTCCAATGGCATGAGTATGCATTATGATGAT
AATAACGCTAATGGATGGGTGCAGAGTCAAGAAGGAAATAGCTTTAATTGCTTAAATGCA
TCGACTGAAAACGCAACAAATATTCTAAATTTTTCACCACAACTACAGAGGAGGACAAGT
CCAATGTCAGTTCCAAAGATATCAAATCAAGAGAACAAGAGTAATCGTCAACGCAATGAA
TCATCATCAAGTGTTTCTGTGGGTAGTTGGCAACTCATAAGTGGAACAGGAAGTCTTAGA
TCGCAAGATTCAAATATAGTTGTAATTAATGAATATCATCAGAATAATCAGTGCAATAAT
AACAATAACAGCTCATATTCAAATCATGCACAATCTTCCACAACTCAGTCTAATATGTGT
TCAAACCAGCAAAATTTAAGCGGTAATGGCAGTGGAAGCAATAGTGCGACAGTTAACAAT
TCAATACATGAATCTAGTACAATTGTTGATGATGATTGCTTTACTGCCAATGATTACTTT
ATGCGACGAGAGCGATTAAATTCAGTGCGAACGCTTTTTTATAATTGCTATAGTTCGACC
ATTGGATATAATTTTAGAAATGGTTCGAATGATGGGTCTTTTGGAACCCTTTTAGGTAAT
TTTGCAGAGAGAGTTGGTCTCACACAAAGAACAACAGTGTAAAAACAATTAAAAATTTTT
ATCACAAATGCAATGAGACGTCCAGTTACTAACTTTTTACATACTGCAAAAATGTTTAAG
ACTAACGATTTTAATTTCGTGAATTTTTATTTTTCTGTTAAACTTGTTATTTTTAATTAA
AATTTCTCCCTTTTAATTTCCGTTCTACTGTGTATTTTCTATATTTTCAGTAAATAATGT
TTCTTTCTCTGTTTAGACTTAATTTAAGTACCTAAATCAAAAAAAAAATATTTATTATGG
AACAATTATTTTTAGACAATTGAGGTTGAAATTTGAAAAATGTTATATTTGTCGCGAGAA
AAGAAAACCAACGTGTTCCATAACGATATTATAATATAAACGAAAATTTAAAACATATAT
TCTCCTGAAAAAAAAAATGAATAAAGAGAATAAGAAAGTATGATAAAATTTTGTTAAAAA
TAATA

>g12081.t3 Gene=g12081 Length=693
MNSEILMQDIQTLLEFFSKNCYRASDSKNLDSFFGNDVLNKCHVLMKNDYNVIEISNSVG
ELSSHYPSTILIPEYEHHNQYNPITNSLNLQQTIYESTYDANKLRDLINKARFARCRARF
PLPIILYKGKYICRSATLSGGAEIYTRSGLDYFFANDNSTAVKTPNLDEDAYEAQETSIN
DEEAQRRGTEDRWQLFNVVRSSDIKLLKTFNVGTIVDFMVEKKKVKFLVNVTSSEKVDKE
KRYSDFQIISLPYPGCEFFKEFRDNNYSGEGLVFDWSHKSVDAEILVPKDGVTQQINIDF
GSYKNWDLVQLTQNYMKLLLKNLQDNSSSMLIHCISGETPLFVSLLRLSLWADGLIHQSL
SAIQMLYFTIAYDWMLFGHDLQDRLQKGEEIFFFCFYVLKYLMDDEFSIAGQRFRSSKQS
SSGSSSIGVIRTDSDVFDGILFDGDSRGSSNSLNSTCSARSQQDHNLTTSSNGMSMHYDD
NNANGWVQSQEGNSFNCLNASTENATNILNFSPQLQRRTSPMSVPKISNQENKSNRQRNE
SSSSVSVGSWQLISGTGSLRSQDSNIVVINEYHQNNQCNNNNNSSYSNHAQSSTTQSNMC
SNQQNLSGNGSGSNSATVNNSIHESSTIVDDDCFTANDYFMRRERLNSVRTLFYNCYSST
IGYNFRNGSNDGSFGTLLGNFAERVGLTQRTTV

Protein features from InterProScan

Transcript Database ID Name Start End E.value
5 g12081.t3 Coils Coil Coil 172 192 -
4 g12081.t3 MobiDBLite mobidb-lite consensus disorder prediction 516 547 -
1 g12081.t3 PANTHER PTHR13524 MYOTUBULARIN-RELATED 4 689 1.2E-194
2 g12081.t3 PANTHER PTHR13524:SF2 MYOTUBULARIN-RELATED PROTEIN 14 4 689 1.2E-194
3 g12081.t3 SUPERFAMILY SSF52799 (Phosphotyrosine protein) phosphatases II 39 447 1.27E-44

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0004438 phosphatidylinositol-3-phosphatase activity MF

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values