Gene loci information

Transcript annotation

  • This transcript has been annotated as Serine/threonine-protein kinase Smg1.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g12129 g12129.t1 isoform g12129.t1 21203400 21212391
chr_1 g12129 g12129.t1 exon g12129.t1.exon1 21203400 21203627
chr_1 g12129 g12129.t1 cds g12129.t1.CDS1 21203400 21203627
chr_1 g12129 g12129.t1 exon g12129.t1.exon2 21205602 21205643
chr_1 g12129 g12129.t1 cds g12129.t1.CDS2 21205602 21205643
chr_1 g12129 g12129.t1 exon g12129.t1.exon3 21205713 21205855
chr_1 g12129 g12129.t1 cds g12129.t1.CDS3 21205713 21205855
chr_1 g12129 g12129.t1 exon g12129.t1.exon4 21205920 21207347
chr_1 g12129 g12129.t1 cds g12129.t1.CDS4 21205920 21207347
chr_1 g12129 g12129.t1 exon g12129.t1.exon5 21207477 21211337
chr_1 g12129 g12129.t1 cds g12129.t1.CDS5 21207477 21211337
chr_1 g12129 g12129.t1 exon g12129.t1.exon6 21211425 21212391
chr_1 g12129 g12129.t1 cds g12129.t1.CDS6 21211425 21212391
chr_1 g12129 g12129.t1 TSS g12129.t1 NA NA
chr_1 g12129 g12129.t1 TTS g12129.t1 NA NA

