General information for g12126.t5
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Mitogen-activated protein kinase kinase kinase kinase 5.
Parent gene
- The parent gene g12126 is located on chr_1: 21184495..21185582 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12126 | g12126.t5 | isoform | g12126.t5 | 21181493 | 21183741 |
| chr_1 | g12126 | g12126.t5 | exon | g12126.t5.exon1 | 21181493 | 21182036 |
| chr_1 | g12126 | g12126.t5 | TTS | g12126.t5 | 21181500 | 21181500 |
| chr_1 | g12126 | g12126.t5 | cds | g12126.t5.CDS1 | 21181928 | 21182036 |
| chr_1 | g12126 | g12126.t5 | exon | g12126.t5.exon2 | 21182098 | 21182227 |
| chr_1 | g12126 | g12126.t5 | cds | g12126.t5.CDS2 | 21182098 | 21182227 |
| chr_1 | g12126 | g12126.t5 | exon | g12126.t5.exon3 | 21182285 | 21182414 |
| chr_1 | g12126 | g12126.t5 | cds | g12126.t5.CDS3 | 21182285 | 21182414 |
| chr_1 | g12126 | g12126.t5 | exon | g12126.t5.exon4 | 21182474 | 21182583 |
| chr_1 | g12126 | g12126.t5 | cds | g12126.t5.CDS4 | 21182474 | 21182583 |
| chr_1 | g12126 | g12126.t5 | exon | g12126.t5.exon5 | 21182664 | 21182846 |
| chr_1 | g12126 | g12126.t5 | cds | g12126.t5.CDS5 | 21182664 | 21182846 |
| chr_1 | g12126 | g12126.t5 | exon | g12126.t5.exon6 | 21182996 | 21183051 |
| chr_1 | g12126 | g12126.t5 | cds | g12126.t5.CDS6 | 21182996 | 21183051 |
| chr_1 | g12126 | g12126.t5 | exon | g12126.t5.exon7 | 21183117 | 21183541 |
| chr_1 | g12126 | g12126.t5 | cds | g12126.t5.CDS7 | 21183117 | 21183535 |
| chr_1 | g12126 | g12126.t5 | exon | g12126.t5.exon8 | 21183620 | 21183741 |
| chr_1 | g12126 | g12126.t5 | TSS | g12126.t5 | NA | NA |
Sequences
>g12126.t5 Gene=g12126 Length=1700
ATCAACCAGACATTCTAAATAATCTCAACAATACTCCTCCCGTGCCTCCAAAGAGAAAAC
ATCGTCATCGATCTCCACCATTCCATCATCCCATCACAAACGGTCTTCCTCCTACGCCAA
AGGTACTGATGGGAGCGTGTTTCTCTAAAGTATTTAATGGTTGCCCTTTGCATATCAACT
GTACAGCTTCTTGGATTAATCCGGAAACTCGCGACCAGCATATTCTGATTGGTGCTGATG
AGGGAATATTTACATTAAATATGAATGAGATACATGATGCAGTTATAGATCAAATATATC
CACGAAAAACAATATGGCTTTACGTAATTAAGGATGTATTGATGAGTTTGTCGGGCAAAT
CGAGTCAATTATACCGCCACGATTTAGTTGCGCTGCATTCCAAACAAGCGACAAGTCGAT
TTACCCTGCAGCTTCATATGCAAAAAATTCCAGAAAAGTTGGTTCCCAGAAAATTCGCTC
TCACTACAAAAGTTCCCGATACAAAAGGATGCTTTCAGTGTTGCGTTATACGGAATCCTT
