General information for g12126.t4
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Mitogen-activated protein kinase kinase kinase kinase 5.
Parent gene
- The parent gene g12126 is located on chr_1: 21184495..21185582 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12126 | g12126.t4 | isoform | g12126.t4 | 21181493 | 21183741 |
| chr_1 | g12126 | g12126.t4 | exon | g12126.t4.exon1 | 21181493 | 21182036 |
| chr_1 | g12126 | g12126.t4 | TTS | g12126.t4 | 21181500 | 21181500 |
| chr_1 | g12126 | g12126.t4 | cds | g12126.t4.CDS1 | 21181928 | 21182036 |
| chr_1 | g12126 | g12126.t4 | exon | g12126.t4.exon2 | 21182098 | 21182227 |
| chr_1 | g12126 | g12126.t4 | cds | g12126.t4.CDS2 | 21182098 | 21182227 |
| chr_1 | g12126 | g12126.t4 | exon | g12126.t4.exon3 | 21182285 | 21182414 |
| chr_1 | g12126 | g12126.t4 | cds | g12126.t4.CDS3 | 21182285 | 21182414 |
| chr_1 | g12126 | g12126.t4 | exon | g12126.t4.exon4 | 21182474 | 21182583 |
| chr_1 | g12126 | g12126.t4 | cds | g12126.t4.CDS4 | 21182474 | 21182583 |
| chr_1 | g12126 | g12126.t4 | exon | g12126.t4.exon5 | 21182661 | 21182846 |
| chr_1 | g12126 | g12126.t4 | cds | g12126.t4.CDS5 | 21182661 | 21182846 |
| chr_1 | g12126 | g12126.t4 | exon | g12126.t4.exon6 | 21182996 | 21183051 |
| chr_1 | g12126 | g12126.t4 | cds | g12126.t4.CDS6 | 21182996 | 21183051 |
| chr_1 | g12126 | g12126.t4 | exon | g12126.t4.exon7 | 21183117 | 21183541 |
| chr_1 | g12126 | g12126.t4 | cds | g12126.t4.CDS7 | 21183117 | 21183535 |
| chr_1 | g12126 | g12126.t4 | exon | g12126.t4.exon8 | 21183620 | 21183741 |
| chr_1 | g12126 | g12126.t4 | TSS | g12126.t4 | NA | NA |
Sequences
>g12126.t4 Gene=g12126 Length=1703
ATCAACCAGACATTCTAAATAATCTCAACAATACTCCTCCCGTGCCTCCAAAGAGAAAAC
ATCGTCATCGATCTCCACCATTCCATCATCCCATCACAAACGGTCTTCCTCCTACGCCAA
AGGTACTGATGGGAGCGTGTTTCTCTAAAGTATTTAATGGTTGCCCTTTGCATATCAACT
GTACAGCTTCTTGGATTAATCCGGAAACTCGCGACCAGCATATTCTGATTGGTGCTGATG
AGGGAATATTTACATTAAATATGAATGAGATACATGATGCAGTTATAGATCAAATATATC
CACGAAAAACAATATGGCTTTACGTAATTAAGGATGTATTGATGAGTTTGTCGGGCAAAT
CGAGTCAATTATACCGCCACGATTTAGTTGCGCTGCATTCCAAACAAGCGACAAGTCGAT
TTACCCTGCAGCTTCATATGCAAAAAATTCCAGAAAAGTTGGTTCCCAGAAAATTCGCTC
