General information for g12221.t1
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as Tyrosine aminotransferase.
Parent gene
- The parent gene g12221 is located on chr_1: 21795809..21797128 (+ strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12221 | g12221.t1 | TSS | g12221.t1 | 21795801 | 21795801 |
| chr_1 | g12221 | g12221.t1 | isoform | g12221.t1 | 21795809 | 21797128 |
| chr_1 | g12221 | g12221.t1 | exon | g12221.t1.exon1 | 21795809 | 21797128 |
| chr_1 | g12221 | g12221.t1 | cds | g12221.t1.CDS1 | 21795809 | 21797128 |
| chr_1 | g12221 | g12221.t1 | TTS | g12221.t1 | NA | NA |
Sequences
>g12221.t1 Gene=g12221 Length=1320
ATGCCAAACATTATAAGTGCCGATTGGAAGTTAGAGATGTCGACTTTTGCTCGACAGACT
GTCAACCCTCATCGTCTTATGGTTGAAACTTCAAAAGTTGTACCAAATCCTAAGAAAAAA
GTGCTTACATTGCAATTGGGTGATCCAACAATTTTTAAGAATTTTCAACATCCACCAGAA
GCAATTGATGCCATTAAAAATGCTTTGGTAAAAGATTCTTTCTCTTATTATCCAACAAAT
GGAATTAAAGAAGCTCGTGAAGCTGTAGCAGATTATGTCAGTAAAAATGGTGATCAAGTT
AATGCAGATGATATAATTCTAACAAGTGGTGGTTCAAGTTCTCTTGAATTGTGCTTTTAT
GTGCTTGCAAATCCTGGTGAAAATATTTTAATTCCAACACCTTCATTTAATTATAGAACT
TGGCTGCATGGACCTGGAATTATTTCAAAAACTTACAAGTTAGACCCAACAAAAAATTGG
TGTGTAGATTTGAAAGATTTAGAGTCGAAAATTGATAACAAAACTCGAGCAATTCTGGTT
AATAATGTTGGAAATCCTTGTGGAAATGTTTTTACTAAAGAGCACATACTTGATATCCTC
GAAATTGCAGAACGTTATAGACTTCCAATAATTTCTGATGATATTTATGAGCATTTTGTT
TTTCCCGGTGTTGAATATTATTCTGTGGCTTCTTTATCAAAGAATGTGCCAATTTTGAGT
TGCTCTGGCTTAACTAAAAGGTTTATAATGCCAGGCATTCGAATGGGATGGATCAGTATT
CATGATCGTCATGATGCACTTAAAGAAATCAGAAAAGGTTTCACTCAAATGTTGGGAAGA
AATTTCGGACCAAATTGCACAGTTCAGAAAGCATTGCCTGAAATTTTGCAGAATGTTCCG
CAAACATTTTTTGATGAGACAGTTAAAAAGGTTCAACTTCATGCAATGACTGCTTTTAAG
TTATTGAAAAATATAAAAGGTTTAATTCCAATCGAACCACGTGGTGCTTTTTACATGATG
ATTAAGATTGAGTTTGAAAATTTTCCTAAATTTAAAAGTGATTTAGAATTTGTTGAAGCA
TTGACTGAGGAAGAAAGTGTTAAAGCATTTCCAGGTGGACCGTGTTTTGATTTTGCTGGC
TATTTTCGTTTTGTCCTCACAGTTCCACTAGATATGCTCATTGAAGCATGTCAGAGAATT
CAAGAATTTTGTGAACGGCATTATATGAATATAAATGAAATAGAAAATTTTGAACCAGTT
CAAACTCAGGAAATTTCAATACAAAATCAAATTAACAAAATTGAAATCGCAATTTATTAA
>g12221.t1 Gene=g12221 Length=439
MPNIISADWKLEMSTFARQTVNPHRLMVETSKVVPNPKKKVLTLQLGDPTIFKNFQHPPE
AIDAIKNALVKDSFSYYPTNGIKEAREAVADYVSKNGDQVNADDIILTSGGSSSLELCFY
VLANPGENILIPTPSFNYRTWLHGPGIISKTYKLDPTKNWCVDLKDLESKIDNKTRAILV
NNVGNPCGNVFTKEHILDILEIAERYRLPIISDDIYEHFVFPGVEYYSVASLSKNVPILS
CSGLTKRFIMPGIRMGWISIHDRHDALKEIRKGFTQMLGRNFGPNCTVQKALPEILQNVP
QTFFDETVKKVQLHAMTAFKLLKNIKGLIPIEPRGAFYMMIKIEFENFPKFKSDLEFVEA
LTEEESVKAFPGGPCFDFAGYFRFVLTVPLDMLIEACQRIQEFCERHYMNINEIENFEPV
QTQEISIQNQINKIEIAIY
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 10 | g12221.t1 | CDD | cd00609 | AAT_like | 47 | 402 | 0 |
| 5 | g12221.t1 | Gene3D | G3DSA:3.90.1150.10 | Aspartate Aminotransferase | 43 | 404 | 0 |
| 6 | g12221.t1 | Gene3D | G3DSA:3.40.640.10 | - | 59 | 299 | 0 |
| 2 | g12221.t1 | PANTHER | PTHR45744 | TYROSINE AMINOTRANSFERASE | 12 | 411 | 0 |
| 3 | g12221.t1 | PANTHER | PTHR45744:SF2 | TYROSINE AMINOTRANSFERASE | 12 | 411 | 0 |
| 9 | g12221.t1 | PIRSF | PIRSF000517 | Tyr_transaminase | 3 | 423 | 0 |
| 1 | g12221.t1 | Pfam | PF00155 | Aminotransferase class I and II | 40 | 400 | 0 |
| 4 | g12221.t1 | SUPERFAMILY | SSF53383 | PLP-dependent transferases | 17 | 407 | 0 |
| 7 | g12221.t1 | TIGRFAM | TIGR01264 | tyr_amTase_E: tyrosine aminotransferase | 9 | 408 | 0 |
| 8 | g12221.t1 | TIGRFAM | TIGR01265 | tyr_nico_aTase: tyrosine/nicotianamine family aminotransferase | 9 | 408 | 0 |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0009072 | aromatic amino acid family metabolic process | BP |
| GO:0009058 | biosynthetic process | BP |
| GO:0006520 | cellular amino acid metabolic process | BP |
| GO:0008483 | transaminase activity | MF |
| GO:0004838 | L-tyrosine:2-oxoglutarate aminotransferase activity | MF |
| GO:0003824 | catalytic activity | MF |
| GO:0030170 | pyridoxal phosphate binding | MF |
KEGG
Orthology
This gene did not have any KEGG ortholog annotations (KAAS, GHOSTZ).
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below. There were no conditions that were differentially expressed