General information for g12300.t3
Yuki Yoshida
22/1/2022
Gene loci information
Transcript annotation
- This transcript has been annotated as NPC intracellular cholesterol transporter 1.
Parent gene
- The parent gene g12300 is located on chr_1: 22261838..22265620 (- strand)
Gene structure
- The exon-intron structure of all isoforms are indicated below. CDS regions are colored in green. TSS and TTs that were predicted with CTR-Seq data are indicated in solid circle and squares, respectively. More specific data are shown in the table below.
| Chromosome | Gene | Transcript | Category | ID | Start | End |
|---|---|---|---|---|---|---|
| chr_1 | g12300 | g12300.t3 | isoform | g12300.t3 | 22254516 | 22265620 |
| chr_1 | g12300 | g12300.t3 | exon | g12300.t3.exon1 | 22254516 | 22254521 |
| chr_1 | g12300 | g12300.t3 | cds | g12300.t3.CDS1 | 22254516 | 22254521 |
| chr_1 | g12300 | g12300.t3 | exon | g12300.t3.exon2 | 22254890 | 22254966 |
| chr_1 | g12300 | g12300.t3 | cds | g12300.t3.CDS2 | 22254890 | 22254966 |
| chr_1 | g12300 | g12300.t3 | exon | g12300.t3.exon3 | 22255261 | 22255465 |
| chr_1 | g12300 | g12300.t3 | cds | g12300.t3.CDS3 | 22255261 | 22255465 |
| chr_1 | g12300 | g12300.t3 | exon | g12300.t3.exon4 | 22255535 | 22258065 |
| chr_1 | g12300 | g12300.t3 | cds | g12300.t3.CDS4 | 22255535 | 22258065 |
| chr_1 | g12300 | g12300.t3 | exon | g12300.t3.exon5 | 22258132 | 22258314 |
| chr_1 | g12300 | g12300.t3 | cds | g12300.t3.CDS5 | 22258132 | 22258314 |
| chr_1 | g12300 | g12300.t3 | exon | g12300.t3.exon6 | 22261099 | 22261288 |
| chr_1 | g12300 | g12300.t3 | cds | g12300.t3.CDS6 | 22261099 | 22261288 |
| chr_1 | g12300 | g12300.t3 | exon | g12300.t3.exon7 | 22261357 | 22261649 |
| chr_1 | g12300 | g12300.t3 | cds | g12300.t3.CDS7 | 22261357 | 22261649 |
| chr_1 | g12300 | g12300.t3 | exon | g12300.t3.exon8 | 22261838 | 22262003 |
| chr_1 | g12300 | g12300.t3 | cds | g12300.t3.CDS8 | 22261838 | 22262003 |
| chr_1 | g12300 | g12300.t3 | exon | g12300.t3.exon9 | 22262074 | 22262295 |
| chr_1 | g12300 | g12300.t3 | cds | g12300.t3.CDS9 | 22262074 | 22262295 |
| chr_1 | g12300 | g12300.t3 | exon | g12300.t3.exon10 | 22265561 | 22265620 |
| chr_1 | g12300 | g12300.t3 | cds | g12300.t3.CDS10 | 22265561 | 22265620 |
| chr_1 | g12300 | g12300.t3 | TSS | g12300.t3 | 22265942 | 22265942 |
| chr_1 | g12300 | g12300.t3 | TTS | g12300.t3 | NA | NA |
Sequences
>g12300.t3 Gene=g12300 Length=3933
ATGTCCATTAGATTTAAAACAAATTTAATAAATTTCATTCTCATACTTGGATTTTCATTG
GTATTTGGTCAAGCAACAACAACAACGTCGTCAACAGATAATGAGGGACATTGTGTTTGG
CGAGGAATTTGTGCTACTGATCCTCAGAAAAAAAATTGTGCCTATGATGGAAAAGCACTT
CCATTAGACAAAGAGGGTATTACAGAGCTGCAGGAATGGTGCTCGCATTTGATGCCTAAT
TCGAATAATAGTACTGTTTTGACATGCTGTGATATCGAACAGTTGAAAGAATTCAACTCT
CAGATAAAGTTAGCTGCTGCAATTCTAAATCGTTGTCCATCATGCATGAAAAATTTAGCC