Sequences

>g12129.t1 Gene=g12129 Length=6669
ATGGACAAATATGGTGAAAGTAAATCAAATAGAAATCGATGGAAGGATGAACATCGTCAT
CCAAAATTGTATGATGAACGACTGGACACTCCAGGACAACAACAAAATGGAAAAATTACT
ACTGCCAGTTCCTCATCTTCTTCTTCAAAGACACAAAGTAGTAATAGCAGCAGTAATAAA
CTTTTGAAAACTGACATAGTCAATCAACTAGCTCAAAATCCAAATCTTCCTGAGGATGTT
CGCATTTCAAAGTTGTTGCGACGTTTAGAGACGGAAACTACTGTAACTGGAACAATTGAA
ATTTGTGGAAAACTTAAAACAGTCGTTCAAGACCAAGCAAATGCCAATTACATCAAGCGA
TCGTTTGACATGCTCACCAATTCATTAATTTCGGTTATGAAGGAATGTCACACAGGTGAA
GCAGTCAATCATGTTGCGGAAGTATATGGAATGATGGGTTTTGTGATGAGAAATGATTTT
CCTCTTTATAAATCATGGATTTGCAAGACTTACAAGAATGTTAAAACACTTCGTGTCGCA
ATGATGAAAGCTTTAGAAAAAACTCTCACAATGGACTCAAATGAGCTACGATTGAGTGAT
CAAATAGGAAGATTGATGGAATTATTGAGAGATTTTCTTGAACAGACTGATGATTATCGA
GTTTTTATGGCTATCACAAATGTTTTAATTGTCATTGCTAATAATTATAATATGAGATAT
TTTAAGTCACATTTTACAAATGTGGTCGATATTGTAATTGGTTGGATGATGGAAAATCAA
TTGACAAAAGTGAAAGTTCATTGTGCAGTTGTTTTACAAAGTTTGGGACAATTTTGGAAA
AATGATTCACAATTTTCACTTGATCTTATTGGTCAACTTTTAGAAGATATCGATGGATGC
ATTGAAAAAATGGAAGACAGCAACGAAGATAAAGTTAAAAATTTTAAAGATTTTGGTGCA
TTTGTTGGTGTCTTCAATGCGATAATAAAATCAGTTTATGTTTCGCCCGAAGCATTAATT
TATTTTATGGGAAAATCGACAATGGAAGGGTGCAAAGAAAAGATTTTTCGAGTAGCACAG
TTTGCCTTAAATAATGAAAACTGCATCAAAGAGACAGTTTTACCAGTGAATGAATACATA
TTAATTGTTCTTAATTGCCGCAAGTGTGAAATTGGAATAGAAATGAACTCAATTCTGACA
TTGATTGAAATCGAAATGGAAAATTTAACAAAATTTACAGAAAGTGAATTGGCTAGTTTC
CTTTGTGTCGTTAATGAATTTATCAAAGAGTTCAAAAGTGAACTTCCTGTGCAATTTATT
GAAAAGCTTTTCAATGTTGATAGTGTGCTGATTCAAAGTGTCAGTTTCAATAACGATAAA
CGAGTGAAAAGCGGATTAATTAAAATTTATCATGAAGTTCTTGCATTGAAAAATGTTCCA
TTATTACAAGCTGCATATAGATGTATAATTGAACAATTTGGCGTATGCCTTAAGCGAATT
CCACAATTAAAGGAAATTAAATGGATTTCCGATGTGGTGTCTAATTTGGTTAATAATGAA
ATAACTAATGAGAAAACAATTCTGAGAGCACAAGTTGCATTGAATTTTAATTTAACTGCT
CTTTCAAAATTGGCCACAACGCAAAATTCAATCATTGCCATGTATTCGCTTGTTCCGAGT
ATTTTAGAAGTATTGATAAATTTGCAAATTTGGCGATCTGAGTGGAATGAGTTTGAATTG
ACACAATATGCAATTTTGCTGGTAATTTCGGAGCATTGTCTGAAAAATAACAATTTTATT
TCATCAAGTGCACTGCTAATCAACAAAACTTCAACAATAACTACATCTTCATGGCTTTCT
GATTCGTCGCCAACGGAATCACCTGTTTCGCAACACTTCAAACTTATTCTTGAATTTATT
GATAAAATGCTCAAGTCTTCACCATCATTAAAACAATTCAAATTGATTCTTGATTGGCTT
GATAAAATCATTCAGCAAACATGTCAATATTCTGAACAATTAAAAGAAAATTCAAGTTTT
GTATCAATTCTGAAGCGAATAAATCAAATCGCAAATAATTATAAGAATGATGAAGTAATG
CTAAAGGTCGCAACATGTAATGATTCACTCTATTCCTTTGAGAGCATTCACAATGAAATT
TACACCGCTATGTCTGAAGCAGGTGTTGTACAAATGTGCTCAACAAATCCAGAAATAAGA
