Gene loci information

Transcript annotation

  • This transcript has been annotated as Scoloptoxin SSD14.

Parent gene

Gene structure

  • The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.

Chromosome Gene Transcript Category ID Start End
chr_1 g12193 g12193.t3 TTS g12193.t3 21679610 21679610
chr_1 g12193 g12193.t3 isoform g12193.t3 21679814 21682921
chr_1 g12193 g12193.t3 exon g12193.t3.exon1 21679814 21681300
chr_1 g12193 g12193.t3 cds g12193.t3.CDS1 21679814 21681300
chr_1 g12193 g12193.t3 exon g12193.t3.exon2 21681361 21681605
chr_1 g12193 g12193.t3 cds g12193.t3.CDS2 21681361 21681484
chr_1 g12193 g12193.t3 exon g12193.t3.exon3 21682910 21682921
chr_1 g12193 g12193.t3 TSS g12193.t3 21682989 21682989

Sequences

>g12193.t3 Gene=g12193 Length=1744
ATGGATTTGTGAAACAAATATTTCTCGAAAGCGAGTTTTTATTGCTTTATTCATATCAAT
CATAATAATTGTCGCTATAATCACCGCCTACCAGTTTGGTATTAAAAATGATGATGAGCC
AAAAACAAGGCTTATGCATGGTGGTGCTGTTGCAGCTAATGGGAAAGAATGTGCTGAATT
AGGTGCAAATATTTTAAAACAAAAGGGATCAGTAGCTGATGCTGCTATAACAACTATGCT
TTGCGAAGGAATCACTTGTCCGCAGTCAACTGGGCTAGGTGGTGGTTTTCATTTGACAAT
TTACATTAAGAGCAAAAATTTAGTCGAATGTCTCGATGCTCGTGAAACTGCACCTAAAAA
TTCCCACCAACAAATGTTTGTTAATGATACGAAAAAATCGTCACTCGAAGGTGGTTTATC
AATCGCAGTCCCAGGAGAACTTAAAGGAATGTGGGAATTGCATCAACGCTATGGTAAACT
TCCTTGGAAAGACCTTTTCAAACCAGTGATTGATTTATGTCAGAATGGACATGAAGTAAC
TGAATATTTGGCACGAGTTTTGAGTAAAAAGAGTGAAGACATCAAAAACATTCCATCGCT
TCGAGAAGTATTTGTCAATCCACAAACGGGAGAATTATGGAAAGCAGGAGATAAAATTAA
AAGATTAGCATTAGCAAAAACACTTGAGACAATTGCAAATGAAGGTGCTGATACAATGTA
TAGTAAAAATGGAACTATTGGTCGCCAAATTTTAGAGGACATCAAGGAATTTGGTGGAAT
TTTAACAGAAGAAGATTTTACTAATTATAAAGTGAAATGGTTAAAACCAGCTGAAACAAC
TTTGAAAAATGGCGAGCGTCTTTATTCTATGCCTTTATCAGGTTCAGGTGCACTTTTAAT
TTTCATTATGAATTTATTAAAACCTTATGATTTAAAAAATGATGTTTTGTCGAACCATCG
TATAATTGAAGCTTATAAATTGGCATATGCTCGACGATCAGAACTTGCAGATCCTGCATT
TGTCGAAAGTGCTGAAATTTTGATTAGAAATTTAACCAACATTGACTATGCTAATGTAAT
GAGAAAGAAAATTGATGATACAAGAACACACAATGATATTAATTATTATGAAGGACATTT
TATATCACAAGAAGACCATGGAACTGCTCATATTAGCATTCTTGCACCCAATGGTGATGC
AATTTCAGTTACTGGAACAATAAACTATATTTTGGGTTCAATGAGAAGAAGTAAAACTGG
AATTATTTTAAATGATGAAATGGATGATTTTAGTACACCTGGTCAAAAGAACATTTATGG
CATTTCACCTTCAGAAGCAAATTACATTCAACCAGGAAAGCGACCAATGTCTTCAATGGC
TCCATCGATTGTTGTTAATAATGATGGAAATGTCGGATTAATAATTGGAAGTGCTGGAGG
CTCTCGAATAACAACTGCTATCGCTCACACAATCATTCAATATTATTTCCTAAAATCAAA
AGATTCACTTTGGAATACTTTTTCAATGAAACGACTTCATCATCAATTATTGCCTAATAA
AATTTACTTTGAAGATGGGTTTGATGAGCAAATAATTAATCAATTGAACAAAACATTTAA
TCATGACGTTGAAAGAGTTATAGAGCCTATAGGCTTTGGGGCGCTTGTGGGCATTTATGC
TGACAATGAATCAGTTCAAGGAGCTTACGATCCAAGAAGAGGTGGAAGTTCTGTGGTTTT
TTAA