AGACATATTTGTGATTTCACCTGTAGTCCGCATCAATCAGATTTTATAAAAGTCAAGAAA
ACTGGAATATCAGAGGACACTAATAAAACATATGTAGATGAGATAGACATTTACATAACA
GAAAAATATTTCAATGGAACATATGACTCATGTAAAAATGTCATCTATCCGTCGAGTGGA
CAACTTGCACTTGATTTAATGTGCGGATCGTGGGGTGCATCAAAATGTTCGCCTGCTAGA
TGGTTCGGTTATATGGGAGACGCTGTCAATAATCCATTTGTTCCATTTCAAATTAACTAT
TTGCCTCAAGATTCATCGAGTAGGAATGATGATATAAAGCCATTAGACTCAAAAGTCGTA
CCATGCAATCAGCCTGTGGATGATAAAACACCAGCCTGTTCATGTGTTGATTGCCAAGCA
TCATGCCCTAAGCCTCCACCACCAGATCCTGTTGTACGACCTTTTATAATTTGGGGTTTT
GACGGATATGCGGTCGTTATGTTTTTCATATTTCTTCTGGGAAGTTTAATATTCATCATG
GGTGCAGGATGCTGCTCAACTTCCGAAACTGGCCAATCGTCTGAAAACGATCAAGAATTA
ACAACACATCCGTCAGCAATTGTTGATAATGAACTTGGAGAGGAAAGTGGATATTTCGAG
AAGCTCGGAGCTAAAACAGAGCATGTTCTTGAACAATTTTTCACAGCGTGGGGAACGTGG
TGTGCAAACAATCCATGGAAAGTTTTATTACTCGGTTGTATTTTTATTGCATCCTTGGGT
TTTGGCCTTCTCTTCCTAAATGTCACGACAGATCCAGTTCAACTTTGGGCATCCCCTCAT
TCACGATCACGCATCGAACGAGAATATTTTGATACGCATTTTGGACCTTTCTATAGAATT
GAACAAATTATCATTACTACAAAAGATATTGCTCCTATTGTACATAATACATCAAATGGT
ATAGTTCATTTTGGTCCTGTTTTCAATGACACTTTTCTACTAAAAGTTCGTGAAATTCAA
GAATCAATAAAAAGTATCAAGCTTCAAAATTCTGATGATGATGAAGCACTTTCAAAAATT
TGTTATGCACCATTAAGATCACAATATTTTGAAGAAGATCAAAGTCAAAGTGTTAATGAT
TGTGTAATACAAAGTGTTTGGGGATATTTTAAAGATGATATTGATACTTTTGAAGAAATA
GATACAGATTCTGAAGGCTATACAATCAATTATTTGGATCATCTATTGCAATGCTTTAAT
AATCCTTATAATCCAGATTGTCTTGCACCATATGGTGGAATTGTTGATCCTGCTGTTGCT
TTTGGTGGTTTCTTAAAACCAGGAGATACATTATCGAAAAATCCAAATTATGAAAATGCA
ACATCAGTAATTCTCACATTTTTAGTCAACAATAATCACGACAAAACTAAGCTCAATGAT
ACACTAAATTGGGAAGAAATGTACGTCAAAGTTATGAAAAATTGGACAACAAATGCAAAT
ATAAGCTTTATGGATATTGCATTCACATCAGAACGTTCAATTGAGGACGAATTGTATAGA
GAATCGAAATCTGATATTTCAACAATTCTCGTGTCATATCTGCTGATGTTTGCCTACATT
GCTGTGTCATTAGGTCATGTAGATGTATGTAATCGAGCTTTGATTGACAGCAAAATTACA
CTTGGAATGGGTGGTGTGATCATTGTTCTTGCATCGGTCGTTGCCTCTGGTGGATTTTTT
GGATATATCGGTGTACCTGCAACTTTGATTATTTTCGAAGTTATTCCATTCCTTGTACTT
GCTGTTGGTGTCGATAACATTTTCATTCTTGTTCAAACACATCAACGTGATCAAAAGCGT
CCCAATGAAACTCATGCTGAACATATAGGAAGAATTTTAGGAAAAGTAGGACCATCAATT
TTACTTTCATCGATTAGCGAGTCTACTTGCTTTTTCCTTGGTGGACTGTCTGACATGCCC
GCGGTCAAATGCTTTGCCTTATATGCAGGAATGGCTCTATTTTTCGATTTTCTTCTTCAA
ATTACATGTTTCGTGAGTTTATTAGCTTTAGACACTCAACGACAAGCAGAAAATCGATGG
GATATTCTTTGCTTCATGCGAGGCTCAAAGAAAGATTCAGGACAGATTACGACATCGAAA
GAAGGAGTGCTTTATAAATTTTTCAAAGTTATTTATGTGCCTTTTTTGATGAAAAAAGTA
GTTCGAATAACAGTGATGGTAGTTTTCTATGGGTGGCTTTGTTCGAGTATTGCTGTTGCA
CCGCACATTGACATCGGTCTCGACCAAGAGCTCTCAATGCCAAAGGATTCATTTGTGCTT
AAATATTTCCAATATCTGCAAAGCTACTTGTCTGTTGGACCGCCGACTTATTTTGTTCTT
AAAAATGGATTAAATTTTTCAAATACTCAAGATCAGAATCTTATCTGTGGTGGACTTTAT
TGTAATTCAGACAGTTTGTACACGCAAATTTACAGTTCATCAAAACTACCTGAAACAACT
TTCATTGCACGTCCAGCAAGTAGCTGGATTGATGATTATTTCGATTGGTCACAACTTGAA
CAATGTTGTCGACAAAATTCAAATGGTTCTTTCTGTCCTCATTCAGATGGAGATTGCAAA
CCATGCTCGATTTCAAGAAATAACATAAAGAGACCAATACCAAAAGATTTCAACAAATAT
GTGAGCTTTTTCCTCAATGACAATCCCGATGAAACATGTGCTAAAGGTGGCCATGCGGCA
TACTATTCTGCTGTAAATCTCTTGGAAAATAAAACACAAGCAGTTGGTGCAAGTTATTTC