ATAATGGTTATAAATATTTAGCGGGTAGACTTTCATCTGGTATATTTCTCATGCAGTGGT
ATGATCCATTGAATAAGTTTATGTTATTGAAGCAATGTGAATGGCCTGCTCACAGTTTGC
CTATGAATGATAATTCAGTATTTGAAATGATAATTTTGCCAGAATTGGAATATCCGCTAG
TGTGTGTGGGAGTCTCGAAATCATACGGAGGCAACGGCTTGAAACTTGAATTGTTCAATA
CAAATACTGCTGGCTGGTTCAGTTTGTCATATGATGACGATGATTTTTCAGATATGGATA
GAACTGCAACAATGATTCCAAAACGACTTCCAATGAAAATTATTAAAGTGCATCAGATGG
AAAAAGATATCATTGCAATCGTGCACGATAATGTTATAGAAATGGTAGATTTAAGTGGAC
AACCAAAAACTTCTAAGAAAATTGGTCTCTCAAAATCTGAGTTTGGCTTTAAAGTTGAAG
GAATGGTGATAGTTCAAAATGATAGCATTTTGGCATTTCATTCTCACGGAATGCAAGGAA
GATCTCTTAGAAATGGTGCCATTACGCAGGAAATTACAGATACGAGTAAAGTTTATCGAT
TATTAGGAAGTGAAAAGGTTGTGTGTCTCGAGAGTAGTCAAAAAAGAAGCAATAATAATG
ATGGAAGTGCATCAGAAGAGTTTCACGATCTGTACACTTTGGCTGGTCATGAAGCTAGTT
ATTAGAAGTTCTTTCATCTTAATTCCGAATAAAAGTCATTTTAATAAGCAGCAACAATTA
TAAGAACAAAACAGATTTAAAAAAGTTTAGGACATATTAAACACCATTTAATTAAAGTAA
AACGTAATGTAGGAAACGTACTACAAAGATGATATTACCTTAGAACATACATAGAGTGCA
GGGAGAGACCAATAATGTTCACAATTTGACGCAAATAAATATATTTAATTAAAATATGTC
GTTTTTGATGGAATATAAAAATTTGAAACATTCACACACAAAAAAAGAAGTTATAATAAT
TCATGTCACATGTTCAGAAGATCGTGAGAGAAAAACAAAAAGTTATGTTTTTTAAAATTC
TTAGATGTTTAATGCAAGTCATTATCTTTTAAATCCTGATAATAAAGATGAAAATTATTT
TCTAGTTTAAATTAAATTTC
>g12126.t5 Gene=g12126 Length=378
MGACFSKVFNGCPLHINCTASWINPETRDQHILIGADEGIFTLNMNEIHDAVIDQIYPRK
TIWLYVIKDVLMSLSGKSSQLYRHDLVALHSKQATSRFTLQLHMQKIPEKLVPRKFALTT
KVPDTKGCFQCCVIRNPYNGYKYLAGRLSSGIFLMQWYDPLNKFMLLKQCEWPAHSLPMN
DNSVFEMIILPELEYPLVCVGVSKSYGGNGLKLELFNTNTAGWFSLSYDDDDFSDMDRTA
TMIPKRLPMKIIKVHQMEKDIIAIVHDNVIEMVDLSGQPKTSKKIGLSKSEFGFKVEGMV
IVQNDSILAFHSHGMQGRSLRNGAITQEITDTSKVYRLLGSEKVVCLESSQKRSNNNDGS
ASEEFHDLYTLAGHEASY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 2 | g12126.t5 | PANTHER | PTHR48012:SF18 | HAPPYHOUR, ISOFORM A | 1 | 358 | 0.000 |
| 3 | g12126.t5 | PANTHER | PTHR48012 | STERILE20-LIKE KINASE, ISOFORM B-RELATED | 1 | 358 | 0.000 |
| 1 | g12126.t5 | Pfam | PF00780 | CNH domain | 24 | 338 | 0.000 |
| 5 | g12126.t5 | ProSiteProfiles | PS50219 | Citron homology (CNH) domain profile. | 13 | 344 | 19.466 |
| 4 | g12126.t5 | SMART | SM00036 | nik_2 | 18 | 351 | 0.000 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
There are no GO annotations for this transcript.
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