>g12193.t3 Gene=g12193 Length=536
MHGGAVAANGKECAELGANILKQKGSVADAAITTMLCEGITCPQSTGLGGGFHLTIYIKS
KNLVECLDARETAPKNSHQQMFVNDTKKSSLEGGLSIAVPGELKGMWELHQRYGKLPWKD
LFKPVIDLCQNGHEVTEYLARVLSKKSEDIKNIPSLREVFVNPQTGELWKAGDKIKRLAL
AKTLETIANEGADTMYSKNGTIGRQILEDIKEFGGILTEEDFTNYKVKWLKPAETTLKNG
ERLYSMPLSGSGALLIFIMNLLKPYDLKNDVLSNHRIIEAYKLAYARRSELADPAFVESA
EILIRNLTNIDYANVMRKKIDDTRTHNDINYYEGHFISQEDHGTAHISILAPNGDAISVT
GTINYILGSMRRSKTGIILNDEMDDFSTPGQKNIYGISPSEANYIQPGKRPMSSMAPSIV
VNNDGNVGLIIGSAGGSRITTAIAHTIIQYYFLKSKDSLWNTFSMKRLHHQLLPNKIYFE
DGFDEQIINQLNKTFNHDVERVIEPIGFGALVGIYADNESVQGAYDPRRGGSSVVF

Protein features from InterProScan

Transcript Database ID Name Start End E.value
15 g12193.t3 Gene3D G3DSA:1.10.246.130 - 232 337 1.6E-26
14 g12193.t3 Gene3D G3DSA:3.60.20.40 - 338 536 1.9E-60
2 g12193.t3 PANTHER PTHR11686 GAMMA GLUTAMYL TRANSPEPTIDASE 3 533 1.0E-213
3 g12193.t3 PANTHER PTHR11686:SF51 GAMMA-GLUTAMYL TRANSPEPTIDASE, ISOFORM A 3 533 1.0E-213
9 g12193.t3 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 26 51 1.6E-66
10 g12193.t3 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 96 114 1.6E-66
5 g12193.t3 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 114 133 1.6E-66
11 g12193.t3 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 216 232 1.6E-66
8 g12193.t3 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 246 265 1.6E-66
6 g12193.t3 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 344 362 1.6E-66
12 g12193.t3 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 367 385 1.6E-66
7 g12193.t3 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 407 422 1.6E-66
4 g12193.t3 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 432 449 1.6E-66
1 g12193.t3 Pfam PF01019 Gamma-glutamyltranspeptidase 19 531 2.8E-160
18 g12193.t3 Phobius NON_CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. 1 242 -
19 g12193.t3 Phobius TRANSMEMBRANE Region of a membrane-bound protein predicted to be embedded in the membrane. 243 262 -
17 g12193.t3 Phobius CYTOPLASMIC_DOMAIN Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. 263 536 -
13 g12193.t3 SUPERFAMILY SSF56235 N-terminal nucleophile aminohydrolases (Ntn hydrolases) 2 535 1.06E-141
16 g12193.t3 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 6 528 2.4E-108

Transmembrane regions from TMHMM

Disordered region

IUPRED3 score over 0.5 is predictive of a disordered region.

GO terms from InterProScan

GOID TERM ONTOLOGY
GO:0006751 glutathione catabolic process BP
GO:0036374 glutathione hydrolase activity MF

KEGG

Pathway

  • This transcript belongs to the following pathways

Expression

Transcript expression in Pv11 cells

TPM values are indicated as average +/- STDEV.

Differential expression

Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.

Raw TPM values