ATGACATATCATACAATTCTTAAAACATCATCGGACTATTTTGAAGCATTAAGGGCAGCA
AGAAAAGTGTCTGCCAACATTACAAAAACAATTCATGCATCGATGCGACTTTCAGGCAGA
CCAGAATCTGAAATTGAAAATGTTGAAGTATTTCCATATTCTGTTTTCTATGTTTTCTAC
GAACAGTATCTTACAATGTGGCCTGATACAGTACGCAGTATGGGAATTTCTGTTTTATCA
ATTTTCATCGTAACATTCCTTCTCATGGGCTTCGACATTCATTCATCAATTGTTGTTGTT
ATCACAATTACAATGATAGTCATCAACATTGGAGGACTTATGTATTATTGGAATATCTCA
TTGAATGCTGTTTCATTGGTTAATCTTGTTATGGCTGTCGGCATTTCTGTTGAATTCTGC
TCGCATCTTGTGCATAGCTTTAGCGTTTCTATGGAAGAAACAAAAGTTAAAAGGTCAGCT
GATGCTTTAACTAAAATGGGCAGCTCGATATTTTCGGGTATTACATTAACTAAATTCGGT
GGGATACTTGTGTTGGGTTTTGCACAAAGTCAAATTTTCCAAGTTTTCTACTTCCGTATG
TATCTTGGAATTGTACTATTTGGTGCAGCTCATGGCCTCATCTTCTTGCCAGTTTTATTA
TCATATATTGGCGCTCCAATAAATAAGGCAAAGCTGGCACAGTATCGACGAAAAGCAAAG
GAGATGCAGGAAACATCGTTATCAACTGCGTGA
>g12300.t3 Gene=g12300 Length=1310
MSIRFKTNLINFILILGFSLVFGQATTTTSSTDNEGHCVWRGICATDPQKKNCAYDGKAL
PLDKEGITELQEWCSHLMPNSNNSTVLTCCDIEQLKEFNSQIKLAAAILNRCPSCMKNLA
RHICDFTCSPHQSDFIKVKKTGISEDTNKTYVDEIDIYITEKYFNGTYDSCKNVIYPSSG
QLALDLMCGSWGASKCSPARWFGYMGDAVNNPFVPFQINYLPQDSSSRNDDIKPLDSKVV
PCNQPVDDKTPACSCVDCQASCPKPPPPDPVVRPFIIWGFDGYAVVMFFIFLLGSLIFIM
GAGCCSTSETGQSSENDQELTTHPSAIVDNELGEESGYFEKLGAKTEHVLEQFFTAWGTW
CANNPWKVLLLGCIFIASLGFGLLFLNVTTDPVQLWASPHSRSRIEREYFDTHFGPFYRI
EQIIITTKDIAPIVHNTSNGIVHFGPVFNDTFLLKVREIQESIKSIKLQNSDDDEALSKI
CYAPLRSQYFEEDQSQSVNDCVIQSVWGYFKDDIDTFEEIDTDSEGYTINYLDHLLQCFN
NPYNPDCLAPYGGIVDPAVAFGGFLKPGDTLSKNPNYENATSVILTFLVNNNHDKTKLND
TLNWEEMYVKVMKNWTTNANISFMDIAFTSERSIEDELYRESKSDISTILVSYLLMFAYI
AVSLGHVDVCNRALIDSKITLGMGGVIIVLASVVASGGFFGYIGVPATLIIFEVIPFLVL
AVGVDNIFILVQTHQRDQKRPNETHAEHIGRILGKVGPSILLSSISESTCFFLGGLSDMP
AVKCFALYAGMALFFDFLLQITCFVSLLALDTQRQAENRWDILCFMRGSKKDSGQITTSK
EGVLYKFFKVIYVPFLMKKVVRITVMVVFYGWLCSSIAVAPHIDIGLDQELSMPKDSFVL
KYFQYLQSYLSVGPPTYFVLKNGLNFSNTQDQNLICGGLYCNSDSLYTQIYSSSKLPETT
FIARPASSWIDDYFDWSQLEQCCRQNSNGSFCPHSDGDCKPCSISRNNIKRPIPKDFNKY
VSFFLNDNPDETCAKGGHAAYYSAVNLLENKTQAVGASYFMTYHTILKTSSDYFEALRAA
RKVSANITKTIHASMRLSGRPESEIENVEVFPYSVFYVFYEQYLTMWPDTVRSMGISVLS
IFIVTFLLMGFDIHSSIVVVITITMIVINIGGLMYYWNISLNAVSLVNLVMAVGISVEFC
SHLVHSFSVSMEETKVKRSADALTKMGSSIFSGITLTKFGGILVLGFAQSQIFQVFYFRM
YLGIVLFGAAHGLIFLPVLLSYIGAPINKAKLAQYRRKAKEMQETSLSTA
Protein features from InterProScan
| Transcript | Database | ID | Name | Start | End | E.value | |
|---|---|---|---|---|---|---|---|
| 8 | g12300.t3 | Gene3D | G3DSA:1.20.1640.10 | Multidrug efflux transporter AcrB transmembrane domain | 1114 | 1299 | 2.2E-11 |
| 4 | g12300.t3 | PANTHER | PTHR45727 | NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1 | 29 | 1305 | 0.0 |
| 1 | g12300.t3 | Pfam | PF16414 | Niemann-Pick C1 N terminus | 36 | 281 | 2.2E-75 |
| 2 | g12300.t3 | Pfam | PF12349 | Sterol-sensing domain of SREBP cleavage-activation | 675 | 827 | 1.5E-57 |
| 3 | g12300.t3 | Pfam | PF02460 | Patched family | 1106 | 1282 | 4.3E-33 |
