General information for g12126.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Mitogen-activated protein kinase kinase kinase kinase 5.
Parent gene
- The parent gene g12126 is located on chr_1: 21184495..21185582 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12126 | g12126.t3 | isoform | g12126.t3 | 21181493 | 21183537 |
| chr_1 | g12126 | g12126.t3 | exon | g12126.t3.exon1 | 21181493 | 21182036 |
| chr_1 | g12126 | g12126.t3 | TTS | g12126.t3 | 21181500 | 21181500 |
| chr_1 | g12126 | g12126.t3 | cds | g12126.t3.CDS1 | 21181928 | 21182036 |
| chr_1 | g12126 | g12126.t3 | exon | g12126.t3.exon2 | 21182098 | 21182227 |
| chr_1 | g12126 | g12126.t3 | cds | g12126.t3.CDS2 | 21182098 | 21182227 |
| chr_1 | g12126 | g12126.t3 | exon | g12126.t3.exon3 | 21182285 | 21182414 |
| chr_1 | g12126 | g12126.t3 | cds | g12126.t3.CDS3 | 21182285 | 21182414 |
| chr_1 | g12126 | g12126.t3 | exon | g12126.t3.exon4 | 21182474 | 21182583 |
| chr_1 | g12126 | g12126.t3 | cds | g12126.t3.CDS4 | 21182474 | 21182583 |
| chr_1 | g12126 | g12126.t3 | exon | g12126.t3.exon5 | 21182661 | 21182846 |
| chr_1 | g12126 | g12126.t3 | cds | g12126.t3.CDS5 | 21182661 | 21182846 |
| chr_1 | g12126 | g12126.t3 | exon | g12126.t3.exon6 | 21182996 | 21183051 |
| chr_1 | g12126 | g12126.t3 | cds | g12126.t3.CDS6 | 21182996 | 21183051 |
| chr_1 | g12126 | g12126.t3 | exon | g12126.t3.exon7 | 21183117 | 21183537 |
| chr_1 | g12126 | g12126.t3 | cds | g12126.t3.CDS7 | 21183117 | 21183535 |
| chr_1 | g12126 | g12126.t3 | TSS | g12126.t3 | NA | NA |
Sequences
>g12126.t3 Gene=g12126 Length=1577
TGATGGGAGCGTGTTTCTCTAAAGTATTTAATGGTTGCCCTTTGCATATCAACTGTACAG
CTTCTTGGATTAATCCGGAAACTCGCGACCAGCATATTCTGATTGGTGCTGATGAGGGAA
TATTTACATTAAATATGAATGAGATACATGATGCAGTTATAGATCAAATATATCCACGAA
AAACAATATGGCTTTACGTAATTAAGGATGTATTGATGAGTTTGTCGGGCAAATCGAGTC
AATTATACCGCCACGATTTAGTTGCGCTGCATTCCAAACAAGCGACAAGTCGATTTACCC
TGCAGCTTCATATGCAAAAAATTCCAGAAAAGTTGGTTCCCAGAAAATTCGCTCTCACTA
CAAAAGTTCCCGATACAAAAGGATGCTTTCAGTGTTGCGTTATACGGAATCCTTATAATG
GTTATAAATATTTAGCGGGTAGACTTTCATCTGGTATATTTCTCATGCAGTGGTATGATC
CATTGAATAAGTTTATGTTATTGAAGCAATGTGAATGGCCTGCTCACAGTTTGCCTATGA
ATGATAATTCAGTATTTGAAATGATAATTTTGCCAGAATTGGAATATCCGCTAGTGTGTG
TGGGAGTCTCGAAATCATACGGAGGCAACGGCTTGAAACTTGAATTGTTCAATACAAATA
GTGCTGCTGGCTGGTTCAGTTTGTCATATGATGACGATGATTTTTCAGATATGGATAGAA
CTGCAACAATGATTCCAAAACGACTTCCAATGAAAATTATTAAAGTGCATCAGATGGAAA
AAGATATCATTGCAATCGTGCACGATAATGTTATAGAAATGGTAGATTTAAGTGGACAAC
CAAAAACTTCTAAGAAAATTGGTCTCTCAAAATCTGAGTTTGGCTTTAAAGTTGAAGGAA
TGGTGATAGTTCAAAATGATAGCATTTTGGCATTTCATTCTCACGGAATGCAAGGAAGAT
CTCTTAGAAATGGTGCCATTACGCAGGAAATTACAGATACGAGTAAAGTTTATCGATTAT
TAGGAAGTGAAAAGGTTGTGTGTCTCGAGAGTAGTCAAAAAAGAAGCAATAATAATGATG
GAAGTGCATCAGAAGAGTTTCACGATCTGTACACTTTGGCTGGTCATGAAGCTAGTTATT
AGAAGTTCTTTCATCTTAATTCCGAATAAAAGTCATTTTAATAAGCAGCAACAATTATAA
GAACAAAACAGATTTAAAAAAGTTTAGGACATATTAAACACCATTTAATTAAAGTAAAAC
GTAATGTAGGAAACGTACTACAAAGATGATATTACCTTAGAACATACATAGAGTGCAGGG
AGAGACCAATAATGTTCACAATTTGACGCAAATAAATATATTTAATTAAAATATGTCGTT
TTTGATGGAATATAAAAATTTGAAACATTCACACACAAAAAAAGAAGTTATAATAATTCA
TGTCACATGTTCAGAAGATCGTGAGAGAAAAACAAAAAGTTATGTTTTTTAAAATTCTTA
GATGTTTAATGCAAGTCATTATCTTTTAAATCCTGATAATAAAGATGAAAATTATTTTCT
AGTTTAAATTAAATTTC
>g12126.t3 Gene=g12126 Length=379
MGACFSKVFNGCPLHINCTASWINPETRDQHILIGADEGIFTLNMNEIHDAVIDQIYPRK
TIWLYVIKDVLMSLSGKSSQLYRHDLVALHSKQATSRFTLQLHMQKIPEKLVPRKFALTT
KVPDTKGCFQCCVIRNPYNGYKYLAGRLSSGIFLMQWYDPLNKFMLLKQCEWPAHSLPMN
DNSVFEMIILPELEYPLVCVGVSKSYGGNGLKLELFNTNSAAGWFSLSYDDDDFSDMDRT
ATMIPKRLPMKIIKVHQMEKDIIAIVHDNVIEMVDLSGQPKTSKKIGLSKSEFGFKVEGM
VIVQNDSILAFHSHGMQGRSLRNGAITQEITDTSKVYRLLGSEKVVCLESSQKRSNNNDG
SASEEFHDLYTLAGHEASY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 2 | g12126.t3 | PANTHER | PTHR48012:SF18 | HAPPYHOUR, ISOFORM A | 1 | 359 | 0.000 |
| 3 | g12126.t3 | PANTHER | PTHR48012 | STERILE20-LIKE KINASE, ISOFORM B-RELATED | 1 | 359 | 0.000 |
| 1 | g12126.t3 | Pfam | PF00780 | CNH domain | 24 | 339 | 0.000 |
| 5 | g12126.t3 | ProSiteProfiles | PS50219 | Citron homology (CNH) domain profile. | 13 | 345 | 19.332 |
| 4 | g12126.t3 | SMART | SM00036 | nik_2 | 18 | 352 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