TCACTACAAAAGTTCCCGATACAAAAGGATGCTTTCAGTGTTGCGTTATACGGAATCCTT
ATAATGGTTATAAATATTTAGCGGGTAGACTTTCATCTGGTATATTTCTCATGCAGTGGT
ATGATCCATTGAATAAGTTTATGTTATTGAAGCAATGTGAATGGCCTGCTCACAGTTTGC
CTATGAATGATAATTCAGTATTTGAAATGATAATTTTGCCAGAATTGGAATATCCGCTAG
TGTGTGTGGGAGTCTCGAAATCATACGGAGGCAACGGCTTGAAACTTGAATTGTTCAATA
CAAATAGTGCTGCTGGCTGGTTCAGTTTGTCATATGATGACGATGATTTTTCAGATATGG
ATAGAACTGCAACAATGATTCCAAAACGACTTCCAATGAAAATTATTAAAGTGCATCAGA
TGGAAAAAGATATCATTGCAATCGTGCACGATAATGTTATAGAAATGGTAGATTTAAGTG
GACAACCAAAAACTTCTAAGAAAATTGGTCTCTCAAAATCTGAGTTTGGCTTTAAAGTTG
AAGGAATGGTGATAGTTCAAAATGATAGCATTTTGGCATTTCATTCTCACGGAATGCAAG
GAAGATCTCTTAGAAATGGTGCCATTACGCAGGAAATTACAGATACGAGTAAAGTTTATC
GATTATTAGGAAGTGAAAAGGTTGTGTGTCTCGAGAGTAGTCAAAAAAGAAGCAATAATA
ATGATGGAAGTGCATCAGAAGAGTTTCACGATCTGTACACTTTGGCTGGTCATGAAGCTA
GTTATTAGAAGTTCTTTCATCTTAATTCCGAATAAAAGTCATTTTAATAAGCAGCAACAA
TTATAAGAACAAAACAGATTTAAAAAAGTTTAGGACATATTAAACACCATTTAATTAAAG
TAAAACGTAATGTAGGAAACGTACTACAAAGATGATATTACCTTAGAACATACATAGAGT
GCAGGGAGAGACCAATAATGTTCACAATTTGACGCAAATAAATATATTTAATTAAAATAT
GTCGTTTTTGATGGAATATAAAAATTTGAAACATTCACACACAAAAAAAGAAGTTATAAT
AATTCATGTCACATGTTCAGAAGATCGTGAGAGAAAAACAAAAAGTTATGTTTTTTAAAA
TTCTTAGATGTTTAATGCAAGTCATTATCTTTTAAATCCTGATAATAAAGATGAAAATTA
TTTTCTAGTTTAAATTAAATTTC
>g12126.t4 Gene=g12126 Length=379
MGACFSKVFNGCPLHINCTASWINPETRDQHILIGADEGIFTLNMNEIHDAVIDQIYPRK
TIWLYVIKDVLMSLSGKSSQLYRHDLVALHSKQATSRFTLQLHMQKIPEKLVPRKFALTT
KVPDTKGCFQCCVIRNPYNGYKYLAGRLSSGIFLMQWYDPLNKFMLLKQCEWPAHSLPMN
DNSVFEMIILPELEYPLVCVGVSKSYGGNGLKLELFNTNSAAGWFSLSYDDDDFSDMDRT
ATMIPKRLPMKIIKVHQMEKDIIAIVHDNVIEMVDLSGQPKTSKKIGLSKSEFGFKVEGM
VIVQNDSILAFHSHGMQGRSLRNGAITQEITDTSKVYRLLGSEKVVCLESSQKRSNNNDG
SASEEFHDLYTLAGHEASY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 2 | g12126.t4 | PANTHER | PTHR48012:SF18 | HAPPYHOUR, ISOFORM A | 1 | 359 | 0.000 |
| 3 | g12126.t4 | PANTHER | PTHR48012 | STERILE20-LIKE KINASE, ISOFORM B-RELATED | 1 | 359 | 0.000 |
| 1 | g12126.t4 | Pfam | PF00780 | CNH domain | 24 | 339 | 0.000 |
| 5 | g12126.t4 | ProSiteProfiles | PS50219 | Citron homology (CNH) domain profile. | 13 | 345 | 19.332 |
| 4 | g12126.t4 | SMART | SM00036 | nik_2 | 18 | 352 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