| 24 | g12300.t3 | Phobius | SIGNAL_PEPTIDE | Signal peptide region | 1 | 25 | - |
| 25 | g12300.t3 | Phobius | SIGNAL_PEPTIDE_N_REGION | N-terminal region of a signal peptide. | 1 | 8 | - |
| 26 | g12300.t3 | Phobius | SIGNAL_PEPTIDE_H_REGION | Hydrophobic region of a signal peptide. | 9 | 20 | - |
| 41 | g12300.t3 | Phobius | SIGNAL_PEPTIDE_C_REGION | C-terminal region of a signal peptide. | 21 | 25 | - |
| 22 | g12300.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 26 | 274 | - |
| 40 | g12300.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 275 | 299 | - |
| 11 | g12300.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 300 | 367 | - |
| 33 | g12300.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 368 | 386 | - |
| 17 | g12300.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 387 | 645 | - |
| 37 | g12300.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 646 | 667 | - |
| 15 | g12300.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 668 | 678 | - |
| 31 | g12300.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 679 | 703 | - |
| 18 | g12300.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 704 | 708 | - |
| 29 | g12300.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 709 | 731 | - |
| 10 | g12300.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 732 | 751 | - |
| 28 | g12300.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 752 | 774 | - |
| 19 | g12300.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 775 | 785 | - |
| 36 | g12300.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 786 | 810 | - |
| 13 | g12300.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 811 | 859 | - |
| 35 | g12300.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 860 | 882 | - |
| 16 | g12300.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 883 | 901 | - |
| 30 | g12300.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 902 | 920 | - |
| 12 | g12300.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 921 | 1133 | - |
| 38 | g12300.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1134 | 1151 | - |
| 20 | g12300.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1152 | 1156 | - |
| 27 | g12300.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1157 | 1177 | - |
| 14 | g12300.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1178 | 1188 | - |
| 39 | g12300.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1189 | 1209 | - |
| 23 | g12300.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1210 | 1228 | - |
| 34 | g12300.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1229 | 1248 | - |
| 9 | g12300.t3 | Phobius | CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the cytoplasm. | 1249 | 1259 | - |
| 32 | g12300.t3 | Phobius | TRANSMEMBRANE | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1260 | 1283 | - |