CGCCGTTATTCCTTCATTCTCTCGCGTATTCCGTTGAAATTTACGCTCGAACAAGCCAAG
TCACCATCGGGCATAAATCAAGAGACTATTAATAAAATCACCGAGATGGAAAACTGGCAT
CTATCACTCGGCAGCATTCATGGAGGAGAATTGCGCGCTCAATATTTCCAAAAATTCATA
AATCATATAACTTATTCGCCAAATGCCGCTAATATTGATCAGTTTATTTTGCATGCATTC
AGAAATTGTTGGTTTAATGGGACCGAAATGGCTGAAGAATATAAGCGAGTAACATTAAAG
GATGTTCGAACATTGTACTCTTGGATGCAATGGGAAGCAGCTCGCTTTTGTGTCAACAAT
AAATTACGAACGCCGCTGGGCAAGGCACAGGACACTTTCATTAAAATTGAAGGGATAATT
CGAGAGCACGCTCGTATTCTTACGCTCAAGGACAAGTCGAAACTGCGTGGTTATGAGCAC
GTCTTGGCAAATCAACGCAACGTGCGAATTCTTTTAGGTTTTATGGAAAGTTTAGAGAAA
GCTATTTATAATGCGGCAGAGGGTAGTGCTTTTGCAATACCACCTCCAGAAAAGCCAGCA
AGAACATTTTTCCGACTGAATGCGTCAACTTGTAATGAATGGTTTAATCGCAATCGACTT
GCAATTCATCAGTTAGCACTTCATGCACTAGAACTTGAGATGGTAATTAGATGTTCACAA
AGCATTTTAAAGGAAATGTGTGCTGCCGGAAAAATAAATGAGACTTATTTTGATCAAATA
TTAATGTCATTAACATGGGCCATGTTACGAAATTTCGAAAGCGACAGTCTATGTGGTTTG
TATGTTTGGGTAAAAAATGTCTCTGGTAGAAAATTACATTGGATTAAAATGGCAGCGGAA
CAAGCTGCAGGACATCGTGAAGTAGCAGCCGATGGTTATACAAAAGTTCTAAAAGATGAA
AAACTCGAACCGAAAATTTATGATTTCATTGCGGATCAAAGAAGATGTTGCTTGTTGTTT
ACAGGAAATATGGAGGAGTTGTATAATGTTTTGGTTGAAGAAGAAGAGAGAAATTATAAG
CCAACAAATATTCCAATATTAAAAATCACAAAGGAACAGGTGGCCAGTATCAAGAAATAT
GACAAGACGAAGGACTTTGATGCACTTAATGATTTATCACTGTGGGAGACGCTTGAGGAT
GAAGGAAATGTTTCAAACAACTTTTCAGTGCATAATTTACTCTCATTAACTGAGAACACG
CTCTCATGTGCCATATTAGACAAAGAGAATAGCAATCGAGATAAAGAGAAGACAAGCTGG
GAAATTTTGCACACTTTATTGCAAGAGAGCATTAGAACAAGTTCACAAGAATATTTAATT
GGACTAAATGTATTGAATCACATAGCACACAAATACAAAATAGTCATCAATAATGAAGGC
AGTGTCAATATTGAGTCACTCGAAATTGAGAAGAAATATGGTTCGTTGACAATGTTTTTT
GTTTCAATTTATGGTGAATTTCTCGACGCATGCAGCGAGAAGGGTGAACAACAAAATATC
AATCTGAAATTAGATTTGGTCGCATCTGCACGCAAAGAATTAAATTTTCGACAATGCACT
CGTGAGCTATCATCAGTTTATCGAAGTGTAGAATATACAGAGCACATAGGTCTCCCATTT
GAGCACGAATTGTCATCGATAAAAGAATTTTTCATGTCACCACGCAATGTCAAAGATAGT
AAAATTTGGTCTGAAAATGTATCACGTGCGATTTATGAGCATTGCAAAATGCTTTATGTT
GCGAAAAATCAACATTTTGATGCTATACAATTTGCTTCAACCGCAGCACTCGGTATTAAA
AATAGACTAAACATAACTGATGGCAATGTTTCTGAAAATTTAAATCAACAGTGCGTTAAA
TTTTACACGAAAATTTCAGAATGGATCCAAAATGAGCCCGAGGAATCACTGTTTTCACAC
GATGGTAACTCGCTAAATTCACTCGTGCAGTCAATAAATGATGAAGAATATATAGACGAA
CAAATGCCATTAGTTGATTCTGCGGTCGGAAAACTTCTTCAAAGTGGTGTAAAACAATGT
CCTGAAATGCCTAAAGCTTGGTCAAGTCTTGCAAATTGGTGCTATAAATGGGGCAGAAAA
ATGATTGAATCAAAAACCGACAGTCAAGGTCTTCGAGCCATCGACTCAAGTGCAATTGTA