| 21 | g12300.t3 | Phobius | NON_CYTOPLASMIC_DOMAIN | Region of a membrane-bound protein predicted to be outside the membrane, in the extracellular region. | 1284 | 1310 | - |
| 59 | g12300.t3 | ProSiteProfiles | PS50156 | Sterol-sensing domain (SSD) profile. | 645 | 810 | 39.564 |
| 5 | g12300.t3 | SUPERFAMILY | SSF82866 | Multidrug efflux transporter AcrB transmembrane domain | 606 | 810 | 1.1E-18 |
| 6 | g12300.t3 | SUPERFAMILY | SSF82866 | Multidrug efflux transporter AcrB transmembrane domain | 1112 | 1284 | 3.01E-20 |
| 7 | g12300.t3 | SignalP_EUK | SignalP-noTM | SignalP-noTM | 1 | 23 | - |
| 42 | g12300.t3 | SignalP_GRAM_NEGATIVE | SignalP-noTM | SignalP-noTM | 1 | 23 | - |
| 58 | g12300.t3 | TIGRFAM | TIGR00917 | 2A060601: Niemann-Pick C type protein family | 38 | 1284 | 0.0 |
| 50 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 7 | 26 | - |
| 54 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 277 | 299 | - |
| 55 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 368 | 390 | - |
| 48 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 648 | 670 | - |
| 51 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 683 | 705 | - |
| 46 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 709 | 731 | - |
| 45 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 751 | 773 | - |
| 49 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 788 | 810 | - |
| 43 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 861 | 883 | - |
| 53 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 898 | 920 | - |
| 57 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1131 | 1153 | - |
| 56 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1157 | 1179 | - |
| 47 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1184 | 1206 | - |
| 52 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1226 | 1248 | - |
| 44 | g12300.t3 | TMHMM | TMhelix | Region of a membrane-bound protein predicted to be embedded in the membrane. | 1261 | 1283 | - |
Transmembrane regions from TMHMM
Disordered region
IUPRED3 score over 0.5 is predictive of a disordered region.
GO terms from InterProScan
| GOID | TERM | ONTOLOGY |
|---|---|---|
| GO:0005319 | lipid transporter activity | MF |
| GO:0016021 | integral component of membrane | CC |
KEGG
Orthology
- This transcript has been annotated with K12385 (Niemann-Pick C1 protein)
Pathway
- This transcript belongs to the following pathways
Expression
Transcript expression in Pv11 cells
TPM values are indicated as average +/- STDEV. 
Differential expression
Differentially expressed genes were identified with DESeq2 using the ‘run_DE_analysis.pl’ script from Trinity. Transcripts were determined as differentially expressed when (1) FDR < 0.05 (2) fold change > 2 (TPM calculated by RSEM). DE information and fold change between conditions are indicated in the plot below.