GATTTAATTCCTGAAGCGCAACCGGAAGATGTTGAGAGTATCTTGAAAGTTCTAAACGAG
CAGCAAATTATGGTCGAGGACGAAGATATTGGACCGAATGAAAGTAGCTCAACAGAAATT
ATTGAGAGCAACTTGAGAATGATTTCATTGTTGAAAAACAAAAATAGTGACATCATTAAT
AGTATCATCACACTATGGAAGCAAGCTCATCGTGATGTGTACAAATATTATGAGATGTGT
GCTAGTGCTTACTTTAAATTTCTTTTATTATCATCAAGTAATACCGACATGAATAGCGAT
TCGTCAGTTGTCACTGCTACACTTCGCTTATTGCGGTTGATTGTAAAACATGCGTTAGGT
CTGCAAGAAATTTTAGAAGAAGGTTTAGCGATAACTCCTTCAGGTCCCTGGAAAGTGATA
ATACCACAATTATTTTCACGATTGGATCATCATGAGCCTTACGTGAGAAAACGTGTAAGC
GAACTTTTATGTCGTGTAGCTAGCGACTCACCTCATTTAATCATTTTTCCAACTGTTGTC
GGAGCGGCTCATAATCATTTAGAAGAAGAAAAGTTTAAAGCTCAGCCAATTGAAGACAGC
AAAATCTTGAGCGATTGCAAAAAGTTTCTCAATTCGAGCTTATCTTACTGCTTCACTTCA
CTTCTCAACACATTATCGATGCAAAGCCCTCAAACTGTCAGCCAAGTGCAACTTCTTGTT
AACGAACTTCGCAGAATTTCCATGTTGTACGACGAAATGTGGCTCACAACTCTTAACCAA
CTCTATGTTGAAAATGCCAAAAAGTTTGTGAACTTTGATGCAGAATTTCAAGCTACTGAC
AAGTCGCAAGAGAAAATAAATTTATTCGCGGAAAAATACAAATTGCTAACGAAACAAATG
TTATTCATCATGGAATGCATGCAGGATTGGACATCCAAACCGCCAGAAACAAACAATGAG
CGCGCTTTTCAAGAGAAATTTTCGCATTTTATCGAAATGACAATTGGCGAGTTGAAAAGA
CCATTCGACTCAAGTGAACCGCTTGCTGCATTCAACAAATTCAAATCTTTATTGCATTTG
ATGCAACAGCGTGTACATAAGCGTATGAATCACACGTTAAAGATGAGTGATATTTCACCA
ATTCTCGCGAATTTAAATAACACAAATATTTCAATGCCAGGGGTTTTGCCTTCAAATGAT
AGCGAAGCAGTTTACATTCAGTCAGTCGACGAGACAATTCAGATTTTACCAACAAAAACA
AAACCCAAAAAGCTCGCATTTTATGGCAGTGATGGTAAACGTTATACATTTCTATTCAAG
GGCATGGAAGATTTGCATTTGGATGAACGCATTATGCAGTTCTTGTCGATTGCTAATTTA
ATGATGAAAAAATCAGTGGATTCTGATGGTAAAGTCACTTACTATCGAGCACATCATTAT
TCTGTCATTCCATTAGGACCAAGATCTGGTTTAATATCATGGGTTGATGGCGTGATTCCA
ATATTTTCCATTTACAAAAAATGGCAACAAAGAGAAGCCGCAAATCCTCGGAAAGACAAG
CAATACGTTGTCATGCGACCATCAGAGTTATTTTATAGCAAAATTACGCCTCTTCTGAAA
GAACATGGCCTGAAGCCAACTGACAATCGAAAGGACTGGCCTGTGTCTGTTCAAATGAAA
GCTTATGAAGAACTCAAGTCAGAAACTCCACGAGATTTACTAGCAAAAGAATTTTGGTGC
ACTGCATCGACTTCTGCACATTGGCGACAAATAGTTAGAAATTATTCAGTGTCACTTGCA
GTAATGAGCGTAATTGGTTATATTATTGGGTTGGGCGATAGGCATTTAGATAATATCCTT
GTCAAGTTAGCTAGTGGAGACATTGTCCACATTGACTACAATGTGTGTTTTGAAAAAGGC
AAAACATTGCGAGTCCCAGAACGAGTTCCATTCAGAATGACACAAAACATTGAAGAAGCT
TTAGGACTAACAGGCATTGAGCTTGCTGTTGATGATAGTGGTTTTGATGAAGTTTTGAAT
CGTATTATTTTTATTACTGTAACGATGATATGCCTTGAATATATTTATTTAGAACTTTTT
CTTCCCTATGGAATTTTTCTTTCTTCGAATGACTTCTCTAATACACGTACATATAACATC
ATAAGTGACTTTATGCCGAAAGTATTTTATCTTACATCTGAGATGACTTGCCATCTTGAC
AGTGATTGA

>g12129.t1 Gene=g12129 Length=2222
MDKYGESKSNRNRWKDEHRHPKLYDERLDTPGQQQNGKITTASSSSSSSKTQSSNSSSNK
LLKTDIVNQLAQNPNLPEDVRISKLLRRLETETTVTGTIEICGKLKTVVQDQANANYIKR
SFDMLTNSLISVMKECHTGEAVNHVAEVYGMMGFVMRNDFPLYKSWICKTYKNVKTLRVA
MMKALEKTLTMDSNELRLSDQIGRLMELLRDFLEQTDDYRVFMAITNVLIVIANNYNMRY
FKSHFTNVVDIVIGWMMENQLTKVKVHCAVVLQSLGQFWKNDSQFSLDLIGQLLEDIDGC
IEKMEDSNEDKVKNFKDFGAFVGVFNAIIKSVYVSPEALIYFMGKSTMEGCKEKIFRVAQ
FALNNENCIKETVLPVNEYILIVLNCRKCEIGIEMNSILTLIEIEMENLTKFTESELASF
LCVVNEFIKEFKSELPVQFIEKLFNVDSVLIQSVSFNNDKRVKSGLIKIYHEVLALKNVP
LLQAAYRCIIEQFGVCLKRIPQLKEIKWISDVVSNLVNNEITNEKTILRAQVALNFNLTA
LSKLATTQNSIIAMYSLVPSILEVLINLQIWRSEWNEFELTQYAILLVISEHCLKNNNFI
SSSALLINKTSTITTSSWLSDSSPTESPVSQHFKLILEFIDKMLKSSPSLKQFKLILDWL
DKIIQQTCQYSEQLKENSSFVSILKRINQIANNYKNDEVMLKVATCNDSLYSFESIHNEI
YTAMSEAGVVQMCSTNPEIRRRYSFILSRIPLKFTLEQAKSPSGINQETINKITEMENWH
LSLGSIHGGELRAQYFQKFINHITYSPNAANIDQFILHAFRNCWFNGTEMAEEYKRVTLK
DVRTLYSWMQWEAARFCVNNKLRTPLGKAQDTFIKIEGIIREHARILTLKDKSKLRGYEH
VLANQRNVRILLGFMESLEKAIYNAAEGSAFAIPPPEKPARTFFRLNASTCNEWFNRNRL
AIHQLALHALELEMVIRCSQSILKEMCAAGKINETYFDQILMSLTWAMLRNFESDSLCGL
YVWVKNVSGRKLHWIKMAAEQAAGHREVAADGYTKVLKDEKLEPKIYDFIADQRRCCLLF
TGNMEELYNVLVEEEERNYKPTNIPILKITKEQVASIKKYDKTKDFDALNDLSLWETLED
EGNVSNNFSVHNLLSLTENTLSCAILDKENSNRDKEKTSWEILHTLLQESIRTSSQEYLI
GLNVLNHIAHKYKIVINNEGSVNIESLEIEKKYGSLTMFFVSIYGEFLDACSEKGEQQNI
NLKLDLVASARKELNFRQCTRELSSVYRSVEYTEHIGLPFEHELSSIKEFFMSPRNVKDS
KIWSENVSRAIYEHCKMLYVAKNQHFDAIQFASTAALGIKNRLNITDGNVSENLNQQCVK
FYTKISEWIQNEPEESLFSHDGNSLNSLVQSINDEEYIDEQMPLVDSAVGKLLQSGVKQC
PEMPKAWSSLANWCYKWGRKMIESKTDSQGLRAIDSSAIVDLIPEAQPEDVESILKVLNE
QQIMVEDEDIGPNESSSTEIIESNLRMISLLKNKNSDIINSIITLWKQAHRDVYKYYEMC
ASAYFKFLLLSSSNTDMNSDSSVVTATLRLLRLIVKHALGLQEILEEGLAITPSGPWKVI
IPQLFSRLDHHEPYVRKRVSELLCRVASDSPHLIIFPTVVGAAHNHLEEEKFKAQPIEDS
KILSDCKKFLNSSLSYCFTSLLNTLSMQSPQTVSQVQLLVNELRRISMLYDEMWLTTLNQ
LYVENAKKFVNFDAEFQATDKSQEKINLFAEKYKLLTKQMLFIMECMQDWTSKPPETNNE
RAFQEKFSHFIEMTIGELKRPFDSSEPLAAFNKFKSLLHLMQQRVHKRMNHTLKMSDISP
ILANLNNTNISMPGVLPSNDSEAVYIQSVDETIQILPTKTKPKKLAFYGSDGKRYTFLFK
GMEDLHLDERIMQFLSIANLMMKKSVDSDGKVTYYRAHHYSVIPLGPRSGLISWVDGVIP
IFSIYKKWQQREAANPRKDKQYVVMRPSELFYSKITPLLKEHGLKPTDNRKDWPVSVQMK
AYEELKSETPRDLLAKEFWCTASTSAHWRQIVRNYSVSLAVMSVIGYIIGLGDRHLDNIL
VKLASGDIVHIDYNVCFEKGKTLRVPERVPFRMTQNIEEALGLTGIELAVDDSGFDEVLN
RIIFITVTMICLEYIYLELFLPYGIFLSSNDFSNTRTYNIISDFMPKVFYLTSEMTCHLD
SD

Protein features from InterProScan

Transcript Database ID Name Start End E.value
7 g12129.t1 Gene3D G3DSA:3.30.1010.10 - 1828 1976 4.0E-12
8 g12129.t1 Gene3D G3DSA:1.10.1070.11 - 2035 2165 2.5E-24
17 g12129.t1 MobiDBLite mobidb-lite consensus disorder prediction 1 27 -
18 g12129.t1 MobiDBLite mobidb-lite consensus disorder prediction 1 60 -
16 g12129.t1 MobiDBLite mobidb-lite consensus disorder prediction 29 60 -
3 g12129.t1 PANTHER PTHR11139:SF108 AGAP000368-PA 104 2131 1.1E-275
4 g12129.t1 PANTHER PTHR11139 ATAXIA TELANGIECTASIA MUTATED ATM -RELATED 104 2131 1.1E-275
2 g12129.t1 Pfam PF15785 Serine/threonine-protein kinase smg-1 554 1138 1.1E-124
1 g12129.t1 Pfam PF00454 Phosphatidylinositol 3- and 4-kinase 1915 2147 3.6E-41
10 g12129.t1 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 1 2161 -
11 g12129.t1 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 2162 2186 -
9 g12129.t1 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 2187 2222 -
13 g12129.t1 ProSitePatterns PS00916 Phosphatidylinositol 3- and 4-kinases signature 2. 2078 2098 -
20 g12129.t1 ProSiteProfiles PS51189 FAT domain profile. 1364 1664 10.089
19 g12129.t1 ProSiteProfiles PS50290 Phosphatidylinositol 3- and 4-kinases family profile. 1915 2137 32.374
14 g12129.t1 SMART SM01345 Rapamycin_bind_3 1722 1844 3.4E-4
15 g12129.t1 SMART SM00146 pi3k_hr1_6 1916 2222 5.6E-13
5 g12129.t1 SUPERFAMILY SSF48371 ARM repeat 1527 1684 3.96E-5
6 g12129.t1 SUPERFAMILY SSF56112 Protein kinase-like (PK-like) 1830 2147 8.77E-67
12 g12129.t1 TMHMM TMhelix Region of a membrane-bound protein predicted to be embedded in the membrane. 2165 2187 -

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0016310 phosphorylation BP
GO:0004674 protein serine/threonine kinase activity MF
GO:0016301 kinase activity MF
GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay BP

KEGG

Orthology

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values